pyridostigmine bromide has been researched along with Disease Models, Animal in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (14.29) | 29.6817 |
| 2010's | 37 (58.73) | 24.3611 |
| 2020's | 17 (26.98) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Bishay, AE; Carabelli, B; Chinthirla, DB; Currás-Collazo, MC; Denys, ME; Hsiao, A; Kozlova, EV; Tran, JD; Zur Nieden, NI | 1 |
| Bishay, AE; Carabelli, B; Crawford, MS; Curras-Collazo, MC; Denys, ME; Hsiao, A; Kozlova, EV; Liu, R; Macbeth, JC; McCole, DF; Piamthai, V; Zur Nieden, NI | 1 |
| Iannucci, J; Nizamutdinov, D; Shapiro, LA | 1 |
| Abdullah, L; Ait-Ghezala, G; Browning, M; Crawford, F; Ferguson, S; Gratkowski, A; Hahn-Townsend, C; McCartan, R; Morin, A; Mouzon, B; Mullan, M; Ojo, J; Sullivan, K | 1 |
| Harrison, K; Klaunig, JE; Koyama, S; Meng, F; Shetty, AK; Slevin, E; Wan, Y; Wu, C | 1 |
| Carreras, I; Dedeoglu, A; Jung, Y; Lopez-Benitez, J; Tognoni, CM | 1 |
| Ayala, KE; Burzynski, HE; Dufala, HA; Eberl, BR; Fadel, JR; Frick, MA; Grillo, CA; Hollis, F; Macht, VA; McQuail, JA; Reagan, LP; Woodruff, JL | 1 |
| Beeson, D; Cetin, H; Cheung, J; Cossins, J; Liu, WW; Maxwell, S; Palace, J; Ramjattan, H; Rodriguez Cruz, PM; Vanhaesebrouck, AE; Webster, R; Wickens, J | 1 |
| Bose, D; Chatterjee, S; Holland, LA; Horner, RD; Janulewicz Lloyd, P; Kimono, D; Klimas, N; Lim, ES; Maqsood, R; Mondal, A; Seth, RK; Sullivan, K | 1 |
| Agarwal, H; Banerjee, S; Chand, HS; Raizada, V; Roy, S; Singh, SP; Sopori, M | 1 |
| Pai, YC; Yu, LC | 1 |
| Carpenter, JM; Filipov, NM; Gordon, HE; Harn, DA; Ludwig, HD; Norberg, T; Wagner, JJ | 1 |
| Arcanjo, DDR; Cavalcante, GL; da Silva, MTB; Ferreira, FN; Filho, ALMM; Sabino, JPJ; Soriano, RN | 1 |
| Fried, D; Grubišić, V; Gulbransen, BD; Hernandez, S; Morales-Soto, W | 1 |
| Lenina, OA; Masson, P; Petrov, KA; Semenov, VE; Zobov, VV; Zueva, IV | 1 |
| Gerzanich, V; Ivanova, S; Keledjian, K; Kim, K; Moyer, M; Negoita, S; Semick, S; Simard, JM; Tsymbalyuk, O | 1 |
| Ali, MA; Issotina Zibrila, A; Kang, Y; Li, C; Liu, J; Liu, K; Osei, JA; Sun, Y; Wang, Z; Zafar, S | 1 |
| Clark, JD; Goba, L; Huang, TT; Nguyen, H; Sahbaie, P; Sul, J; Suzaki, A | 1 |
| Kelly, KA; Locker, AR; Michalovicz, LT; Miller, DB; Miller, JV; O'Callaghan, JP | 1 |
| Amancio, GCS; Barcellos, NMS; Cazorla, O; Grabe-Guimarães, A; Haikel, D; Lacampagne, A; Matecki, S; Moreau, J | 1 |
| Bezerra, OC; Consolim-Colombo, FM; de Angelis, K; Dourado, PM; França, CM; Irigoyen, MCC; Llesuy, S; Loleiro, TCA; Malfitano, C; Neves, GA; Rocha, JA; Souza, PRM; Teixeira Gomes, M; Ulloa, L | 1 |
| Bogaard, HJ; Casali, AG; Casali, KR; da Silva Gonçalves Bós, D; de Man, FS; Dorfmüller, P; Dos Remedios, C; Goumans, MJ; Guignabert, C; Handoko, ML; Humbert, M; Kurakula, K; Kuster, DWD; Rol, N; Sun, XQ; Szulcek, R; Tu, L; Van Der Bruggen, CEE; van der Velden, J; Vonk-Noordegraaf, A; Wijnker, PJM | 1 |
| Aytan, N; Blusztajn, JK; Carreras, I; Choi, JK; Crabtree, L; Dedeoglu, A; Jenkins, BG; Lehar, M; Leite-Morris, K; Mellott, T | 1 |
| Cooper, BY; Flunker, LD; Johnson, RD; Nutter, TJ | 1 |
| Grillo, CA; Macht, VA; Reagan, LP; Wilson, MA; Wood, CS; Woodruff, JL | 1 |
| Barnes, Z; Fletcher, MA; Kelly, KA; Klimas, NG; Lasley, SM; Locker, AR; Michalovicz, LT; Miller, DB; Miller, JV; Morris, M; O'Callaghan, JP | 1 |
| Cui, YL; Li, DL; Wu, Q; Xu, M; Xue, RQ; Yang, S; Yu, XJ; Zang, WJ; Zhao, M | 1 |
| Barboza, CA; Caperuto, EC; Carrozzi, N; Dourado, PMM; Fukushima, AR; Irigoyen, MC; Machi, JF; Morris, M; Mostarda, CT; Nathanson, L; Rodrigues, B | 1 |
| Bruun, DA; Guignet, M; Harvey, DJ; Lein, PJ | 1 |
| Cau, SBA; Lataro, RM; Mestriner, FL; Salgado, HC; Silva, MAB; Tostes, RCA | 1 |
| Fadel, JR; Grillo, CA; Macht, VA; Maissy, ES; Reagan, LP; Wilson, MA; Woodruff, JL | 1 |
| Attaluri, S; Gitai, D; Kodali, M; Madhu, LN; Shetty, AK; Shuai, B; Upadhya, R | 1 |
| Abdullah, L; Crawford, F; Cseresznye, A; Darcey, T; Evans, JE; Hammock, B; Hongsibsong, S; Joshi, U; Keegan, AP; Klimas, N; Langlois, H; Mullan, M; Oberlin, S; Ojo, J; Paris, D; Pearson, A; Raya, B; Saltiel, N; Stern, LJ; Sullivan, K; Vasylieva, N | 1 |
| Hattiangady, B; Parihar, VK; Shetty, AK; Shuai, B | 1 |
| da Silva, CA; Fazan, R; Giusti, H; Glass, ML; Sabino, JP; Salgado, HC | 1 |
| Cheng, XW; Duan, JL; Hao, C; Huang, ZH; Lu, W; Murohara, T; Shi, YQ; Song, SW; Su, DF | 1 |
| Becari, C; Corrêa, WG; de Oliveira, M; do Carmo, JM; Durand, MT; Fazan, R; Prado, CM; Salgado, HC; Tezini, GC | 1 |
| Abdullah, L; Ait-Ghezala, G; Crawford, F; Crynen, G; Mathura, V; Mullan, M; Mullan, MJ; Nissanka, N; Reed, J; Tweed, M; Zakirova, Z | 1 |
| Cooper, BY; Johnson, RD; Nutter, TJ | 2 |
| Araujo, JE; Blanco, JH; Carvalho, EE; Gardim, CB; Gastaldi, AC; Oliveira, LF; Simões, MV; Souza, HC | 1 |
| Alves, G; Coelho, O; Consolim-Colombo, FM; França, CM; Irigoyen, MC; Kallás, EG; Lacchini, S; Ribeiro, SP; Rocha, JA | 1 |
| Clark, ME; Farmer, DM; Kurata, WE; Matsumoto, KW; Pierce, LM | 1 |
| Bealer, SL; Dudek, FE; Pouliot, W; Roach, B | 1 |
| Amourette, C; Barbier, L; Diserbo, M; Fauquette, W; Lamproglou, I; Viret, R; Zoppe, A | 1 |
| Blobner, M; Fink, H; Frick, CG; Helming, M; Martyn, JA | 1 |
| Kaas, B; Kohn, RE; Leatherman, A; Schleidt, S; Vaidya, AR | 1 |
| Grubbs, RD; Lucot, JB; Mauck, B; Paton, S | 1 |
| Al-Diwani, A; Bouzat, C; Buckingham, SD; Hernando, G; Jones, AK; Jones, R; Maynard, TP; Rayes, D; Sattelle, DB | 1 |
| Abbs, S; Beeson, D; Cullup, T; Dowling, JJ; Feng, L; Jungbluth, H; Knight, RK; Kress, W; Laporte, J; Lees, MM; Lillis, S; Manzur, AY; Mills, KR; Muntoni, F; Pike, MG; Pitt, MC; Robb, SA; Sewry, CA | 1 |
| Beggs, AH; Buj-Bello, A; Dowling, JJ; Dulin-Smith, AN; Durban, AN; Joubert, R; Li, X; Low, SE; Marshall, JT; Marshall, ML; Messaddeq, N; Pierson, CR; Snyder, AD | 1 |
| Abdullah, L; Ait-Ghezala, G; Bishop, A; Crawford, FC; Crynen, G; Evans, JE; Ferro, A; Mullan, CM; Mullan, MA; Mullan, MJ; Pelot, R; Phillips, J; Reed, JM | 1 |
| Joosen, MJ; Kuijpers, WC; Noort, D; van der Schans, MJ; van Helden, HP | 1 |
| Clarke, NF; Dowling, JJ; Feldman, EL; Gibbs, EM; Oates, EC; Rose, K; Webster, R | 1 |
| Dudley, A; Eudaly, E; Eudaly, J; Gilkeson, G; Keil, DE; Lee, A; Peden-Adam, MM; Robbs, J; Zeigler, J | 1 |
| Abdel-Rahman, A; Abou-Donia, M; Abou-Donia, S; El-Masry, E; Shetty, A | 1 |
| Benjamin, A; McDonough, JH; McMonagle, JD; Rowland, T; Shih, TM | 1 |
| Adani, R; Amitai, G; Avila, J; Farías, GG; Godoy, JA; Inestrosa, NC; Meshulam, H; Vázquez, MC | 1 |
| Abraham, S; Cohen, G; Dachir, S; Gilat, E; Herskovitz, M; Kapon, J; Levy, A; Raveh, L; Teitelbaum, Z | 1 |
| McDonough, JH; Shih, TM | 1 |
| Beck, KD; Beldowicz, D; Brennan, FX; Moldow, RL; Ottenweller, JE; Servatius, RJ; Zhu, G | 1 |
| Bressler, J; Pope, CN; Pruett, S; Song, X; Tian, H | 1 |
3 review(s) available for pyridostigmine bromide and Disease Models, Animal
| Article | Year |
|---|---|
Dysbiosis in gastrointestinal pathophysiology: Role of the gut microbiome in Gulf War Illness.
Topics: Animals; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Gulf War; Mice; Permethrin; Persian Gulf Syndrome; Pyridostigmine Bromide | 2023 |
Timing of decontamination and treatment in case of percutaneous VX poisoning: a mini review.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Decontamination; Disease Models, Animal; Guinea Pigs; Organophosphate Poisoning; Organothiophosphorus Compounds; Procyclidine; Pyridostigmine Bromide; Scopolamine; Skin; Time Factors | 2013 |
Central nervous system effects from a peripherally acting cholinesterase inhibiting agent: interaction with stress or genetics.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Basal Ganglia; Behavior, Animal; Brain Chemistry; Cholinesterase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Electroshock; Genetic Predisposition to Disease; Genetic Variation; Muscle Contraction; Nerve Tissue Proteins; Persian Gulf Syndrome; Prosencephalon; Pyridostigmine Bromide; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Salivation; Stress, Physiological | 2001 |
60 other study(ies) available for pyridostigmine bromide and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Persistent exercise fatigue and associative learning deficits in combination with transient glucose dyshomeostasis in a mouse model of Gulf War Illness.
Topics: Animals; Disease Models, Animal; Fatigue; Glucose; Humans; Learning Disabilities; Male; Mice; Persian Gulf Syndrome; Pyridostigmine Bromide | 2022 |
Induction of distinct neuroinflammatory markers and gut dysbiosis by differential pyridostigmine bromide dosing in a chronic mouse model of GWI showing persistent exercise fatigue and cognitive impairment.
Topics: Animals; Biomarkers; Cholinesterase Inhibitors; Cognitive Dysfunction; Disease Models, Animal; Dose-Response Relationship, Drug; Dysbiosis; Endotoxemia; Fatigue; Gastrointestinal Microbiome; Gene Expression Profiling; Gene Expression Regulation; Gliosis; Male; Mice; Mice, Inbred C57BL; Neuralgia; Neuroinflammatory Diseases; Persian Gulf Syndrome; Physical Conditioning, Animal; Pyridostigmine Bromide | 2022 |
Neurogenesis and chronic neurobehavioral outcomes are partially improved by vagus nerve stimulation in a mouse model of Gulf War illness.
Topics: Animals; Disease Models, Animal; Gulf War; Mice; Neurogenesis; Permethrin; Persian Gulf Syndrome; Pyridostigmine Bromide; Vagus Nerve Stimulation | 2022 |
Impact of gulf war toxic exposures after mild traumatic brain injury.
Topics: Animals; Brain Concussion; Brain Injuries, Traumatic; Disease Models, Animal; Gulf War; Mice; Permethrin; Pesticides; Pharmaceutical Preparations; Pyridostigmine Bromide | 2022 |
Fingolimod mitigates memory loss in a mouse model of Gulf War Illness amid decreasing the activation of microglia, protein kinase R, and NFκB.
Topics: Amnesia; Animals; Disease Models, Animal; Fingolimod Hydrochloride; Gulf War; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Microglia; Neuroinflammatory Diseases; NF-kappa B; Persian Gulf Syndrome; Protein Kinases; Pyridostigmine Bromide | 2023 |
Delayed cognitive impairments in a rat model of Gulf War Illness are stimulus-dependent.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Cognitive Dysfunction; Disease Models, Animal; Gulf War; Lipopolysaccharides; Memory Disorders; Persian Gulf Syndrome; Pyridostigmine Bromide; Rats | 2023 |
β2-Adrenergic receptor agonists ameliorate the adverse effect of long-term pyridostigmine on neuromuscular junction structure.
Topics: Action Potentials; Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Humans; Mice; Myasthenic Syndromes, Congenital; Neuromuscular Junction; Pyridostigmine Bromide; Synaptic Transmission | 2019 |
Gut DNA Virome Diversity and Its Association with Host Bacteria Regulate Inflammatory Phenotype and Neuronal Immunotoxicity in Experimental Gulf War Illness.
Topics: Animals; Antiviral Agents; Bacteria; Cytokines; Disease Models, Animal; DNA; Dysbiosis; Gastrointestinal Microbiome; Immunity, Innate; Inflammation; Male; Mice; Mice, Inbred C57BL; Neurons; Permethrin; Persian Gulf Syndrome; Phenotype; Pyridostigmine Bromide; Ribavirin; Viruses | 2019 |
Acetylcholinesterase Inhibitor Pyridostigmine Bromide Attenuates Gut Pathology and Bacterial Dysbiosis in a Murine Model of Ulcerative Colitis.
Topics: Acetylcholinesterase; Animals; Anti-Inflammatory Agents; Cholinesterase Inhibitors; Colitis, Ulcerative; Colon; Cytokines; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; GPI-Linked Proteins; Inflammation Mediators; Mucin-2; Pyridostigmine Bromide; Th2 Cells | 2020 |
Is "Cholinergic" Stimulus Useful for Ulcerative Colitis Treatment?
Topics: Acetylcholinesterase; Animals; Colitis, Ulcerative; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Mice; Pyridostigmine Bromide | 2020 |
Neurochemical and neuroinflammatory perturbations in two Gulf War Illness models: Modulation by the immunotherapeutic LNFPIII.
Topics: Amino Sugars; Animals; Biogenic Monoamines; Brain; Brain Chemistry; DEET; Disease Models, Animal; Encephalitis; Humans; Immunotherapy; Male; Mice, Inbred C57BL; Permethrin; Persian Gulf Syndrome; Pesticides; Polysaccharides; Pyridostigmine Bromide; Spleen | 2020 |
Acetylcholinesterase inhibition prevents alterations in cardiovascular autonomic control and gastric motility in L-NAME-induced hypertensive rats.
Topics: Acetylcholinesterase; Animals; Arterial Pressure; Autonomic Nervous System; Baroreflex; Cardiovascular System; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Protective Agents; Pyridostigmine Bromide; Rats; Rats, Wistar; Stomach; Stroke Volume | 2020 |
Pyridostigmine bromide exposure creates chronic, underlying neuroimmune disruption in the gastrointestinal tract and brain that alters responses to palmitoylethanolamide in a mouse model of Gulf War Illness.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cholinesterase Inhibitors; Chronic Disease; Disease Models, Animal; Ethanolamines; Female; Gastrointestinal Tract; Male; Mice; Mice, Inbred C57BL; Neuroimmunomodulation; Palmitic Acids; Persian Gulf Syndrome; Pyridostigmine Bromide | 2020 |
Slow-binding reversible inhibitor of acetylcholinesterase with long-lasting action for prophylaxis of organophosphate poisoning.
Topics: Animals; Benzylammonium Compounds; Bromides; Cholinesterase Inhibitors; Delayed-Action Preparations; Disease Models, Animal; Mice; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Pyridostigmine Bromide; Time Factors | 2020 |
The peroxisome proliferator-activated receptor gamma (PPARγ) agonist, rosiglitazone, ameliorates neurofunctional and neuroinflammatory abnormalities in a rat model of Gulf War Illness.
Topics: Animals; Anxiety; Astrocytes; Brain; Cognition; Disease Models, Animal; Female; Hippocampus; Lipopolysaccharides; Male; Persian Gulf Syndrome; PPAR gamma; Pyridostigmine Bromide; Rats; Rats, Wistar; Rosiglitazone; Stress, Psychological | 2020 |
Pyridostigmine ameliorates preeclamptic features in pregnant rats by inhibiting tumour necrosis factor-α synthetsis and antagonizing tumour necrosis factor-α-related effects.
Topics: Acetylcholinesterase; Animals; Blood Pressure; Disease Models, Animal; Endothelial Cells; Female; Humans; Ischemia; Placenta; Pre-Eclampsia; Pregnancy; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2021 |
Exposure to Gulf War Illness-related agents leads to the development of chronic pain and fatigue.
Topics: Animals; Chlorpyrifos; Chronic Pain; DEET; Disease Models, Animal; Fatigue; Humans; Mice; Permethrin; Persian Gulf Syndrome; Pyridostigmine Bromide | 2021 |
Corticosterone primes the neuroinflammatory response to Gulf War Illness-relevant organophosphates independently of acetylcholinesterase inhibition.
Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Corticosterone; Disease Models, Animal; Gulf War; Male; Mice, Inbred C57BL; Organophosphates; Persian Gulf Syndrome; Pyridostigmine Bromide | 2017 |
Effect of pyridostigmine on in vivo and in vitro respiratory muscle of mdx mice.
Topics: Age Factors; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Drug Delivery Systems; In Vitro Techniques; Liposomes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle Contraction; Muscular Dystrophy, Duchenne; Plethysmography; Pyridostigmine Bromide; Respiration Disorders; Respiratory Muscles; Respiratory Rate; Spectrophotometry, Ultraviolet; Tidal Volume | 2017 |
Cholinergic Stimulation Improves Oxidative Stress and Inflammation in Experimental Myocardial Infarction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cardiotonic Agents; Cholinesterase Inhibitors; Cytokines; Disease Models, Animal; Hemodynamics; Inflammation; Male; Myocardial Infarction; Oxidative Stress; Pyridostigmine Bromide; Random Allocation; Rats, Wistar | 2017 |
Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.
Topics: Animals; Cells, Cultured; Cholinesterase Inhibitors; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertension, Pulmonary; Male; Organ Culture Techniques; Parasympathetic Nervous System; Pulmonary Artery; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right | 2018 |
Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease.
Topics: Acetylcholine; Animals; Anxiety; Astrocytes; Brain; DEET; Disease Models, Animal; Encephalitis; Female; gamma-Aminobutyric Acid; Male; Mice, Transgenic; Microglia; Permethrin; Persian Gulf Syndrome; Pyridostigmine Bromide; Stress, Psychological | 2018 |
Behavioral, cellular and molecular maladaptations covary with exposure to pyridostigmine bromide in a rat model of gulf war illness pain.
Topics: Adaptation, Physiological; Animals; Behavior, Animal; Chlorpyrifos; DEET; Disease Models, Animal; Ganglia, Spinal; KCNQ Potassium Channels; Male; Muscle, Skeletal; NAV1.9 Voltage-Gated Sodium Channel; Pain Perception; Pain Threshold; Permethrin; Persian Gulf Syndrome; Pyridostigmine Bromide; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction; Time Factors; TRPA1 Cation Channel | 2018 |
Pathophysiology in a model of Gulf War Illness: Contributions of pyridostigmine bromide and stress.
Topics: Animals; Brain; Cholinesterases; Corticosterone; Cytokines; Disease Models, Animal; Gulf War; Male; Memory Disorders; Persian Gulf Syndrome; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Stress, Psychological; Time Factors | 2018 |
Corticosterone and pyridostigmine/DEET exposure attenuate peripheral cytokine expression: Supporting a dominant role for neuroinflammation in a mouse model of Gulf War Illness.
Topics: Animals; Cholinesterase Inhibitors; Corticosterone; Cytokines; DEET; Disease Models, Animal; Gene Expression; Inflammation; Inflammation Mediators; Insect Repellents; Male; Mice; Mice, Inbred C57BL; Persian Gulf Syndrome; Pyridostigmine Bromide | 2019 |
Pyridostigmine alleviates cardiac dysfunction via improving mitochondrial cristae shape in a mouse model of metabolic syndrome.
Topics: Animals; Cholinesterase Inhibitors; Diet, High-Fat; Disease Models, Animal; Heart Diseases; Insulin Resistance; Male; Metabolic Syndrome; Mice; Mitochondria, Heart; Mitochondrial Membranes; Mitochondrial Proteins; Organelle Shape; Pyridostigmine Bromide | 2019 |
Cholinergic Stimulation by Pyridostigmine Bromide Before Myocardial Infarction Prevent Cardiac and Autonomic Dysfunction.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Cholinesterase Inhibitors; Disease Models, Animal; Gene Expression Regulation; Interferon-gamma; Interleukin-10; Interleukin-1beta; Interleukin-6; Male; Myocardial Infarction; Pyridostigmine Bromide; Rats; Rats, Wistar; Ventricular Function, Left | 2019 |
Pretreatment with pyridostigmine bromide has no effect on seizure behavior or 24 hour survival in the rat model of acute diisopropylfluorophosphate intoxication.
Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Disease Models, Animal; GPI-Linked Proteins; Isoflurophate; Male; Neurotoxicity Syndromes; Organophosphate Poisoning; Pyridostigmine Bromide; Rats, Sprague-Dawley; Seizures; Time Factors | 2019 |
Chronic Treatment With Acetylcholinesterase Inhibitors Attenuates Vascular Dysfunction in Spontaneously Hypertensive Rats.
Topics: Acetylcholinesterase; Animals; Antihypertensive Agents; Arterial Pressure; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; GPI-Linked Proteins; Hemodynamics; Hypertension; Mesenteric Arteries; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Pyridostigmine Bromide; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Vascular Resistance; Vasoconstriction; Vasodilation | 2019 |
Pyridostigmine bromide and stress interact to impact immune function, cholinergic neurochemistry and behavior in a rat model of Gulf War Illness.
Topics: Acetylcholine; Animals; Behavior, Animal; C-Reactive Protein; Cholinesterase Inhibitors; Conditioning, Classical; Disease Models, Animal; Fear; Hippocampus; Inflammation; Lipopolysaccharides; Male; Persian Gulf Syndrome; Prefrontal Cortex; Pyridostigmine Bromide; Rats, Sprague-Dawley; Stress, Psychological | 2019 |
Neuroinflammation in Gulf War Illness is linked with HMGB1 and complement activation, which can be discerned from brain-derived extracellular vesicles in the blood.
Topics: Animals; Astrocytes; Brain; Complement Activation; Cytokines; DEET; Disease Models, Animal; Encephalitis; Extracellular Vesicles; Gulf War; HMGB1 Protein; Inflammation; Male; Neuroimmunomodulation; Neurons; Permethrin; Persian Gulf Syndrome; Pyridostigmine Bromide; Rats | 2019 |
A permethrin metabolite is associated with adaptive immune responses in Gulf War Illness.
Topics: Adaptive Immunity; Adult; Animals; Benzoates; Brain; Central Nervous System; Disease Models, Animal; Female; Gulf War; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Permethrin; Persian Gulf Syndrome; Pyridostigmine Bromide; Veterans | 2019 |
Mood and memory deficits in a model of Gulf War illness are linked with reduced neurogenesis, partial neuron loss, and mild inflammation in the hippocampus.
Topics: Animals; Anxiety; Cell Death; Cholinesterase Inhibitors; DEET; Depression; Disease Models, Animal; Hippocampus; Inflammation; Insect Repellents; Insecticides; Memory Disorders; Mood Disorders; Neurogenesis; Neurons; Permethrin; Persian Gulf Syndrome; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Stress, Psychological; Swimming | 2013 |
Parasympathetic activation by pyridostigmine on chemoreflex sensitivity in heart-failure rats.
Topics: Animals; Cholinesterase Inhibitors; Disease Models, Animal; Heart Failure; Heart Rate; Hypercapnia; Hypoxia; Male; Parasympathetic Nervous System; Pulmonary Ventilation; Pyridostigmine Bromide; Rats; Rats, Wistar | 2013 |
Arterial baroreflex dysfunction impairs ischemia-induced angiogenesis.
Topics: Animals; Arteries; Baroreflex; Cholinesterase Inhibitors; Disease Models, Animal; Extremities; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemia; Male; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; Pyridostigmine Bromide; Rats, Sprague-Dawley; Signal Transduction; Vascular Endothelial Growth Factor A | 2014 |
Pyridostigmine prevents haemodynamic alterations but does not affect their nycthemeral oscillations in infarcted mice.
Topics: Animals; Arterial Pressure; Cholinesterase Inhibitors; Circadian Rhythm; Disease Models, Animal; Heart Rate; Hemodynamics; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Pyridostigmine Bromide; Telemetry | 2015 |
Gulf War agent exposure causes impairment of long-term memory formation and neuropathological changes in a mouse model of Gulf War Illness.
Topics: Animals; Astrocytes; Cerebral Cortex; Cognition; Disease Models, Animal; Gene Expression; Gulf War; Hippocampus; Humans; Male; Memory, Long-Term; Memory, Short-Term; Mice; Mice, Inbred C57BL; Permethrin; Persian Gulf Syndrome; Pyridostigmine Bromide; Synaptophysin; Time Factors | 2015 |
A delayed chronic pain like condition with decreased Kv channel activity in a rat model of Gulf War Illness pain syndrome.
Topics: Animals; Chlorpyrifos; Cholinesterase Inhibitors; Chronic Pain; Delayed Rectifier Potassium Channels; Disease Models, Animal; Ganglia, Spinal; KCNQ1 Potassium Channel; Male; Membrane Potentials; Nociceptors; Pain Threshold; Permethrin; Persian Gulf Syndrome; Potassium Channels, Voltage-Gated; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley | 2015 |
Chronic cholinergic stimulation promotes changes in cardiovascular autonomic control in spontaneously hypertensive rats.
Topics: Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Cholinesterase Inhibitors; Disease Models, Animal; Heart Rate; Hypertension; Male; Pyridostigmine Bromide; Rats, Inbred SHR; Rats, Inbred WKY; Stroke Volume; Vagus Nerve | 2015 |
Increase in cholinergic modulation with pyridostigmine induces anti-inflammatory cell recruitment soon after acute myocardial infarction in rats.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Blood Pressure; CD8-Positive T-Lymphocytes; Chemotaxis, Leukocyte; Cholinergic Neurons; Cholinesterase Inhibitors; Disease Models, Animal; Forkhead Transcription Factors; Heart Rate; Interleukin-2 Receptor alpha Subunit; Macrophage Activation; Macrophages; Male; Myocardial Infarction; Myocardium; Phenotype; Pyridostigmine Bromide; Rats, Inbred WKY; Spleen; T-Lymphocytes, Regulatory; Time Factors; Ventricular Function, Left | 2016 |
Exposure to Gulf War Illness chemicals induces functional muscarinic receptor maladaptations in muscle nociceptors.
Topics: Animals; Chemical Warfare Agents; Chlorpyrifos; Chronic Pain; Disease Models, Animal; Ganglia, Spinal; Gene Expression Regulation; Male; Membrane Potentials; Muscarinic Agonists; Muscle, Skeletal; Neurons; Nociceptors; Pain Threshold; Permethrin; Potassium Channel Blockers; Potassium Channels; Pyridostigmine Bromide; Rats; Receptors, Muscarinic | 2016 |
Long-term epigenetic alterations in a rat model of Gulf War Illness.
Topics: Animals; Apoptosis; Brain; Cytokines; Disease Models, Animal; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Epigenesis, Genetic; Fluoresceins; Gene Expression Regulation; In Situ Nick-End Labeling; Male; MicroRNAs; Permethrin; Persian Gulf Syndrome; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2016 |
A rodent model of human organophosphate exposure producing status epilepticus and neuropathology.
Topics: Animals; Antidotes; Atropine; Central Nervous System Diseases; Cholinesterase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Male; Organophosphates; Phosphoric Triester Hydrolases; Pralidoxime Compounds; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2016 |
Gulf War illness: Effects of repeated stress and pyridostigmine treatment on blood-brain barrier permeability and cholinesterase activity in rat brain.
Topics: Acetylcholinesterase; Animals; Autoradiography; Avoidance Learning; Blood-Brain Barrier; Brain; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Disease Models, Animal; Erythrocytes; Male; Permeability; Persian Gulf Syndrome; Pyridostigmine Bromide; Radioimmunoassay; Rats; Stress, Physiological | 2009 |
Continuous administration of pyridostigmine improves immobilization-induced neuromuscular weakness.
Topics: Animals; Atracurium; Cholinesterase Inhibitors; Disease Models, Animal; Hindlimb; Immobilization; Infusion Pumps; Infusions, Subcutaneous; Male; Muscle Contraction; Muscle Strength; Muscle Weakness; Muscular Atrophy; Neuromuscular Junction; Neuromuscular Nondepolarizing Agents; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic | 2010 |
Technical report: exploring the basis of congenital myasthenic syndromes in an undergraduate course, using the model organism, Caenorhabditis elegans.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cholinesterase Inhibitors; Disease Models, Animal; Education, Medical, Undergraduate; Mutation; Myasthenic Syndromes, Congenital; Pyridostigmine Bromide; Receptors, Nicotinic | 2010 |
Cholinesterase inhibitors and stress: effects on brain muscarinic receptor density in mice.
Topics: Animals; Brain; Cholinesterase Inhibitors; Cholinesterases; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Physostigmine; Protein Binding; Pyridostigmine Bromide; Receptors, Muscarinic; Stress, Psychological | 2010 |
A Cys-loop mutation in the Caenorhabditis elegans nicotinic receptor subunit UNC-63 impairs but does not abolish channel function.
Topics: 4-Aminopyridine; Amifampridine; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cholinesterase Inhibitors; Disease Models, Animal; Gene Expression Regulation; Humans; Muscles; Mutation; Myasthenic Syndromes, Congenital; Neuromuscular Junction; Potassium Channel Blockers; Protein Structure, Secondary; Pyridostigmine Bromide; Receptors, Nicotinic; Swimming | 2011 |
Impaired neuromuscular transmission and response to acetylcholinesterase inhibitors in centronuclear myopathies.
Topics: Adolescent; Animals; Biopsy; Child; Cholinesterase Inhibitors; Disease Models, Animal; Electromyography; Female; Gene Knockout Techniques; Humans; Infant; Male; Muscle, Skeletal; Myopathies, Structural, Congenital; Neuromuscular Junction; Protein Tyrosine Phosphatases, Non-Receptor; Pyridostigmine Bromide; Synaptic Transmission; Treatment Outcome; Zebrafish; Zebrafish Proteins | 2011 |
Myotubular myopathy and the neuromuscular junction: a novel therapeutic approach from mouse models.
Topics: Animals; Cell Membrane; Disease Models, Animal; Gene Expression Regulation; Mice; Mice, Knockout; Motor Activity; Myopathies, Structural, Congenital; Neuregulin-1; Neuromuscular Junction; Phenotype; Pyridostigmine Bromide; Receptors, Cholinergic; Signal Transduction; Synaptic Transmission | 2012 |
Lipidomic profiling of phosphocholine-containing brain lipids in mice with sensorimotor deficits and anxiety-like features after exposure to Gulf War agents.
Topics: Animals; Anxiety; Ataxia; Brain Chemistry; Cerebral Cortex; DEET; Dentate Gyrus; Disease Models, Animal; Exploratory Behavior; Fatty Acids; Female; Gliosis; Male; Maze Learning; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Permethrin; Peroxisomes; Persian Gulf Syndrome; Phosphatidylcholines; Psychomotor Performance; Pyridostigmine Bromide; Random Allocation; Rotarod Performance Test; Sensation Disorders; Sphingomyelins; Stearoyl-CoA Desaturase | 2012 |
Neuromuscular junction abnormalities in DNM2-related centronuclear myopathy.
Topics: Adult; Animals; Child; Cholinesterase Inhibitors; Disease Models, Animal; Dynamin II; Female; Humans; Male; Motor Activity; Muscle Weakness; Muscle, Skeletal; Myopathies, Structural, Congenital; Neuromuscular Junction; Pyridostigmine Bromide; Young Adult; Zebrafish | 2013 |
Evaluation of immunotoxicity induced by single or concurrent exposure to N,N-diethyl-m-toluamide (DEET), pyridostigmine bromide (PYR), and JP-8 jet fuel.
Topics: Animals; Cholinesterase Inhibitors; DEET; Disease Models, Animal; Drug Interactions; Female; Hydrocarbons; Hypersensitivity, Delayed; Immune System; Insect Repellents; Mice; Persian Gulf Syndrome; Pyridostigmine Bromide | 2001 |
Stress and combined exposure to low doses of pyridostigmine bromide, DEET, and permethrin produce neurochemical and neuropathological alterations in cerebral cortex, hippocampus, and cerebellum.
Topics: Animals; Cerebellum; Cerebral Cortex; Cholinesterase Inhibitors; Cognition Disorders; DEET; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Humans; Insect Repellents; Movement Disorders; Persian Gulf Syndrome; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2004 |
Effects of fosphenytoin on nerve agent-induced status epilepticus.
Topics: Animals; Anticonvulsants; Atropine; Chemical Warfare Agents; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Injections, Intraperitoneal; Male; Phenytoin; Pralidoxime Compounds; Pyridostigmine Bromide; Soman; Status Epilepticus | 2004 |
The anti-inflammatory and cholinesterase inhibitor bifunctional compound IBU-PO protects from beta-amyloid neurotoxicity by acting on Wnt signaling components.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Brain; Cells, Cultured; Cholinesterase Inhibitors; Cytoskeletal Proteins; Disease Models, Animal; Down-Regulation; Drug Compounding; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Ibuprofen; Intercellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Neuroprotective Agents; Peptide Fragments; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Signal Transduction; Trans-Activators; Wnt Proteins | 2005 |
Extrapolating from animal studies to the efficacy in humans of a pretreatment combination against organophosphate poisoning.
Topics: Animals; Chemical Warfare Agents; Cholinergic Antagonists; Cyclopentanes; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Infusions, Parenteral; Lethal Dose 50; Male; Metabolic Clearance Rate; Organophosphate Poisoning; Organophosphates; Papio anubis; Poisoning; Pyridostigmine Bromide; Sarin; Species Specificity; Treatment Outcome | 2007 |
Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication.
Topics: Animals; Anticonvulsants; Atropine; Biperiden; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Seizures; Soman | 2000 |
Neither forced running nor forced swimming affect acute pyridostigmine toxicity or brain-regional cholinesterase inhibition in rats.
Topics: Administration, Oral; Animals; Blood-Brain Barrier; Brain; Cholinesterase Inhibitors; Cholinesterases; Corticosterone; Disease Models, Animal; Exercise Test; Horseradish Peroxidase; Male; Physical Exertion; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Running; Stress, Physiological; Swimming | 2002 |