pyridoxal phosphate has been researched along with Brain Ischemia in 6 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epidemiological studies have described an association between low vitamin B6 (measured as pyridoxal 5'-phosphate [PLP]) and ischemic stroke, independent of homocysteine (tHcy)." | 7.72 | Inflammation, homocysteine, and vitamin B6 status after ischemic stroke. ( Atassi, N; Barron, M; Furie, KL; Kelly, PJ; Kistler, JP; Lee, H; Mandell, R; Shih, VE; Silveira, S, 2004) |
| "Epidemiological studies have described an association between low vitamin B6 (measured as pyridoxal 5'-phosphate [PLP]) and ischemic stroke, independent of homocysteine (tHcy)." | 3.72 | Inflammation, homocysteine, and vitamin B6 status after ischemic stroke. ( Atassi, N; Barron, M; Furie, KL; Kelly, PJ; Kistler, JP; Lee, H; Mandell, R; Shih, VE; Silveira, S, 2004) |
| " In the present project, the authors have studied whether MC-1, an analog of PLP, alone or in combination with the thrombolytic agent tissue plasminogen activator (tPA), can protect the brains of rats injured by ischemia." | 1.33 | Role of MC-1 alone and in combination with tissue plasminogen activator in focal ischemic brain injury in rats. ( Noor, R; Shuaib, A; Wang, CX; Yang, T, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, W | 1 |
| Yao, J | 1 |
| Pham, V | 1 |
| Whitney, T | 1 |
| Froese, D | 1 |
| Friesen, A | 1 |
| Stang, L | 1 |
| Xu, C | 1 |
| Shuaib, A | 2 |
| Diakur, JM | 1 |
| Haque, W | 1 |
| Kelly, PJ | 1 |
| Kistler, JP | 1 |
| Shih, VE | 1 |
| Mandell, R | 1 |
| Atassi, N | 1 |
| Barron, M | 1 |
| Lee, H | 1 |
| Silveira, S | 1 |
| Furie, KL | 1 |
| Wang, CX | 1 |
| Yang, T | 1 |
| Noor, R | 1 |
| Lämmer, A | 1 |
| Günther, A | 1 |
| Beck, A | 1 |
| Krügel, U | 1 |
| Kittner, H | 1 |
| Schneider, D | 1 |
| Illes, P | 1 |
| Franke, H | 1 |
| Hwang, IK | 1 |
| Yoo, KY | 1 |
| Kim, DH | 1 |
| Lee, BH | 1 |
| Kwon, YG | 1 |
| Won, MH | 1 |
| Yamashima, T | 1 |
| Zhao, L | 1 |
| Wang, XD | 1 |
| Tsukada, T | 1 |
| Tonchev, AB | 1 |
6 other studies available for pyridoxal phosphate and Brain Ischemia
| Article | Year |
|---|---|
Pyridoxine as a template for the design of antiplatelet agents.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Humans; In Vitro Techniques; Intracranial Thrombosi | 2004 |
Inflammation, homocysteine, and vitamin B6 status after ischemic stroke.
Topics: Aged; Brain Ischemia; C-Reactive Protein; Comorbidity; Female; Homocysteine; Humans; Inflammation; M | 2004 |
Role of MC-1 alone and in combination with tissue plasminogen activator in focal ischemic brain injury in rats.
Topics: Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Dose-R | 2005 |
Neuroprotective effects of the P2 receptor antagonist PPADS on focal cerebral ischaemia-induced injury in rats.
Topics: Animals; Brain; Brain Ischemia; Immunohistochemistry; Injections, Intraventricular; Male; Neuroprote | 2006 |
Time course of changes in pyridoxal 5'-phosphate (vitamin B6 active form) and its neuroprotection in experimental ischemic damage.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Animals; Astrocytes; Brain Infarction; Brain | 2007 |
Neuroprotective effects of pyridoxal phosphate and pyridoxal against ischemia in monkeys.
Topics: Animals; Brain Ischemia; Cathepsin B; Cathepsin L; Cathepsins; Cell Death; Cysteine Endopeptidases; | 2001 |