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pyridoxal phosphate and Alloxan Diabetes

pyridoxal phosphate has been researched along with Alloxan Diabetes in 16 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Research Excerpts

ExcerptRelevanceReference
"The rats were fed a vitamin B6-free diet and administered an equivalent amount of pyridoxine based on body weight."3.70Effect of diabetes on vitamin B6 requirement in experimental animals. ( Murakami, Y; Okada, M; Shibuya, M; Yamamoto, E, 1999)
"Painful diabetic neuropathy causes hyperalgesia and does not respond to commonly used analgesics such as non-steroidal anti-inflammatory drugs or opioids at doses below those producing disruptive side effects."1.35Modulation of P2X receptors in dorsal root ganglion neurons of streptozotocin-induced diabetic neuropathy. ( Honda, K; Katsuragi, T; Koguchi, M; Migita, K; Moriyama, T; Takano, Y; Ueno, S, 2009)
"Glycogen phosphorylase was determined measuring the pyridoxal-5' -phosphate content and using polyacrylamide gel electrophoresis."1.31The content of glycogen phosphorylase and glycogen in preparations of sarcoplasmic reticulum-glycogenolytic complex is enhanced in diabetic rat skeletal muscle. ( Garduño, E; Gutiérrez-Merino, C; Henao, F; Merino, JM; Nogues, M, 2001)
"Triamcinolone treatment also lessened the inhibition of glucose-6-phosphatase by pyridoxal 5'-phosphate (PLP), but this effect was not due to an interaction of PLP with the active site."1.30Evidence that the transit of glucose into liver microsomes is not required for functional glucose-6-phosphatase. ( Annabi, B; van de Werve, G, 1997)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's3 (18.75)18.2507
2000's5 (31.25)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erion, DM1
Kotas, ME1
McGlashon, J1
Yonemitsu, S1
Hsiao, JJ1
Nagai, Y1
Iwasaki, T1
Murray, SF1
Bhanot, S1
Cline, GW1
Samuel, VT1
Shulman, GI1
Gillum, MP1
Liu, H1
Tang, J1
Lee, CA1
Kern, TS1
Migita, K1
Moriyama, T1
Koguchi, M1
Honda, K1
Katsuragi, T1
Takano, Y1
Ueno, S1
Kiran, SG1
Dorisetty, RK1
Umrani, MR1
Boindala, S1
Bhonde, RR1
Chalsani, M1
Singh, H1
Venkatesan, V1
FASELLA, P1
BAGLIONI, C1
TURANO, C1
SILIPRANDI, N1
Higuchi, O1
Nakagawa, K1
Tsuzuki, T1
Suzuki, T1
Oikawa, S1
Miyazawa, T1
Yamagishi, S1
Matsui, T1
Nakamura, K1
Yoshida, T1
Takeuchi, M1
Inoue, H2
Yoshida, Y1
Imaizumi, T1
Rahbar, S1
Weimbs, T1
Stoffel, W1
Annabi, B1
van de Werve, G1
Okada, M1
Shibuya, M1
Yamamoto, E1
Murakami, Y1
Garduño, E1
Nogues, M1
Merino, JM1
Gutiérrez-Merino, C1
Henao, F1
Hata, K1
Kikuchi, K1
Tada, K1
Tsuiki, S1
Rogers, KS1
Higgins, ES1
Kline, ES1
Kasper, CB1
Pitot, HC1
Yamada, K1

Other Studies

16 other studies available for pyridoxal phosphate and Alloxan Diabetes

ArticleYear
cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) promotes glucagon clearance and hepatic amino acid catabolism to regulate glucose homeostasis.
    The Journal of biological chemistry, 2013, May-31, Volume: 288, Issue:22

    Topics: Amino Acids; Animals; Antibodies, Neutralizing; Diabetes Mellitus, Experimental; Gene Knockdown Tech

2013
Metanx and early stages of diabetic retinopathy.
    Investigative ophthalmology & visual science, 2015, Jan-08, Volume: 56, Issue:1

    Topics: Animals; Contrast Sensitivity; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Folic Acid; I-

2015
Modulation of P2X receptors in dorsal root ganglion neurons of streptozotocin-induced diabetic neuropathy.
    Neuroscience letters, 2009, Mar-13, Volume: 452, Issue:2

    Topics: Adenosine Triphosphate; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Mod

2009
Pyridoxal 5' phosphate protects islets against streptozotocin-induced beta-cell dysfunction--in vitro and in vivo.
    Experimental biology and medicine (Maywood, N.J.), 2011, Apr-01, Volume: 236, Issue:4

    Topics: Animals; Base Sequence; Diabetes Mellitus, Experimental; DNA Primers; In Vitro Techniques; Insulin;

2011
Pyridoxal phosphate and tryptophan metabolism in alloxan-diabetic rats.
    Clinica chimica acta; international journal of clinical chemistry, 1960, Volume: 5

    Topics: Alloxan; Animals; Coenzymes; Diabetes Mellitus, Experimental; Pyridoxal Phosphate; Rats; Tryptophan

1960
Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5'-phosphate as the inhibitor.
    Journal of lipid research, 2006, Volume: 47, Issue:5

    Topics: Adult; Animals; Cholesterol; Diabetes Mellitus, Experimental; Diet; Glycolipids; Glycosylation; Huma

2006
Pigment-epithelium-derived factor suppresses expression of receptor for advanced glycation end products in the eye of diabetic rats.
    Ophthalmic research, 2007, Volume: 39, Issue:2

    Topics: Adult; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; DNA Primers;

2007
Novel inhibitors of glycation and AGE formation.
    Cell biochemistry and biophysics, 2007, Volume: 48, Issue:2-3

    Topics: Animals; Ascorbic Acid; Body Weight; Butyrates; Cholesterol; Creatinine; Diabetes Mellitus, Experime

2007
Topology of CNS myelin proteolipid protein: evidence for the nonenzymatic glycosylation of extracytoplasmic domains in normal and diabetic animals.
    Biochemistry, 1994, Aug-30, Volume: 33, Issue:34

    Topics: Amino Acid Sequence; Animals; Binding Sites; Borohydrides; Brain; Cattle; Cytoplasm; Diabetes Mellit

1994
Evidence that the transit of glucose into liver microsomes is not required for functional glucose-6-phosphatase.
    Biochemical and biophysical research communications, 1997, Jul-30, Volume: 236, Issue:3

    Topics: Animals; Biological Transport; Blotting, Northern; Borohydrides; Cholic Acids; Detergents; Diabetes

1997
Effect of diabetes on vitamin B6 requirement in experimental animals.
    Diabetes, obesity & metabolism, 1999, Volume: 1, Issue:4

    Topics: Animals; Aspartate Aminotransferases; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; K

1999
The content of glycogen phosphorylase and glycogen in preparations of sarcoplasmic reticulum-glycogenolytic complex is enhanced in diabetic rat skeletal muscle.
    Diabetologia, 2001, Volume: 44, Issue:10

    Topics: Animals; Blood Glucose; Calcium-Transporting ATPases; Diabetes Mellitus, Experimental; Glycogen; Gly

2001
Analysis of glucose-6-phosphate translocase and hexose-6-phosphate phosphohydrolase, the two obligatory components of microsomal glucose-6-phosphatase system, in rat liver.
    The Tohoku journal of experimental medicine, 1988, Volume: 155, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Antiporters; Diabetes Mellitus, Experimental; Fetus; Glucose-6-Pho

1988
Experimental diabetes causes mitochondrial loss and cytoplasmic enrichment of pyridoxal phosphate and aspartate aminotransferase activity.
    Biochemical medicine and metabolic biology, 1986, Volume: 36, Issue:1

    Topics: Animals; Aspartate Aminotransferases; Cytoplasm; Diabetes Mellitus, Experimental; Electrophoresis, A

1986
Studies on the induction and repression of enzymes in rat liver. VI. Some properties and the metabolic regulation of two isozymic forms of serine dehydratase.
    The Journal of biological chemistry, 1971, Apr-25, Volume: 246, Issue:8

    Topics: Adrenal Glands; Adrenalectomy; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Chr

1971
[Diabetes and vitamins].
    Nihon Ishikai zasshi. Journal of the Japan Medical Association, 1967, Nov-15, Volume: 58, Issue:10

    Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dogs; Humans; Pyridoxal Phosphate; Rats

1967