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pyrazole and Trypanosomiasis, African

pyrazole has been researched along with Trypanosomiasis, African in 2 studies

1H-pyrazole : The 1H-tautomer of pyrazole.

Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.

Research Excerpts

ExcerptRelevanceReference
"African sleeping sickness or human African trypanosomiasis, caused by Trypanosoma brucei spp."1.36N-myristoyltransferase inhibitors as new leads to treat sleeping sickness. ( Brand, S; Brannigan, JA; Brenk, R; Cleghorn, LA; Fairlamb, AH; Ferguson, MA; Frearson, JA; Gilbert, IH; Guther, ML; Hallyburton, I; Hodgkinson, M; Hui, R; McElroy, SP; Mpamhanga, CP; Price, HP; Qiu, W; Raimi, OG; Read, KD; Robinson, DA; Smid, O; Smith, DF; Stojanovski, L; Torrie, LS; van Aalten, DM; Wilkinson, AJ; Wyatt, PG, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Urich, R1
Grimaldi, R1
Luksch, T1
Frearson, JA2
Brenk, R2
Wyatt, PG2
Brand, S1
McElroy, SP1
Cleghorn, LA1
Smid, O1
Stojanovski, L1
Price, HP1
Guther, ML1
Torrie, LS1
Robinson, DA1
Hallyburton, I1
Mpamhanga, CP1
Brannigan, JA1
Wilkinson, AJ1
Hodgkinson, M1
Hui, R1
Qiu, W1
Raimi, OG1
van Aalten, DM1
Gilbert, IH1
Read, KD1
Fairlamb, AH1
Ferguson, MA1
Smith, DF1

Other Studies

2 other studies available for pyrazole and Trypanosomiasis, African

ArticleYear
The design and synthesis of potent and selective inhibitors of Trypanosoma brucei glycogen synthase kinase 3 for the treatment of human african trypanosomiasis.
    Journal of medicinal chemistry, 2014, Sep-25, Volume: 57, Issue:18

    Topics: Adenosine Triphosphate; Binding Sites; Chemistry Techniques, Synthetic; Cyclin-Dependent Kinase 2; D

2014
N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.
    Nature, 2010, Apr-01, Volume: 464, Issue:7289

    Topics: Acyltransferases; Aminopyridines; Animals; Antiparasitic Agents; Enzyme Assays; Enzyme Inhibitors; F

2010