pyridoxal phosphate has been researched along with Alloxan Diabetes in 16 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Excerpt | Relevance | Reference |
---|---|---|
"The rats were fed a vitamin B6-free diet and administered an equivalent amount of pyridoxine based on body weight." | 3.70 | Effect of diabetes on vitamin B6 requirement in experimental animals. ( Murakami, Y; Okada, M; Shibuya, M; Yamamoto, E, 1999) |
"Painful diabetic neuropathy causes hyperalgesia and does not respond to commonly used analgesics such as non-steroidal anti-inflammatory drugs or opioids at doses below those producing disruptive side effects." | 1.35 | Modulation of P2X receptors in dorsal root ganglion neurons of streptozotocin-induced diabetic neuropathy. ( Honda, K; Katsuragi, T; Koguchi, M; Migita, K; Moriyama, T; Takano, Y; Ueno, S, 2009) |
"Glycogen phosphorylase was determined measuring the pyridoxal-5' -phosphate content and using polyacrylamide gel electrophoresis." | 1.31 | The content of glycogen phosphorylase and glycogen in preparations of sarcoplasmic reticulum-glycogenolytic complex is enhanced in diabetic rat skeletal muscle. ( Garduño, E; Gutiérrez-Merino, C; Henao, F; Merino, JM; Nogues, M, 2001) |
"Triamcinolone treatment also lessened the inhibition of glucose-6-phosphatase by pyridoxal 5'-phosphate (PLP), but this effect was not due to an interaction of PLP with the active site." | 1.30 | Evidence that the transit of glucose into liver microsomes is not required for functional glucose-6-phosphatase. ( Annabi, B; van de Werve, G, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (31.25) | 18.7374 |
1990's | 3 (18.75) | 18.2507 |
2000's | 5 (31.25) | 29.6817 |
2010's | 3 (18.75) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Erion, DM | 1 |
Kotas, ME | 1 |
McGlashon, J | 1 |
Yonemitsu, S | 1 |
Hsiao, JJ | 1 |
Nagai, Y | 1 |
Iwasaki, T | 1 |
Murray, SF | 1 |
Bhanot, S | 1 |
Cline, GW | 1 |
Samuel, VT | 1 |
Shulman, GI | 1 |
Gillum, MP | 1 |
Liu, H | 1 |
Tang, J | 1 |
Lee, CA | 1 |
Kern, TS | 1 |
Migita, K | 1 |
Moriyama, T | 1 |
Koguchi, M | 1 |
Honda, K | 1 |
Katsuragi, T | 1 |
Takano, Y | 1 |
Ueno, S | 1 |
Kiran, SG | 1 |
Dorisetty, RK | 1 |
Umrani, MR | 1 |
Boindala, S | 1 |
Bhonde, RR | 1 |
Chalsani, M | 1 |
Singh, H | 1 |
Venkatesan, V | 1 |
FASELLA, P | 1 |
BAGLIONI, C | 1 |
TURANO, C | 1 |
SILIPRANDI, N | 1 |
Higuchi, O | 1 |
Nakagawa, K | 1 |
Tsuzuki, T | 1 |
Suzuki, T | 1 |
Oikawa, S | 1 |
Miyazawa, T | 1 |
Yamagishi, S | 1 |
Matsui, T | 1 |
Nakamura, K | 1 |
Yoshida, T | 1 |
Takeuchi, M | 1 |
Inoue, H | 2 |
Yoshida, Y | 1 |
Imaizumi, T | 1 |
Rahbar, S | 1 |
Weimbs, T | 1 |
Stoffel, W | 1 |
Annabi, B | 1 |
van de Werve, G | 1 |
Okada, M | 1 |
Shibuya, M | 1 |
Yamamoto, E | 1 |
Murakami, Y | 1 |
Garduño, E | 1 |
Nogues, M | 1 |
Merino, JM | 1 |
Gutiérrez-Merino, C | 1 |
Henao, F | 1 |
Hata, K | 1 |
Kikuchi, K | 1 |
Tada, K | 1 |
Tsuiki, S | 1 |
Rogers, KS | 1 |
Higgins, ES | 1 |
Kline, ES | 1 |
Kasper, CB | 1 |
Pitot, HC | 1 |
Yamada, K | 1 |
16 other studies available for pyridoxal phosphate and Alloxan Diabetes
Article | Year |
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cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) promotes glucagon clearance and hepatic amino acid catabolism to regulate glucose homeostasis.
Topics: Amino Acids; Animals; Antibodies, Neutralizing; Diabetes Mellitus, Experimental; Gene Knockdown Tech | 2013 |
Metanx and early stages of diabetic retinopathy.
Topics: Animals; Contrast Sensitivity; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Folic Acid; I- | 2015 |
Modulation of P2X receptors in dorsal root ganglion neurons of streptozotocin-induced diabetic neuropathy.
Topics: Adenosine Triphosphate; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Mod | 2009 |
Pyridoxal 5' phosphate protects islets against streptozotocin-induced beta-cell dysfunction--in vitro and in vivo.
Topics: Animals; Base Sequence; Diabetes Mellitus, Experimental; DNA Primers; In Vitro Techniques; Insulin; | 2011 |
Pyridoxal phosphate and tryptophan metabolism in alloxan-diabetic rats.
Topics: Alloxan; Animals; Coenzymes; Diabetes Mellitus, Experimental; Pyridoxal Phosphate; Rats; Tryptophan | 1960 |
Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5'-phosphate as the inhibitor.
Topics: Adult; Animals; Cholesterol; Diabetes Mellitus, Experimental; Diet; Glycolipids; Glycosylation; Huma | 2006 |
Pigment-epithelium-derived factor suppresses expression of receptor for advanced glycation end products in the eye of diabetic rats.
Topics: Adult; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; DNA Primers; | 2007 |
Novel inhibitors of glycation and AGE formation.
Topics: Animals; Ascorbic Acid; Body Weight; Butyrates; Cholesterol; Creatinine; Diabetes Mellitus, Experime | 2007 |
Topology of CNS myelin proteolipid protein: evidence for the nonenzymatic glycosylation of extracytoplasmic domains in normal and diabetic animals.
Topics: Amino Acid Sequence; Animals; Binding Sites; Borohydrides; Brain; Cattle; Cytoplasm; Diabetes Mellit | 1994 |
Evidence that the transit of glucose into liver microsomes is not required for functional glucose-6-phosphatase.
Topics: Animals; Biological Transport; Blotting, Northern; Borohydrides; Cholic Acids; Detergents; Diabetes | 1997 |
Effect of diabetes on vitamin B6 requirement in experimental animals.
Topics: Animals; Aspartate Aminotransferases; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; K | 1999 |
The content of glycogen phosphorylase and glycogen in preparations of sarcoplasmic reticulum-glycogenolytic complex is enhanced in diabetic rat skeletal muscle.
Topics: Animals; Blood Glucose; Calcium-Transporting ATPases; Diabetes Mellitus, Experimental; Glycogen; Gly | 2001 |
Analysis of glucose-6-phosphate translocase and hexose-6-phosphate phosphohydrolase, the two obligatory components of microsomal glucose-6-phosphatase system, in rat liver.
Topics: Aging; Animals; Animals, Newborn; Antiporters; Diabetes Mellitus, Experimental; Fetus; Glucose-6-Pho | 1988 |
Experimental diabetes causes mitochondrial loss and cytoplasmic enrichment of pyridoxal phosphate and aspartate aminotransferase activity.
Topics: Animals; Aspartate Aminotransferases; Cytoplasm; Diabetes Mellitus, Experimental; Electrophoresis, A | 1986 |
Studies on the induction and repression of enzymes in rat liver. VI. Some properties and the metabolic regulation of two isozymic forms of serine dehydratase.
Topics: Adrenal Glands; Adrenalectomy; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Chr | 1971 |
[Diabetes and vitamins].
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dogs; Humans; Pyridoxal Phosphate; Rats | 1967 |