pyridoxal phosphate has been researched along with Atrophy in 6 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Deficit of human ornithine aminotransferase (hOAT), a mitochondrial tetrameric pyridoxal-5'-phosphate (PLP) enzyme, leads to gyrate atrophy of the choroid and retina (GA)." | 8.31 | Biochemical and Bioinformatic Studies of Mutations of Residues at the Monomer-Monomer Interface of Human Ornithine Aminotransferase Leading to Gyrate Atrophy of Choroid and Retina. ( Borri Voltattorni, C; Cellini, B; Floriani, F; Montioli, R, 2023) |
| "A sensitive and convenient radioisotopic assay for ornithine aminotransferase (OAT) and an enzyme immunoassay for human ornithine aminotransferase were developed for studying decrease in activity of this enzyme in gyrate atrophy of the choroid and retina with hyperornithinemia." | 7.67 | Gyrate atrophy of the choroid and retina: decreased ornithine aminotransferase concentration in cultured skin fibroblasts from patients. ( Katunuma, N; Kominami, E; Ohura, T; Tada, K, 1984) |
| "Gyrate atrophy of the choroid and retina is a chorioretinal degeneration associated with hyperornithinemia with an autosomal recessive mode of inheritance." | 7.66 | Ornithine ketoacid transaminase deficiency in gyrate atrophy of the choroid and retina. ( Berson, EL; Mandell, R; Schmidt, SY; Shih, VE, 1978) |
| "Deficit of human ornithine aminotransferase (hOAT), a mitochondrial tetrameric pyridoxal-5'-phosphate (PLP) enzyme, leads to gyrate atrophy of the choroid and retina (GA)." | 4.31 | Biochemical and Bioinformatic Studies of Mutations of Residues at the Monomer-Monomer Interface of Human Ornithine Aminotransferase Leading to Gyrate Atrophy of Choroid and Retina. ( Borri Voltattorni, C; Cellini, B; Floriani, F; Montioli, R, 2023) |
| "A sensitive and convenient radioisotopic assay for ornithine aminotransferase (OAT) and an enzyme immunoassay for human ornithine aminotransferase were developed for studying decrease in activity of this enzyme in gyrate atrophy of the choroid and retina with hyperornithinemia." | 3.67 | Gyrate atrophy of the choroid and retina: decreased ornithine aminotransferase concentration in cultured skin fibroblasts from patients. ( Katunuma, N; Kominami, E; Ohura, T; Tada, K, 1984) |
| "Gyrate atrophy of the choroid and retina is a chorioretinal degeneration associated with hyperornithinemia with an autosomal recessive mode of inheritance." | 3.66 | Ornithine ketoacid transaminase deficiency in gyrate atrophy of the choroid and retina. ( Berson, EL; Mandell, R; Schmidt, SY; Shih, VE, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Floriani, F | 1 |
| Borri Voltattorni, C | 1 |
| Cellini, B | 1 |
| Montioli, R | 1 |
| Jia, C | 1 |
| Roman, C | 1 |
| Hegg, CC | 1 |
| Ohura, T | 1 |
| Kominami, E | 1 |
| Tada, K | 2 |
| Katunuma, N | 1 |
| Hayasaka, S | 1 |
| Saito, T | 1 |
| Nakajima, H | 1 |
| Takaku, Y | 1 |
| Shiono, T | 1 |
| Mizuno, K | 1 |
| Ohmura, K | 1 |
| Shih, VE | 1 |
| Berson, EL | 1 |
| Mandell, R | 1 |
| Schmidt, SY | 1 |
| Jacobs, A | 1 |
| Cavill, I | 1 |
6 other studies available for pyridoxal phosphate and Atrophy
| Article | Year |
|---|---|
Biochemical and Bioinformatic Studies of Mutations of Residues at the Monomer-Monomer Interface of Human Ornithine Aminotransferase Leading to Gyrate Atrophy of Choroid and Retina.
Topics: Atrophy; Choroid; Gyrate Atrophy; Humans; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Pyri | 2023 |
Nickel sulfate induces location-dependent atrophy of mouse olfactory epithelium: protective and proliferative role of purinergic receptor activation.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Atrophy; Cell Proliferation; Cell Survival; Drug Therapy | 2010 |
Gyrate atrophy of the choroid and retina: decreased ornithine aminotransferase concentration in cultured skin fibroblasts from patients.
Topics: Atrophy; Cells, Cultured; Choroid; Clinical Enzyme Tests; Dose-Response Relationship, Drug; Fibrobla | 1984 |
Gyrate atrophy with hyperornithinaemia: different types of responsiveness to vitamin B6.
Topics: Adolescent; Atrophy; Cells, Cultured; Child; Child, Preschool; Choroid; Fibroblasts; Humans; Lymphoc | 1981 |
Ornithine ketoacid transaminase deficiency in gyrate atrophy of the choroid and retina.
Topics: Adolescent; Adult; Atrophy; Cells, Cultured; Child; Choroid; Female; Humans; Male; Ornithine; Ornith | 1978 |
The oral lesions of iron deficiency anaemia: pyridoxine and riboflavin status.
Topics: Adult; Aged; Alanine Transaminase; Anemia, Hypochromic; Atrophy; Humans; Middle Aged; Pyridoxal Phos | 1968 |