pyrazole has been researched along with Peritonitis in 1 studies
1H-pyrazole : The 1H-tautomer of pyrazole.
Peritonitis: INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Derived from an indole-containing high-throughput screen hit, optimization efforts resulted in potent and selective 6-substituted indoles with good oral bioavailability and in vivo activity." | 1.56 | Discovery of a novel indole pharmacophore for the irreversible inhibition of myeloperoxidase (MPO). ( Axford, L; Cohick, E; Dales, N; Deng, L; Hamann, LG; Harrison, TJ; Hollis-Symynkywicz, M; Kecman, S; Lee, L; Loi, S; Marcinkeviciene, J; Marro, ML; Papillon, JPN; Patnaik, A; Patterson, AW; Regard, JB; Ren, X, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patnaik, A | 1 |
| Axford, L | 1 |
| Deng, L | 1 |
| Cohick, E | 1 |
| Ren, X | 1 |
| Loi, S | 1 |
| Kecman, S | 1 |
| Hollis-Symynkywicz, M | 1 |
| Harrison, TJ | 1 |
| Papillon, JPN | 1 |
| Dales, N | 1 |
| Hamann, LG | 1 |
| Lee, L | 1 |
| Regard, JB | 1 |
| Marcinkeviciene, J | 1 |
| Marro, ML | 1 |
| Patterson, AW | 1 |
1 other study available for pyrazole and Peritonitis
| Article | Year |
|---|---|
Discovery of a novel indole pharmacophore for the irreversible inhibition of myeloperoxidase (MPO).
Topics: Animals; Enzyme Inhibitors; Half-Life; Indoles; Mice; Peritonitis; Peroxidase; Pyrazoles; Structure- | 2020 |