Compounds > pyrazolanthrone
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pyrazolanthrone and Reperfusion Injury

pyrazolanthrone has been researched along with Reperfusion Injury in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (38.10)29.6817
2010's11 (52.38)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Al-Kandari, N; Al-Maghrebi, M; Al-Saleh, F; Fadel, F; Khashab, F1
Cheng, Y; Liu, Y; Pan, Q; Zhang, Y1
Hong, L; Huang, Z; Li, H; Miao, B; Na, N; Zhang, J; Zhao, D1
Anfinogenova, YD; Atochin, DN; Schepetkin, IA; Shvedova, MV1
Chen, J; Ji, X; Jia, J; Leak, RK; Li, P; Ling, F; Liu, X; Luo, Y; Zhang, L; Zhao, H1
Chen, CX; Li, JM; Li, SX; Zhang, P; Zhao, YN1
Dai, Z; Ge, M; Li, L; Li, Y; Ma, K; Si, J; Wang, S; Yao, S; Yin, J1
Clark, AF; Kim, BJ; Liu, Y; Pang, IH; Silverman, SM; Wordinger, RJ1
Bai, M; Liu, Y; Ma, X; Wang, Y; Yin, D; Zhang, M; Zhao, P1
Bian, HJ; Ji, XP; Li, XX; Liu, XB; Zhang, J; Zhang, Y1
de Borst, MH; Hamming, I; Klok, PA; Kok, RJ; Navis, G; Prakash, J; Sandovici, M; van Goor, H1
Ban, K; Kozar, RA; Santora, R1
Chen, L; Cui, X; Ding, Q; Du, Z; Gao, Y; Wang, X; Xu, D1
Che, JP; Liu, M; Peng, B; Wang, GC; Wu, YC; Xu, YF; Yan, Y; Zhang, HM; Zheng, JH1
Dai, YY; Fang, ZX; Qiu, XX; Song, ZJ; Wang, WT1
Guan, QH; Hao, ZB; Pei, DS; Xu, TL; Zhang, GY; Zhang, QG1
Cao, G; Chen, J; Gao, Y; Graham, SH; Luo, Y; Signore, AP; Sun, F; Yin, W; Yin, XM1
Kim, SE; Lee, KH; Lee, YS1
Guan, QH; Ji, HX; Pei, DS; Wang, Y; Xing, SH1
Arthur, PG; Bogoyevitch, MA1
Farivar, AS; McCourtie, AS; Merry, HE; Mulligan, MS; Wolf, PS1

Reviews

2 review(s) available for pyrazolanthrone and Reperfusion Injury

ArticleYear
[JUN N-TERMINAL KINASES AND THEIR PHARMACOLOGICAL MODULATION OF ISCHE-MIC AND REPERFUSION INJURY OF THE BRAIN].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2017, Volume: 103, Issue:3

    Topics: Acetonitriles; Animals; Anthracenes; Benzothiazoles; Brain; Brain Ischemia; Gene Expression Regulation; Ginsenosides; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 10; Neuroprotective Agents; Oximes; Plant Extracts; Protein Kinase Inhibitors; Quinoxalines; Reperfusion Injury; Signal Transduction

2017
Inhibitors of c-Jun N-terminal kinases: JuNK no more?
    Biochimica et biophysica acta, 2008, Volume: 1784, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Anthracenes; Apoptosis; Humans; Ischemia; JNK Mitogen-Activated Protein Kinases; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Kinase Inhibitors; Reperfusion Injury; Signal Transduction; Virus Diseases

2008

Other Studies

19 other study(ies) available for pyrazolanthrone and Reperfusion Injury

ArticleYear
JNK inhibition alleviates oxidative DNA damage, germ cell apoptosis, and mitochondrial dysfunction in testicular ischemia reperfusion injury.
    Acta biochimica et biophysica Sinica, 2020, Aug-05, Volume: 52, Issue:8

    Topics: Animals; Anthracenes; Apoptosis; DNA Damage; Germ Cells; Male; MAP Kinase Kinase 4; Mitochondria; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spermatogenesis; Testicular Diseases; Testis

2020
Effects of SP600125 and hypothermic machine perfusion on livers donated after cardiac death in a pig allograft transplantation model.
    European journal of medical research, 2021, Feb-05, Volume: 26, Issue:1

    Topics: Allografts; Animals; Anthracenes; Cold Temperature; Death; Disease Models, Animal; Liver Transplantation; Organ Preservation; Perfusion; Reperfusion Injury; Swine; Swine, Miniature

2021
Renoprotective effect of erythropoietin via modulation of the STAT6/MAPK/NF-κB pathway in ischemia/reperfusion injury after renal transplantation.
    International journal of molecular medicine, 2018, Volume: 41, Issue:1

    Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; Erythropoietin; Gene Expression Regulation; Humans; Imidazoles; Interferon-gamma; Kidney; Kidney Transplantation; Lentivirus; MAP Kinase Kinase 4; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrimidines; Rats; Reperfusion Injury; RNA, Small Interfering; Signal Transduction; STAT6 Transcription Factor

2018
Peroxiredoxin 2 battles poly(ADP-ribose) polymerase 1- and p53-dependent prodeath pathways after ischemic injury.
    Stroke, 2013, Volume: 44, Issue:4

    Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Cells, Cultured; DNA Damage; Humans; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neurons; Peroxiredoxins; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Tumor Suppressor Protein p53

2013
Hypertension-mediated enhancement of JNK activation in association with endoplasmic reticulum stress in rat model hippocampus with cerebral ischemia-reperfusion.
    Genetics and molecular research : GMR, 2015, Sep-21, Volume: 14, Issue:3

    Topics: Animals; Anthracenes; Brain Ischemia; CA1 Region, Hippocampal; Disease Models, Animal; Endoplasmic Reticulum Stress; Enzyme Activation; Heat-Shock Proteins; Hippocampus; Hypertension; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reperfusion Injury; Transcription Factor CHOP

2015
Transforming growth-beta 1 contributes to isoflurane postconditioning against cerebral ischemia-reperfusion injury by regulating the c-Jun N-terminal kinase signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 78

    Topics: Animals; Anthracenes; Behavior, Animal; Brain Ischemia; CA1 Region, Hippocampal; In Situ Nick-End Labeling; Ischemic Postconditioning; Isoflurane; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Phosphorylation; Pyrazoles; Quinolines; Rats, Sprague-Dawley; Reperfusion Injury; Transforming Growth Factor beta1

2016
In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells.
    Molecular neurodegeneration, 2016, Apr-21, Volume: 11

    Topics: Animals; Anthracenes; Apoptosis; Disease Models, Animal; Female; Intraocular Pressure; JNK Mitogen-Activated Protein Kinases; Neuroprotective Agents; Rats, Sprague-Dawley; Reperfusion Injury; Retina; Retinal Diseases; Retinal Ganglion Cells

2016
Inhibition of c-Jun N-terminal kinase signaling suppresses skin flap apoptosis in a rat ischemia and/or reperfusion model.
    The Journal of surgical research, 2016, Volume: 206, Issue:2

    Topics: Animals; Anthracenes; Apoptosis; Biomarkers; JNK Mitogen-Activated Protein Kinases; Male; Phosphorylation; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Skin; Sodium Chloride; Surgical Flaps

2016
Inhibition of the activity of Rho-kinase reduces cardiomyocyte apoptosis in heart ischemia/reperfusion via suppressing JNK-mediated AIF translocation.
    Clinica chimica acta; international journal of clinical chemistry, 2009, Volume: 401, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anthracenes; Apoptosis; Apoptosis Inducing Factor; Female; MAP Kinase Kinase 4; Myocardial Infarction; Myocytes, Cardiac; Protein Kinase Inhibitors; Rats; Rats, Wistar; Reperfusion Injury; rho-Associated Kinases

2009
c-Jun NH2-terminal kinase is crucially involved in renal tubulo-interstitial inflammation.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:3

    Topics: Adolescent; Adult; Animals; Anthracenes; Blotting, Western; Cell Line; Chemokine CCL2; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Female; Gene Expression; Humans; Immunohistochemistry; Inflammation; JNK Mitogen-Activated Protein Kinases; Kidney Diseases; Kidney Tubules; Macrophages; Male; Middle Aged; Nephritis, Interstitial; Protein Kinase Inhibitors; Rats; Rats, Wistar; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Young Adult

2009
Enteral arginine modulates inhibition of AP-1/c-Jun by SP600125 in the postischemic gut.
    Molecular and cellular biochemistry, 2011, Volume: 347, Issue:1-2

    Topics: Amidines; Animals; Anthracenes; Arginine; Benzylamines; DNA; Enteral Nutrition; Gene Silencing; Inflammation; Intestine, Small; Nitric Oxide Synthase Type II; Protein Binding; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Small Interfering; Transcription Factor AP-1

2011
Effect of donor JNK signal transduction inhibition on transplant outcome in brain dead rat model.
    Inflammation, 2012, Volume: 35, Issue:1

    Topics: Animals; Anthracenes; Brain Death; Graft Rejection; Graft Survival; JNK Mitogen-Activated Protein Kinases; Kidney Transplantation; MAP Kinase Signaling System; Rats; Rats, Inbred Lew; Reperfusion Injury

2012
Protective effects of SP600125 on renal ischemia-reperfusion injury in rats.
    The Journal of surgical research, 2011, Volume: 169, Issue:1

    Topics: Animals; Anthracenes; Apoptosis; Cytokines; Enzyme Inhibitors; Ischemia; Kidney; Male; MAP Kinase Kinase 4; Models, Animal; Phosphorylation; Rats; Rats, Inbred F344; Reactive Oxygen Species; Regional Blood Flow; Reperfusion Injury; Treatment Outcome

2011
[Protective effects and mechanism of SP600125 on lung ischemia/reperfusion injury in rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2012, Volume: 28, Issue:3

    Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Lung; MAP Kinase Signaling System; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reperfusion Injury

2012
The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways.
    Brain research, 2005, Feb-21, Volume: 1035, Issue:1

    Topics: Analysis of Variance; Animals; Anthracenes; Blotting, Western; Cell Count; Cell Death; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Immunoprecipitation; Ischemic Attack, Transient; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Neurons; Neuroprotective Agents; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Staining and Labeling; Time Factors

2005
Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2005, Volume: 25, Issue:6

    Topics: 14-3-3 Proteins; Animals; Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Brain Ischemia; Carrier Proteins; Cerebral Infarction; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Mice; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reperfusion Injury; Signal Transduction

2005
SP600125, a selective JNK inhibitor, aggravates hepatic ischemia-reperfusion injury.
    Experimental & molecular medicine, 2006, Aug-31, Volume: 38, Issue:4

    Topics: Animals; Anthracenes; Chemokines; Liver; Male; MAP Kinase Kinase 4; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Oxidative Stress; Reperfusion Injury

2006
SP600125, a selective JNK inhibitor, protects ischemic renal injury via suppressing the extrinsic pathways of apoptosis.
    Life sciences, 2007, May-08, Volume: 80, Issue:22

    Topics: Animals; Anthracenes; Apoptosis; Disease Models, Animal; JNK Mitogen-Activated Protein Kinases; Kidney; Kidney Diseases; Necrosis; Protective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction

2007
Stress-activated protein kinase inhibition to ameliorate lung ischemia reperfusion injury.
    The Journal of thoracic and cardiovascular surgery, 2008, Volume: 135, Issue:3

    Topics: Animals; Anthracenes; Blotting, Western; Bronchoalveolar Lavage Fluid; Butadienes; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Immunohistochemistry; Inflammation Mediators; Lung Diseases; Male; Mitogen-Activated Protein Kinases; Nitriles; Oxidative Stress; Peroxidase; Phosphorylation; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion Injury; Sensitivity and Specificity

2008