Page last updated: 2024-08-18

pyrazolanthrone and Neoplasms

pyrazolanthrone has been researched along with Neoplasms in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (37.50)29.6817
2010's8 (50.00)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Gehringer, M; Koch, P; Laufer, SA1
Bu, F; Ouyang, L; Pan, X; Pei, J; Shuai, W; Wang, A; Wang, G; Wu, Y; Zhao, M; Zhu, Y1
Cho, Y; Jeon, SD; Kim, C; Kim, KY; Kim, MG; Lee, HS; Yoon, J; Yoon, MJ1
Kim, J; Kim, KS; Lee, HM1
Liu, Y; Tan, WF; Wang, J; Yang, J; Zhang, X1
Cao, Q; Chen, GL; Fang, WH; Jiang, XR; Li, HH; Li, M; Li, Y; Liu, X; Ping, GF; Wang, LH; Wang, S; Wu, CF; Yang, JY1
Fang, B; Guo, W; Liu, J; Lu, Y; Wang, L; Wei, X; Wu, S; Xu, B1
Fu, K; Li, B; Mu, C; Ren, H; Wang, D; Wang, G1
Jeon, HW; Kim, WH; Lee, KJ; Lee, SH; Lee, YM1
Davies, C; Tournier, C1
Antoccia, A; Berardinelli, F; Castedo, M; Galluzzi, L; Harper, F; Jemaà, M; Kepp, O; Kroemer, G; Lissa, D; Malik, SA; Mariño, G; Pierron, G; Rello-Varona, S; Schlemmer, F; Senovilla, L; Tailler, M; Vitale, I1
Bilter, GK; Boluro-Ajayi, M; Ennis, BW; Fultz, KE; Smith, KA; Stein, B; Westwick, JK; Zhu, D1
Bach, LA; Fu, P; Thompson, JA1
Jang, YS; Kim, BS; Kook, SH; Lee, HJ; Lee, JC; Lee, KY; Lee, SA; Son, YO1
Derijard, B; Giorgelli, JL; Martial, S; Renaudo, A; Soriani, O1

Reviews

2 review(s) available for pyrazolanthrone and Neoplasms

ArticleYear
Inhibitors of c-Jun N-terminal kinases: an update.
    Journal of medicinal chemistry, 2015, Jan-08, Volume: 58, Issue:1

    Topics: Central Nervous System Diseases; Humans; Inflammation; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Models, Molecular; Molecular Structure; Neoplasms; Protein Binding; Protein Kinase Inhibitors

2015
Exploring the function of the JNK (c-Jun N-terminal kinase) signalling pathway in physiological and pathological processes to design novel therapeutic strategies.
    Biochemical Society transactions, 2012, Volume: 40, Issue:1

    Topics: Animals; Anthracenes; Apoptosis; Brain; Enzyme Activation; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Neoplasms; Neurodegenerative Diseases

2012

Other Studies

14 other study(ies) available for pyrazolanthrone and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Unraveling the Design and Discovery of c-Jun N-Terminal Kinase Inhibitors and Their Therapeutic Potential in Human Diseases.
    Journal of medicinal chemistry, 2022, 03-10, Volume: 65, Issue:5

    Topics: Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Neoplasms; Phosphorylation; Protein Isoforms

2022
A JUN N-terminal kinase inhibitor induces ectodomain shedding of the cancer-associated membrane protease Prss14/epithin via protein kinase CβII.
    The Journal of biological chemistry, 2020, 05-15, Volume: 295, Issue:20

    Topics: Anthracenes; Cell Line, Tumor; Humans; MAP Kinase Kinase 4; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Protein Kinase C beta; Protein Kinase Inhibitors; Protein Transport; Serine Endopeptidases; Signal Transduction; Tetradecanoylphorbol Acetate

2020
A comparative study of the effects of inhibitory cytokines on human natural killer cells and the mechanistic features of transforming growth factor-beta.
    Cellular immunology, 2014, Volume: 290, Issue:1

    Topics: Anthracenes; Cell Line; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; Humans; Interferon-gamma; Interleukin-10; Interleukin-2; Interleukin-4; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Killer Cells, Natural; Lymphocyte Activation; MAP Kinase Kinase 1; Neoplasms; Phosphorylation; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-myb; Proto-Oncogene Proteins c-myc; Receptors, Androgen; Signal Transduction; Syk Kinase; Transcription Factor AP-1; Transforming Growth Factor beta; Tumor Escape

2014
JNK is required for maintaining the tumor-initiating cell-like properties of acquired chemoresistant human cancer cells.
    Acta pharmacologica Sinica, 2015, Volume: 36, Issue:9

    Topics: Anthracenes; Drug Resistance, Neoplasm; Hedgehog Proteins; Humans; K562 Cells; KB Cells; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Neoplasms; Neoplastic Stem Cells; RNA Interference; RNA, Small Interfering

2015
SL4, a chalcone-based compound, induces apoptosis in human cancer cells by activation of the ROS/MAPK signalling pathway.
    Cell proliferation, 2015, Volume: 48, Issue:6

    Topics: Animals; Anthracenes; Apoptosis; bcl-X Protein; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Enzyme Activation; Female; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1; Imidazoles; Inhibitor of Apoptosis Proteins; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Pyridines; Reactive Oxygen Species; Survivin; X-Linked Inhibitor of Apoptosis Protein

2015
Inhibiting JNK dephosphorylation and induction of apoptosis by novel anticancer agent NSC-741909 in cancer cells.
    The Journal of biological chemistry, 2009, Jun-19, Volume: 284, Issue:25

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Base Sequence; Cell Line, Tumor; DNA Primers; Drug Screening Assays, Antitumor; Enzyme Activation; Female; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Molecular Structure; Neoplasms; Phosphorylation

2009
DJ-1, a cancer and Parkinson's disease associated protein, regulates autophagy through JNK pathway in cancer cells.
    Cancer letters, 2010, Nov-01, Volume: 297, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Anthracenes; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Neoplasms; Oncogene Proteins; Protein Deglycase DJ-1; Protein Kinase Inhibitors; RNA Interference; Sequestosome-1 Protein; Signal Transduction; Transfection

2010
Attenuated expression and function of the RECK tumor suppressor under hypoxic conditions is mediated by the MAPK signaling pathways.
    Archives of pharmacal research, 2011, Volume: 34, Issue:1

    Topics: Anthracenes; Cell Hypoxia; Cell Line, Tumor; Down-Regulation; Flavonoids; GPI-Linked Proteins; HEK293 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Mitogen-Activated Protein Kinases; Neoplasms; Promoter Regions, Genetic; Protein Binding; Pyridines; Response Elements; RNA, Messenger; Signal Transduction

2011
Selective killing of p53-deficient cancer cells by SP600125.
    EMBO molecular medicine, 2012, Volume: 4, Issue:6

    Topics: Animals; Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Mice; Microscopy, Video; Neoplasms; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2012
Inhibition of tumor growth, angiogenesis, and tumor cell proliferation by a small molecule inhibitor of c-Jun N-terminal kinase.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Anthracenes; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Endothelial Cells; Female; Flow Cytometry; G2 Phase; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms

2005
Promotion of cancer cell migration: an insulin-like growth factor (IGF)-independent action of IGF-binding protein-6.
    The Journal of biological chemistry, 2007, Aug-03, Volume: 282, Issue:31

    Topics: Anthracenes; Cell Movement; Humans; Imidazoles; Insulin-Like Growth Factor Binding Protein 6; Insulin-Like Growth Factor I; Ligands; MAP Kinase Signaling System; Mutation; Neoplasms; p38 Mitogen-Activated Protein Kinases; Protein Binding; Protein Structure, Tertiary; Pyridines; Rhabdomyosarcoma; Tumor Cells, Cultured

2007
Inhibition of c-Jun N-terminal kinase sensitizes tumor cells to flavonoid-induced apoptosis through down-regulation of JunD.
    Toxicology and applied pharmacology, 2008, Mar-15, Volume: 227, Issue:3

    Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; DNA; Flavonoids; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred BALB C; Neoplasms; Phosphorylation; Plant Extracts; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Rhus; RNA, Small Interfering; Transcription Factor AP-1; Transfection

2008
SP600125 inhibits Kv channels through a JNK-independent pathway in cancer cells.
    Biochemical and biophysical research communications, 2008, Feb-22, Volume: 366, Issue:4

    Topics: Anthracenes; Cell Line, Tumor; Cinnamates; Cyclopropanes; Extracellular Signal-Regulated MAP Kinases; Humans; Ion Channel Gating; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Neoplasms; p38 Mitogen-Activated Protein Kinases; Potassium Channels, Voltage-Gated

2008