pyridoxal phosphate has been researched along with Acute Hepatic Failure in 3 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fomepizole (4-methylpyrazole) is safe and has shown efficacy in preclinical models, human hepatocytes and in volunteers against APAP overdose." | 2.66 | Novel strategies for the treatment of acetaminophen hepatotoxicity. ( Akakpo, JY; Jaeschke, H; Ramachandran, A, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Akakpo, JY | 1 |
| Ramachandran, A | 1 |
| Jaeschke, H | 1 |
| Bedda, S | 1 |
| Laurent, A | 1 |
| Conti, F | 1 |
| Chéreau, C | 1 |
| Tran, A | 1 |
| Tran-Van Nhieu, J | 1 |
| Jaffray, P | 1 |
| Soubrane, O | 1 |
| Goulvestre, C | 1 |
| Calmus, Y | 1 |
| Weill, B | 1 |
| Batteux, F | 1 |
| Karlsson, JO | 1 |
1 review available for pyridoxal phosphate and Acute Hepatic Failure
| Article | Year |
|---|---|
Novel strategies for the treatment of acetaminophen hepatotoxicity.
Topics: Acetaminophen; Acetylcysteine; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Drug Over | 2020 |
2 other studies available for pyridoxal phosphate and Acute Hepatic Failure
| Article | Year |
|---|---|
Mangafodipir prevents liver injury induced by acetaminophen in the mouse.
Topics: Acetaminophen; Animals; Antibodies, Monoclonal; Antioxidants; Carcinoma, Hepatocellular; Caspase 3; | 2003 |
Antioxidant activity of mangafodipir is not a new finding.
Topics: Animals; Antioxidants; Cardiotonic Agents; Edetic Acid; Liver Failure, Acute; Mice; Pyridoxal Phosph | 2004 |