pyridinoline has been researched along with Disease Exacerbation in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 15 (62.50) | 29.6817 |
| 2010's | 5 (20.83) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavet, G; Huizinga, TW; Knevel, R; Krabben, A; van der Helm-van Mil, AH | 1 |
| Alivernini, S; Ferraccioli, G; Gremese, E | 1 |
| Garnero, P; Hashimoto, J; Kawai, S; Miyasaka, N; Nishimoto, N; Takeuchi, T; van der Heijde, D; Yamamoto, K; Yoshikawa, H | 2 |
| Doi, M; Nagano, A; Sarukawa, J; Suzuki, D; Takahashi, M | 1 |
| Chen, Y; Cui, L; Li, SF; Ren, L; Tong, ZS; Wang, C; Wang, XR | 1 |
| Boumier, P; Brazier, M; Daragon, A; Fardellone, P; Gayet, A; Le Loët, X; Mejjad, O; Menard, JF; Pouplin, S; Tron, F; Vittecoq, O; Zarnitsky, C | 1 |
| Alexandrakis, MG; Katachanakis, C; Kyriakou, DS; Malliaraki, N; Margioris, AN; Passam, FH | 1 |
| Bruyere, O; Collette, JH; Ethgen, O; Giacovelli, G; Henrotin, YE; Reginster, JY; Rovati, LC; Seidel, L | 1 |
| Açil, Y; Dunsche, A; Springer, IN; Suhr, MA; Terheyden, H; Tiemann, M; Warnke, P | 1 |
| Abe, M; Nagano, A; Naito, K; Sawada, T; Takahashi, M | 1 |
| Hirayama, Y; Imamura, Y; Imanishi, J; Ishikawa, T; Minoura, K; Miyata, S; Mizutani, T; Mutoh, S; Neya, M; Nishigaki, F; Ohkubo, Y | 1 |
| Collette, J; Deberg, MA; Henrotin, YE; Labasse, AH; Reginster, JY; Seidel, L | 1 |
| Cawston, T; Christgau, S; Coady, D; Griffiths, I; Marshall, N; Robins, S; Saxne, T; Young-Min, S | 1 |
| Kapoor, S | 1 |
| Hein, G; Müller, A; Schmidt, WA; Stiehl, P; Voigt, A; Wernicke, D | 1 |
| Arai, K; Miura, M; Saitoh, H; Takeuchi, S; Yoshida, K | 1 |
| Chavarria, AE; Glasson, SS; Haimes, HB; Harlan, PM; Jimenez, PA; Trubetskoy, OV | 1 |
| Heersche, JN; Iwayama, Y; Murahashi, Y; Shibutani, T; Tsukada, E | 1 |
| Assiri, A; Bundred, NJ; Eastell, R; Howell, A; Ratcliffe, WA; Rogers, E; Walls, J | 1 |
| Goto, S; Ishihara, C; Kushida, K; Murata, H; Nagano, A; Ohishi, T; Takahashi, M | 1 |
| Clark, RE; Durham, BH; Flory, AJ; Fraser, WD; Ion, EM; Woodcock, BE | 1 |
| Eun, SS; Hasegawa, C; Ikai, T; Kimura, C; Miyano, S; Uematsu, M | 1 |
| Cochran, DL; Graves, DT; Oates, TW | 1 |
5 trial(s) available for pyridinoline and Disease Exacerbation
| Article | Year |
|---|---|
A combination of biochemical markers of cartilage and bone turnover, radiographic damage and body mass index to predict the progression of joint destruction in patients with rheumatoid arthritis treated with disease-modifying anti-rheumatic drugs.
Topics: Aged; Amino Acids; Antirheumatic Agents; Arthritis, Rheumatoid; Arthrography; Biomarkers; Collagen Type II; Disease Progression; Female; Humans; Male; Middle Aged; Severity of Illness Index | 2009 |
Humanized anti-interleukin-6-receptor antibody (tocilizumab) monotherapy is more effective in slowing radiographic progression in patients with rheumatoid arthritis at high baseline risk for structural damage evaluated with levels of biomarkers, radiograp
Topics: Amino Acids; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Body Mass Index; Collagen Type I; Disease Progression; Humans; Joints; Peptides; Prospective Studies; Treatment Outcome | 2011 |
Biomarkers predict radiographic progression in early rheumatoid arthritis and perform well compared with traditional markers.
Topics: Adult; Aged; Amino Acids; Arthritis, Rheumatoid; Biomarkers; Cartilage Oligomeric Matrix Protein; Collagen Type II; Disease Progression; Extracellular Matrix Proteins; Female; Glycoproteins; Humans; Male; Matrilin Proteins; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; Matrix Metalloproteinases; Middle Aged; Predictive Value of Tests; Radiography; Time Factors; Tissue Inhibitor of Metalloproteinase-1 | 2007 |
The efficacy of biochemical markers in patients with ossification of posterior longitudinal ligament of the spine.
Topics: Aged; Amino Acids; Biomarkers; Collagen; Collagen Type I; Disease Progression; Humans; Male; Middle Aged; Ossification of Posterior Longitudinal Ligament; Osteocalcin; Peptide Fragments; Peptides; Predictive Value of Tests; Procollagen; Reference Values | 2000 |
Prevention of secondary osteoporosis postmenopause in hemiplegia.
Topics: Absorptiometry, Photon; Activities of Daily Living; Aged; Alkaline Phosphatase; Amino Acids; Bone Density; Disease Progression; Etidronic Acid; Female; Follow-Up Studies; Geriatric Assessment; Hemiplegia; Humans; Osteocalcin; Osteoporosis, Postmenopausal; Radionuclide Imaging | 2001 |
19 other study(ies) available for pyridinoline and Disease Exacerbation
| Article | Year |
|---|---|
Serum pyridinoline levels and prediction of severity of joint destruction in rheumatoid arthritis.
Topics: Adult; Aged; Amino Acids; Arthritis, Rheumatoid; Biomarkers; Cohort Studies; Disease Progression; Female; Follow-Up Studies; Humans; Joints; Longitudinal Studies; Male; Middle Aged; Predictive Value of Tests; Prognosis; Regression Analysis; Sensitivity and Specificity; Severity of Illness Index | 2013 |
Biomarkers of joint damage in rheumatoid arthritis: where are we in 2013?
Topics: Amino Acids; Arthritis, Rheumatoid; Disease Progression; Female; Humans; Joints; Male; Severity of Illness Index | 2013 |
A longitudinal analysis of urinary biochemical markers and bone mineral density in STR/Ort mice as a model of spontaneous osteoarthritis.
Topics: Absorptiometry, Photon; Amino Acids; Animals; Biomarkers; Body Weight; Bone Density; Collagen Type I; Disease Models, Animal; Disease Progression; Early Diagnosis; Femur; Knee Joint; Male; Mice; Mice, Inbred CBA; Osteoarthritis; Peptide Fragments; Peptides; Procollagen | 2010 |
[Relationship of osteolytic biochemical indicators of bone metabolism with the therapeutic effect in breast cancer patients with bone metastases].
Topics: Adult; Aged; Amino Acids; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Collagen; Collagen Type I; Disease Progression; Female; Follow-Up Studies; Humans; Middle Aged; Peptides; Remission Induction | 2009 |
Serum IgA rheumatoid factor and pyridinoline in very early arthritis as predictors of erosion(s) at two years: a simple model of prediction from a conservatively treated community-based inception cohort.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Antirheumatic Agents; Arthritis, Rheumatoid; Disease Progression; Female; Follow-Up Studies; Humans; Immunoglobulin A; Male; Middle Aged; Prognosis; Prospective Studies; Rheumatoid Factor; Severity of Illness Index; Surveys and Questionnaires; Time Factors; Young Adult | 2010 |
Evaluation of bone disease in multiple myeloma: a correlation between biochemical markers of bone metabolism and other clinical parameters in untreated multiple myeloma patients.
Topics: Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Remodeling; Case-Control Studies; Collagen; Collagen Type I; Disease Progression; Female; Humans; Male; Multiple Myeloma; Neoplasm Staging; Osteocalcin; Osteolysis; Peptides; Severity of Illness Index | 2002 |
Biochemical markers of bone and cartilage remodeling in prediction of longterm progression of knee osteoarthritis.
Topics: Aged; Amino Acids; Biomarkers; Bone and Bones; Cartilage; Cartilage Oligomeric Matrix Protein; Disease Progression; Extracellular Matrix Proteins; Female; Glycoproteins; Humans; Hyaluronic Acid; Keratan Sulfate; Longitudinal Studies; Male; Matrilin Proteins; Middle Aged; Osteoarthritis, Knee; Osteocalcin; Predictive Value of Tests; Radiography | 2003 |
Follow-up of collagen crosslink excretion in patients with oral squamous cell carcinoma and analysis of tissue samples.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Biomarkers, Tumor; Carcinoma, Squamous Cell; Collagen; Disease Progression; Female; Humans; Male; Mandibular Neoplasms; Middle Aged; Mouth Neoplasms | 2003 |
Relationship between radiographic grading of osteoarthritis and the biochemical markers for arthritis in knee osteoarthritis.
Topics: Adipokines; Aged; Aged, 80 and over; Amino Acids; Biomarkers; C-Reactive Protein; Chitinase-3-Like Protein 1; Disease Progression; Female; Glycoproteins; Hand; Humans; Lectins; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Middle Aged; Osteoarthritis; Osteoarthritis, Knee; Postmenopause; Radiography; Spinal Osteophytosis; Tissue Inhibitor of Metalloproteinase-1 | 2004 |
Prevention of progressive joint destruction in adjuvant induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR217840.
Topics: Acid Phosphatase; Amino Acids; Animals; Ankle Joint; Arthritis, Experimental; Cell Line; Cells, Cultured; Collagenases; Disease Progression; Female; Humans; Isoenzymes; Joint Diseases; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 8; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Piperazines; Protease Inhibitors; Radiography; Rats; Rats, Inbred Lew; Tartrate-Resistant Acid Phosphatase; Tumor Necrosis Factor-alpha | 2005 |
One-year increase of Coll 2-1, a new marker of type II collagen degradation, in urine is highly predictive of radiological OA progression.
Topics: Aged; Amino Acids; Biomarkers; Cartilage, Articular; Collagen Type II; Disability Evaluation; Disease Progression; Female; Follow-Up Studies; Humans; Immunoassay; Knee Joint; Male; Middle Aged; Osteoarthritis, Knee; Peptide Fragments; Predictive Value of Tests; Radiographic Image Interpretation, Computer-Assisted | 2005 |
TGF-beta 1 and urinary excretion of pyridinium crosslinks: Two often overlooked risk factors for assessing risk of progression in patients with monoclonal gammopathy of undetermined significance.
Topics: Amino Acids; Bone Resorption; Diagnosis, Differential; Disease Progression; Humans; Multiple Myeloma; Paraproteinemias; Risk Factors; Transforming Growth Factor beta1; Ultrasonography | 2008 |
[Association between histopathologic type II synovitis and increased amounts of pyridinoline in synovial tissue samples in rheumatoid arthritis].
Topics: Adult; Aged; Amino Acids; Arthritis, Rheumatoid; B-Lymphocytes; Cartilage, Articular; Cohort Studies; Collagen; Disease Progression; Female; Humans; Macrophages; Male; Middle Aged; Synovial Membrane; Synovitis; T-Lymphocytes | 2008 |
Urinary pyridinoline and deoxypyridinoline as potential markers of bone metastasis in patients with prostate cancer.
Topics: Aged; Alkaline Phosphatase; Amino Acids; Biomarkers, Tumor; Bone Neoplasms; Disease Progression; Humans; Male; Osteocalcin; Predictive Value of Tests; Prostatic Hyperplasia; Prostatic Neoplasms; Treatment Outcome; Ultrasonography | 1996 |
Blotchy mice: a model of osteoarthritis associated with a metabolic defect.
Topics: Aging; Amino Acids; Animals; Aortic Rupture; Cartilage, Articular; Collagen; Collagen Diseases; Disease Models, Animal; Disease Progression; Elastin; Enzyme-Linked Immunosorbent Assay; Female; Femur; Male; Mice; Mice, Inbred C57BL; Osteoarthritis; Protein-Lysine 6-Oxidase; Stifle; Tibia | 1996 |
Experimentally induced periodontitis in beagle dogs causes rapid increases in osteoclastic resorption of alveolar bone.
Topics: Acid Phosphatase; Alveolar Bone Loss; Alveolar Process; Amino Acids; Animals; Biomarkers; Cell Differentiation; Coloring Agents; Connective Tissue; Cross-Linking Reagents; Disease Progression; Dogs; Enzyme-Linked Immunosorbent Assay; Female; Giant Cells; Gingiva; Gingival Crevicular Fluid; Histocytochemistry; Isoenzymes; Leukocytes, Mononuclear; Male; Osteoclasts; Periodontal Ligament; Periodontitis; Pyridinium Compounds; Tartrate-Resistant Acid Phosphatase | 1997 |
Measurement of urinary collagen cross-links indicate response to therapy in patients with breast cancer and bone metastases.
Topics: Adult; Aged; Amino Acids; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Cross-Linking Reagents; Disease Progression; Estrogen Antagonists; Female; Humans; Middle Aged; Prospective Studies | 1999 |
Biochemical markers of bone turnover following high-dose chemotherapy and autografting in multiple myeloma.
Topics: Adult; Aged; Alkaline Phosphatase; Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Bone Remodeling; Bone Resorption; Carmustine; Clodronic Acid; Combined Modality Therapy; Cytarabine; Disease Progression; Female; Hematopoietic Stem Cell Transplantation; Humans; Isoenzymes; Male; Melphalan; Middle Aged; Multiple Myeloma; Osteoclasts; Peptide Fragments; Podophyllotoxin; Procollagen; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome | 2000 |
Clinical, radiographic and biochemical assessment of IL-1/TNF-alpha antagonist inhibition of bone loss in experimental periodontitis.
Topics: Alkaline Phosphatase; Alveolar Bone Loss; Amino Acids; Analysis of Variance; Animals; Biomarkers; Bone Density; Disease Models, Animal; Disease Progression; Gingival Crevicular Fluid; Gingivitis; Image Processing, Computer-Assisted; Interleukin-1; Macaca fascicularis; Periodontal Index; Periodontitis; Pharmaceutical Vehicles; Porphyromonas gingivalis; Radiography; Receptors, Interleukin-1; Receptors, Tumor Necrosis Factor; Statistics as Topic; Statistics, Nonparametric; Subtraction Technique; Tumor Necrosis Factor-alpha | 2002 |