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pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid and Cystitis

pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid has been researched along with Cystitis in 4 studies

pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid: a novel antagonist that selectively blocks P2 purinoceptor receptors; a useful tool to study co-transmission in tissues when ATP and coexisting neurotransmitters act in concert
5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid : An arenesulfonic acid that is pyridoxal 5'-phosphate carrying an additional 2,4-disulfophenylazo substituent at position 6.

Cystitis: Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.

Research Excerpts

ExcerptRelevanceReference
"To clarify the basic mechanism involved in the pathophysiology of cystitis by characterizing the urodynamic parameters, pharmacologically relevant (muscarinic and purinergic) receptors, and the in vivo release of adenosine triphosphate (ATP) in the bladder of hydrochloric acid (HCl)-treated rats."7.76Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis. ( Fujino, T; Kageyama, A; Nozawa, Y; Yamada, S; Yoshida, A, 2010)
" In this study, we investigated the effect of the recently developed P2X3 and P2X2/3 receptor antagonist A-317491 on cyclophosphamide (CYP)-induced cystitis to determine whether a P2X receptor antagonist could be beneficial for the treatment of bladder overactivity induced by CYP."7.74Therapeutic effects of the putative P2X3/P2X2/3 antagonist A-317491 on cyclophosphamide-induced cystitis in rats. ( Ikeda, M; Ito, K; Iwami, A; Katsura, H, 2008)
"To clarify the basic mechanism involved in the pathophysiology of cystitis by characterizing the urodynamic parameters, pharmacologically relevant (muscarinic and purinergic) receptors, and the in vivo release of adenosine triphosphate (ATP) in the bladder of hydrochloric acid (HCl)-treated rats."3.76Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis. ( Fujino, T; Kageyama, A; Nozawa, Y; Yamada, S; Yoshida, A, 2010)
" In this study, we investigated the effect of the recently developed P2X3 and P2X2/3 receptor antagonist A-317491 on cyclophosphamide (CYP)-induced cystitis to determine whether a P2X receptor antagonist could be beneficial for the treatment of bladder overactivity induced by CYP."3.74Therapeutic effects of the putative P2X3/P2X2/3 antagonist A-317491 on cyclophosphamide-induced cystitis in rats. ( Ikeda, M; Ito, K; Iwami, A; Katsura, H, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gonzalez, EJ1
Heppner, TJ1
Nelson, MT1
Vizzard, MA1
Yoshida, A1
Kageyama, A1
Fujino, T1
Nozawa, Y1
Yamada, S1
Ito, K1
Iwami, A1
Katsura, H1
Ikeda, M1
Yu, Y1
de Groat, WC1

Other Studies

4 other studies available for pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid and Cystitis

ArticleYear
Purinergic signalling underlies transforming growth factor-β-mediated bladder afferent nerve hyperexcitability.
    The Journal of physiology, 2016, 07-01, Volume: 594, Issue:13

    Topics: Adenosine Triphosphate; Animals; Connexins; Cyclophosphamide; Cystitis; Male; Mice, Inbred C57BL; Ne

2016
Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis.
    Urology, 2010, Volume: 76, Issue:4

    Topics: Adenosine Triphosphate; Animals; Benzhydryl Compounds; Benzofurans; Cresols; Cystitis; Disease Model

2010
Therapeutic effects of the putative P2X3/P2X2/3 antagonist A-317491 on cyclophosphamide-induced cystitis in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 377, Issue:4-6

    Topics: Animals; Cyclophosphamide; Cystitis; Disease Models, Animal; Dose-Response Relationship, Drug; Femal

2008
Sensitization of pelvic afferent nerves in the in vitro rat urinary bladder-pelvic nerve preparation by purinergic agonists and cyclophosphamide pretreatment.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:5

    Topics: Action Potentials; Adenosine Triphosphate; Anesthetics, Local; Animals; Antineoplastic Agents, Alkyl

2008