Page last updated: 2024-10-20

pyrazole and Gastric Ulcer

pyrazole has been researched along with Gastric Ulcer in 7 studies

1H-pyrazole : The 1H-tautomer of pyrazole.

Research Excerpts

ExcerptRelevanceReference
" The prepared compounds were evaluated for their anti-inflammatory activity using carrageenan-induced rat paw edema and compared to a well-known NSAID, indomethacin as a reference drug."3.75Synthesis and investigation of anti-inflammatory activity and gastric ulcerogenicity of novel nitric oxide-donating pyrazoline derivatives. ( Abdel-Aziz, M; Aly, OM; Farag, HH; Morsy, MA; Shoman, ME, 2009)
" Among the 12 prepared compounds, Compounds 3d, e, i and j exhibited significant anti-inflammatory activity in model of acute inflammation such as carrageenan-induced rat edema paw while compounds 3d and e showed considerable activity in model of chronic inflammation such as adjuvant-induced arthritis and were compared with diclofenac (13."3.75Synthesis and pharmacological evaluation of a novel series of 5-(substituted)aryl-3-(3-coumarinyl)-1-phenyl-2-pyrazolines as novel anti-inflammatory and analgesic agents. ( Aragade, P; Khode, S; Maddi, V; Mamledesai, S; Palkar, M; Ronad, PK; Satyanarayana, D; Thippeswamy, AH, 2009)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's4 (57.14)2.80

Authors

AuthorsStudies
Gedawy, EM1
Kassab, AE1
El Kerdawy, AM1
Fadaly, WAA1
Elshaier, YAMM1
Hassanein, EHM2
Abdellatif, KRA2
Marzouk, AA1
Taher, ES1
Shaykoon, MSA1
Lan, P1
Abd-Allah, WH1
Aboregela, AM1
El-Behairy, MF1
Abdelall, EKA1
Elshemy, HAH1
Philoppes, JN1
Kahk, NM1
Shoman, ME1
Abdel-Aziz, M1
Aly, OM1
Farag, HH1
Morsy, MA1
Khode, S1
Maddi, V1
Aragade, P1
Palkar, M1
Ronad, PK1
Mamledesai, S1
Thippeswamy, AH1
Satyanarayana, D1
Bekhit, AA1
Abdel-Aziem, T1

Other Studies

7 other studies available for pyrazole and Gastric Ulcer

ArticleYear
Design, synthesis and biological evaluation of novel pyrazole sulfonamide derivatives as dual COX-2/5-LOX inhibitors.
    European journal of medicinal chemistry, 2020, Mar-01, Volume: 189

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Arachidonate 5-Lipoxygenase; Cyclo

2020
New 1,2,4-triazole/pyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity, anti-proliferative activities, apoptosis, molecular modeling and nitric oxide relea
    Bioorganic chemistry, 2020, Volume: 98

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Celecoxib; Cell

2020
Design, synthesis, biological evaluation, and computational studies of novel thiazolo-pyrazole hybrids as promising selective COX-2 inhibitors: Implementation of apoptotic genes expression for ulcerogenic liability assessment.
    Bioorganic chemistry, 2021, Volume: 111

    Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Apoptosis; Cyclooxygenase 2 Inhibitors; Dose-R

2021
Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and mol
    Bioorganic chemistry, 2021, Volume: 114

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiotonic Agents; Carrageenan; Cyclooxygenase 2;

2021
Synthesis and investigation of anti-inflammatory activity and gastric ulcerogenicity of novel nitric oxide-donating pyrazoline derivatives.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Edema; Indomethacin; Male; Nitric Oxide; Pyrazoles; Rats; Referen

2009
Synthesis and pharmacological evaluation of a novel series of 5-(substituted)aryl-3-(3-coumarinyl)-1-phenyl-2-pyrazolines as novel anti-inflammatory and analgesic agents.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Drug Design; Edema; Female; Male; Mic

2009
Design, synthesis and biological evaluation of some pyrazole derivatives as anti-inflammatory-antimicrobial agents.
    Bioorganic & medicinal chemistry, 2004, Apr-15, Volume: 12, Issue:8

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Drug Evaluatio

2004