pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid has been researched along with Ache in 8 studies
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid: a novel antagonist that selectively blocks P2 purinoceptor receptors; a useful tool to study co-transmission in tissues when ATP and coexisting neurotransmitters act in concert
5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid : An arenesulfonic acid that is pyridoxal 5'-phosphate carrying an additional 2,4-disulfophenylazo substituent at position 6.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Furthermore, using an ex-vivo assay system, we found that compound 36j potently inhibited pain signaling in the rat dorsal horn with 20 μM 36j displaying 65% inhibition while 20 μM pregabalin, a clinically available drug, showed only 31% inhibition." | 3.79 | Design and synthesis of potent and selective P2X₃ receptor antagonists derived from PPADS as potential pain modulators. ( Cho, JH; Jung, KY; Jung, Y; Kim, MH; Kim, YC; Ko, H; Park, CS, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cho, JH | 1 |
| Jung, KY | 1 |
| Jung, Y | 1 |
| Kim, MH | 1 |
| Ko, H | 1 |
| Park, CS | 1 |
| Kim, YC | 1 |
| McCleskey, EW | 1 |
| Tsuda, M | 2 |
| Shigemoto-Mogami, Y | 1 |
| Koizumi, S | 1 |
| Mizokoshi, A | 1 |
| Kohsaka, S | 1 |
| Salter, MW | 1 |
| Inoue, K | 2 |
| Martucci, C | 1 |
| Trovato, AE | 1 |
| Costa, B | 1 |
| Borsani, E | 1 |
| Franchi, S | 1 |
| Magnaghi, V | 1 |
| Panerai, AE | 1 |
| Rodella, LF | 1 |
| Valsecchi, AE | 1 |
| Sacerdote, P | 1 |
| Colleoni, M | 1 |
| Ueno, S | 1 |
| Masaki, E | 1 |
| Ebisawa, T | 1 |
| Kondo, I | 1 |
| Hayashida, K | 1 |
| Matsumoto, Y | 1 |
| Kawamura, M | 1 |
| Fukuhara, N | 1 |
| Imai, Y | 1 |
| Sakakibara, A | 1 |
| Morita, K | 1 |
| Kitayama, S | 1 |
| Tanne, K | 1 |
| Dohi, T | 1 |
| Honore, P | 1 |
| Mikusa, J | 1 |
| Bianchi, B | 1 |
| McDonald, H | 1 |
| Cartmell, J | 1 |
| Faltynek, C | 1 |
| Jarvis, MF | 1 |
8 other studies available for pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid and Ache
| Article | Year |
|---|---|
Design and synthesis of potent and selective P2X₃ receptor antagonists derived from PPADS as potential pain modulators.
Topics: Animals; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Structure; Oocytes; Pain; | 2013 |
Neurobiology: new player in pain.
Topics: Animals; Chronic Disease; Microglia; Pain; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; | 2003 |
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Cells, Cultured; Disease Models, Animal; Male; Microgli | 2003 |
The purinergic antagonist PPADS reduces pain related behaviours and interleukin-1 beta, interleukin-6, iNOS and nNOS overproduction in central and peripheral nervous system after peripheral neuropathy in mice.
Topics: Animals; Behavior, Animal; Central Nervous System; Drug Delivery Systems; Interleukin-1beta; Interle | 2008 |
Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Capsaicin; Formaldehyde; Male; Mice; Motor Activi | 1999 |
P2-purinergic receptor antagonists reduce the minimum alveolar concentration of inhaled volatile anesthetics.
Topics: Adenosine Triphosphate; Anesthesia; Anesthetics, Inhalation; Animals; Antineoplastic Agents; Brain; | 2000 |
Regulation of the development of allodynia by intrathecally administered P2 purinoceptor agonists and antagonists in mice.
Topics: Adenosine Triphosphate; Animals; Dinoprostone; Dizocilpine Maleate; Injections, Spinal; Male; Mice; | 2000 |
TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: comparison with reference analgesics.
Topics: Abdomen; Acetic Acid; Adenosine Triphosphate; Analgesics; Animals; Antineoplastic Agents; Behavior, | 2002 |