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pyridoxal phosphate and Cancer of Pancreas

pyridoxal phosphate has been researched along with Cancer of Pancreas in 24 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Research Excerpts

ExcerptRelevanceReference
"Manganese (II) N,N'-dipyridoxylethylenediamine-N,N'-diacetate 5,5'-bis(phosphate) (DPDP) was tested as a contrast agent for magnetic resonance imaging of pancreatic adenocarcinoma in 15 patients."5.07Mn-DPDP in MR imaging of pancreatic adenocarcinoma: initial clinical experience. ( Bohndorf, K; Gehl, HB; Günther, RW; Hauptmann, S; Klever, P; Lodemann, KP; Matern, S; Schumpelick, V; Urhahn, R, 1993)
" Conditional logistic regression was used to calculate the odds ratios (OR) and 95% confidence intervals (CI), adjusting for education, smoking status, plasma cotinine concentration, alcohol drinking, body mass index and diabetes status."3.77A U-shaped relationship between plasma folate and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition. ( Benetou, V; Boeing, H; Boutron-Ruault, MC; Bueno-de-Mesquita, B; Chuang, SC; Clavel-Chapelon, F; Crowe, F; Duell, EJ; Gurrea, AB; Huerta, JM; Jenab, M; Jeurnink, S; Johansen, D; Kaaks, R; Khaw, KT; Larrañaga, N; Manjer, J; Michaud, DS; Midttun, Ø; Molina-Montes, E; Morois, S; Naska, A; Olsen, A; Overvad, K; Palli, D; Panico, S; Peeters, PH; Riboli, E; Rodriguez, L; Romieu, I; Sacerdote, C; Sieri, S; Skeie, G; Slimani, N; Stolzenberg-Solomon, R; Sund, M; Teucher, B; Tjønneland, A; Trichopoulou, A; Tumino, R; Ueland, PM; Vineis, P; Vollset, SE; Wareham, N; Weikert, C; Ye, W, 2011)
"20 patients with suspected pancreatic cancer were included in a phase III study."2.69MRI with mangafodipir trisodium in the detection of pancreatic tumours: comparison with helical CT. ( Brambs, HJ; Klaus, H; Nüssle, K; Rieber, A; Tomczak, R, 2000)
"Insulinoma is the most common pancreatic endocrine tumor."2.42Mangan-enhanced MR imaging for the detection and localisation of small pancreatic insulinoma. ( Aboalmaali, N; Hamoud, AK; Khan, MF; Usadel, KH; Vogl, TJ; Wullstein, C, 2004)
"Mangafodopir may improve the staging of pancreatic cancer by increasing the sensitivity of MRI in the detection of liver metastases."2.41Evaluation of focal pancreatic masses: comparison of mangafodipir-enhanced MR imaging and contrast-enhanced helical CT. ( Függer, R; Schima, W, 2002)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (33.33)18.2507
2000's13 (54.17)29.6817
2010's3 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, JY2
Butler, LM2
Midttun, Ø3
Ulvik, A1
Wang, R2
Jin, A2
Gao, YT2
Ueland, PM3
Koh, WP2
Yuan, JM2
Boraschi, P1
Donati, F1
Gigoni, R1
Salemi, S1
Faggioni, L1
Del Chiaro, M1
Boggi, U1
Bartolozzi, C1
Falaschi, F1
Chuang, SC1
Stolzenberg-Solomon, R1
Vollset, SE1
Olsen, A1
Tjønneland, A1
Overvad, K1
Boutron-Ruault, MC1
Morois, S1
Clavel-Chapelon, F1
Teucher, B1
Kaaks, R1
Weikert, C1
Boeing, H1
Trichopoulou, A1
Benetou, V1
Naska, A1
Jenab, M1
Slimani, N1
Romieu, I1
Michaud, DS1
Palli, D1
Sieri, S1
Panico, S1
Sacerdote, C1
Tumino, R1
Skeie, G1
Duell, EJ1
Rodriguez, L1
Molina-Montes, E1
Huerta, JM1
Larrañaga, N1
Gurrea, AB1
Johansen, D1
Manjer, J1
Ye, W1
Sund, M1
Peeters, PH1
Jeurnink, S1
Wareham, N1
Khaw, KT1
Crowe, F1
Riboli, E1
Bueno-de-Mesquita, B1
Vineis, P1
Schima, W4
Függer, R2
Schober, E1
Oettl, C1
Wamser, P1
Grabenwöger, F1
Ryan, JM1
Novacek, G1
Hamoud, AK1
Khan, MF1
Aboalmaali, N1
Usadel, KH1
Wullstein, C1
Vogl, TJ1
Ramsay, D1
Marshall, M1
Song, S1
Zimmerman, M1
Edmunds, S1
Yusoff, I1
Cullingford, G1
Fletcher, D1
Mendelson, R1
Zanello, A1
Nicoletti, R1
Brambilla, P1
Boccuni, R1
Di Carlo, V1
Staudacher, C1
Del Maschio, A1
Sahani, DV1
Kalva, SP1
Fischman, AJ1
Kadavigere, R1
Blake, M1
Hahn, PF1
Saini, S2
Eser, G1
Karabacakoglu, A1
Karakose, S1
Eser, C1
Kayacetin, E1
De Filippo, M1
Bocchi, C1
Quartieri, L1
Corradi, D1
Zompatori, M1
Gehl, HB3
Günther, RW2
Klever, P2
Hauptmann, S2
Urhahn, R1
Bohndorf, K1
Lodemann, KP1
Matern, S1
Schumpelick, V1
Kettritz, U1
Semelka, RC1
Ahlström, H1
Mayo-Smith, WW1
Slater, GJ1
McFarland, EG1
Wang, C1
Mathieu, D1
Coffin, C1
Kobeiter, H1
Caseiro-Alves, F1
Mahfouz, A1
Rahmouni, A1
Diche, T1
Diehl, SJ1
Lehmann, KJ1
Gaa, J1
McGill, S1
Hoffmann, V1
Georgi, M1
Romijn, MG1
Stoker, J1
van Eijck, CH1
van Muiswinkel, JM1
Torres, CG1
Laméris, JS1
Rieber, A1
Tomczak, R1
Nüssle, K1
Klaus, H1
Brambs, HJ1
Dobritz, M1
Fellner, FA1
Baum, U1
Nömayr, A1
Lell, M1
Klein, P1
Papadopoulos, T1
Bautz, W1

Reviews

5 reviews available for pyridoxal phosphate and Cancer of Pancreas

ArticleYear
Evaluation of focal pancreatic masses: comparison of mangafodipir-enhanced MR imaging and contrast-enhanced helical CT.
    European radiology, 2002, Volume: 12, Issue:12

    Topics: Contrast Media; Edetic Acid; Humans; Laparotomy; Magnetic Resonance Imaging; Neoplasm Staging; Pancr

2002
Mangan-enhanced MR imaging for the detection and localisation of small pancreatic insulinoma.
    European radiology, 2004, Volume: 14, Issue:5

    Topics: Contrast Media; Edetic Acid; Humans; Insulinoma; Laparoscopy; Magnetic Resonance Imaging; Pancreas;

2004
Contrast-enhanced MR imaging of the pancreas.
    Magnetic resonance imaging clinics of North America, 1996, Volume: 4, Issue:1

    Topics: Contrast Media; Edetic Acid; Gadolinium; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Mangan

1996
Overview of MnDPDP as a pancreas-specific contrast agent for MR imaging.
    Acta radiologica (Stockholm, Sweden : 1987), 1997, Volume: 38, Issue:4 Pt 2

    Topics: Acute Disease; Contrast Media; Edetic Acid; Humans; Magnetic Resonance Imaging; Manganese; Pancreas;

1997
Unexpected MR-T1 enhancement of endocrine liver metastases with mangafodipir.
    Journal of magnetic resonance imaging : JMRI, 1999, Volume: 10, Issue:2

    Topics: Adenoma, Islet Cell; Contrast Media; Edetic Acid; Humans; Liver; Liver Neoplasms; Magnetic Resonance

1999

Trials

6 trials available for pyridoxal phosphate and Cancer of Pancreas

ArticleYear
[Manganese dipyridoxal diphosphate as a new contrast medium in the MRT of benign and malignant pancreatic tumors: initial clinical findings].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1993, Volume: 159, Issue:3

    Topics: Adenocarcinoma; Adenoma, Islet Cell; Chronic Disease; Contrast Media; Edetic Acid; Humans; Magnetic

1993
Mn-DPDP in MR imaging of pancreatic adenocarcinoma: initial clinical experience.
    Radiology, 1993, Volume: 186, Issue:3

    Topics: Adenocarcinoma; Contrast Media; Edetic Acid; Female; Humans; Magnetic Resonance Imaging; Male; Manga

1993
Pancreatic enhancement and pulse sequence analysis using low-dose mangafodipir trisodium.
    AJR. American journal of roentgenology, 1998, Volume: 170, Issue:3

    Topics: Adult; Aged; Contrast Media; Edetic Acid; Female; Humans; Magnetic Resonance Imaging; Male; Manganes

1998
MR imaging of pancreatic lesions. Comparison of manganese-DPDP and gadolinium chelate.
    Investigative radiology, 1999, Volume: 34, Issue:9

    Topics: Adult; Aged; Carcinoma, Ductal, Breast; Chronic Disease; Contrast Media; Diagnosis, Differential; Ed

1999
MRI with mangafodipir trisodium in the detection and staging of pancreatic cancer.
    Journal of magnetic resonance imaging : JMRI, 2000, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Diagnosis, Differential; Edetic Acid; Female; Humans

2000
MRI with mangafodipir trisodium in the detection of pancreatic tumours: comparison with helical CT.
    The British journal of radiology, 2000, Volume: 73, Issue:875

    Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Edetic Acid; Female; Humans; Image Processing, Compu

2000

Other Studies

13 other studies available for pyridoxal phosphate and Cancer of Pancreas

ArticleYear
A prospective evaluation of serum kynurenine metabolites and risk of pancreatic cancer.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: 3-Hydroxyanthranilic Acid; Biomarkers; Case-Control Studies; China; Female; Humans; Kynurenine; Male

2018
Serum B
    Cancer causes & control : CCC, 2016, Volume: 27, Issue:12

    Topics: Aged; Asian People; Biomarkers, Tumor; Case-Control Studies; Female; Humans; Male; Middle Aged; Panc

2016
Secretin-stimulated multi-detector CT versus mangafodipir trisodium-enhanced MR imaging plus MRCP in characterization of non-metastatic solid pancreatic lesions.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2009, Volume: 41, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Contrast Media; Edetic Acid; Humans; Magnetic Resonance Ima

2009
A U-shaped relationship between plasma folate and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition.
    European journal of cancer (Oxford, England : 1990), 2011, Volume: 47, Issue:12

    Topics: Adult; Aged; Alcohol Drinking; Body Mass Index; Case-Control Studies; Cotinine; Diabetes Complicatio

2011
Diagnosis and staging of pancreatic cancer: comparison of mangafodipir trisodium-enhanced MR imaging and contrast-enhanced helical hydro-CT.
    AJR. American journal of roentgenology, 2002, Volume: 179, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Contrast Media; Diagnosis, Differential; Edetic Acid

2002
[Organ specific MRI contrast media in general practice].
    Wiener medizinische Wochenschrift. Supplement, 2002, Issue:113

    Topics: Contrast Media; Dextrans; Edetic Acid; Ferrosoferric Oxide; Humans; Iron; Liver Neoplasms; Lung Neop

2002
Identification and staging of pancreatic tumours using computed tomography, endoscopic ultrasound and mangafodipir trisodium-enhanced magnetic resonance imaging.
    Australasian radiology, 2004, Volume: 48, Issue:2

    Topics: Contrast Media; Edetic Acid; Endosonography; Female; Humans; Lymphatic Metastasis; Magnetic Resonanc

2004
Magnetic resonance with manganese-DPDP (mangafodipir) of focal solid pancreatic lesions.
    La Radiologia medica, 2004, Volume: 108, Issue:3

    Topics: Adult; Aged; Contrast Media; Edetic Acid; Female; Humans; Magnetic Resonance Imaging; Male; Middle A

2004
Detection of liver metastases from adenocarcinoma of the colon and pancreas: comparison of mangafodipir trisodium-enhanced liver MRI and whole-body FDG PET.
    AJR. American journal of roentgenology, 2005, Volume: 185, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Contrast Media; Edetic Acid; Female; Fluorodeoxygluc

2005
Mangafodipir trisodium-enhanced magnetic resonance imaging for evaluation of pancreatic mass and mass-like lesions.
    World journal of gastroenterology, 2006, Mar-14, Volume: 12, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Contrast Media; Edetic Acid; Female; Humans; Liver N

2006
Mangafodipir-DPDP enhanced MRI visualization of a pancreatic adenocarcinoma previously undetected by extracellular contrast enhanced CT and MRI.
    Acta bio-medica : Atenei Parmensis, 2007, Volume: 78, Issue:3

    Topics: Adenocarcinoma; Cholangiopancreatography, Endoscopic Retrograde; Contrast Media; Edetic Acid; Female

2007
Mangafodipir trisodium (MnDPDP)-enhanced magnetic resonance imaging of the liver and pancreas.
    Acta radiologica. Supplementum, 1998, Volume: 415

    Topics: Adenocarcinoma; Adenoma, Islet Cell; Adipose Tissue; Adult; Aged; Aged, 80 and over; Blood-Brain Bar

1998
[MR imaging of pancreatic lesions with Mn-DPDP. A histopathologic correlation].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2002, Volume: 174, Issue:7

    Topics: Ampulla of Vater; Biopsy, Needle; Common Bile Duct Neoplasms; Contrast Media; Edetic Acid; Humans; I

2002