pyrazole has been researched along with Neoplasms in 15 studies
1H-pyrazole : The 1H-tautomer of pyrazole.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Excerpt | Relevance | Reference |
---|---|---|
"In 1956, the anti-cancer activity of pyrazolopyrimidine was evaluated for the first time with appreciable results." | 2.66 | An assessment study of known pyrazolopyrimidines: Chemical methodology and cellular activity. ( Chanda, K; Rao, RN, 2020) |
"Pyrazole nucleus is a unique structural scaffold which acts as an interesting template for combinatorial as well as medicinal chemistry." | 2.58 | The Synthetic and Biological Attributes of Pyrazole Derivatives: A Review. ( Dwivedi, J; Jain, S; Sharma, S; Singh, A, 2018) |
"Pyrazole has been the topic of interest for thousands of researchers across the world because of its wide spectrum pharmacological activities." | 2.49 | Pyrazole scaffold: a remarkable tool in the development of anticancer agents. ( Jain, N; Jain, S; Kumar, H; Saini, D, 2013) |
"The in vitro anticancer evaluation revealed that compounds 2a and 4-6(a) exhibited increased potency towards CNS SNB-75 and Renal UO-31 cancer cell lines." | 1.40 | Synthesis, in vitro anticancer evaluation and in silico studies of novel imidazo[2,1-b]thiazole derivatives bearing pyrazole moieties. ( Ali, AR; El-Bendary, ER; Ghaly, MA; Shehata, IA, 2014) |
"To examine the anticancer activity several novel thiazolone-based compounds containing 5-aryl-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl framework were obtained." | 1.35 | Synthesis of novel thiazolone-based compounds containing pyrazoline moiety and evaluation of their anticancer activity. ( Gzella, A; Havrylyuk, D; Lesyk, R; Vasylenko, O; Zaprutko, L; Zimenkovsky, B, 2009) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (13.33) | 29.6817 |
2010's | 11 (73.33) | 24.3611 |
2020's | 2 (13.33) | 2.80 |
Authors | Studies |
---|---|
Muravev, AA | 1 |
Voloshina, AD | 1 |
Sapunova, AS | 1 |
Gabdrakhmanova, FB | 1 |
Lenina, OA | 1 |
Petrov, KA | 1 |
Shityakov, S | 1 |
Skorb, EV | 1 |
Solovieva, SE | 1 |
Antipin, IS | 1 |
Rao, RN | 1 |
Chanda, K | 1 |
Dwivedi, J | 1 |
Sharma, S | 1 |
Jain, S | 2 |
Singh, A | 1 |
Wang, PF | 1 |
Wang, ZF | 1 |
Qiu, HY | 1 |
Huang, Y | 1 |
Hu, HM | 1 |
Wang, ZC | 1 |
Zhu, HL | 2 |
Koca, İ | 1 |
Özgür, A | 1 |
Coşkun, KA | 1 |
Tutar, Y | 1 |
Kumar, H | 1 |
Saini, D | 1 |
Jain, N | 1 |
Ali, AR | 1 |
El-Bendary, ER | 1 |
Ghaly, MA | 1 |
Shehata, IA | 1 |
Cankara Pirol, Ş | 1 |
Çalışkan, B | 1 |
Durmaz, I | 1 |
Atalay, R | 1 |
Banoglu, E | 1 |
Zhuang, C | 1 |
Sheng, C | 1 |
Shin, WS | 1 |
Wu, Y | 1 |
Li, J | 1 |
Yao, J | 1 |
Dong, G | 1 |
Zhang, W | 2 |
Sham, YY | 1 |
Miao, Z | 1 |
Havrylyuk, D | 1 |
Zimenkovsky, B | 1 |
Vasylenko, O | 1 |
Zaprutko, L | 1 |
Gzella, A | 1 |
Lesyk, R | 1 |
Mahindroo, N | 1 |
Connelly, MC | 1 |
Punchihewa, C | 1 |
Kimura, H | 1 |
Smeltzer, MP | 1 |
Wu, S | 1 |
Fujii, N | 1 |
Insuasty, B | 1 |
Tigreros, A | 1 |
Orozco, F | 1 |
Quiroga, J | 1 |
Abonía, R | 1 |
Nogueras, M | 1 |
Sanchez, A | 1 |
Cobo, J | 1 |
Lv, PC | 1 |
Li, HQ | 1 |
Sun, J | 1 |
Zhou, Y | 1 |
Bandgar, BP | 1 |
Totre, JV | 1 |
Gawande, SS | 1 |
Khobragade, CN | 1 |
Warangkar, SC | 1 |
Kadam, PD | 1 |
Sobiesiak, M | 1 |
Lorenz, IP | 1 |
Mayer, P | 1 |
Woźniczka, M | 1 |
Kufelnicki, A | 1 |
Krajewska, U | 1 |
Rozalski, M | 1 |
Budzisz, E | 1 |
3 reviews available for pyrazole and Neoplasms
Article | Year |
---|---|
An assessment study of known pyrazolopyrimidines: Chemical methodology and cellular activity.
Topics: Antineoplastic Agents; Cell Proliferation; Humans; Molecular Structure; Neoplasms; Phosphotransferas | 2020 |
The Synthetic and Biological Attributes of Pyrazole Derivatives: A Review.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Antineoplastic Agents; Antiox | 2018 |
Pyrazole scaffold: a remarkable tool in the development of anticancer agents.
Topics: Animals; Antineoplastic Agents; Humans; Models, Molecular; Neoplasms; Pyrazoles | 2013 |
12 other studies available for pyrazole and Neoplasms
Article | Year |
---|---|
Calix[4]arene-pyrazole conjugates as potential cancer therapeutics.
Topics: Animals; Calixarenes; HeLa Cells; Humans; Mice; Neoplasms; Porifera; Pyrazoles | 2023 |
Identification and Biological Evaluation of Novel Type II B-Raf
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Line, Tumor; Drug Design; Female; Humans | 2018 |
Synthesis and anticancer activity of acyl thioureas bearing pyrazole moiety.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Neoplasms; Pyrazoles; Structure | 2013 |
Synthesis, in vitro anticancer evaluation and in silico studies of novel imidazo[2,1-b]thiazole derivatives bearing pyrazole moieties.
Topics: Antineoplastic Agents; Cell Line, Tumor; Computer Simulation; Drug Design; Drug Screening Assays, An | 2014 |
Synthesis and preliminary mechanistic evaluation of 5-(p-tolyl)-1-(quinolin-2-yl)pyrazole-3-carboxylic acid amides with potent antiproliferative activity on human cancer cell lines.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carboxylic Acids; Cell Cycle Checkpoints; Cell | 2014 |
A novel drug discovery strategy: mechanistic investigation of an enantiomeric antitumor agent targeting dual p53 and NF-κB pathways.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Proliferation; Drug Discovery; Dr | 2014 |
Synthesis of novel thiazolone-based compounds containing pyrazoline moiety and evaluation of their anticancer activity.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Human | 2009 |
Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Genes, Rep | 2009 |
Synthesis of novel pyrazolic analogues of chalcones and their 3-aryl-4-(3-aryl-4,5-dihydro-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazole derivatives as potential antitumor agents.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chalcones; Drug Screening A | 2010 |
Synthesis and biological evaluation of pyrazole derivatives containing thiourea skeleton as anticancer agents.
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Computer Simulation; ErbB Receptors; Humans; | 2010 |
Synthesis of novel 3,5-diaryl pyrazole derivatives using combinatorial chemistry as inhibitors of tyrosinase as well as potent anticancer, anti-inflammatory agents.
Topics: Agaricales; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Cytokines; Drug Scree | 2010 |
Synthesis, X-ray structure and cytotoxic effect of nickel(II) complexes with pyrazole ligands.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chelating Agents; Coordination Complexes; Cr | 2011 |