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pyridoxal phosphate and Alcoholic Hepatitis

pyridoxal phosphate has been researched along with Alcoholic Hepatitis in 4 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Research Excerpts

ExcerptRelevanceReference
"To determine the pharmacokinetic (PK) profile of manganese (Mn) after a 2-hour intravenous infusion of mangafodipir at 5 micromol/kg body weight and to correlate Mn concentrations with oxidative stress, early decrease in serum total bilirubin concentration, and prothrombin time (PT) in chronic alcoholic patients with acute alcoholic hepatitis."9.14Pharmacokinetic-pharmacodynamic modeling of manganese after a single intravenous infusion of mangafodipir in patients with acute alcoholic hepatitis. ( Batteux, F; Debray, M; Hirt, D; Laurent, A; Pavlovic, S; Poupon, J; Richardet, JP; Sogni, P; Treluyer, JM; Urien, S; Weill, B, 2009)
"To determine the pharmacokinetic (PK) profile of manganese (Mn) after a 2-hour intravenous infusion of mangafodipir at 5 micromol/kg body weight and to correlate Mn concentrations with oxidative stress, early decrease in serum total bilirubin concentration, and prothrombin time (PT) in chronic alcoholic patients with acute alcoholic hepatitis."5.14Pharmacokinetic-pharmacodynamic modeling of manganese after a single intravenous infusion of mangafodipir in patients with acute alcoholic hepatitis. ( Batteux, F; Debray, M; Hirt, D; Laurent, A; Pavlovic, S; Poupon, J; Richardet, JP; Sogni, P; Treluyer, JM; Urien, S; Weill, B, 2009)
"The relationship between pyridoxal phosphate deficiency and activities of serum and liver aminotransferases was studied in 12 patients with alcoholic hepatitis."3.67Relationship between pyridoxal 5'-phosphate deficiency and aminotransferase levels in alcoholic hepatitis. ( Boitnott, J; Diehl, AM; Herlong, HF; Mezey, E; Potter, J; Van Duyn, MA, 1984)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirt, D1
Richardet, JP1
Urien, S1
Poupon, J1
Sogni, P1
Batteux, F1
Laurent, A1
Pavlovic, S1
Debray, M1
Treluyer, JM1
Weill, B1
Diehl, AM2
Potter, J1
Boitnott, J1
Van Duyn, MA1
Herlong, HF2
Mezey, E2
Kakuma, S1
Leevy, CM1
Frank, O1
Baker, H1
Mitchell, MC1
Potter, JJ1
Wacker, L1

Trials

1 trial available for pyridoxal phosphate and Alcoholic Hepatitis

ArticleYear
Pharmacokinetic-pharmacodynamic modeling of manganese after a single intravenous infusion of mangafodipir in patients with acute alcoholic hepatitis.
    Therapeutic drug monitoring, 2009, Volume: 31, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Anesthetics, Local; Antineoplastic Combined Chemotherapy Pro

2009

Other Studies

3 other studies available for pyridoxal phosphate and Alcoholic Hepatitis

ArticleYear
Relationship between pyridoxal 5'-phosphate deficiency and aminotransferase levels in alcoholic hepatitis.
    Gastroenterology, 1984, Volume: 86, Issue:4

    Topics: Acute Disease; Adult; Alanine Transaminase; Aspartate Aminotransferases; Female; Hepatitis, Alcoholi

1984
Protection of pyridoxal 5'-phosphate against toxicity of acetaldehyde to hepatocytes.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1981, Volume: 168, Issue:3

    Topics: Acetaldehyde; Benzylamines; Cell Survival; Hepatitis, Alcoholic; Humans; In Vitro Techniques; Liver;

1981
Changes in plasma amino acids during sobriety in alcoholic patients with and without liver disease.
    The American journal of clinical nutrition, 1986, Volume: 44, Issue:4

    Topics: Alcoholism; Amino Acids; Dietary Proteins; Energy Intake; Hepatitis, Alcoholic; Humans; Liver; Pyrid

1986