pyrazole has been researched along with Parkinson Disease in 2 studies
1H-pyrazole : The 1H-tautomer of pyrazole.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, X | 1 |
| Yu, Y | 1 |
| Tu, Z | 1 |
| Turriani, E | 1 |
| Lázaro, DF | 1 |
| Ryazanov, S | 1 |
| Leonov, A | 1 |
| Giese, A | 1 |
| Schön, M | 1 |
| Schön, MP | 1 |
| Griesinger, C | 1 |
| Outeiro, TF | 1 |
| Arndt-Jovin, DJ | 1 |
| Becker, D | 1 |
1 review available for pyrazole and Parkinson Disease
| Article | Year |
|---|---|
Pyrazole Scaffold Synthesis, Functionalization, and Applications in Alzheimer's Disease and Parkinson's Disease Treatment (2011-2020).
Topics: Alzheimer Disease; Animals; Humans; Molecular Structure; Parkinson Disease; Pyrazoles | 2021 |
1 other study available for pyrazole and Parkinson Disease
| Article | Year |
|---|---|
Treatment with diphenyl-pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death.
Topics: alpha-Synuclein; Animals; Autophagy; Benzodioxoles; Biphenyl Compounds; Cell Death; Cell Line, Tumor | 2017 |