pyridoxal phosphate has been researched along with Brain Injuries in 4 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reactive gliosis is a process triggered in astrocytes after traumatic injury, yet the exact consequences of gliosis on cellular survival and neural regenerative processes in the injured brain remain only partly understood." | 1.35 | Mechanically induced reactive gliosis causes ATP-mediated alterations in astrocyte stiffness. ( Haydon, PG; Janmey, P; Leventhal, I; Meaney, DF; Miller, WJ; Scarsella, D, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franke, H | 2 |
| Sauer, C | 1 |
| Rudolph, C | 1 |
| Krügel, U | 2 |
| Hengstler, JG | 1 |
| Illes, P | 2 |
| Miller, WJ | 1 |
| Leventhal, I | 1 |
| Scarsella, D | 1 |
| Haydon, PG | 1 |
| Janmey, P | 1 |
| Meaney, DF | 1 |
| Neary, JT | 1 |
| Kang, Y | 1 |
| Tran, M | 1 |
| Feld, J | 1 |
| Kittner, H | 1 |
4 other studies available for pyridoxal phosphate and Brain Injuries
| Article | Year |
|---|---|
P2 receptor-mediated stimulation of the PI3-K/Akt-pathway in vivo.
Topics: Adenosine Diphosphate; Androstadienes; Animals; Apoptosis; Astrocytes; Brain Injuries; Disease Model | 2009 |
Mechanically induced reactive gliosis causes ATP-mediated alterations in astrocyte stiffness.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain Injuries; Cells, Cultured; Elasticity; Glial Fibr | 2009 |
Traumatic injury activates protein kinase B/Akt in cultured astrocytes: role of extracellular ATP and P2 purinergic receptors.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Brain Injuries; Calcium Channels; Cel | 2005 |
Accelerated functional recovery after neuronal injury by P2 receptor blockade.
Topics: Animals; Brain Injuries; Electroencephalography; Male; Nucleus Accumbens; Purinergic P2 Receptor Ant | 2001 |