pyrazolopyridine and Vomiting

pyrazolopyridine has been researched along with Vomiting* in 1 studies

Other Studies

1 other study(ies) available for pyrazolopyridine and Vomiting

Article	Year
New orally active PDE4 inhibitors with therapeutic potential. Bioorganic & medicinal chemistry letters, 2004, Jan-05, Volume: 14, Issue:1 Structural optimization of pyrazolopyridine derivative 2, which is one of the newly discovered chemical leads for PDE4 inhibitors from our in-house library, was carried out successfully. The process of discovery of new orally active PDE4 inhibitors, which are expected to possess therapeutic potential, is presented and their structure-activity relationships are discussed. Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Animals; Bronchoconstriction; Bronchoconstrictor Agents; Cyclic Nucleotide Phosphodiesterases, Type 4; Ferrets; Gastric Emptying; Guinea Pigs; Humans; Phosphodiesterase Inhibitors; Pyrazoles; Pyridines; Rats; Tumor Necrosis Factor-alpha; Vomiting	2004

Article

Year

New orally active PDE4 inhibitors with therapeutic potential.

Bioorganic & medicinal chemistry letters, 2004, Jan-05, Volume: 14, Issue:1

Structural optimization of pyrazolopyridine derivative 2, which is one of the newly discovered chemical leads for PDE4 inhibitors from our in-house library, was carried out successfully. The process of discovery of new orally active PDE4 inhibitors, which are expected to possess therapeutic potential, is presented and their structure-activity relationships are discussed.

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Animals; Bronchoconstriction; Bronchoconstrictor Agents; Cyclic Nucleotide Phosphodiesterases, Type 4; Ferrets; Gastric Emptying; Guinea Pigs; Humans; Phosphodiesterase Inhibitors; Pyrazoles; Pyridines; Rats; Tumor Necrosis Factor-alpha; Vomiting

2004