pyrazole has been researched along with Liver Diseases in 6 studies
1H-pyrazole : The 1H-tautomer of pyrazole.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyrazole treatment to induce cytochrome P-450 2E1 (CYP2E1) was recently shown to cause liver injury in ob/ob mice but not in lean mice." | 1.34 | S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury. ( Caro, AA; Cederbaum, AI; Dey, A, 2007) |
| "Obesity is a growing health problem in the United States." | 1.34 | Induction of cytochrome P450 2E1 [corrected] promotes liver injury in ob/ob mice. ( Cederbaum, AI; Dey, A, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhuge, J | 1 |
| Cederbaum, AI | 4 |
| Lu, Y | 1 |
| Dey, A | 2 |
| Caro, AA | 1 |
| Wu, D | 1 |
| Cederbaum, A | 1 |
| Lauriault, VV | 1 |
| Khan, S | 1 |
| O'Brien, PJ | 1 |
6 other studies available for pyrazole and Liver Diseases
| Article | Year |
|---|---|
Inhibition of the mitochondrial permeability transition by cyclosporin A prevents pyrazole plus lipopolysaccharide-induced liver injury in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; | 2009 |
Enhancement by pyrazole of lipopolysaccharide-induced liver injury in mice: role of cytochrome P450 2E1 and 2A5.
Topics: Alcohol Dehydrogenase; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Chemical and Drug | 2006 |
S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; DNA Fragmentation; Liver; | 2007 |
Induction of cytochrome P450 2E1 [corrected] promotes liver injury in ob/ob mice.
Topics: Acetone; Animals; Apoptosis; Caspase 3; Catalysis; Chemical and Drug Induced Liver Injury; Cytochrom | 2007 |
Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha-induced liver injury through activation of mitogen-activated protein kinases in mice.
Topics: Animals; Anthracenes; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Glutathione; | 2008 |
Hepatocyte cytotoxicity induced by various hepatotoxins mediated by cytochrome P-450IIE1: protection with diethyldithiocarbamate administration.
Topics: Animals; Carbon Disulfide; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome | 1992 |