pyrazole has been researched along with Arthritis in 4 studies
1H-pyrazole : The 1H-tautomer of pyrazole.
Arthritis: Acute or chronic inflammation of JOINTS.
Excerpt | Relevance | Reference |
---|---|---|
"In order to discover and develop drug-like anti-inflammatory agents against arthritis, based on "Hit" we found earlier and to overcome drawbacks of toxicity, twelve series of total 89 novel pyrimidine, pyrazolo[4,3-d]pyrimidine and thieno[3,2-d]pyrimidine derivatives were designed, synthesized and screened for their anti-inflammatory activity against NO and toxicity for normal liver cells (LO2)." | 8.02 | Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis. ( Chen, LZ; Huang, X; Liu, MM; Liu, XH; Ma, D; Shi, JB; Shu, HY; Wu, J; Yu, YL, 2021) |
"In order to discover and develop drug-like anti-inflammatory agents against arthritis, based on "Hit" we found earlier and to overcome drawbacks of toxicity, twelve series of total 89 novel pyrimidine, pyrazolo[4,3-d]pyrimidine and thieno[3,2-d]pyrimidine derivatives were designed, synthesized and screened for their anti-inflammatory activity against NO and toxicity for normal liver cells (LO2)." | 4.02 | Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis. ( Chen, LZ; Huang, X; Liu, MM; Liu, XH; Ma, D; Shi, JB; Shu, HY; Wu, J; Yu, YL, 2021) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (75.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Authors | Studies |
---|---|
Chen, LZ | 1 |
Shu, HY | 1 |
Wu, J | 1 |
Yu, YL | 1 |
Ma, D | 1 |
Huang, X | 1 |
Liu, MM | 1 |
Liu, XH | 1 |
Shi, JB | 1 |
GOBEL, P | 1 |
SALVATORI TORRES, F | 1 |
FISCHER, H | 1 |
4 other studies available for pyrazole and Arthritis
Article | Year |
---|---|
Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis.
Topics: Administration, Oral; Animals; Arthritis; Cells, Cultured; Dimerization; Disease Models, Animal; Dos | 2021 |
[Comparative research on the clinical effectiveness of chemically-similar pyrazole derivatives].
Topics: Aminopyrine; Arthritis; Humans; Phenylbutazone; Pyrazoles; Rheumatic Diseases; Treatment Outcome | 1958 |
[Treatment of primary chronic arthritis (rheumatoid arthritis) with the combination of a pyrazol derivative and a steroid].
Topics: Arthritis; Arthritis, Gouty; Arthritis, Rheumatoid; Humans; Phenylbutazone; Prednisone; Pyrazoles | 1963 |
[On irgapyrine, a new drug in parenteral pyrazol therapy of rheumatic polyarthritis].
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Pyrazoles | 1951 |