pyridoxal phosphate has been researched along with Asthma in 7 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was undertaken to investigate the effect of theophylline on circulating vitamin B6 levels in children with asthma." | 7.69 | Theophylline attenuates circulating vitamin B6 levels in children with asthma. ( Maeda, S; Mochizuki, H; Morikawa, A; Shimizu, T; Tokuyama, K, 1994) |
| "In 15 adult patients with bronchial asthma, plasma and erythrocyte pyridoxal phosphate (PLP) concentrations were significantly lower than in 16 controls (P less than 0." | 7.67 | Depressed plasma pyridoxal phosphate concentrations in adult asthmatics. ( Natta, CL; Reynolds, RD, 1985) |
| "Theophylline was administered to a group of 17 volunteers and resulted in large reductions in plasma pyridoxal-5'-phosphate levels, while plasma pyridoxal levels and urinary 4-pyridoxic acid excretion were unaffected by theophylline therapy." | 5.27 | Vitamin B6 nutritional status in asthma: the effect of theophylline therapy on plasma pyridoxal-5'-phosphate and pyridoxal levels. ( Becker, PJ; Delport, R; Serfontein, WJ; Ubbink, JB; Walters, L, 1988) |
| "Asthmatics treated with theophylline, a potent inhibitor of pyridoxal kinase and therefore a vitamin B6 antagonist, demonstrated a significant correlation (r = 0." | 5.07 | Theophylline increases pyridoxal kinase activity independently from vitamin B6 nutritional status. ( Becker, PJ; Delport, R; Ubbink, JB; Vermaak, WJ, 1993) |
| "This study was undertaken to investigate the effect of theophylline on circulating vitamin B6 levels in children with asthma." | 3.69 | Theophylline attenuates circulating vitamin B6 levels in children with asthma. ( Maeda, S; Mochizuki, H; Morikawa, A; Shimizu, T; Tokuyama, K, 1994) |
| "This study was undertaken to investigate the effect of sustained-release theophylline preparations on circulating vitamin B6 concentrations in children with asthma." | 3.69 | [Serum concentrations of the pyridoxal and pyridoxal-5'-phosphate in children during sustained-release theophylline therapy]. ( Fujino, M; Hiraga, Y; Ito, Y; Kobayashi, K; Tanaka, I, 1996) |
| "In 15 adult patients with bronchial asthma, plasma and erythrocyte pyridoxal phosphate (PLP) concentrations were significantly lower than in 16 controls (P less than 0." | 3.67 | Depressed plasma pyridoxal phosphate concentrations in adult asthmatics. ( Natta, CL; Reynolds, RD, 1985) |
| "Theophylline was administered to a group of 17 volunteers and resulted in large reductions in plasma pyridoxal-5'-phosphate levels, while plasma pyridoxal levels and urinary 4-pyridoxic acid excretion were unaffected by theophylline therapy." | 1.27 | Vitamin B6 nutritional status in asthma: the effect of theophylline therapy on plasma pyridoxal-5'-phosphate and pyridoxal levels. ( Becker, PJ; Delport, R; Serfontein, WJ; Ubbink, JB; Walters, L, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shimizu, T | 1 |
| Maeda, S | 1 |
| Mochizuki, H | 1 |
| Tokuyama, K | 1 |
| Morikawa, A | 1 |
| Delport, R | 3 |
| Ubbink, JB | 3 |
| Vermaak, WJ | 2 |
| Becker, PJ | 2 |
| Tanaka, I | 1 |
| Ito, Y | 1 |
| Hiraga, Y | 1 |
| Fujino, M | 1 |
| Kobayashi, K | 1 |
| Serfontein, WJ | 2 |
| Bartel, P | 1 |
| Walters, L | 1 |
| Keniston, RC | 1 |
| Reynolds, RD | 1 |
| Natta, CL | 1 |
1 review available for pyridoxal phosphate and Asthma
| Article | Year |
|---|---|
The relationship between vitamin B6 metabolism, asthma, and theophylline therapy.
Topics: Asthma; Humans; Pyridoxal Kinase; Pyridoxal Phosphate; Pyridoxine; Theophylline; Vitamin B 6 Deficie | 1990 |
1 trial available for pyridoxal phosphate and Asthma
| Article | Year |
|---|---|
Theophylline increases pyridoxal kinase activity independently from vitamin B6 nutritional status.
Topics: Adult; Aged; Asthma; Dose-Response Relationship, Drug; Double-Blind Method; Erythrocytes; Humans; Mi | 1993 |
5 other studies available for pyridoxal phosphate and Asthma
| Article | Year |
|---|---|
Theophylline attenuates circulating vitamin B6 levels in children with asthma.
Topics: Adolescent; Asthma; Child; Cromolyn Sodium; Delayed-Action Preparations; Female; Humans; Male; Pyrid | 1994 |
[Serum concentrations of the pyridoxal and pyridoxal-5'-phosphate in children during sustained-release theophylline therapy].
Topics: Asthma; Bronchodilator Agents; Child; Delayed-Action Preparations; Female; Humans; Male; Pyridoxal; | 1996 |
Vitamin B6 nutritional status in asthma: the effect of theophylline therapy on plasma pyridoxal-5'-phosphate and pyridoxal levels.
Topics: Adolescent; Adult; Aged; Asthma; Female; Humans; Middle Aged; Nutritional Physiological Phenomena; P | 1988 |
Aminophylline and gentamicin-2.
Topics: Administration, Oral; Aminophylline; Animals; Asthma; Dogs; Gentamicins; Humans; Injections, Intrape | 1986 |
Depressed plasma pyridoxal phosphate concentrations in adult asthmatics.
Topics: Adult; Aged; Asthma; Erythrocytes; Female; Humans; Male; Middle Aged; Plasma; Pyridoxal Phosphate; P | 1985 |