pyridoxal phosphate has been researched along with Anemia, Sickle Cell in 10 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Samarron, SL | 1 |
| Miller, JW | 1 |
| Cheung, AT | 1 |
| Chen, PC | 1 |
| Lin, X | 1 |
| Zwerdling, T | 1 |
| Wun, T | 1 |
| Green, R | 1 |
| Chao, TL | 2 |
| Berenfeld, MR | 2 |
| Gabuzda, TG | 1 |
| Kark, JA | 2 |
| Tarassoff, PG | 2 |
| Bongiovanni, R | 2 |
| Hicks, CU | 1 |
| Hannah, JS | 1 |
| Yoshida, GY | 1 |
| Flores, L | 1 |
| Pais, R | 1 |
| Buchanan, I | 1 |
| Arnelle, D | 1 |
| Camp, VM | 1 |
| Kutner, M | 1 |
| Faraj, BA | 1 |
| Eckman, J | 1 |
| Ragab, A | 1 |
| Adelekan, DA | 1 |
| Adekile, AD | 1 |
| Thurnham, DI | 1 |
| Paniker, NV | 2 |
| Ben-Bassat, I | 1 |
| Beutler, E | 2 |
| Benesch, R | 1 |
| Benesch, RE | 1 |
| Yung, S | 1 |
| West, CJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Homocysteine in Myocardial Infarction Patients in a Tertiary Care Hospital of Twin Cities of Pakistan[NCT05011032] | 0 participants (Actual) | Interventional | 2021-08-12 | Withdrawn (stopped due to Ethical approval was not done. Hence the funding was withhold.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 other studies available for pyridoxal phosphate and Anemia, Sickle Cell
| Article | Year |
|---|---|
Homocysteine is associated with severity of microvasculopathy in sickle cell disease patients.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Creatine; Folic Acid; Homocysteine; | 2020 |
Protection of erythrocyte membrane amino groups from reaction with methyl acetimidate by pyridoxal 5'-phosphate Schiff base formation.
Topics: Anemia, Sickle Cell; Carbon Radioisotopes; Erythrocyte Membrane; Humans; Imidoesters; Indicators and | 1984 |
Pyridoxal phosphate as an antisickling agent in vitro.
Topics: Anemia, Sickle Cell; Dose-Response Relationship, Drug; Erythrocytes; Hemoglobin C Disease; Humans; O | 1983 |
Modification of intracellular hemoglobin with pyridoxal and pyridoxal 5'-phosphate.
Topics: Anemia, Sickle Cell; Binding, Competitive; Erythrocytes, Abnormal; Hemoglobin A; Hemoglobin, Sickle; | 1982 |
Prevention of the immune agglutination of methyl acetimidate-reacted sickle erythrocytes by prior reaction with pyridoxal 5'-phosphate.
Topics: Anemia, Sickle Cell; Erythrocyte Membrane; Erythrocytes; Hemagglutination; Humans; Imidoesters; Indi | 1981 |
Pyridoxal 5'-phosphate levels in children with sickle cell disease.
Topics: Adolescent; Anemia, Sickle Cell; Black People; Child; Child, Preschool; Hemoglobins; Humans; Infant; | 1988 |
Dependence of pyridoxine metabolism on riboflavin status in sickle cell patients.
Topics: Adolescent; Anemia, Sickle Cell; Aspartate Aminotransferases; Child; Child, Preschool; Erythrocytes; | 1987 |
Evaluation of sickle hemoglobin and desickling agents by falling ball viscometry.
Topics: 6-Phytase; Anemia, Sickle Cell; Aspirin; Blood Viscosity; Carbamates; Cyanates; Drug Storage; Fructo | 1972 |
Chemical modifications that inhibit gelation of sickle hemoglobin.
Topics: Amino Acid Sequence; Anemia, Sickle Cell; Chemical Phenomena; Chemistry; Chromatography, Gel; Gels; | 1974 |
Pyridoxine administration in sickle cell disease: an unsuccessful attempt to influence the properties of sickle hemoglobin.
Topics: Anemia, Sickle Cell; Aspartate Aminotransferases; Blood Viscosity; Chromium Isotopes; Erythrocytes; | 1972 |