Page last updated: 2024-08-26

pyridinoline and Aging

pyridinoline has been researched along with Aging in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (16.22)	18.7374
1990's	44 (59.46)	18.2507
2000's	14 (18.92)	29.6817
2010's	4 (5.41)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brozek, W; Cohen, A; Dempster, D; Eriksen, EF; Fratzl, P; Gamsjaeger, S; Glorieux, FH; Hassler, N; Klaushofer, K; Paschalis, EP; Rauch, F; Recker, R; Shane, E	1
Bank, RA; Deemter, Mv; Hooymans, JM; Los, LI; Ponsioen, TL; Snabel, JM; van der Worp, RJ; Zijlstra, GS	1
Aagaard, P; Couppé, C; Hansen, P; Kjaer, M; Kongsgaard, M; Kovanen, V; Magnusson, SP; Suetta, C	1
Jurvelin, JS; Karjalainen, HM; Kokkonen, HT; Korhonen, RK; Kovanen, V; Kulmala, KA; Mäkelä, J; Rieppo, L; Tiitu, V; Töyräs, J	1
Andrillo-Sanchez, M; Cashman, KD; Ciarapica, D; Coudray, C; Hill, TR; Hininger-Favier, I; Meunier, N; O Connor, JM; Polito, A; Scully, L; Seamans, KM; Simpson, EE; Stewart-Knox, BJ	1
Berezovs'kyĭ, VIa; Ianko, RV; Litovka, IH; Zamors'ka, TM	1
Denbow, DM; Liu, D; Veit, HP; Wilson, JH	1
Edmondston, SJ; Kent, GN; Randall, AG; Singer, KP; Tan, CI	1
Chen, AC; Masuda, K; Sah, RL; Thonar, EJ; Williamson, AK	1
Frausto, A; Gruber, HE; Mills, BG; Norton, HJ; Rude, RK; Wei, LY	1
Pietryla, DW; Thonar, EJ; Uebelhart, D; Williams, JM	1
Blaydes, B; Delclos, KB; Hotchkiss, CE; Newbold, R; Weis, C	1
Andriollo-Sanchez, M; Cashman, KD; Ciarapica, D; Coudray, C; Hill, T; Hininger-Favier, I; Meunier, N; O'Connor, JM; Polito, A	1
Charbeneau, RA; Klunzinger, MW; Orth, MW; Roberson, KD	1
Carrithers, JA; Haus, JM; Trappe, SW; Trappe, TA	1
Robins, SP	1
Fujimoto, D	2
Fujimoto, D; Inoue, T; Miyamoto, S; Suzuki, M; Uchiyama, A	1
Jha, M	1
Deyl, Z; Horáková, M; Vanciková, O	1
Fujimoto, D; Inoue, T; Uchiyama, A	1
Higuchi, K; Shimizu, K; Takeda, T; Yamamuro, T	1
Akesson, K	1
Duncan, A; Leidig-Bruckner, G; Nicol, P; Robins, SP; Scheidt-Nave, C; Seibel, MJ; Woitge, H; Ziegler, R	1
Boja, B; Monnier, V; Moskowitz, RW; Pokharna, HK	1
Gosselin, LE; Martinez, DA; Sieck, GC; Vailas, AC	1
Arakawa, N; Kim, M; Otsuka, M	1
Nagata, M; Nemoto, S; Yoshihara, K	1
Hata, K; Miura, M	1
Rauch, F; Remer, T; Schönau, E; Seibel, M; Woitge, H	1
Hoshino, H; Inoue, T; Kawana, K; Kushida, K; Ohishi, T; Takahashi, M; Uchiyama, A	1
Aoshima, H; Horiuchi, K; Hoshino, H; Inoue, T; Kawana, K; Kushida, K; Ohishi, T; Takahashi, M	1
Barlet, JP; Braillon, P; Coxam, V; Davicco, MJ; Delmas, PD; Gaumet, N; Giry, J; Lebecque, P; Rouffet, J; Seibel, MJ	1
Atley, LM; Burger, HG; Dennerstein, L; Ebeling, PR; Guthrie, JR; Hopper, JL; Wark, JD	1
Chapuy, MC; Delmas, PD; Garnero, P; Sornay-Rendu, E	1
Bailey, AJ; Oxlund, H; Rasmussen, LM; Sims, TJ	1
Kenny, AM; Pannullo, AM; Pilbeam, CC; Prestwood, KM; Raisz, LG	1
Chavarria, AE; Glasson, SS; Haimes, HB; Harlan, PM; Jimenez, PA; Trubetskoy, OV	1
Kobylińska, M; Lorenc, RS; Lukaszkiewicz, J; Marowska, J; Rymkiewicz-Kluczyńska, B; Tałajko, A	1
Colwell, A; Eastell, R	1
Gillis, C; Meagher, DM; Pool, RR; Reiser, K; Stover, SM; Willits, N	1
Nagura, H; Sawai, T; Suyama, K; Watanabe, M	1
Brüel, A; Oxlund, H	1
Brenner, M; Krebs, NF; Reidinger, CJ; Robertson, AD	1
Fujii, K; Ishioka, N; Marumo, K; Saito, M	1
Fujisawa, K; Hata, K; Mayumi, M; Miura, M; Takeuchi, M; Tsukahara, H; Yamamoto, K	1
Bailey, AJ; Knott, L	1
Bernard-Poenaru, O; Boitte, F; Brazier, M; Cohen-Solal, ME; De Vernejoul, MC; Denne, MA; Graulet, AM	1
Arakawa, N; Kim, M; Otsuka, M; Shimamura, E	1
Phillips, FM; Pokharna, HK	1
Brüel, A; Ortoft, G; Oxlund, H	1
Abbiati, G; Bellini, A; Chiumello, G; de Poli, SC; Mora, S; Prinster, C; Proverbio, MC; Weber, G	1
Black, A; Ralston, SL; Schoknecht, PA; Shapses, SA	1
Bank, RA; Hazleman, BL; Oostingh, G; Riley, GP; TeKoppele, JM	1
Kent, N; Randall, D; Singer, KP; Tan, C	1
Currey, JD; Hamer, AJ; Zioupos, P	1
Bailey, AJ; Bailey, JV; Birch, HL; Goodship, AE	1
Aguado, P; Bernad, M; Carrera, F; Del Campo, MT; González-Casaus, ML; Martínez, ME	1
Borel, O; Cloos, PA; Delmas, PD; Garnero, P; Gineyts, E; Grimaud, L	1
Bank, RA; Barneveld, A; Brama, PA; Tekoppele, JM; van Weeren, PR	1
Cotter, TA; Gosselin, LE; Li, X; McCormick, RJ; Thomas, DP	1
Arai, K; Chikuda, M; Matsumoto, Y; Takahashi, M	1
Branca, F; Golden, MH; Robins, S; Valtueña, S	1
Abe, E; Fujie, M; Fujimoto, D; Suda, T	1
Gosselin, LE; McCormick, RJ; Thomas, DP; Vadlamudi, RK; Zimmerman, SD	1
Duncan, A; Kovanen, V; Palokangas, H; Robins, SP	1
Bhatia, H; Kollerup, G; Sørensen, OH; Thamsborg, G	1
Fujie, M; Horiuchi, K; Inoue, T; Kushida, K; Ohishi, T; Takahashi, M; Uchiyama, A	1
Del'vig, AA; Gorokhova, TA; Kozlov, EA; Muranov, SG; Prozorovskaia, NN; Voronov, AV	1
Beardsworth, LJ; Dickson, IR; Eyre, DR	1
Monnier, VM; Sell, DR	1
Maynard, JA; Pedrini, VA; Pedrini-Mille, A; Vailas, AC	1
Fujimoto, D; Hiramatsu, M; Masumizu, T; Shikata, H; Utsumi, N	1

Reviews

3 review(s) available for pyridinoline and Aging

Article	Year
Analysis of the crosslinking components in collagen and elastin. Methods of biochemical analysis, 1982, Volume: 28 Topics: Aging; Amino Acids; Animals; Bone and Bones; Borohydrides; Buffers; Cartilage; Chemical Fractionation; Chemical Phenomena; Chemistry; Chromatography; Collagen; Cyanides; Drug Stability; Elastin; Glycosides; Hexoses; Hydrogen-Ion Concentration; Hydrolysis; Hydroxylysine; Lysine; Mass Spectrometry; Oxidation-Reduction; Periodic Acid; Schiff Bases; Skin	1982
Biochemical markers of bone turnover. A review. Acta orthopaedica Scandinavica, 1995, Volume: 66, Issue:4 Topics: Adult; Aged; Aging; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Diseases; Bone Remodeling; Child; Collagen; Extracellular Matrix Proteins; Female; Fractures, Bone; Humans; Hydroxyproline; Middle Aged; Osteocalcin; Peptide Fragments; Procollagen	1995
Collagen cross-links in mineralizing tissues: a review of their chemistry, function, and clinical relevance. Bone, 1998, Volume: 22, Issue:3 Topics: Aging; Amino Acids; Animals; Bone and Bones; Bone Development; Calcification, Physiologic; Collagen; Glycosylation; Humans; Hydroxylation; Hydroxylysine; Lysine; Osteoporosis; Protein-Lysine 6-Oxidase	1998

Trials

5 trial(s) available for pyridinoline and Aging

Article	Year
The relationship between the zinc nutritive status and biochemical markers of bone turnover in older European adults: the ZENITH study. European journal of clinical nutrition, 2005, Volume: 59 Suppl 2 Topics: Aged; Aged, 80 and over; Aging; Alkaline Phosphatase; Amino Acids; Biomarkers; Chromatography, High Pressure Liquid; Diet Records; Enzyme-Linked Immunosorbent Assay; Europe; Female; Humans; Male; Middle Aged; Nutrition Surveys; Nutritional Status; Osteocalcin; Osteoporosis; Prospective Studies; Spectrophotometry, Atomic; Zinc	2005
Evaluation of phytase concentration needed for growing-finishing commercial turkey toms. British poultry science, 2005, Volume: 46, Issue:4 Topics: 6-Phytase; Aging; Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Bone and Bones; Diet; Dose-Response Relationship, Drug; Male; Nutritional Requirements; Osteocalcin; Phosphorus, Dietary; Turkeys; Weight Gain	2005
Urinary hydroxypyridinium crosslinks of collagen in population-based screening for overt vertebral osteoporosis: results of a pilot study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1994, Volume: 9, Issue:9 Topics: Aged; Aged, 80 and over; Aging; Amino Acids; Bone Resorption; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Osteoporosis; Pilot Projects; ROC Curve; Sex Factors; Spinal Fractures; Spine	1994
The effect of a short course of calcium and vitamin D on bone turnover in older women. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1996, Volume: 6, Issue:4 Topics: Aged; Aging; Amino Acids; Bone and Bones; Calcium; Estrogen Replacement Therapy; Female; Humans; Parathyroid Hormone; Time Factors; Vitamin D	1996
The renal clearance of free and conjugated pyridinium cross-links of collagen. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1996, Volume: 11, Issue:12 Topics: Adolescent; Aging; Amino Acids; Child; Chromatography, High Pressure Liquid; Collagen; Female; Humans; Kidney; Macromolecular Substances; Male; Metabolic Clearance Rate; Middle Aged; Premenopause; Sensitivity and Specificity	1996

Other Studies

66 other study(ies) available for pyridinoline and Aging

Article	Year
Aging Versus Postmenopausal Osteoporosis: Bone Composition and Maturation Kinetics at Actively-Forming Trabecular Surfaces of Female Subjects Aged 1 to 84 Years. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2016, Volume: 31, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Bone Density; Child; Child, Preschool; Female; Humans; Ilium; Infant; Middle Aged; Models, Biological; Osteoporosis, Postmenopausal	2016
Mature enzymatic collagen cross-links, hydroxylysylpyridinoline and lysylpyridinoline, in the aging human vitreous. Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Child; Child, Preschool; Chromatography, High Pressure Liquid; Collagen; Female; Humans; Male; Middle Aged; Organ Size; Vitreous Body	2009
Mechanical properties and collagen cross-linking of the patellar tendon in old and young men. Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:3 Topics: Adult; Aged; Aging; Amino Acids; Arginine; Arm; Biomechanical Phenomena; Biopsy; Collagen; Glycation End Products, Advanced; Humans; Hydroxyproline; Knee; Lysine; Male; Movement; Muscle, Skeletal; Patellar Ligament; Protein-Lysine 6-Oxidase	2009
Computed tomography detects changes in contrast agent diffusion after collagen cross-linking typical to natural aging of articular cartilage. Osteoarthritis and cartilage, 2011, Volume: 19, Issue:10 Topics: Aging; Amino Acids; Animals; Arginine; Cartilage, Articular; Case-Control Studies; Cattle; Collagen; Contrast Media; Hindlimb; Ioxaglic Acid; Lysine; Patella; Tetroses; Tomography, X-Ray Computed	2011
Vitamin d status and indices of bone turnover in older European adults. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2011, Volume: 81, Issue:5 Topics: Aged; Aging; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Remodeling; Cross-Sectional Studies; Europe; Female; Humans; Male; Middle Aged; Osteocalcin; Vitamin D; Vitamin D Deficiency	2011
[Effect of normobaric hyperoxia on the markers of bone tissue metabolism]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2011, Volume: 57, Issue:6 Topics: Aging; Amino Acids; Animals; Biomarkers; Bone and Bones; Bone Development; Hyperoxia; Male; Peptide Fragments; Procollagen; Rats; Rats, Wistar	2011
Maternal dietary lipids alter bone chemical composition, mechanical properties, and histological characteristics of progeny of Japanese quail. Poultry science, 2003, Volume: 82, Issue:3 Topics: Adipose Tissue; Aging; Amino Acids; Animals; Biomechanical Phenomena; Body Weight; Bone and Bones; Chickens; Collagen; Coturnix; Dietary Fats; Female; Fish Oils; Oviposition; Soybean Oil; Tibia	2003
Age-related changes in collagen, pyridinoline, and deoxypyridinoline in normal human thoracic intervertebral discs. The journals of gerontology. Series A, Biological sciences and medical sciences, 2003, Volume: 58, Issue:5 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Amino Acids; Child; Child, Preschool; Collagen; Female; Humans; Infant; Intervertebral Disc; Male; Middle Aged; Sex Factors; Thoracic Vertebrae	2003
Tensile mechanical properties of bovine articular cartilage: variations with growth and relationships to collagen network components. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2003, Volume: 21, Issue:5 Topics: Aging; Amino Acids; Animals; Cartilage, Articular; Cattle; Collagen; Embryo, Mammalian; Femur; Tensile Strength	2003
Bone loss induced by dietary magnesium reduction to 10% of the nutrient requirement in rats is associated with increased release of substance P and tumor necrosis factor-alpha. The Journal of nutrition, 2004, Volume: 134, Issue:1 Topics: Aging; Alkaline Phosphatase; Amino Acids; Animals; Body Weight; Bone and Bones; Bone Density; Bone Diseases; Bone Remodeling; Calcitriol; Calcium; Diet; Immunohistochemistry; Macrophages; Magnesium; Magnesium Deficiency; Megakaryocytes; Nutritional Requirements; Osteocalcin; Osteoclasts; Parathyroid Hormone; Rats; Rats, Sprague-Dawley; Substance P; Tumor Necrosis Factor-alpha	2004
Elevation in urinary levels of pyridinium cross-links of collagen following chymopapain-induced degradation of articular cartilage in the rabbit knee provides evidence of metabolic changes in bone. Osteoarthritis and cartilage, 1993, Volume: 1, Issue:3 Topics: Aging; Amino Acids; Animals; Arthritis, Experimental; Cartilage, Articular; Chymopapain; Collagen; Dose-Response Relationship, Drug; Male; Rabbits	1993
Multigenerational exposure to genistein does not increase bone mineral density in rats. Bone, 2005, Volume: 37, Issue:5 Topics: Aging; Alkaline Phosphatase; Amino Acids; Animals; Body Weight; Bone Density; Bone Development; Dose-Response Relationship, Drug; Female; Femur; Genistein; Growth Inhibitors; Male; Rats; Rats, Sprague-Dawley	2005
Collagen, cross-linking, and advanced glycation end products in aging human skeletal muscle. Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 103, Issue:6 Topics: Actins; Activities of Daily Living; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Collagen; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Muscle Contraction; Muscle Strength; Muscular Diseases; Myofibrils; Myosins; Quadriceps Muscle	2007
[Age-related changes of the connective tissue]. Nihon rinsho. Japanese journal of clinical medicine, 1984, Volume: 42, Issue:5 Topics: Adolescent; Adult; Aged; Aging; Amino Acids; Animals; Aorta; Child; Child, Preschool; Collagen; Connective Tissue; Dipeptides; Humans; Infant; Infant, Newborn; Middle Aged; Rats	1984
Analysis of pyridinoline, a cross-linking compound of collagen fibers, in human urine. Journal of biochemistry, 1983, Volume: 94, Issue:4 Topics: Adolescent; Aging; Amino Acids; Child; Chromatography, High Pressure Liquid; Collagen; Creatinine; Cross-Linking Reagents; Humans	1983
Aging and cross-linking in human aorta. Biochemical and biophysical research communications, 1982, Dec-31, Volume: 109, Issue:4 Topics: Aged; Aging; Amino Acids; Aorta; Chromatography, High Pressure Liquid; Desmosine; Dipeptides; Humans; Isodesmosine; Peptide Fragments; Peptide Hydrolases; Proteins	1982
Age-related changes in pyridinoline content of rabbit collagen. Experimental gerontology, 1982, Volume: 17, Issue:1 Topics: Aging; Amino Acids; Animals; Collagen; Muscle Development; Muscles; Myocardium; Rabbits	1982
Changes in pyridinoline content of elastin during ontogeny. Mechanisms of ageing and development, 1981, Volume: 17, Issue:4 Topics: Aging; Amino Acids; Animals; Cattle; Chromatography, Gel; Elastin; Ligaments; Muscle, Smooth, Vascular; Rats; Spectrometry, Fluorescence	1981
Synthesis of pyridinoline during in vitro aging of bone collagen. Journal of biochemistry, 1981, Volume: 90, Issue:6 Topics: Aging; Amino Acids; Animals; Bone and Bones; Chickens; Collagen; In Vitro Techniques	1981
In vitro aging of pyridinoline crosslinks in bone and tendon collagens. Nihon geka hokan. Archiv fur japanische Chirurgie, 1981, Nov-01, Volume: 50, Issue:6 Topics: Aging; Amino Acids; Animals; Bone and Bones; Cattle; Collagen; In Vitro Techniques; Rabbits; Tendons	1981
Lysyl oxidase and Maillard reaction-mediated crosslinks in aging and osteoarthritic rabbit cartilage. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1995, Volume: 13, Issue:1 Topics: Aging; Amino Acids; Animals; Arginine; Cartilage, Articular; Collagen; Female; Lysine; Maillard Reaction; Osteoarthritis; Peptide Mapping; Protein-Lysine 6-Oxidase; Rabbits; Solubility	1995
Passive length-force properties of senescent diaphragm: relationship with collagen characteristics. Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:6 Topics: Aging; Amino Acids; Animals; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Diaphragm; Electric Stimulation; Hydroxyproline; In Vitro Techniques; Male; Muscle Contraction; Muscle Development; Rats; Rats, Inbred F344	1994
Age-related changes in the pyridinoline content of guinea pigs cartilage and Achilles tendon collagen. Journal of nutritional science and vitaminology, 1994, Volume: 40, Issue:2 Topics: Achilles Tendon; Adrenal Glands; Aging; Amino Acids; Animals; Ascorbic Acid; Cartilage; Collagen; Guinea Pigs; Heart; Liver; Lung; Male; Myocardium; Organ Size	1994
Urinary excretion level of hydroxylysylpyridinoline as an index of bone resorption. Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Bone Resorption; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Female; Humans; Male; Mass Spectrometry; Middle Aged; Osteoporosis; Reference Standards; Sex Factors	1994
Evaluation of an immunoassay method for the determination of urinary collagen crosslink excretion. Annals of clinical biochemistry, 1994, Volume: 31 ( Pt 4) Topics: Adult; Aged; Aging; Amino Acids; Antibody Specificity; Biomarkers; Bone Diseases, Metabolic; Bone Resorption; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Enzyme-Linked Immunosorbent Assay; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Osteoclasts; Osteoporosis; Reference Values; Reproducibility of Results	1994
Urinary excretion of hydroxy-pyridinium cross-links of collagen reflects skeletal growth velocity in normal children. Experimental and clinical endocrinology, 1994, Volume: 102, Issue:2 Topics: Adolescent; Adult; Aging; Amino Acids; Bone Development; Child; Child, Preschool; Creatinine; Female; Humans; Hydroxyproline; Male; Reference Values; Regression Analysis	1994
Quantitative analysis of crosslinks pyridinoline and pentosidine in articular cartilage of patients with bone and joint disorders. Arthritis and rheumatism, 1994, Volume: 37, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Arthritis, Rheumatoid; Bone Diseases; Cartilage, Articular; Chromatography, High Pressure Liquid; Chronic Kidney Disease-Mineral and Bone Disorder; Cross-Linking Reagents; Female; Femur Head Necrosis; Hip Joint; Humans; Joint Diseases; Knee Joint; Lysine; Male; Middle Aged; Osteoarthritis; Osteoporosis	1994
Age-related changes of urinary pyridinoline and deoxypyridinoline in Japanese subjects. Clinical and investigative medicine. Medecine clinique et experimentale, 1993, Volume: 16, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Humans; Infant; Japan; Male; Middle Aged; Reference Values	1993
Influence of ovariectomy on bone metabolism in very old rats. Calcified tissue international, 1996, Volume: 58, Issue:4 Topics: Aging; Alkaline Phosphatase; Amino Acids; Animals; Body Weight; Bone and Bones; Bone Density; Calcium; Estradiol; Female; Organ Size; Osteocalcin; Ovariectomy; Parathyroid Hormone; Progesterone; Rats	1996
Bone turnover markers and bone density across the menopausal transition. The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:9 Topics: Aging; Amino Acids; Biomarkers; Bone Density; Bone Remodeling; Bone Resorption; Collagen; Collagen Type I; Estradiol; Estrogen Replacement Therapy; Female; Femur; Follicle Stimulating Hormone; Humans; Inhibins; Luteinizing Hormone; Menopause; Middle Aged; Peptides; Postmenopause; Premenopause; Pyridinium Compounds; Spine	1996
Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1996, Volume: 11, Issue:3 Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Aging; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone Density; Bone Development; Bone Resorption; Cohort Studies; Cross-Sectional Studies; Disease Models, Animal; Female; Femur; Follicle Stimulating Hormone; Humans; Hydroxycholecalciferols; Lumbar Vertebrae; Osteocalcin; Osteoporosis, Postmenopausal; Parathyroid Hormone; Peptide Fragments; Premenopause; Procollagen; Radius	1996
The role of glycation cross-links in diabetic vascular stiffening. Diabetologia, 1996, Volume: 39, Issue:8 Topics: Adult; Aged; Aging; Amino Acids; Aorta, Thoracic; Arginine; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Elastin; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Time Factors	1996
Blotchy mice: a model of osteoarthritis associated with a metabolic defect. Osteoarthritis and cartilage, 1996, Volume: 4, Issue:3 Topics: Aging; Amino Acids; Animals; Aortic Rupture; Cartilage, Articular; Collagen; Collagen Diseases; Disease Models, Animal; Disease Progression; Elastin; Enzyme-Linked Immunosorbent Assay; Female; Femur; Male; Mice; Mice, Inbred C57BL; Osteoarthritis; Protein-Lysine 6-Oxidase; Stifle; Tibia	1996
Pyridinium crosslinks of collagen as a marker of bone resorption rates in children and adolescents: normal values and clinical application. Bone, 1996, Volume: 19, Issue:6 Topics: Adolescent; Aging; Amino Acids; Biomarkers; Bone Resorption; Child; Child, Preschool; Collagen; Female; Human Growth Hormone; Humans; Male; Poland; Pyridinium Compounds; Reference Values; Reproducibility of Results; Statistics, Nonparametric	1996
Effect of maturation and aging on the histomorphometric and biochemical characteristics of equine superficial digital flexor tendon. American journal of veterinary research, 1997, Volume: 58, Issue:4 Topics: Aging; Amino Acids; Animals; Blood Vessels; Collagen; Female; Horses; Male; Tendons; Ultrasonography	1997
Age-related alteration of cross-linking amino acids of elastin in human aorta. The Tohoku journal of experimental medicine, 1996, Volume: 180, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Aorta, Thoracic; Autopsy; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Desmosine; Elasticity; Elastin; Humans; Infant; Infant, Newborn; Isodesmosine; Middle Aged; Muscle Development; Muscle, Smooth, Vascular; Piperidines; Pyridines	1996
Changes in biomechanical properties, composition of collagen and elastin, and advanced glycation endproducts of the rat aorta in relation to age. Atherosclerosis, 1996, Dec-20, Volume: 127, Issue:2 Topics: Aging; Amino Acids; Animals; Aorta, Thoracic; Biomarkers; Biomechanical Phenomena; Blood Pressure; Calcium; Chromatography, High Pressure Liquid; Collagen; Elasticity; Elastin; Glycation End Products, Advanced; Hydroxyproline; Male; Rats; Rats, Wistar	1996
Bone mineral density changes during lactation: maternal, dietary, and biochemical correlates. The American journal of clinical nutrition, 1997, Volume: 65, Issue:6 Topics: Absorptiometry, Photon; Aging; Amino Acids; Analysis of Variance; Bone and Bones; Bone Density; Calcium; Diet; Diet Records; Estradiol; Female; Homeostasis; Humans; Lactation; Longitudinal Studies; Magnesium; Phosphates; Postprandial Period; Prolactin; Weaning	1997
Single-column high-performance liquid chromatographic-fluorescence detection of immature, mature, and senescent cross-links of collagen. Analytical biochemistry, 1997, Nov-01, Volume: 253, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Cartilage, Articular; Child; Child, Preschool; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Diaphyses; Dipeptides; Femur; Histidine; Humans; Indicators and Reagents; Infant; Lysine; Male; Middle Aged; Sensitivity and Specificity; Skin; Spectrometry, Fluorescence	1997
High-turnover osteopenia in preterm infants: determination of urinary pyridinium cross-links of collagen. Metabolism: clinical and experimental, 1998, Volume: 47, Issue:3 Topics: Aging; Amino Acids; Bone Density; Bone Diseases, Metabolic; Bone Remodeling; Collagen; Collagen Type I; Creatinine; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Male; Peptides	1998
Increased bone resorbing activity of peripheral monocyte culture supernatants in elderly women. The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:5 Topics: Adult; Aged; Aging; Amino Acids; Animals; Bone and Bones; Bone Density; Bone Resorption; Cells, Cultured; Culture Media, Conditioned; Cytokines; Female; Humans; Interleukin-1; Interleukin-6; Middle Aged; Monocytes; Postmenopause; Pregnancy; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha	1998
The effect of L-ascorbic acid on age-related changes of pyridinoline in cartilage collagen of guinea pigs. Journal of nutritional science and vitaminology, 1998, Volume: 44, Issue:2 Topics: Adrenal Glands; Aging; Amino Acids; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Cartilage; Collagen; Guinea Pigs; Liver; Male; Weight Gain	1998
Collagen crosslinks in human lumbar intervertebral disc aging. Spine, 1998, Aug-01, Volume: 23, Issue:15 Topics: Adult; Aged; Aging; Amino Acids; Arginine; Cadaver; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Lysine; Middle Aged	1998
Inhibition of cross-links in collagen is associated with reduced stiffness of the aorta in young rats. Atherosclerosis, 1998, Volume: 140, Issue:1 Topics: Aging; Amino Acids; Animals; Aorta; Collagen; Desmosine; Elasticity; Elastin; Female; Rats; Rats, Wistar; Structure-Activity Relationship	1998
Urinary markers of bone turnover in healthy children and adolescents: age-related changes and effect of puberty. Calcified tissue international, 1998, Volume: 63, Issue:5 Topics: Adolescent; Adult; Age Factors; Aging; Amino Acids; Biomarkers; Body Height; Body Weight; Bone Development; Child; Child, Preschool; Collagen; Collagen Type I; Creatinine; Female; Humans; Male; Middle Aged; Peptides; Puberty; Reference Values; Sex Characteristics	1998
Diurnal variation and age differences in the biochemical markers of bone turnover in horses. Journal of animal science, 1999, Volume: 77, Issue:1 Topics: Aging; Amino Acids; Animals; Biomarkers; Bone Remodeling; Circadian Rhythm; Horses; Hydrocortisone; Male; Osteocalcin	1999
Lysylhydroxylation and non-reducible crosslinking of human supraspinatus tendon collagen: changes with age and in chronic rotator cuff tendinitis. Annals of the rheumatic diseases, 1999, Volume: 58, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Child; Chronic Disease; Collagen; Cross-Linking Reagents; Humans; Hydroxylation; Hydroxylysine; Lysine; Middle Aged; Rotator Cuff; Tendinopathy	1999
Collagen crosslinks in human lumbar intervertebral disc aging. Spine, 1999, Jun-15, Volume: 24, Issue:12 Topics: Aging; Amino Acids; Collagen; Humans; Intervertebral Disc; Lumbar Vertebrae	1999
The role of collagen in the declining mechanical properties of aging human cortical bone. Journal of biomedical materials research, 1999, Volume: 45, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Biomechanical Phenomena; Bone and Bones; Bone Development; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Hot Temperature; Humans; Male; Middle Aged; Regression Analysis	1999
Age-related changes to the molecular and cellular components of equine flexor tendons. Equine veterinary journal, 1999, Volume: 31, Issue:5 Topics: Aging; Amino Acids; Animals; Collagen; DNA; Extracellular Matrix; Glycosaminoglycans; Horses; Microscopy, Electron; Myofibrils; Rupture; Tendon Injuries; Tendons; Water	1999
Effects of age, menopause and osteoporosis on free, peptide-bound and total pyridinium crosslink excretion. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1999, Volume: 9, Issue:5 Topics: Adult; Aged; Aging; Amino Acids; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Collagen; Collagen Type I; Enzyme-Linked Immunosorbent Assay; Evaluation Studies as Topic; Female; Humans; Immunoassay; Luminescent Measurements; Menopause; Middle Aged; Osteoporosis, Postmenopausal; Peptides; Pyridinium Compounds	1999
Racemization and isomerization of type I collagen C-telopeptides in human bone and soft tissues: assessment of tissue turnover. The Biochemical journal, 2000, Feb-01, Volume: 345 Pt 3 Topics: Aged; Aged, 80 and over; Aging; Amino Acids; Bone and Bones; Collagen; Connective Tissue; Cross-Linking Reagents; Female; Humans; Isomerism; Kinetics; Male; Middle Aged; Peptide Fragments	2000
Influence of different exercise levels and age on the biochemical characteristics of immature equine articular cartilage. Equine veterinary journal. Supplement, 1999, Issue:31 Topics: Aging; Amino Acids; Animals; Animals, Newborn; Cartilage, Articular; Collagen; DNA; Female; Glycosaminoglycans; Horses; Hydroxylysine; Male; Physical Conditioning, Animal; Random Allocation	1999
Exercise training attenuates aging-associated increases in collagen and collagen crosslinking of the left but not the right ventricle in the rat. European journal of applied physiology, 2001, Volume: 85, Issue:1-2 Topics: Aging; Amino Acids; Animals; Collagen; Cross-Linking Reagents; Extracellular Matrix; Heart Septum; Heart Ventricles; Male; Myocardium; Organ Size; Physical Conditioning, Animal; Rats; Rats, Inbred F344	2001
[Levels of mature cross-links and advanced glycation end product cross-links in human vitreous]. Nippon Ganka Gakkai zasshi, 2002, Volume: 106, Issue:1 Topics: Adult; Aged; Aging; Amino Acids; Arginine; Cross-Linking Reagents; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Vitreous Body	2002
Urinary collagen cross-links as biochemical markers of growth: an evaluation of biological variables. Annals of nutrition & metabolism, 2002, Volume: 46, Issue:2 Topics: Aging; Amino Acids; Anthropometry; Biomarkers; Body Height; Bone Development; Child, Preschool; Circadian Rhythm; Collagen; Cross-Linking Reagents; Female; Growth; Humans; Longitudinal Studies; Male; Pilot Projects; Predictive Value of Tests; Pyridinium Compounds	2002
Effect of vitamin D on the content of the stable crosslink, pyridinoline, in chick bone collagen. Biochemical and biophysical research communications, 1979, Nov-14, Volume: 91, Issue:1 Topics: Aging; Amino Acids; Animals; Bone and Bones; Bone Development; Chickens; Cholecalciferol; Collagen; Cross-Linking Reagents; Male; Pyridinium Compounds; Vitamin D Deficiency	1979
Aging- and training-induced alterations in collagen characteristics of rat left ventricle and papillary muscle. The American journal of physiology, 1992, Volume: 263, Issue:3 Pt 2 Topics: Aging; Amino Acids; Animals; Collagen; Female; Heart Ventricles; Myocardium; Papillary Muscles; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Reference Values	1992
Age-related changes in the concentration of hydroxypyridinium crosslinks in functionally different skeletal muscles. Matrix (Stuttgart, Germany), 1992, Volume: 12, Issue:4 Topics: Aging; Amino Acids; Animals; Chromatography, High Pressure Liquid; Hydroxyproline; Male; Muscles; Rats; Tendons	1992
Quantitation of urinary hydroxypyridinium cross-links from collagen by high-performance liquid chromatography. Scandinavian journal of clinical and laboratory investigation, 1992, Volume: 52, Issue:7 Topics: Aging; Amino Acids; Bone and Bones; Chromatography, High Pressure Liquid; Collagen; Creatinine; Female; Humans; Male; Menopause; Reference Values; Sex Characteristics	1992
Fluorophores from aging human articular cartilage. Journal of biochemistry, 1991, Volume: 110, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Cartilage, Articular; Chemical Fractionation; Child; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Female; Humans; Lysine; Male; Microbial Collagenase; Middle Aged; Solubility; Spectrometry, Fluorescence	1991
[Age changes in the level of pyridinoline cross-linking and ratio of soluble and insoluble collagen in human rib collagen]. Biokhimiia (Moscow, Russia), 1991, Volume: 56, Issue:9 Topics: Adult; Aging; Amino Acids; Cartilage; Cross-Linking Reagents; Humans; Infant; Middle Aged; Ribs; Solubility	1991
Changes with age in the urinary excretion of lysyl- and hydroxylysylpyridinoline, two new markers of bone collagen turnover. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1990, Volume: 5, Issue:7 Topics: Adult; Aged; Aging; Amino Acids; Biomarkers; Bone and Bones; Bone Resorption; Chromatography, High Pressure Liquid; Collagen; Female; Humans; Hydrolysis; Hydroxylysine; Lysine; Male; Middle Aged; Pyridinium Compounds; Reference Standards; Reference Values	1990
Isolation, purification and partial characterization of novel fluorophores from aging human insoluble collagen-rich tissue. Connective tissue research, 1989, Volume: 19, Issue:1 Topics: Aging; Amino Acids; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Paper; Collagen; Connective Tissue; Diabetes Mellitus; Dura Mater; Fluorescent Dyes; Humans; Hydroxyproline; Molecular Weight; Solubility; Spectrometry, Fluorescence; Spectrophotometry; Trypsin	1989
Response of immature chicken meniscus to strenuous exercise: biochemical studies of proteoglycan and collagen. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1988, Volume: 6, Issue:2 Topics: Adaptation, Physiological; Aging; Amino Acids; Animals; Chickens; Chondroitin Sulfates; Chromatography, Gel; Collagen; Dermatan Sulfate; Freeze Drying; Hexuronic Acids; Hyaluronic Acid; Male; Menisci, Tibial; Models, Biological; Physical Exertion; Proteoglycans; Random Allocation; Running	1988
Age-related changes in the content of non-reducible crosslinks in rat mandibular bone. Archives of oral biology, 1985, Volume: 30, Issue:5 Topics: Aging; Amino Acids; Animals; Collagen; Dipeptides; Male; Mandible; Rats	1985