pyrazole has been researched along with Purpura, Thrombocytopenic, Idiopathic in 1 studies
1H-pyrazole : The 1H-tautomer of pyrazole.
Purpura, Thrombocytopenic, Idiopathic: Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Idiopathic or immune thrombocytopenia (ITP) is a serious clinical disorder involving the destruction of platelets by macrophages." | 1.40 | Structure-activity relationships of pyrazole derivatives as potential therapeutics for immune thrombocytopenias. ( Bareau, MC; Bello, AM; Branch, DR; Chakka, SK; Katsman, Y; Kotra, LP; Neschadim, A; Purohit, MK; Salum, N; Scovell, I, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Purohit, MK | 1 |
| Chakka, SK | 1 |
| Scovell, I | 1 |
| Neschadim, A | 1 |
| Bello, AM | 1 |
| Salum, N | 1 |
| Katsman, Y | 1 |
| Bareau, MC | 1 |
| Branch, DR | 1 |
| Kotra, LP | 1 |
1 other study available for pyrazole and Purpura, Thrombocytopenic, Idiopathic
| Article | Year |
|---|---|
Structure-activity relationships of pyrazole derivatives as potential therapeutics for immune thrombocytopenias.
Topics: Antibodies; Erythrocytes; Humans; Leukocytes, Mononuclear; Phagocytosis; Purpura, Thrombocytopenic, | 2014 |