pyrazole has been researched along with Kidney Diseases in 2 studies
1H-pyrazole : The 1H-tautomer of pyrazole.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cisplatin (a platinum-compound) is a anti-neoplastic drug used in the treatment of various cancers but eventually results in severe adverse effects namely nephrotoxicity or renal disorder through generation of reactive oxygen species (ROS)." | 1.39 | 1,2-Diazole prevents cisplatin-induced nephrotoxicity in experimental rats. ( Guruvayoorappan, C; Kannan, N; Prabhu, VV, 2013) |
| " Early studies by several investigators demonstrated that similar compounds such as alpha, beta-unsaturated aldehyde-cysteine adducts have toxic (carcinostatic) activity against Ehrlich ascites tumor cells implanted in mice." | 1.28 | Nephrotoxicity of the 1:1 acrolein-glutathione adduct in the rat. ( Horvath, JJ; Witmer, CM; Witz, G, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prabhu, VV | 1 |
| Kannan, N | 1 |
| Guruvayoorappan, C | 1 |
| Horvath, JJ | 1 |
| Witmer, CM | 1 |
| Witz, G | 1 |
2 other studies available for pyrazole and Kidney Diseases
| Article | Year |
|---|---|
1,2-Diazole prevents cisplatin-induced nephrotoxicity in experimental rats.
Topics: Animals; Antioxidants; Cisplatin; Creatinine; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Oxi | 2013 |
Nephrotoxicity of the 1:1 acrolein-glutathione adduct in the rat.
Topics: Acrolein; Animals; Disulfiram; Glutathione; Isoxazoles; Kidney Diseases; Kidney Tubules, Proximal; M | 1992 |