pyridoxal phosphate has been researched along with Abnormalities, Drug-Induced in 3 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Skeletal malformations, identical to those seen in the previous study, were increased in a dose-dependent manner with the highest incidence occurring in fetuses from females dosed from days 15-17 of gestation." | 1.29 | Developmental toxicity of mangafodipir trisodium and manganese chloride in Sprague-Dawley rats. ( Blazak, WF; Gray, TJ; Treinen, KA, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Treinen, KA | 2 |
| Gray, TJ | 2 |
| Blazak, WF | 3 |
| Brown, GL | 2 |
| Denny, KH | 1 |
| Grant, D | 1 |
3 other studies available for pyridoxal phosphate and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Developmental toxicity of mangafodipir trisodium and manganese chloride in Sprague-Dawley rats.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Chlorides; Contrast Media; Dose-Response Relat | 1995 |
Developmental toxicity study of mangafodipir trisodium injection (MnDPDP) in New Zealand white rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Contrast Media; Edetic Acid; Embryonic and Fetal | 1996 |
The reproductive toxicology of intravenously administered MnDPDP in the rat and rabbit.
Topics: Abnormalities, Drug-Induced; Animals; Contrast Media; Dose-Response Relationship, Drug; Edetic Acid; | 1997 |