Page last updated: 2024-10-20

pyrazole and Pain

pyrazole has been researched along with Pain in 6 studies

1H-pyrazole : The 1H-tautomer of pyrazole.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"A phenylbutazone-like pyrazole derivative, Sandoz KB-95, claimed to have antiserotonin, anti-inflammatory and analgesic properties, was tested on patients with rheumatoid arthritis."7.64Therapeutic trial of a pyrazole derivative, KB-95, for patients with rheumatoid arthritis. ( FORD, DK; PRICE, GE, 1963)
"A phenylbutazone-like pyrazole derivative, Sandoz KB-95, claimed to have antiserotonin, anti-inflammatory and analgesic properties, was tested on patients with rheumatoid arthritis."3.64Therapeutic trial of a pyrazole derivative, KB-95, for patients with rheumatoid arthritis. ( FORD, DK; PRICE, GE, 1963)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gulnaz, AR1
Mohammed, YHE1
Khanum, SA1
Abd El Razik, HA1
Badr, MH1
Atta, AH1
Mouneir, SM1
Abu-Serie, MM1
Batista, DC1
Silva, DPB1
Florentino, IF1
Cardoso, CS1
Gonçalves, MP1
Valadares, MC1
Lião, LM1
Sanz, G1
Vaz, BG1
Costa, EA1
Menegatti, R1
Singh, A1
Kaur, M1
Sharma, S1
Bhatti, R1
Singh, P1
Vijesh, AM1
Isloor, AM1
Shetty, P1
Sundershan, S1
Fun, HK1
PRICE, GE1
FORD, DK1

Other Studies

6 other studies available for pyrazole and Pain

ArticleYear
Design, synthesis and molecular docking of benzophenone conjugated with oxadiazole sulphur bridge pyrazole pharmacophores as anti inflammatory and analgesic agents.
    Bioorganic chemistry, 2019, Volume: 92

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Cyclooxyge

2019
Benzodioxole-Pyrazole Hybrids as Anti-Inflammatory and Analgesic Agents with COX-1,2/5-LOX Inhibition and Antioxidant Potential.
    Archiv der Pharmazie, 2017, Volume: 350, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arachidonate 5-Lipoxygen

2017
Anti-inflammatory effect of a new piperazine derivative: (4-methylpiperazin-1-yl)(1-phenyl-1H-pyrazol-4-yl)methanone.
    Inflammopharmacology, 2018, Volume: 26, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; BALB 3T3 Cells; Carrageenan; Cell Line; Cell Movement

2018
Rational design, synthesis and evaluation of chromone-indole and chromone-pyrazole based conjugates: identification of a lead for anti-inflammatory drug.
    European journal of medicinal chemistry, 2014, Apr-22, Volume: 77

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chromones; Cyclooxygenase 1; Cyclooxyge

2014
New pyrazole derivatives containing 1,2,4-triazoles and benzoxazoles as potent antimicrobial and analgesic agents.
    European journal of medicinal chemistry, 2013, Volume: 62

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Benzoxazoles; Dose-Response

2013
Therapeutic trial of a pyrazole derivative, KB-95, for patients with rheumatoid arthritis.
    Canadian Medical Association journal, 1963, May-11, Volume: 88

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; Double-Blind Method; Humans; M

1963