Page last updated: 2024-10-20

pyridoxal phosphate and Aging

pyridoxal phosphate has been researched along with Aging in 59 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" We investigated the possible correlation between deficiency of vitamins B6, B12 or folic acid and hyperhomocysteinemia in Pakistani patients with acute myocardial infarction (AMI)."7.73Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction. ( Ali, SA; Iqbal, MP; Ishaq, M; Kazmi, KA; Khan, AH; Mehboobali, N; Waqar, MA; Yousuf, FA, 2005)
"It was shown the alterations in hydrogen sulfide (H(2)S) metabolism and the development of oxidative and nitrozative stress in cardiovascular system by aging."3.85[PYRIDOXAL-5-PHOSPHATE RESTORES HYDROGEN SULFIDE SYNTHES AND REDOX STATE OF HEART AND BLOOD VESSELS TISSUE IN OLD ANIMALS]. ( Budko, AY; Mys, LA; Sagach, VF; Strutynska, NA, 2017)
" We investigated the possible correlation between deficiency of vitamins B6, B12 or folic acid and hyperhomocysteinemia in Pakistani patients with acute myocardial infarction (AMI)."3.73Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction. ( Ali, SA; Iqbal, MP; Ishaq, M; Kazmi, KA; Khan, AH; Mehboobali, N; Waqar, MA; Yousuf, FA, 2005)
"Plasma tHcy, serum concentrations of pyridoxal-5-phosphate, vitamin B-12, and folate, intake of coffee and tea, alcohol, and methionine, as well as cigarette smoking, were determined in 252 elderly subjects (60-87 years old) of the longitudinal study on nutrition and health status in an aging population in Giessen (GISELA) and 99 young adults (20-34 years old) of the study on health and nutrition of young adults (GEJE)."3.72Effect of age on plasma homocysteine concentrations in young and elderly subjects considering serum vitamin concentrations and different lifestyle factors. ( Hartmann, B; Krems, C; Lührmann, PM; Neuhäuser-Berthold, M; Strassburg, A, 2004)
"Vitamin B-6 vitamer distribution and activities of vitamin B-6 metabolizing enzymes were evaluated in aging male and female Wistar rats fed a purified diet (containing 250 g of casein and 6 mg of pyridoxine hydrochloride per kg) from weaning until 31 mo of age."3.68Influence of age and sex on vitamin B-6 vitamer distribution and on vitamin B-6 metabolizing enzymes in Wistar rats. ( Bode, W; Mocking, JA; van den Berg, H, 1991)
"Eighteen children with West syndrome (5-11 months of age) were selected to receive an oral dose of pyridoxal phosphate, (20-50 mg/kg) for 14 d."2.69Cerebrospinal fluid somatostatin in West syndrome: changes in response to combined treatment with high-dose pyridoxal phosphate and low-dose corticotropin. ( Hirai, K; Seki, T; Takuma, Y, 1998)
"Patients with pressure sores have as part of their treatment been reefed with energy and proteins with varying result."1.31Reduced serum concentrations of riboflavine and ascorbic acid, and blood thiamine pyrophosphate and pyridoxal-5-phosphate in geriatric patients with and without pressure sores. ( Benkestock, K; Bøhmer, T; Selvaag, E, 2002)
"The odds ratio (OR) for severe coronary atherosclerosis (case status) for each 1 SD increase in fasting tHcy (5 micromol/L) was 1."1.30Plasma total homocysteine, B vitamins, and risk of coronary atherosclerosis. ( Grobbee, DE; Kok, FJ; Kruyssen, DA; Refsum, H; Schouten, EG; Ueland, PM; Verhoef, P; Witteman, JC, 1997)
" For direct assessment of how the bioavailability of vitamin B-6 is affected by aging, [2H]pyridoxine was orally administered to healthy men, aged 20-30 and 60-70 y, who were fed a controlled diet."1.29Bioavailability of vitamin B-6 in young and older men. ( Ferroli, CE; Trumbo, PR, 1994)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199029 (49.15)18.7374
1990's14 (23.73)18.2507
2000's10 (16.95)29.6817
2010's4 (6.78)24.3611
2020's2 (3.39)2.80

Authors

AuthorsStudies
Mys, L1
Goshovska, Y1
Strutynska, N1
Fedichkina, R1
Korkach, Y1
Strutynskyi, R1
Sagach, V1
Jungert, A1
McNulty, H2
Hoey, L2
Ward, M2
Strain, JJ2
Hughes, CF2
McAnena, L1
Neuhäuser-Berthold, M2
Pentieva, K1
Mys, LA1
Budko, AY1
Strutynska, NA1
Sagach, VF1
Moore, K1
Cunningham, C1
Molloy, AM1
McCarroll, K1
Casey, MC1
Tracey, F1
Laird, E1
O'Kane, M1
Ulvik, A1
Theofylaktopoulou, D1
Midttun, Ø1
Nygård, O1
Eussen, SJ1
Ueland, PM2
Fukuwatari, T1
Wada, H1
Shibata, K1
Jia, C1
Hegg, CC1
Pasantes-Morales, H1
Lopez-Colome, AM1
Salceda, R1
Mandel, P2
Uckermann, O1
Grosche, J1
Reichenbach, A1
Bringmann, A1
Strassburg, A1
Krems, C1
Lührmann, PM1
Hartmann, B1
Massé, PG1
Mahuren, JD1
Tranchant, C1
Dosy, J1
Iqbal, MP1
Ishaq, M1
Kazmi, KA1
Yousuf, FA1
Mehboobali, N1
Ali, SA1
Khan, AH1
Waqar, MA1
Anikina, TA1
Bilalova, GA1
Zverev, AA1
Sitdikov, FG1
Tyce, GM1
Wong, KL1
Szajnert, MF2
Beck, G1
Schapira, F2
Guilland, JC1
Bereksi-Reguig, B1
Lequeu, B1
Moreau, D1
Klepping, J1
Richard, D1
Hamfelt, A2
Soderhjelm, L1
Kittler, JM1
Viceps-Madore, D1
Cidlowski, JA1
Thanassi, JW1
Lacour, B1
Vassault, A1
Degos, F1
Bruneau, M1
Kreis, H1
Bailly, M1
Fonda, ML3
Eggers, DK3
Mehta, R2
Auerbach, S1
Fritsch, L1
Plebani, M1
Bonvicini, P1
De Besi, T1
Giordano, A1
Pesarin, F1
Ceriotti, G1
Heiskanen, K2
Kallio, M1
Salmenperä, L2
Siimes, MA2
Ruokonen, I1
Perheentupa, J2
Ferroli, CE1
Trumbo, PR1
Pannemans, DL1
van den Berg, H3
Westerterp, KR1
Selhub, J1
Jacques, PF1
Wilson, PW1
Rush, D1
Rosenberg, IH1
Chou, DK1
Jungalwala, FB1
Verhoef, P1
Kok, FJ1
Kruyssen, DA1
Schouten, EG1
Witteman, JC1
Grobbee, DE1
Refsum, H1
Hegde, SS1
Mandel, DA1
Wilford, MR1
Briaud, S1
Ford, AP1
Eglen, RM1
Hirai, K1
Seki, T1
Takuma, Y1
McKay, DL1
Perrone, G1
Rasmussen, H1
Dallal, G1
Blumberg, JB1
Matte, JJ1
Girard, CL1
Sève, B1
Selvaag, E1
Bøhmer, T1
Benkestock, K1
Bates, CJ1
Thane, CW1
Prentice, A1
Delves, HT1
Recasens, M1
Gabellec, MM1
Mack, G1
Bayomi, RA1
Smith, WR1
Andersson, A1
Brattström, L1
Israelsson, B1
Isaksson, A1
Hultberg, B1
Greif, KF1
Erlander, MG1
Tillakaratne, NJ1
Tobin, AJ1
Bode, W2
Mocking, JA1
Cochary, EF1
Gershoff, SN1
Sadowski, JA1
Trigun, SK1
Singh, SN1
Manore, MM1
Vaughan, LA1
Carroll, SS1
Leklem, JE1
Hata, K1
Kikuchi, K1
Tada, K1
Tsuiki, S1
Toledo, A1
Sabriá, J1
Rodriguez, R1
Brandner, R1
Rodriguez, J1
Palacios, JM1
Blanco, I1
Kant, AK1
Moser-Veillon, PB1
Reynolds, RD1
Morita, E1
Shirakami, Y1
Mizuno, N1
Nirmal Kumar, A1
Kalyankar, GD1
Fisher, SK1
Davies, WE1
Rinaudo, MT1
Bruno, R1
Ebadi, MS1
Lloyd, KG1
Hornykiewicz, O1
György, P1
Chabner, B1
Livingston, D1
Nery, R1
Gey, KF1
Burkard, WP1
Pletscher, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assesment of Vitamin B6 Level in Patients With Major Depressive Disorder[NCT05649293]94 participants (Anticipated)Observational2023-04-01Not yet recruiting
Effect of Polyvitaminics (Pyridoxine Hydrochloride, Folic Acid and Cyanocobalamin) in the Concentration of Homocysteine and Lipid Profile in Postmenopausal Women: a Randomized Controlled, Double-blind Clinical Trial[NCT03221816]Phase 460 participants (Actual)Interventional2008-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for pyridoxal phosphate and Aging

ArticleYear
Ontogenetic alterations of vitamin B 6 metabolism in rat brain--evidence of acceleration of its turnover rate.
    Advances in biochemical psychopharmacology, 1972, Volume: 4

    Topics: Aging; Animals; Animals, Newborn; Biodegradation, Environmental; Biotransformation; Brain; Brain Che

1972
Developments leading to the metabolic role of vitamin B 6.
    The American journal of clinical nutrition, 1971, Volume: 24, Issue:10

    Topics: Acrodynia; Adult; Aged; Aging; Amines; Animals; Arteriosclerosis; Aspartate Aminotransferases; Biolo

1971

Trials

4 trials available for pyridoxal phosphate and Aging

ArticleYear
Substrate product ratios of enzymes in the kynurenine pathway measured in plasma as indicators of functional vitamin B-6 status.
    The American journal of clinical nutrition, 2013, Volume: 98, Issue:4

    Topics: 3-Hydroxyanthranilic Acid; Aged; Aging; Biomarkers; Cross-Sectional Studies; Female; Humans; Hydrola

2013
The influence of protein intake on vitamin B-6 metabolism differs in young and elderly humans.
    The Journal of nutrition, 1994, Volume: 124, Issue:8

    Topics: Adult; Aged; Aging; Dietary Proteins; Energy Intake; Female; Humans; Male; Protein Biosynthesis; Pro

1994
Cerebrospinal fluid somatostatin in West syndrome: changes in response to combined treatment with high-dose pyridoxal phosphate and low-dose corticotropin.
    Neuropeptides, 1998, Volume: 32, Issue:6

    Topics: Adrenocorticotropic Hormone; Aging; Anti-Inflammatory Agents; Female; Humans; Infant; Male; Pyridoxa

1998
Multivitamin/mineral supplementation improves plasma B-vitamin status and homocysteine concentration in healthy older adults consuming a folate-fortified diet.
    The Journal of nutrition, 2000, Volume: 130, Issue:12

    Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cerebrovascular Disorders; Dietary Suppleme

2000

Other Studies

53 other studies available for pyridoxal phosphate and Aging

ArticleYear
Pyridoxal-5-phosphate induced cardioprotection in aging associated with up-expression of cystathionine-γ-lyase, 3-mercaptopyruvate sulfurtransferase, and ATP-sensitive potassium channels.
    European journal of clinical investigation, 2022, Volume: 52, Issue:2

    Topics: Aging; Animals; Cardiotonic Agents; Cystathionine gamma-Lyase; Gene Expression Regulation; Heart; KA

2022
Riboflavin Is an Important Determinant of Vitamin B-6 Status in Healthy Adults.
    The Journal of nutrition, 2020, 10-12, Volume: 150, Issue:10

    Topics: Adult; Aged; Aging; Diet; Humans; Life Style; Middle Aged; Pyridoxal Phosphate; Riboflavin; Vitamin

2020
[PYRIDOXAL-5-PHOSPHATE RESTORES HYDROGEN SULFIDE SYNTHES AND REDOX STATE OF HEART AND BLOOD VESSELS TISSUE IN OLD ANIMALS].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2017, Volume: 63, Issue:1

    Topics: Aging; Animals; Aorta; Cardiotonic Agents; Hydrogen Sulfide; Hydroxyl Radical; Leukotriene C4; Male;

2017
B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study.
    Journal of the American Medical Directors Association, 2019, Volume: 20, Issue:5

    Topics: Aged; Aging; Biomarkers; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Depression;

2019
Age-related alterations of B-group vitamin contents in urine, blood and liver from rats.
    Journal of nutritional science and vitaminology, 2008, Volume: 54, Issue:5

    Topics: Age Factors; Aging; Animals; Biotin; Body Weight; Eating; Folic Acid; Liver; Male; Models, Animal; N

2008
NPY mediates ATP-induced neuroproliferation in adult mouse olfactory epithelium.
    Neurobiology of disease, 2010, Volume: 38, Issue:3

    Topics: Adenosine Triphosphate; Aging; Animals; Arginine; Cell Proliferation; Dose-Response Relationship, Dr

2010
Cysteine sulphinate decarboxylase in chick and rat retina during development.
    Journal of neurochemistry, 1976, Volume: 27, Issue:5

    Topics: Aging; Animals; Carboxy-Lyases; Chick Embryo; Chickens; Enzyme Activation; Female; Hydrogen-Ion Conc

1976
ATP-evoked calcium responses of radial glial (Müller) cells in the postnatal rabbit retina.
    Journal of neuroscience research, 2002, Oct-15, Volume: 70, Issue:2

    Topics: Adenosine; Adenosine Triphosphate; Aging; Animals; Benzofurans; Calcium; Calcium Signaling; Cell Cou

2002
Effect of age on plasma homocysteine concentrations in young and elderly subjects considering serum vitamin concentrations and different lifestyle factors.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2004, Volume: 74, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Coffee; Female; Folic Acid; Germany; Homocy

2004
B-6 vitamers and 4-pyridoxic acid in the plasma, erythrocytes, and urine of postmenopausal women.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:4

    Topics: Adult; Aging; Erythrocytes; Estradiol; Female; Humans; Middle Aged; Nutritional Status; Postmenopaus

2004
Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2005, Volume: 15, Issue:2

    Topics: Adult; Aged; Aging; Body Mass Index; Case-Control Studies; Female; Fluorescence Polarization Immunoa

2005
Role of P2X and P2Y receptors in rat myocardial contractility during ontogeny.
    Bulletin of experimental biology and medicine, 2007, Volume: 143, Issue:6

    Topics: Adenosine Triphosphate; Aging; Animals; Drug Synergism; Heart Atria; Heart Ventricles; Myocardial Co

2007
Conversion of glucose to neurotransmitter amino acids in the brains of young and aging rats.
    Experimental gerontology, 1980, Volume: 15, Issue:6

    Topics: Age Factors; Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Female; gamma-Aminobutyric Acid; G

1980
Pyridoxal 5' phosphate involvement in age-related modifications of tyrosine aminotransferase: multiple form patterns.
    Biochimie, 1983, Volume: 65, Issue:2

    Topics: Aging; Animals; Cycloheximide; Liver; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Tosylphenylal

1983
Properties of purified tyrosine aminotransferase from adult and senescent rat liver.
    Gerontology, 1983, Volume: 29, Issue:5

    Topics: Aging; Animals; Hot Temperature; Isoelectric Point; Kinetics; Liver; Molecular Weight; Protein Proce

1983
Evaluation of pyridoxine intake and pyridoxine status among aged institutionalised people.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1984, Volume: 54, Issue:2-3

    Topics: Adult; Aged; Aging; Aspartate Aminotransferases; Dietary Proteins; Energy Intake; Erythrocytes; Fema

1984
Plasma pyridoxal phosphate in diabetics.
    The American journal of clinical nutrition, 1984, Volume: 39, Issue:5

    Topics: Adolescent; Adult; Aging; Diabetes Mellitus; Dietary Carbohydrates; Female; Humans; Middle Aged; Pyr

1984
Immunoblot detection of pyridoxal phosphate binding proteins in liver and hepatoma cytosolic extracts.
    Biochemical and biophysical research communications, 1983, Apr-15, Volume: 112, Issue:1

    Topics: Aging; Animals; Antibodies, Monoclonal; Carrier Proteins; Cytosol; Immunochemistry; Liver; Liver Neo

1983
[In vitro supplementation of pyridoxal phosphate for the optimisation of the determination of the catalytic activity of alanine aminotransferase and aspartate aminotransferase in kidney transplant patients (author's transl)].
    Clinica chimica acta; international journal of clinical chemistry, 1982, Mar-26, Volume: 120, Issue:1

    Topics: Adolescent; Adult; Aging; Alanine Transaminase; Aspartate Aminotransferases; Enzyme Activation; Fema

1982
Vitamin B-6 metabolism in the blood of young adult and senescent mice.
    Experimental gerontology, 1980, Volume: 15, Issue:5

    Topics: Aging; Animals; Kinetics; Male; Mice; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine

1980
Vitamin B-6 metabolism in the livers of young adult and senescent mice.
    Experimental gerontology, 1980, Volume: 15, Issue:5

    Topics: Aging; Animals; Liver; Male; Mice; Organophosphorus Compounds; Pyridoxal Kinase; Pyridoxal Phosphate

1980
Vitamin B-6 metabolism in the brains of young adult and senescent mice.
    Experimental gerontology, 1980, Volume: 15, Issue:5

    Topics: Aging; Animals; Brain; Kinetics; Male; Mice; Organophosphorus Compounds; Pyridoxal; Pyridoxal Kinase

1980
Reference values for alanine and aspartate aminotransferase (ALT and AST) optimized by addition of pyridoxal phosphate.
    Enzyme, 1980, Volume: 25, Issue:5

    Topics: Adult; Aging; Alanine Transaminase; Aspartate Aminotransferases; Enzyme Activation; Female; Humans;

1980
Vitamin B-6 status during childhood: tracking from 2 months to 11 years of age.
    The Journal of nutrition, 1995, Volume: 125, Issue:12

    Topics: Aging; Analysis of Variance; Aspartate Aminotransferases; Bottle Feeding; Breast Feeding; Child; Chi

1995
Infant vitamin B-6 status changes with age and with formula feeding.
    The American journal of clinical nutrition, 1994, Volume: 60, Issue:6

    Topics: Aging; Animals; Aspartate Aminotransferases; Breast Feeding; Erythrocytes; Humans; Infant; Infant Fo

1994
Bioavailability of vitamin B-6 in young and older men.
    The American journal of clinical nutrition, 1994, Volume: 60, Issue:1

    Topics: Adult; Aged; Aging; Alkaline Phosphatase; Aspartate Aminotransferases; Biological Availability; Chro

1994
Vitamin status and intake as primary determinants of homocysteinemia in an elderly population.
    JAMA, 1993, Dec-08, Volume: 270, Issue:22

    Topics: Aged; Aged, 80 and over; Aging; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Male; Nutr

1993
Characterization and developmental expression of a novel sulfotransferase for the biosynthesis of sulfoglucuronyl glycolipids in the nervous system.
    The Journal of biological chemistry, 1993, Jan-05, Volume: 268, Issue:1

    Topics: Aging; Animals; Brain; Carbohydrate Sequence; Cerebellum; Cerebral Cortex; Chromatography, Affinity;

1993
Plasma total homocysteine, B vitamins, and risk of coronary atherosclerosis.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:5

    Topics: Adult; Aging; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Erythrocytes; Fem

1997
Evidence for purinergic neurotransmission in the urinary bladder of pithed rats.
    European journal of pharmacology, 1998, May-15, Volume: 349, Issue:1

    Topics: Adenosine Triphosphate; Adrenergic Antagonists; Aging; Animals; Atropine; Blood Pressure; Decerebrat

1998
Effects of long-term parenteral administration of vitamin B6 on B6 status and some aspects of the glucose and protein metabolism of early-weaned piglets.
    The British journal of nutrition, 2001, Volume: 85, Issue:1

    Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Body Composi

2001
Reduced serum concentrations of riboflavine and ascorbic acid, and blood thiamine pyrophosphate and pyridoxal-5-phosphate in geriatric patients with and without pressure sores.
    The journal of nutrition, health & aging, 2002, Volume: 6, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Ascorbic Acid; Female; Geriatric Assessment; Humans; Male; Nutrition

2002
Selenium status and its correlates in a British national diet and nutrition survey: people aged 65 years and over.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2002, Volume: 16, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; alpha-Tocopherol; Ascorbic Acid; Carotenoids; Cholesterol; Female; G

2002
Comparative study of miscellaneous properties of cysteine sulfinate transaminase and glutamate oxaloacetate transaminase in chick retina homogenate.
    Neurochemical research, 1978, Volume: 3, Issue:1

    Topics: Aging; Animals; Aspartate Aminotransferases; Chick Embryo; Chickens; Hydrogen-Ion Concentration; Kin

1978
Pyridoxal-5-phosphate levels in rat brain assayed by a modified method using enzymic decarboxylation of L-[14C]tyrosine.
    Journal of neurochemistry, 1976, Volume: 26, Issue:2

    Topics: Aging; Animals; Brain; Brain Chemistry; Kinetics; Methods; Microchemistry; Pyridoxal Phosphate; Rats

1976
Plasma homocysteine before and after methionine loading with regard to age, gender, and menopausal status.
    European journal of clinical investigation, 1992, Volume: 22, Issue:2

    Topics: Adult; Aged; Aging; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Menopause; Methionine;

1992
Postnatal expression of glutamate decarboxylases in developing rat cerebellum.
    Neurochemical research, 1991, Volume: 16, Issue:3

    Topics: Aging; Animals; Blotting, Northern; Blotting, Western; Cerebellar Cortex; Cerebellum; gamma-Aminobut

1991
Pyridoxal-5'-phosphate and pyridoxal biokinetics in aging Wistar rats.
    Experimental gerontology, 1991, Volume: 26, Issue:6

    Topics: Aging; Animals; Biological Transport, Active; Kinetics; Male; Pyridoxal; Pyridoxal Phosphate; Pyrido

1991
Influence of age and sex on vitamin B-6 vitamer distribution and on vitamin B-6 metabolizing enzymes in Wistar rats.
    The Journal of nutrition, 1991, Volume: 121, Issue:3

    Topics: Aging; Animals; Body Weight; Diet; Female; Kidney; Liver; Male; Organ Size; Pyridoxal Phosphate; Pyr

1991
Aging and vitamin B-6 depletion: effects on plasma pyridoxal-5'-phosphate and erythrocyte aspartate aminotransferase activity coefficients in rats.
    The American journal of clinical nutrition, 1990, Volume: 51, Issue:3

    Topics: Aging; Animals; Aspartate Aminotransferases; Body Weight; Energy Intake; Erythrocytes; Male; Nutriti

1990
Age-linked alterations in fructose-2,6-bisphosphate-induced modulation of rat muscle phosphofructokinase.
    Biochemistry international, 1989, Volume: 19, Issue:6

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Aging; Animals; Citrates; Enzyme Activation; Female

1989
Plasma pyridoxal 5'-phosphate concentration and dietary vitamin B-6 intake in free-living, low-income elderly people.
    The American journal of clinical nutrition, 1989, Volume: 50, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Anthropometry; Diet; Female; Humans; Male; Pyridoxal Phosphate; Pyri

1989
Analysis of glucose-6-phosphate translocase and hexose-6-phosphate phosphohydrolase, the two obligatory components of microsomal glucose-6-phosphatase system, in rat liver.
    The Tohoku journal of experimental medicine, 1988, Volume: 155, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Antiporters; Diabetes Mellitus, Experimental; Fetus; Glucose-6-Pho

1988
Properties and ontogenic development of membrane-bound histidine decarboxylase from rat brain.
    Journal of neurochemistry, 1988, Volume: 51, Issue:5

    Topics: Aging; Animals; Brain; Carboxy-Lyases; Cell Membrane; Cytosol; Dithiothreitol; Female; Histidine Dec

1988
Effect of age on changes in plasma, erythrocyte, and urinary B-6 vitamers after an oral vitamin B-6 load.
    The American journal of clinical nutrition, 1988, Volume: 48, Issue:5

    Topics: Adult; Aged; Aging; Erythrocytes; Humans; Male; Middle Aged; Pyridoxal Phosphate; Pyridoxic Acid; Py

1988
Intestinal absorption of pyridoxal 5'-phosphate at physiological levels in rats.
    Journal of nutritional science and vitaminology, 1988, Volume: 34, Issue:6

    Topics: Aging; Animals; Biological Transport; Hydrolysis; Intestinal Absorption; Male; Pyridoxal; Pyridoxal

1988
Influence of vitamin B6 on age dependent changes in blood urea.
    Indian journal of experimental biology, 1985, Volume: 23, Issue:2

    Topics: Aging; Alanine Transaminase; Animals; Arginase; Isoenzymes; Kidney; Liver; Male; Pyridoxal Phosphate

1985
Some properties of guinea pig brain glutamate decarboxylase and its inhibition by the convulsant allylglycine (2-amino-4-pentenoic acid).
    Journal of neurochemistry, 1974, Volume: 23, Issue:2

    Topics: Aging; Allyl Compounds; Amino Acids; Animals; Anions; Brain; Carbon Radioisotopes; Carboxy-Lyases; C

1974
Alpha-glucan-phosphorylase in the striated muscle of the developing embryo of Gallus domesticus.
    Enzymologia, 1968, Jan-31, Volume: 34, Issue:1

    Topics: Adenine Nucleotides; Aging; Animals; Benzoates; Chick Embryo; Chickens; Cyclic AMP; Cysteine; Glucos

1968
Occurrence and distribution of aromatic L-amino acid (L-DOPA) decarboxylase in the human brain.
    Journal of neurochemistry, 1972, Volume: 19, Issue:6

    Topics: 5-Hydroxytryptophan; Aged; Aging; Animals; Basal Ganglia; Brain; Carbon Isotopes; Cats; Cattle; Caud

1972
A simple enzymic assay for pyridoxal phosphate.
    Analytical biochemistry, 1970, Volume: 34, Issue:2

    Topics: Adult; Aging; Alkaline Phosphatase; Carbon Dioxide; Carbon Isotopes; Female; Humans; Kinetics; Male;

1970
Some aspects of the metabolism of urethane and N-hydroxyurethane in rodents.
    The Biochemical journal, 1968, Volume: 106, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Carbamates; Chloromercuribenzoates; Cyanides; Depression, Chemical

1968
Variation of the norepinephrine metabolism of the rat heart with age.
    Gerontologia, 1965, Volume: 11, Issue:1

    Topics: Aging; Animals; Carbon Isotopes; Carboxy-Lyases; Catecholamines; Dopa Decarboxylase; Female; In Vitr

1965