Page last updated: 2024-10-20

pyrazole and Arthritis

pyrazole has been researched along with Arthritis in 4 studies

1H-pyrazole : The 1H-tautomer of pyrazole.

Arthritis: Acute or chronic inflammation of JOINTS.

Research Excerpts

ExcerptRelevanceReference
"In order to discover and develop drug-like anti-inflammatory agents against arthritis, based on "Hit" we found earlier and to overcome drawbacks of toxicity, twelve series of total 89 novel pyrimidine, pyrazolo[4,3-d]pyrimidine and thieno[3,2-d]pyrimidine derivatives were designed, synthesized and screened for their anti-inflammatory activity against NO and toxicity for normal liver cells (LO2)."8.02Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis. ( Chen, LZ; Huang, X; Liu, MM; Liu, XH; Ma, D; Shi, JB; Shu, HY; Wu, J; Yu, YL, 2021)
"In order to discover and develop drug-like anti-inflammatory agents against arthritis, based on "Hit" we found earlier and to overcome drawbacks of toxicity, twelve series of total 89 novel pyrimidine, pyrazolo[4,3-d]pyrimidine and thieno[3,2-d]pyrimidine derivatives were designed, synthesized and screened for their anti-inflammatory activity against NO and toxicity for normal liver cells (LO2)."4.02Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis. ( Chen, LZ; Huang, X; Liu, MM; Liu, XH; Ma, D; Shi, JB; Shu, HY; Wu, J; Yu, YL, 2021)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Chen, LZ1
Shu, HY1
Wu, J1
Yu, YL1
Ma, D1
Huang, X1
Liu, MM1
Liu, XH1
Shi, JB1
GOBEL, P1
SALVATORI TORRES, F1
FISCHER, H1

Other Studies

4 other studies available for pyrazole and Arthritis

ArticleYear
Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis.
    European journal of medicinal chemistry, 2021, Mar-05, Volume: 213

    Topics: Administration, Oral; Animals; Arthritis; Cells, Cultured; Dimerization; Disease Models, Animal; Dos

2021
[Comparative research on the clinical effectiveness of chemically-similar pyrazole derivatives].
    Arzneimittel-Forschung, 1958, Volume: 8, Issue:11

    Topics: Aminopyrine; Arthritis; Humans; Phenylbutazone; Pyrazoles; Rheumatic Diseases; Treatment Outcome

1958
[Treatment of primary chronic arthritis (rheumatoid arthritis) with the combination of a pyrazol derivative and a steroid].
    La Semana medica, 1963, Mar-07, Volume: 1122

    Topics: Arthritis; Arthritis, Gouty; Arthritis, Rheumatoid; Humans; Phenylbutazone; Prednisone; Pyrazoles

1963
[On irgapyrine, a new drug in parenteral pyrazol therapy of rheumatic polyarthritis].
    Deutsche medizinische Wochenschrift (1946), 1951, Jan-12, Volume: 76, Issue:2

    Topics: Arthritis; Arthritis, Rheumatoid; Humans; Pyrazoles

1951