Page last updated: 2024-10-20

pyridine and Protein Aggregation, Pathological

pyridine has been researched along with Protein Aggregation, Pathological in 1 studies

azine : An organonitrogen compound of general structure RCH=N-N=CHR or RR'C=N-N=CRR'.

Protein Aggregation, Pathological: A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.

Research Excerpts

ExcerptRelevanceReference
"Parkinson's disease is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra, as well as the accumulation of intraneuronal proteinaceous inclusions known as Lewy bodies and Lewy neurites."1.72The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains. ( Manglano-Artuñedo, Z; Outeiro, TF; Peña-Díaz, S; Pinheiro, F; Pujols, J; Santos, J; Vasili, E; Ventura, S, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Peña-Díaz, S1
Pujols, J1
Vasili, E1
Pinheiro, F1
Santos, J1
Manglano-Artuñedo, Z1
Outeiro, TF1
Ventura, S1

Other Studies

1 other study available for pyridine and Protein Aggregation, Pathological

ArticleYear
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:5

    Topics: alpha-Synuclein; Amyloid; Humans; Lewy Bodies; Neuroprotective Agents; Parkinson Disease; Polymeriza

2022