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pyridoxal phosphate and Alcohol Abuse

pyridoxal phosphate has been researched along with Alcohol Abuse in 24 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Research Excerpts

ExcerptRelevanceReference
"The plasma pyridoxal-5'-phosphate (PLP) level of alcoholic subjects has been compared with that of non-alcoholic individuals in order to ascertain the incidence of abnormal vitamin B(6) metabolism in chronic alcohol abuse."7.65Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes. ( Li, TK; Lumeng, L, 1974)
"The plasma pyridoxal-5'-phosphate (PLP) level of alcoholic subjects has been compared with that of non-alcoholic individuals in order to ascertain the incidence of abnormal vitamin B(6) metabolism in chronic alcohol abuse."3.65Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes. ( Li, TK; Lumeng, L, 1974)
"Body weight was under 90% of the ideal in 8/33 (24%) patients."1.30Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption. ( Camilo, ME; Cardoso, JN; Cravo, M; Glória, L; Leitão, CN; Mira, FC; Oliveira, AG; Resende, M, 1997)
"The results indicate that in man, alcohol abuse is connected with reduced activities of several glycosyltransferases in serum, which may reflect an important mechanism behind the carbohydrate deficiencies in secretory as well as membrane-bound glyconjugates in alcoholic patients."1.28Glycoprotein glycosyltransferase activities in serum in alcohol-abusing patients and healthy controls. ( Borg, S; Stibler, H, 1991)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199021 (87.50)18.7374
1990's3 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
French, SW2
Castagna, J1
Bonjour, JP1
Heidemann, E1
Waller, HD1
Majumdar, SK2
Shaw, GK2
O'Gorman, P1
Aps, EJ1
Offerman, EL1
Thomson, AD2
Shane, B1
Fonda, ML2
Glória, L1
Cravo, M1
Camilo, ME1
Resende, M1
Cardoso, JN1
Oliveira, AG1
Leitão, CN1
Mira, FC1
Chillar, RK1
Johnson, CS1
Beutler, E1
Parker, TH1
Marshall, JP1
Roberts, RK1
Wang, S1
Schiff, ER1
Wilkinson, GR1
Schenker, S1
Labadarios, D2
Rossouw, JE2
McConnell, JB1
Davis, M2
Williams, R2
Pierce, HI1
McGuffin, RG1
Hillman, RS1
Hines, JD2
Stibler, H1
Borg, S1
Brown, SG1
Pendleton, MW1
Diehl, AM1
Mitchell, MC1
Herlong, HF1
Potter, JJ1
Wacker, L1
Mezey, E1
Chung, SH1
Caidan, SJ1
Norris, DK1
Lumeng, L1
Li, TK1
Cowan, DH1
Weintraub, LR1
Hamfelt, A1

Reviews

2 reviews available for pyridoxal phosphate and Alcohol Abuse

ArticleYear
Vitamins and alcoholism. III. Vitamin B6.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1980, Volume: 50, Issue:2

    Topics: Alcoholism; Anemia, Sideroblastic; Animals; Aspartate Aminotransferases; False Positive Reactions; F

1980
Pyridoxine and its metabolism in chronic liver disease.
    Nutrition reviews, 1977, Volume: 35, Issue:6

    Topics: Alcoholism; Chemical and Drug Induced Liver Injury; Chronic Disease; Humans; Liver; Liver Diseases;

1977

Other Studies

22 other studies available for pyridoxal phosphate and Alcohol Abuse

ArticleYear
Some effects of chronic ethanol feeding on vitamin B 6 deficiency in the rat.
    Laboratory investigation; a journal of technical methods and pathology, 1967, Volume: 16, Issue:4

    Topics: Acrodynia; Alanine Transaminase; Alcoholism; Animals; Biopsy; Body Weight; Carboxy-Lyases; Dopa Deca

1967
[Disorders of erythropoiesis and the immune system caused by alcohol. 1. Erythropoiesis].
    Fortschritte der Medizin, 1983, Sep-15, Volume: 101, Issue:35

    Topics: Acid Phosphatase; Alcoholism; Anemia; Bone Marrow Cells; Erythrocyte Indices; Erythropoiesis; Female

1983
Blood vitamin status (B1, B2, B6, folic acid and B12) in patients with alcoholic liver disease.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1982, Volume: 52, Issue:3

    Topics: Adult; Alcoholism; Folic Acid; Hepatitis; Humans; Liver Cirrhosis, Alcoholic; Liver Diseases; Middle

1982
Vitamin B-6 metabolism and turnover in the ethanol-fed rat.
    The Journal of nutrition, 1982, Volume: 112, Issue:4

    Topics: Alcoholism; Animals; Body Weight; Brain; Female; Humans; Liver; Male; Organ Size; Organophosphorus C

1982
Vitamin utilization status in chronic alcoholics.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1981, Volume: 51, Issue:1

    Topics: Adult; Aged; Alcoholism; Erythrocytes; Female; Glutathione Reductase; Humans; Male; Middle Aged; Pyr

1981
Vitamin B6 metabolism and binding to proteins in the blood of alcoholic and nonalcoholic men.
    Alcoholism, clinical and experimental research, 1993, Volume: 17, Issue:6

    Topics: Adult; Alcoholism; Aldehyde Oxidoreductases; Erythrocytes; Humans; Liver; Male; Phosphoric Monoester

1993
Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:3

    Topics: Adult; Alcohol Drinking; Alcoholism; Avitaminosis; Body Height; Body Mass Index; Body Weight; Diet;

1997
Erythrocyte pyridoxine kinase levels in patients with sideroblastic anemia.
    The New England journal of medicine, 1976, Oct-14, Volume: 295, Issue:16

    Topics: Alcoholic Intoxication; Alcoholism; Anemia, Sideroblastic; Aspartate Aminotransferases; Black People

1976
Effect of acute alcohol ingestion on plasma pyridoxal 5'-phosphate.
    The American journal of clinical nutrition, 1979, Volume: 32, Issue:6

    Topics: Alcoholism; Animals; Dogs; Dose-Response Relationship, Drug; Ethanol; Female; Humans; Kinetics; Male

1979
Vitamin B6 deficiency in chronic liver disease--evidence for increased degradation of pyridoxal-5'-phosphate.
    Gut, 1977, Volume: 18, Issue:1

    Topics: Alcoholism; Chronic Disease; Humans; Liver Diseases; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine

1977
Clinical studies in alcoholic sideroblastosis.
    Archives of internal medicine, 1976, Volume: 136, Issue:3

    Topics: Adult; Aged; Alcoholism; Anemia, Sideroblastic; Chronic Disease; Diet; Erythropoiesis; Ethanol; Foli

1976
Pyridoxine deficiency in severe liver disease [proceedings].
    The Proceedings of the Nutrition Society, 1976, Volume: 35, Issue:3

    Topics: Alcoholism; Ascorbic Acid; Ascorbic Acid Deficiency; Avitaminosis; Humans; Liver Cirrhosis; Pyridoxa

1976
Hematologic abnormalities involving vitamin B6 and folate metabolism in alcoholic subjects.
    Annals of the New York Academy of Sciences, 1975, Apr-25, Volume: 252

    Topics: Alcoholism; Chronic Disease; Diet Therapy; Enzyme Inhibitors; Erythrocytes; Ethanol; Female; Folic A

1975
Glycoprotein glycosyltransferase activities in serum in alcohol-abusing patients and healthy controls.
    Scandinavian journal of clinical and laboratory investigation, 1991, Volume: 51, Issue:1

    Topics: Acetaldehyde; Adult; Alcoholism; beta-D-Galactoside alpha 2-6-Sialyltransferase; Galactosyltransfera

1991
Concentration of vitamin B6 and activities of enzymes of B6 metabolism in the blood of alcoholic and nonalcoholic men.
    Alcoholism, clinical and experimental research, 1989, Volume: 13, Issue:6

    Topics: Adult; Alcoholism; Aldehyde Oxidoreductases; Chromatography, High Pressure Liquid; Erythrocytes; Hum

1989
Changes in plasma amino acids during sobriety in alcoholic patients with and without liver disease.
    The American journal of clinical nutrition, 1986, Volume: 44, Issue:4

    Topics: Alcoholism; Amino Acids; Dietary Proteins; Energy Intake; Hepatitis, Alcoholic; Humans; Liver; Pyrid

1986
Enhancement of brain pyridoxal 5'-phosphate level following chronic ingestion of ethanol.
    Neuroscience letters, 1985, Dec-04, Volume: 62, Issue:2

    Topics: Alcoholism; Animals; Behavior, Animal; Brain Chemistry; Disease Models, Animal; Ethanol; Female; Flu

1985
Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes.
    The Journal of clinical investigation, 1974, Volume: 53, Issue:3

    Topics: Acetaldehyde; Adolescent; Adult; Age Factors; Aged; Alcohol Oxidoreductases; Alcoholism; Erythrocyte

1974
Studies on the pathogenesis of alcohol-induced sideroblastic bone-marrow abnormalities.
    The New England journal of medicine, 1970, Aug-27, Volume: 283, Issue:9

    Topics: Adult; Alcoholism; Anemia, Sideroblastic; Bone Marrow; Bone Marrow Examination; Erythrocytes; Ethano

1970
The continuing saga of the sideroblast.
    The New England journal of medicine, 1970, Aug-27, Volume: 283, Issue:9

    Topics: Alcoholism; Anemia, Sideroblastic; Bone Marrow; Ethanol; Folic Acid Deficiency; Heme; Humans; Iron;

1970
Alcohol-induced vitamin-B 6-responsive anemia.
    The New England journal of medicine, 1970, Nov-19, Volume: 283, Issue:21

    Topics: Alcoholism; Anemia, Sideroblastic; Animals; Ethanol; Humans; Liver; Male; Phosphotransferases; Pyrid

1970
The effect of pyridoxal phosphate on the aminotransferase assay in blood.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1966, Volume: 18

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Erythrocytes

1966