Page last updated: 2024-10-20

pyridine and Lewy Body Disease

pyridine has been researched along with Lewy Body Disease in 1 studies

azine : An organonitrogen compound of general structure RCH=N-N=CHR or RR'C=N-N=CRR'.

Lewy Body Disease: A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)

Research Excerpts

ExcerptRelevanceReference
"The aggregation of alpha-synuclein (alphaS) has been implicated as a critical step in the development of Lewy body diseases (LBD) and multiple system atrophy (MSA)."7.74Anti-fibrillogenic and fibril-destabilizing activity of nicotine in vitro: implications for the prevention and therapeutics of Lewy body diseases. ( Hirohata, M; Ono, K; Yamada, M, 2007)
"The aggregation of alpha-synuclein (alphaS) has been implicated as a critical step in the development of Lewy body diseases (LBD) and multiple system atrophy (MSA)."3.74Anti-fibrillogenic and fibril-destabilizing activity of nicotine in vitro: implications for the prevention and therapeutics of Lewy body diseases. ( Hirohata, M; Ono, K; Yamada, M, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ono, K1
Hirohata, M1
Yamada, M1

Other Studies

1 other study available for pyridine and Lewy Body Disease

ArticleYear
Anti-fibrillogenic and fibril-destabilizing activity of nicotine in vitro: implications for the prevention and therapeutics of Lewy body diseases.
    Experimental neurology, 2007, Volume: 205, Issue:2

    Topics: alpha-Synuclein; Benzothiazoles; Humans; Kinetics; Lewy Body Disease; Microfibrils; Microscopy, Atom

2007