pyridoxal phosphate has been researched along with Breast Neoplasms in 10 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epidemiological studies evaluating the association of vitamin B6, vitamin B12 and methionine with breast cancer risk have produced inconsistent results." | 8.89 | Association of vitamin B6, vitamin B12 and methionine with risk of breast cancer: a dose-response meta-analysis. ( Kang, S; Wu, W; Zhang, D, 2013) |
| " The objective of this study was to determine the associations between folate, cobalamin, and pyridoxine with fasting plasma tHcy concentration in breast cancer (BC) patients." | 7.80 | Plasma total homocysteine level in association with folate, pyridoxine, and cobalamin status among Iranian primary breast cancer patients. ( Atri, M; Foroutan-Ghaznavi, M; Mehdipour, P; Pirouzpanah, S; Taleban, FA, 2014) |
| "The increased risk of breast cancer associated with high cysteine levels warrants further investigation." | 5.36 | Plasma homocysteine and cysteine and risk of breast cancer in women. ( Buring, JE; Cook, NR; Lee, IM; Lin, J; Manson, JE; Selhub, J; Song, Y; Zhang, SM, 2010) |
| "Epidemiological studies evaluating the association of vitamin B6, vitamin B12 and methionine with breast cancer risk have produced inconsistent results." | 4.89 | Association of vitamin B6, vitamin B12 and methionine with risk of breast cancer: a dose-response meta-analysis. ( Kang, S; Wu, W; Zhang, D, 2013) |
| " In the general population, evidence has suggested that high circulating folate and folic acid (synthetic form of folate) supplement use may increase breast cancer risk, but the role of folate in BRCA-associated breast cancer is not clear." | 3.83 | Plasma folate, vitamin B-6, and vitamin B-12 and breast cancer risk in BRCA1- and BRCA2-mutation carriers: a prospective study. ( Akbari, MR; Demsky, R; Eisen, A; Kim, SJ; Kim, YI; Kotsopoulos, J; Lubinski, J; Narod, SA; Sohn, KJ; Zuchniak, A, 2016) |
| " The objective of this study was to determine the associations between folate, cobalamin, and pyridoxine with fasting plasma tHcy concentration in breast cancer (BC) patients." | 3.80 | Plasma total homocysteine level in association with folate, pyridoxine, and cobalamin status among Iranian primary breast cancer patients. ( Atri, M; Foroutan-Ghaznavi, M; Mehdipour, P; Pirouzpanah, S; Taleban, FA, 2014) |
| "The plasma pyridoxal phosphate concentration was determined in 30 cases of early breast cancer, 21 patients with locally recurrent disease, and 43 patients with systemic metastases." | 3.65 | Vitamin B6 deficiency in cancer patients. ( Brown, RR; Potera, C; Rose, DP, 1977) |
| "The increased risk of breast cancer associated with high cysteine levels warrants further investigation." | 1.36 | Plasma homocysteine and cysteine and risk of breast cancer in women. ( Buring, JE; Cook, NR; Lee, IM; Lin, J; Manson, JE; Selhub, J; Song, Y; Zhang, SM, 2010) |
| "To investigate the incidence of breast cancer and prediagnostic serum levels of folate, B12, and pyridoxal 5'-phosphate (B6), we conducted a nested case-control study using resources from the Washington County (Maryland) serum bank." | 1.30 | A prospective study on folate, B12, and pyridoxal 5'-phosphate (B6) and breast cancer. ( Comstock, GW; Helzlsouer, KJ; Hoffman, SC; Nadeau, MR; Selhub, J; Wu, K, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, W | 1 |
| Kang, S | 1 |
| Zhang, D | 1 |
| Pirouzpanah, S | 1 |
| Taleban, FA | 1 |
| Mehdipour, P | 1 |
| Atri, M | 1 |
| Foroutan-Ghaznavi, M | 1 |
| Kim, SJ | 1 |
| Zuchniak, A | 1 |
| Sohn, KJ | 1 |
| Lubinski, J | 1 |
| Demsky, R | 1 |
| Eisen, A | 1 |
| Akbari, MR | 1 |
| Kim, YI | 1 |
| Narod, SA | 1 |
| Kotsopoulos, J | 1 |
| Lin, J | 1 |
| Lee, IM | 1 |
| Song, Y | 1 |
| Cook, NR | 1 |
| Selhub, J | 3 |
| Manson, JE | 1 |
| Buring, JE | 1 |
| Zhang, SM | 1 |
| Burkill, GJ | 1 |
| King, LJ | 1 |
| Scurr, E | 1 |
| Healy, JC | 1 |
| BEREZOV, TT | 1 |
| DOBRININ, YV | 1 |
| Wu, K | 2 |
| Helzlsouer, KJ | 2 |
| Comstock, GW | 1 |
| Hoffman, SC | 1 |
| Nadeau, MR | 1 |
| Goodman, JE | 1 |
| Lavigne, JA | 1 |
| Strickland, PT | 1 |
| Yager, JD | 1 |
| Helmberger, TK | 1 |
| Laubenberger, J | 1 |
| Rummeny, E | 1 |
| Jung, G | 1 |
| Sievers, K | 1 |
| Döhring, W | 1 |
| Meurer, K | 1 |
| Reiser, MF | 1 |
| Potera, C | 1 |
| Rose, DP | 1 |
| Brown, RR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Folic Acid Clinical Trial (FACT): Biomarker Subgroup Analysis[NCT03981029] | 51 participants (Actual) | Observational | 2011-12-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyridoxal phosphate and Breast Neoplasms
| Article | Year |
|---|---|
Association of vitamin B6, vitamin B12 and methionine with risk of breast cancer: a dose-response meta-analysis.
Topics: Breast Neoplasms; Diet; Dose-Response Relationship, Drug; Female; Humans; Methionine; Pyridoxal Phos | 2013 |
1 trial available for pyridoxal phosphate and Breast Neoplasms
| Article | Year |
|---|---|
MRI characteristics in focal hepatic disease before and after administration of MnDPDP: discriminant analysis as a diagnostic tool.
Topics: Adolescent; Adult; Aged; Breast Neoplasms; Carcinoma, Hepatocellular; Colorectal Neoplasms; Contrast | 2002 |
8 other studies available for pyridoxal phosphate and Breast Neoplasms
| Article | Year |
|---|---|
Plasma total homocysteine level in association with folate, pyridoxine, and cobalamin status among Iranian primary breast cancer patients.
Topics: Adult; Aged; Biomarkers; Body Mass Index; Breast Neoplasms; Fasting; Female; Folic Acid; Homocystein | 2014 |
Plasma folate, vitamin B-6, and vitamin B-12 and breast cancer risk in BRCA1- and BRCA2-mutation carriers: a prospective study.
Topics: Adult; Biomarkers; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Cohort Studies; Dietary Supplemen | 2016 |
Plasma homocysteine and cysteine and risk of breast cancer in women.
Topics: Breast Neoplasms; Case-Control Studies; Cysteine; Female; Folic Acid; Homocysteine; Humans; Middle A | 2010 |
Breast carcinoma metastases to the liver simulating cirrhosis.
Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Contrast Media; Edetic Acid; Female; Humans; Liver Cirr | 2002 |
THE RANGE OF TRANSAMINATION IN CARCINOMA CELLS OF MAMMARY GLAND IN TISSUE CULTURE.
Topics: Alanine Transaminase; Amination; Amino Acids; Animals; Aspartate Aminotransferases; Breast Neoplasms | 1964 |
A prospective study on folate, B12, and pyridoxal 5'-phosphate (B6) and breast cancer.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Case-Control Studies; Cohort Studies; | 1999 |
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.
Topics: Breast Neoplasms; Case-Control Studies; Catechol O-Methyltransferase; Cysteine; Estrogens, Catechol; | 2001 |
Vitamin B6 deficiency in cancer patients.
Topics: Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Genital Neoplasms, Female; Humans; Middle | 1977 |