pyridinolcarbamate has been researched along with Arteriosclerosis in 47 studies
Pyridinolcarbamate: A drug that has been given by mouth in the treatment of atherosclerosis and other vascular disorders, hyperlipidemias, and thrombo-embolic disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1408)
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The patient received since four years pyridinolcarbamate (Prodectin) because of obliterating peripheral arteriosclerosis." | 3.67 | [Pyridimocarbamate (prodectin)-induced acute liver damage, cirrhosis and primary liver cancer--accidental finding?]. ( Kendrey, G; Kiss, F; László, B, 1989) |
| " Long-term administration of antiatherosclerotic drugs Pyridinolcarbamate and Phtalazinole II normalized metabolic disorder in the aortic wall and reduced endothelaemia to normal values." | 1.27 | Metabolic changes in the arterial wall and endothelial injury in experimental methioninaemia. ( Hladovec, J; Mrhová, O; Urbanová, D, 1988) |
| "2." | 1.26 | Study of drugs affecting cholesterol-induced atherosclerosis in rabbits. ( Kim, DN; Kwak, YS; Lee, KT, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (97.87) | 18.7374 |
| 1990's | 1 (2.13) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Numano, F | 3 |
| Lee, WM | 2 |
| Lee, KT | 4 |
| Mrhová, O | 2 |
| Urbanová, D | 2 |
| Kim, DN | 2 |
| Schmee, J | 1 |
| Thomas, WA | 2 |
| Orbetzova, V | 1 |
| Jurukova, Z | 1 |
| Orbetzova, M | 1 |
| Bouissou, H | 5 |
| de Graeve, J | 2 |
| Julian, M | 5 |
| Pieraggi, MT | 5 |
| Thiers, JC | 2 |
| Kamburg, RA | 1 |
| Ibragimov, OB | 1 |
| Kondrat'eva, MB | 1 |
| Valeeva, IKh | 1 |
| Shamsutdinov, NSh | 1 |
| Belousov, IuB | 1 |
| Savenkov, PM | 1 |
| Sidel'man, AA | 1 |
| Parfenov, AS | 1 |
| Savenkov, MP | 1 |
| Shimamoto, T | 6 |
| Hidaka, H | 1 |
| Moriya, K | 2 |
| Kobayashi, M | 2 |
| Takahashi, T | 2 |
| Kukes, VG | 1 |
| Mashkovskiĭ, MD | 1 |
| Paskhina, TS | 1 |
| Borisov, VG | 1 |
| Shvarts, GIa | 1 |
| Eguchi, Y | 1 |
| Ishikawa, M | 2 |
| Mishima, Y | 1 |
| Kamiya, K | 1 |
| Sakaguchi, S | 1 |
| Kusaba, A | 1 |
| Sakuma, A | 1 |
| Szondy, E | 2 |
| Horváth, M | 2 |
| Füst, G | 2 |
| Fehér, J | 2 |
| Link, E | 2 |
| Gerö, S | 2 |
| Spesivtseva, VG | 1 |
| Mamaeva, GG | 1 |
| Starosel'tseva, LK | 1 |
| Tulemisov, EU | 1 |
| Bokaneva, IA | 1 |
| Albert, EN | 1 |
| Kassira, WN | 1 |
| Muesing, R | 1 |
| Vahouny, GV | 1 |
| Redisch, W | 3 |
| Clauss, RH | 2 |
| Rouen, LR | 3 |
| Katz, MC | 2 |
| Terry, EN | 3 |
| Kobayashi, DV | 1 |
| Klimov, AN | 2 |
| Ryzhenkov, VE | 2 |
| Petrova, LA | 1 |
| Polyakova, ED | 1 |
| Tararak, EM | 1 |
| Khechinashvili, GG | 1 |
| Mosina, IV | 1 |
| Gilli, J | 3 |
| Horsch, AK | 3 |
| Leyendecker, I | 1 |
| Schreiter, U | 3 |
| Bédi, J | 1 |
| Kosztovics, A | 1 |
| Pálos, LA | 1 |
| Clasuss, RH | 1 |
| Pola, P | 2 |
| Kuz'ko, NV | 1 |
| Valiensi, M | 1 |
| Riboli, E | 1 |
| Lombardi, M | 1 |
| Kwak, YS | 1 |
| Ito, S | 1 |
| Kendrey, G | 1 |
| Kiss, F | 1 |
| László, B | 1 |
| Hladovec, J | 1 |
| Toscano, S | 1 |
| Zelikovsky, A | 1 |
| Urca, I | 1 |
| Shaklai, M | 1 |
| de Vries, A | 1 |
| Ianushkevichus, Z | 1 |
| Bluzhas, I | 1 |
| Misiunene, N | 1 |
| Markunene, A | 1 |
| Gribauskas, P | 1 |
4 reviews available for pyridinolcarbamate and Arteriosclerosis
| Article | Year |
|---|---|
Chemotherapy of atherosclerosis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Triphosphate; Animals; Aorta; Arteriosclerosis; Citri | 1980 |
Drugs and foods on contraction of endothelial cells as a key mechanism in atherogenesis and treatment of atherosclerosis with endothelial-cell relaxants (cyclic AMP phosphodiesterase inhibitors).
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta; Arteries; Arteriosclerosis; Biological Transpor | 1975 |
New concept on atherogenesis.
Topics: Animals; Arteriosclerosis; Blood Proteins; Cholesterol; Cholesterol, Dietary; Endothelium; Fibrinoge | 1973 |
New concept on atherogenesis and treatment of atherosclerotic diseases.
Topics: Adenosine Diphosphate; Animals; Aorta; Arteriosclerosis; Blood Platelets; Blood Proteins; Blood Vess | 1972 |
6 trials available for pyridinolcarbamate and Arteriosclerosis
| Article | Year |
|---|---|
[Pharmacotherapy of peripheral arteriosclerosis].
Topics: Aged; Arteriosclerosis; Arteriosclerosis Obliterans; Azepines; Clinical Trials as Topic; Drug Evalua | 1978 |
A multiclinic double-blind trial of pyridinolcarbamate and inositol niacinate in ischemic ulcer due to chronic arterial occlusion.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Arterial Occlusive Diseases; Arteriosclerosis; Aspart | 1977 |
Progression of occlusive atherosclerosis. Long-term administration of pyridinol carbamate.
Topics: Age Factors; Aged; Arteriosclerosis; Carbamates; Clinical Trials as Topic; Digestive System; Drug Ev | 1975 |
[The importance of pyridinolcarbamate and clofibrate association in the treatment of arteriosclerosis].
Topics: Adult; Aged; Arteriosclerosis; Carbamates; Clinical Trials as Topic; Clofibrate; Drug Evaluation; Dr | 1975 |
[The importance of pyridinolcarbamate and clofibrate association in the treatment of arteriosclerosis].
Topics: Adult; Aged; Arteriosclerosis; Carbamates; Clinical Trials as Topic; Clofibrate; Drug Evaluation; Dr | 1975 |
A clinical trial with pyridinolcarbamate in the treatment of patients with obstructive diseases of the peripheral arteries.
Topics: Aged; Arterial Occlusive Diseases; Arteriosclerosis; Carbamates; Female; Femoral Artery; Gait; Human | 1973 |
37 other studies available for pyridinolcarbamate and Arteriosclerosis
| Article | Year |
|---|---|
Lack of effect of phenformin, pyridinolcarbamate combined with a decalcifying agent, and an onion--garlic mixture on growth and necrosis of aortic atherosclerosis in ballooned swine.
Topics: Animals; Aorta, Abdominal; Arteriosclerosis; Carbamates; Cholesterol; Clodronic Acid; Diet, Atheroge | 1980 |
Possible effect of drugs on arterial wall metabolism in experimental atherosclerosis.
Topics: Animals; Arteries; Arteriosclerosis; Carbamates; Fluoresceins; L-Lactate Dehydrogenase; Malate Dehyd | 1982 |
Anti-proliferative effect of pyridinolcarbamate and of aspirin in the early stages of atherogenesis in swine.
Topics: Animals; Aorta, Abdominal; Arteriosclerosis; Aspirin; Carbamates; Cholesterol; Coronary Vessels; Die | 1983 |
Antiatherogenic effect of pyridinolcarbamate (prodectin). Experimental study.
Topics: Animals; Aorta; Arteriosclerosis; Carbamates; Cholesterol, Dietary; Lipids; Lipoproteins; Male; Pyri | 1980 |
[Effect of pyridinol carbamate on long-term lathyrism and experimental atheroma in the rat. Histological and biochemical study].
Topics: Aminopropionitrile; Animals; Arteriosclerosis; Carbamates; Cholesterol; Diet, Atherogenic; Lathyrism | 1980 |
Long term lathyrism and atherogenic diet in the rat. Protective action of pyridinol carbamate.
Topics: Aminopropionitrile; Animals; Aorta; Arteriosclerosis; Carbamates; Cholesterol; Diet, Atherogenic; La | 1980 |
[The comparative characteristics of the antiatherogenic effect of xymedon and parmidine].
Topics: Animals; Aorta; Arteriosclerosis; Cholesterol, Dietary; Disease Models, Animal; Drug Evaluation, Pre | 1993 |
Hyperreactive arterial endothelial cells: a clue for the treatment of atherosclerosis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta, Thoracic; Arteries; Arteriosclerosis; Carbon; C | 1976 |
[Mechanism of action and clinical effectiveness of the new Soviet-made drug parmidin in the treatment of arteriosclerosis and ischemic heart disease].
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aprotinin; Arginine; Arterioscler | 1978 |
Hyperreactive arterial endothelial cells in atherogenesis and cyclic AMP phosphodiesterase inhibitor in prevention and treatment of atherosclerotic disorders.
Topics: Actomyosin; Angiotensin II; Animals; Arteries; Arteriosclerosis; Bucladesine; Carbon; Chickens; Cycl | 1975 |
[Synthetic studies of antiatherogenic agents. (VI) Syntheses of carbamate derivative of substituted phthalazinones (author's transl)].
Topics: Arteriosclerosis; Carbamates; Chemical Phenomena; Chemistry; Ethylenediamines; Phthalazines; Pyridaz | 1977 |
Partial suppression by pyridinolcarbamate of growth and necrosis of atherosclerotic lesions in swine subjected to an atherogenic regimen that produces advanced lesions.
Topics: Animals; Aorta; Aorta, Abdominal; Arteriosclerosis; Calcinosis; Carbamates; Cholesterol; Cholesterol | 1979 |
[The effect of clofibrate (Miscleron) and pyridinol carbamate (Prodectin) on immunologic factors in experimental arteriosclerosis].
Topics: Animals; Antigen-Antibody Complex; Arteriosclerosis; Carbamates; Cell Migration Inhibition; Choleste | 1979 |
[Hydroxyproline indicators before and after treatment of diabetic angiopathies].
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Diabetic Angiopathies; Female; Humans; Hydroxyproline; Ma | 1978 |
The effect of clofibrate and pyridinol carbamate on the circulating immune complexes and cellular immune response in experimental atherosclerosis.
Topics: Animals; Antigen-Antibody Complex; Arteriosclerosis; Carbamates; Cell Migration Inhibition; Choleste | 1978 |
Pyridinolcarbamate and experimental atherosclerosis. Correlation of hypocholesterolemic and antiatherogenic effects.
Topics: Animals; Arteriosclerosis; Carbamates; Cholesterol; Cholesterol, Dietary; Male; Phospholipids; Pyrid | 1978 |
Hyperreactive arterial endothelial cells in atherogenesis. Effect of smooth muscle relaxants.
Topics: Actomyosin; Animals; Aorta; Arteriosclerosis; Biological Transport; Carbamates; Carbon; Colchicine; | 1977 |
Experimental investigation of hypolipidemic and anti-atherosclerotic drugs with different mechanism of action.
Topics: Animals; Arteriosclerosis; Carbamates; Cholesterol; Chondroitin; Chondroitin Sulfates; Cricetinae; G | 1977 |
[Effect of ethirazol and parmidine ofn the development of experimental atherosclerosis in rabbits].
Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Carbamates; Diet, Atherogenic; Male; Pyrazoles; | 1976 |
[Lipid synthesis in normal and atherosclerotic human intima in vitro under the effect of pyridinolcarbamate].
Topics: Adult; Aged; Arteriosclerosis; Carbamates; Femoral Artery; Humans; Lipids; Middle Aged; Pyridinolcar | 1976 |
Clinical and laboratory examinations with Prodectin.
Topics: Arteriosclerosis; Carbamates; Humans; Male; Middle Aged; Platelet Aggregation; Pyridinolcarbamate | 1976 |
[Role of physiologically active substances in the pathogenesis and therapy of atherosclerosis].
Topics: Animals; Arteriosclerosis; Carbamates; Chondroitin; Chondroitin Sulfates; Mevalonic Acid; Pyridinolc | 1976 |
Attempts to delay progression in occlusive atherosclerosis.
Topics: Arteriosclerosis; Blood Platelets; Carbamates; Female; Humans; Male; Middle Aged; Pyridinolcarbamate | 1976 |
Effect of pyridinolcarbamate (PDC) on surface microvessels in man: preliminary findings.
Topics: Arteriosclerosis; Capillary Permeability; Carbamates; Humans; Microcirculation; Pyridinolcarbamate | 1975 |
[Pyridinolcarbamate treatment of ischemic heart disease].
Topics: Aged; Arteriosclerosis; Carbamates; Coronary Disease; Humans; Intracranial Arteriosclerosis; Middle | 1976 |
[Therapeutic results with combination of pyridinolcarbamate and clofibrate in atherosclerotic patients].
Topics: Adult; Aged; Arteriosclerosis; Carbamates; Clofibrate; Coronary Disease; Drug Combinations; Female; | 1976 |
Study of drugs affecting cholesterol-induced atherosclerosis in rabbits.
Topics: Animals; Arteriosclerosis; Aspirin; Chloroquine; Cholesterol, Dietary; Clomipramine; Hydroxyurea; Ma | 1976 |
Preparation and evaluation of the antiatherosclerotic activity of unsymmetrical pyridinolcarbamates.
Topics: Animals; Arteriosclerosis; Molecular Structure; Phosphodiesterase Inhibitors; Phthalazines; Pyridino | 1989 |
[Pyridimocarbamate (prodectin)-induced acute liver damage, cirrhosis and primary liver cancer--accidental finding?].
Topics: Acute Disease; Arteriosclerosis; Carbamates; Chemical and Drug Induced Liver Injury; Female; Humans; | 1989 |
Metabolic changes in the arterial wall and endothelial injury in experimental methioninaemia.
Topics: Animals; Arteries; Arteriosclerosis; Endothelium, Vascular; Female; Homocysteine; Methionine; Phthal | 1988 |
[Proceedings: Effect of pyridinolcarbamate on the lipid metabolism of normal and atherosclerotic intima in human femoral arteries].
Topics: Arteriosclerosis; Carbamates; Femoral Artery; Humans; Hypolipidemic Agents; In Vitro Techniques; Lip | 1974 |
[Current trends in the therapy of arteriosclerotic disease].
Topics: Adult; Aged; Arteriosclerosis; Cholesterol; Chylomicrons; Clofibrate; Female; Humans; Hyperlipidemia | 1974 |
[Chronic lathyrism: inhibitory effect of pyridinol carbamate on aortic atheroma in the rat (author's transl)].
Topics: Aminopropionitrile; Animals; Aorta; Aortic Diseases; Arteriosclerosis; Chronic Disease; Diet, Athero | 1974 |
[Effect of pyridinolcarbamate on lipid metabolism of normal and arteriosclerotic intima in human femoral arteries].
Topics: Arteriosclerosis; Carbamates; Femoral Artery; Humans; In Vitro Techniques; Lipid Metabolism; Pyridin | 1974 |
Aortic lathyrism: ultrastructural study of lesions in the aortic wall and the protective effect of pyridinol carbamate.
Topics: Aging; Aminopropionitrile; Animals; Aorta; Arteriosclerosis; Carbamates; Dietary Fats; Histiocytes; | 1974 |
[Protective effect of carbamate pyridinol on experimental atheroma in the rat].
Topics: Aminopropionitrile; Animals; Arteriosclerosis; Carbamates; Diet, Atherogenic; Hypolipidemic Agents; | 1974 |
[Certain clinical and biochemical results of pyridinolcarbamate treatment of patients with ischemic heart disease].
Topics: Adult; Aged; Arteriosclerosis; Hemostasis; Humans; Hypolipidemic Agents; Male; Myocardial Infarction | 1973 |