Page last updated: 2024-10-20

pyrazole and Lung Neoplasms

pyrazole has been researched along with Lung Neoplasms in 6 studies

1H-pyrazole : The 1H-tautomer of pyrazole.

Lung Neoplasms: Tumors or cancer of the LUNG.

Research Excerpts

ExcerptRelevanceReference
"Lung cancer is the leading cause of cancer deaths worldwide and non-small cell lung carcinoma (NSCLC), a heterogeneous class of tumors, represents approximately 85% of all new lung cancer diagnosis."1.48Targeting apoptosis by 1,2-diazole through regulation of EGFR, Bcl-2 and CDK-2 mediated signaling pathway in human non-small cell lung carcinoma A549 cells. ( Elangovan, P; Niranjali Devaraj, S; Sakthivel, KM; Vinod Prabhu, V, 2018)
"Curcumin has shown promising therapeutic utilities for many diseases, including cancer; however, its clinical application is severely limited because of its poor stability under physiological conditions."1.39Stable and potent analogues derived from the modification of the dicarbonyl moiety of curcumin. ( Basu, G; Bhattacharyya, B; Chakrabarti, P; Chakraborti, G; Chakraborti, S; Das, A; Dhar, G; Dwivedi, V; Poddar, A; Surolia, A, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vinod Prabhu, V1
Elangovan, P1
Niranjali Devaraj, S1
Sakthivel, KM1
Chakraborti, S1
Dhar, G1
Dwivedi, V1
Das, A1
Poddar, A1
Chakraborti, G1
Basu, G1
Chakrabarti, P1
Surolia, A1
Bhattacharyya, B1
Marani, M1
Paone, A1
Fiascarelli, A1
Macone, A1
Gargano, M1
Rinaldo, S1
Giardina, G1
Pontecorvi, V1
Koes, D1
McDermott, L1
Yang, T1
Paiardini, A1
Contestabile, R1
CutruzzolĂ , F1
Insuasty, B1
Tigreros, A1
Orozco, F1
Quiroga, J1
AbonĂ­a, R1
Nogueras, M1
Sanchez, A1
Cobo, J1
Zheng, LW1
Li, Y1
Ge, D1
Zhao, BX2
Liu, YR1
Lv, HS1
Ding, J1
Miao, JY2
Shen, SL1
Zhu, J1
Li, M1

Other Studies

6 other studies available for pyrazole and Lung Neoplasms

ArticleYear
Targeting apoptosis by 1,2-diazole through regulation of EGFR, Bcl-2 and CDK-2 mediated signaling pathway in human non-small cell lung carcinoma A549 cells.
    Gene, 2018, Dec-30, Volume: 679

    Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Prol

2018
Stable and potent analogues derived from the modification of the dicarbonyl moiety of curcumin.
    Biochemistry, 2013, Oct-22, Volume: 52, Issue:42

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Proliferation; Curcumin; Flow Cytometry; Free

2013
A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.
    Oncotarget, 2016, Jan-26, Volume: 7, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Catalytic Domain; Cell Proliferation; Cytoplasm

2016
Synthesis of novel pyrazolic analogues of chalcones and their 3-aryl-4-(3-aryl-4,5-dihydro-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazole derivatives as potential antitumor agents.
    Bioorganic & medicinal chemistry, 2010, Jul-15, Volume: 18, Issue:14

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chalcones; Drug Screening A

2010
Synthesis of novel oxime-containing pyrazole derivatives and discovery of regulators for apoptosis and autophagy in A549 lung cancer cells.
    Bioorganic & medicinal chemistry letters, 2010, Aug-15, Volume: 20, Issue:16

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Crystallography, X-Ray; Drug Evaluati

2010
Synthesis of ferrocenyl pyrazole-containing chiral aminoethanol derivatives and their inhibition against A549 and H322 lung cancer cells.
    European journal of medicinal chemistry, 2012, Volume: 54

    Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Survival; Chemistry Techniques, Synthetic;

2012