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pyridoxal phosphate and Acute Disease

pyridoxal phosphate has been researched along with Acute Disease in 15 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"To determine the pharmacokinetic (PK) profile of manganese (Mn) after a 2-hour intravenous infusion of mangafodipir at 5 micromol/kg body weight and to correlate Mn concentrations with oxidative stress, early decrease in serum total bilirubin concentration, and prothrombin time (PT) in chronic alcoholic patients with acute alcoholic hepatitis."9.14Pharmacokinetic-pharmacodynamic modeling of manganese after a single intravenous infusion of mangafodipir in patients with acute alcoholic hepatitis. ( Batteux, F; Debray, M; Hirt, D; Laurent, A; Pavlovic, S; Poupon, J; Richardet, JP; Sogni, P; Treluyer, JM; Urien, S; Weill, B, 2009)
"To determine the pharmacokinetic (PK) profile of manganese (Mn) after a 2-hour intravenous infusion of mangafodipir at 5 micromol/kg body weight and to correlate Mn concentrations with oxidative stress, early decrease in serum total bilirubin concentration, and prothrombin time (PT) in chronic alcoholic patients with acute alcoholic hepatitis."5.14Pharmacokinetic-pharmacodynamic modeling of manganese after a single intravenous infusion of mangafodipir in patients with acute alcoholic hepatitis. ( Batteux, F; Debray, M; Hirt, D; Laurent, A; Pavlovic, S; Poupon, J; Richardet, JP; Sogni, P; Treluyer, JM; Urien, S; Weill, B, 2009)
"The relationship between pyridoxal phosphate deficiency and activities of serum and liver aminotransferases was studied in 12 patients with alcoholic hepatitis."3.67Relationship between pyridoxal 5'-phosphate deficiency and aminotransferase levels in alcoholic hepatitis. ( Boitnott, J; Diehl, AM; Herlong, HF; Mezey, E; Potter, J; Van Duyn, MA, 1984)
"The concentration of serum pyridoxal phosphate was determined before and 15, 30, 60, 90, and 120 minutes following an oral load test with 5 mg pyridoxine hydrochloride/kg body weight in 14 children with acute celiac disease and in 15 control subjects."3.66Vitamin B-6 absorption in children with acute celiac disease and in control subjects. ( Reinken, L; Zieglauer, H, 1978)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's3 (20.00)18.2507
2000's4 (26.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirt, D1
Richardet, JP1
Urien, S1
Poupon, J1
Sogni, P1
Batteux, F1
Laurent, A1
Pavlovic, S1
Debray, M1
Treluyer, JM1
Weill, B1
Kim, KW1
Park, MS1
Yu, JS1
Chung, JP1
Ryu, YH1
Lee, SI1
Lee, KS1
Yoon, SW1
Lee, KH1
Kim, TH2
Yang, DH2
Choi, JW2
Kim, ST2
Yoon, JH2
Shin, JH2
Seo, JB2
Gong, GY1
Lim, TH2
Diehl, AM1
Potter, J1
Boitnott, J1
Van Duyn, MA1
Herlong, HF1
Mezey, E1
Ahlström, H1
Gehl, HB1
Karlsson, JO1
Mortensen, E1
Pedersen, HK1
Sager, G1
Refsum, H1
Reinken, L1
Zieglauer, H1
Horder, M1
Moore, RE1
Bowers, GN1
Mitchell, D1
Wagner, C1
Stone, WJ1
Wilkinson, GR1
Schenker, S1
Vech, RL1
Lumeng, L1
Li, TK1
Litvinenko, IuA1
Kolonina, IR1
Sokolov, AV1
Gorbunova, NA1
Chuvykin, MB1
Pavlova, MP1
Cavanagh, JB1
Ridley, AR1
Burg, G1

Reviews

2 reviews available for pyridoxal phosphate and Acute Disease

ArticleYear
Overview of MnDPDP as a pancreas-specific contrast agent for MR imaging.
    Acta radiologica (Stockholm, Sweden : 1987), 1997, Volume: 38, Issue:4 Pt 2

    Topics: Acute Disease; Contrast Media; Edetic Acid; Humans; Magnetic Resonance Imaging; Manganese; Pancreas;

1997
The nature of the neuropathy complicating acute intermittent porphyria.
    Lancet (London, England), 1967, Nov-11, Volume: 2, Issue:7524

    Topics: Acute Disease; Animals; Humans; Ligases; Nerve Degeneration; Nervous System Diseases; Porphyrias; Py

1967

Trials

1 trial available for pyridoxal phosphate and Acute Disease

ArticleYear
Pharmacokinetic-pharmacodynamic modeling of manganese after a single intravenous infusion of mangafodipir in patients with acute alcoholic hepatitis.
    Therapeutic drug monitoring, 2009, Volume: 31, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Anesthetics, Local; Antineoplastic Combined Chemotherapy Pro

2009

Other Studies

12 other studies available for pyridoxal phosphate and Acute Disease

ArticleYear
Acute cholecystitis at T2-weighted and manganese-enhanced T1-weighted MR cholangiography: preliminary study.
    Radiology, 2003, Volume: 227, Issue:2

    Topics: Acute Disease; Adult; Aged; Cholangiography; Cholecystitis; Contrast Media; Edetic Acid; Female; Hum

2003
Manganese dipyridoxyl diphosphate (MnDPDP)-enhanced magnetic resonance imaging of acute reperfused myocardial injury in a cat model: part I: comparison with pathologic examination.
    Investigative radiology, 2005, Volume: 40, Issue:1

    Topics: Acute Disease; Animals; Cats; Contrast Media; Disease Models, Animal; Edetic Acid; Magnetic Resonanc

2005
Manganese dipyridoxyl diphosphate (MnDPDP)-enhanced magnetic resonance imaging of acute reperfused myocardial injury in a cat model: part II: comparison with cine magnetic resonance imaging.
    Investigative radiology, 2005, Volume: 40, Issue:1

    Topics: Acute Disease; Animals; Cats; Contrast Media; Disease Models, Animal; Edetic Acid; Magnetic Resonanc

2005
Relationship between pyridoxal 5'-phosphate deficiency and aminotransferase levels in alcoholic hepatitis.
    Gastroenterology, 1984, Volume: 86, Issue:4

    Topics: Acute Disease; Adult; Alanine Transaminase; Aspartate Aminotransferases; Female; Hepatitis, Alcoholi

1984
Cardiovascular effects of MnDPDP and MnCl2 in dogs with acute ischaemic heart failure.
    Acta radiologica (Stockholm, Sweden : 1987), 1997, Volume: 38, Issue:4 Pt 2

    Topics: Acute Disease; Animals; Cardiovascular System; Chlorides; Contrast Media; Depression, Chemical; Dise

1997
Vitamin B-6 absorption in children with acute celiac disease and in control subjects.
    The Journal of nutrition, 1978, Volume: 108, Issue:10

    Topics: Acute Disease; Celiac Disease; Humans; Intestinal Absorption; Jejunum; Pyridoxal Phosphate; Pyridoxi

1978
Aspartate aminotransferase activity in human serum. Factors to be considered in supplementation with pyridoxal 5'-phosphate in vitro.
    Clinical chemistry, 1976, Volume: 22, Issue:11

    Topics: Acute Disease; Aspartate Aminotransferases; Enzyme Activation; Evaluation Studies as Topic; Glutamat

1976
Abnormal regulation of plasma pyridoxal 5'-phosphate in patients with liver disease.
    Gastroenterology, 1976, Volume: 71, Issue:6

    Topics: Acute Disease; Adult; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Diseases; Liver Functi

1976
Vitamin B6 metabolism in chronic alcohol abuse The effect of ethanol oxidation on hepatic pyridoxal 5'-phosphate metabolism.
    The Journal of clinical investigation, 1975, Volume: 55, Issue:5

    Topics: Acute Disease; Alcoholic Intoxication; Animals; Chronic Disease; Humans; In Vitro Techniques; Liver;

1975
[Study of the effectiveness of artificial oxygen carrier on the hemoglobin base in blood loss replacement in dogs].
    Gematologiia i transfuziologiia, 1991, Volume: 36, Issue:8

    Topics: Acute Disease; Animals; Blood Substitutes; Bloodletting; Disease Models, Animal; Dogs; Drug Carriers

1991
[Pyridoxal and pyridoxamine phosphate levels in the plasma and bone marrow of children with acute leukemia].
    Pediatriia, 1987, Issue:11

    Topics: Acute Disease; Adolescent; Bone Marrow; Child; Child, Preschool; Humans; Infant; Leukemia; Pyridoxal

1987
[Therapy of porphyrias].
    Deutsche medizinische Wochenschrift (1946), 1971, May-21, Volume: 96, Issue:21

    Topics: Acute Disease; Adenine Nucleotides; Antimalarials; Bicarbonates; Bloodletting; Deferoxamine; Diet Th

1971