pyridoxal phosphate has been researched along with Arthritis, Rheumatoid in 11 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to determine if nonsupplementing older women (aged >or=55 years) with rheumatoid arthritis had higher plasma homocysteine and lower B-vitamin status compared to healthy controls." | 7.74 | Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis. ( Manore, MM; Woolf, K, 2008) |
| "The purpose of this study was to determine if nonsupplementing older women (aged >or=55 years) with rheumatoid arthritis had higher plasma homocysteine and lower B-vitamin status compared to healthy controls." | 3.74 | Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis. ( Manore, MM; Woolf, K, 2008) |
| "Patients with rheumatoid arthritis were found to have low plasma pyridoxal phosphate." | 3.65 | Vitamin B6 levels in rheumatoid arthritis: effect of treatment. ( Bernhart, FW; György, P; Schumacher, HR, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sande, JS | 1 |
| Ulvik, A | 1 |
| Midttun, Ø | 1 |
| Ueland, PM | 1 |
| Hammer, HB | 1 |
| Valen, M | 1 |
| Apalset, EM | 1 |
| Gjesdal, CG | 1 |
| Chang, HY | 1 |
| Tang, FY | 1 |
| Chen, DY | 1 |
| Chih, HM | 1 |
| Huang, ST | 1 |
| Cheng, HD | 1 |
| Lan, JL | 1 |
| Chiang, EP | 2 |
| Huang, SC | 2 |
| Wei, JC | 2 |
| Wu, DJ | 2 |
| Huang, YC | 2 |
| Lin, PT | 1 |
| Bekpinar, S | 1 |
| Koçak, H | 1 |
| Unlüçerçi, Y | 1 |
| Genç, S | 1 |
| Akdağ-Köse, A | 1 |
| Göğüş, F | 1 |
| Bagley, PJ | 1 |
| Roubenoff, R | 2 |
| Nadeau, M | 1 |
| Selhub, J | 2 |
| Woolf, K | 1 |
| Manore, MM | 1 |
| Roubenoff, RA | 1 |
| Nadeau, MR | 1 |
| Cannon, JG | 1 |
| Freeman, LM | 1 |
| Dinarello, CA | 1 |
| Rosenberg, IH | 1 |
| Schumacher, HR | 1 |
| Bernhart, FW | 1 |
| György, P | 1 |
| Bruckner, FE | 1 |
| Smith, HG | 1 |
| Lakatos, C | 1 |
| Chamberlain, MA | 1 |
| Anderson, BB | 1 |
| Peart, MB | 1 |
| Fulford-Jones, CE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00944866] | 30 participants (Anticipated) | Observational | 2008-03-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for pyridoxal phosphate and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Clinical use of cyclooxygenase inhibitors impairs vitamin B-6 metabolism.
Topics: Animals; Arthritis, Rheumatoid; Celecoxib; Cricetinae; Cross-Sectional Studies; Cyclooxygenase Inhib | 2013 |
Vitamin B(6) supplementation improves pro-inflammatory responses in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; B-Lymphocytes; Biomarkers; C-Reactive Protein; Cytokines; Dietary Supplements | 2010 |
The evaluation of C-reactive protein, homocysteine and vitamin B6 concentrations in Behçet and rheumatoid arthritis disease.
Topics: Adult; Arthritis, Rheumatoid; Behcet Syndrome; C-Reactive Protein; Female; Homocysteine; Humans; Mal | 2003 |
8 other studies available for pyridoxal phosphate and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Vitamin B-6 Status Correlates with Disease Activity in Rheumatoid Arthritis Patients During Treatment with TNFα Inhibitors.
Topics: Adult; Arthritis, Rheumatoid; Biomarkers; C-Reactive Protein; Female; Humans; Kynurenine; Longitudin | 2019 |
Plasma pyridoxal 5'-phosphate is not associated with inflammatory and immune responses after adjusting for serum albumin in patients with rheumatoid arthritis: a preliminary study.
Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthralgia; Arthritis, Rh | 2012 |
Plasma pyridoxal 5'-phosphate concentration is correlated with functional vitamin B-6 indices in patients with rheumatoid arthritis and marginal vitamin B-6 status.
Topics: Adult; Arthritis, Rheumatoid; Aspartate Aminotransferases; Case-Control Studies; Cross-Sectional Stu | 2003 |
Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cros | 2008 |
Abnormal vitamin B6 status in rheumatoid cachexia. Association with spontaneous tumor necrosis factor alpha production and markers of inflammation.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cachexia; Cross-Sectional Studies; Diet; Endotoxins; Female; Fol | 1995 |
Vitamin B6 levels in rheumatoid arthritis: effect of treatment.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Dose-Response Relationship, Drug; Female; H | 1975 |
Tryptophan metabolism in rheumatoid neuropathies.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Child; Child, Pres | 1972 |
The measurement of serum pyridoxal by a microbiological assay using Lactobacillus casei.
Topics: Adolescent; Adult; Age Factors; Aged; Anemia, Sideroblastic; Arthritis, Rheumatoid; Biological Assay | 1970 |