Page last updated: 2024-10-20

pyridoxal phosphate and Anemia, Sickle Cell

pyridoxal phosphate has been researched along with Anemia, Sickle Cell in 10 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Samarron, SL1
Miller, JW1
Cheung, AT1
Chen, PC1
Lin, X1
Zwerdling, T1
Wun, T1
Green, R1
Chao, TL2
Berenfeld, MR2
Gabuzda, TG1
Kark, JA2
Tarassoff, PG2
Bongiovanni, R2
Hicks, CU1
Hannah, JS1
Yoshida, GY1
Flores, L1
Pais, R1
Buchanan, I1
Arnelle, D1
Camp, VM1
Kutner, M1
Faraj, BA1
Eckman, J1
Ragab, A1
Adelekan, DA1
Adekile, AD1
Thurnham, DI1
Paniker, NV2
Ben-Bassat, I1
Beutler, E2
Benesch, R1
Benesch, RE1
Yung, S1
West, CJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Homocysteine in Myocardial Infarction Patients in a Tertiary Care Hospital of Twin Cities of Pakistan[NCT05011032]0 participants (Actual)Interventional2021-08-12Withdrawn (stopped due to Ethical approval was not done. Hence the funding was withhold.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

10 other studies available for pyridoxal phosphate and Anemia, Sickle Cell

ArticleYear
Homocysteine is associated with severity of microvasculopathy in sickle cell disease patients.
    British journal of haematology, 2020, Volume: 190, Issue:3

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Creatine; Folic Acid; Homocysteine;

2020
Protection of erythrocyte membrane amino groups from reaction with methyl acetimidate by pyridoxal 5'-phosphate Schiff base formation.
    Biochimica et biophysica acta, 1984, Apr-11, Volume: 771, Issue:2

    Topics: Anemia, Sickle Cell; Carbon Radioisotopes; Erythrocyte Membrane; Humans; Imidoesters; Indicators and

1984
Pyridoxal phosphate as an antisickling agent in vitro.
    The Journal of clinical investigation, 1983, Volume: 71, Issue:5

    Topics: Anemia, Sickle Cell; Dose-Response Relationship, Drug; Erythrocytes; Hemoglobin C Disease; Humans; O

1983
Modification of intracellular hemoglobin with pyridoxal and pyridoxal 5'-phosphate.
    Blood cells, 1982, Volume: 8, Issue:2

    Topics: Anemia, Sickle Cell; Binding, Competitive; Erythrocytes, Abnormal; Hemoglobin A; Hemoglobin, Sickle;

1982
Prevention of the immune agglutination of methyl acetimidate-reacted sickle erythrocytes by prior reaction with pyridoxal 5'-phosphate.
    The Journal of biological chemistry, 1981, Jun-10, Volume: 256, Issue:11

    Topics: Anemia, Sickle Cell; Erythrocyte Membrane; Erythrocytes; Hemagglutination; Humans; Imidoesters; Indi

1981
Pyridoxal 5'-phosphate levels in children with sickle cell disease.
    The American journal of pediatric hematology/oncology, 1988,Fall, Volume: 10, Issue:3

    Topics: Adolescent; Anemia, Sickle Cell; Black People; Child; Child, Preschool; Hemoglobins; Humans; Infant;

1988
Dependence of pyridoxine metabolism on riboflavin status in sickle cell patients.
    The American journal of clinical nutrition, 1987, Volume: 46, Issue:1

    Topics: Adolescent; Anemia, Sickle Cell; Aspartate Aminotransferases; Child; Child, Preschool; Erythrocytes;

1987
Evaluation of sickle hemoglobin and desickling agents by falling ball viscometry.
    The Journal of laboratory and clinical medicine, 1972, Volume: 80, Issue:2

    Topics: 6-Phytase; Anemia, Sickle Cell; Aspirin; Blood Viscosity; Carbamates; Cyanates; Drug Storage; Fructo

1972
Chemical modifications that inhibit gelation of sickle hemoglobin.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:4

    Topics: Amino Acid Sequence; Anemia, Sickle Cell; Chemical Phenomena; Chemistry; Chromatography, Gel; Gels;

1974
Pyridoxine administration in sickle cell disease: an unsuccessful attempt to influence the properties of sickle hemoglobin.
    Biochemical medicine, 1972, Volume: 6, Issue:2

    Topics: Anemia, Sickle Cell; Aspartate Aminotransferases; Blood Viscosity; Chromium Isotopes; Erythrocytes;

1972