pyrazole has been researched along with Leukemia, Myeloid, Acute in 1 studies
1H-pyrazole : The 1H-tautomer of pyrazole.
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "ITD-FLT3 mutation found in many acute myeloid leukemia patients could also be targeted by G-11 as exhibited by its inhibitory effect on MOLM-13 and MV4-11 cell lines." | 1.43 | Novel anticancer compound [trifluoromethyl-substituted pyrazole N-nucleoside] inhibits FLT3 activity to induce differentiation in acute myeloid leukemia cells. ( AbuTayeh, RF; Al-Qudah, MA; Aziz, MA; Rizvi, SA; Saleh, AM; Taha, MO, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saleh, AM | 1 |
| Taha, MO | 1 |
| Aziz, MA | 1 |
| Al-Qudah, MA | 1 |
| AbuTayeh, RF | 1 |
| Rizvi, SA | 1 |
1 other study available for pyrazole and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Novel anticancer compound [trifluoromethyl-substituted pyrazole N-nucleoside] inhibits FLT3 activity to induce differentiation in acute myeloid leukemia cells.
Topics: Apoptosis; Caco-2 Cells; Cell Differentiation; Cell Proliferation; fms-Like Tyrosine Kinase 3; Gene | 2016 |