Page last updated: 2024-08-18

pyrazolanthrone and Lung Neoplasms

pyrazolanthrone has been researched along with Lung Neoplasms in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (16.67)29.6817
2010's14 (77.78)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Furuya, T; Kojima, H; Masuda, Y; Nagano, T; Okabe, T; Okamoto, M; Saito, N1
Hu, F; Jing, Y; Liu, D; Lv, W; Xin, T1
Liu, L; Wang, Y; Zhang, H; Zhang, N; Zhao, Z; Zhou, Y1
Hedrick, E; Mohankumar, K; Safe, S1
Chen, X; Liu, C; Wu, J; Ying, M; Zhao, P; Zhao, R; Zhou, N1
Fan, C; Jiang, B; Liu, H; Shi, X1
Almasi, S; Clements, DR; El Hiani, Y; Gujar, S; Long, CY; Sterea, A1
Kitanaka, C; Okada, M; Sato, A; Seino, M; Seino, S; Shibuya, K; Suzuki, S; Watanabe, E1
Ju, Y; Xu, T; Yu, A; Zhang, H1
Brantley-Sieders, D; Chen, J; Ma, Y; Song, W; Wang, J1
Chang, LF; Chiou, TW; Chou, CW; Chuang, HM; Harn, HJ; Hsieh, ST; Huang, AY; Kuo, YH; Lin, SZ1
Hwang, JH; Jang, IS; Jo, E; Joo, JC; Kim, DJ; Kim, YR; Lee, KB; Park, SJ1
Alam, S; Janciauskiene, S; Li, Z; Mahadeva, R; Sandstrom, CS; Wang, J1
Arora, H; Park, AK; Park, WY; Qureshi, R1
Im, SY; Kim, HA; Kim, KJ; Lee, HK; Seo, KH1
Kang, JH; Kim, SY; Lee, CH; Lee, HJ; Oh, SH; Park, MK; You, HJ1
Broaddus, VC; Liu, W; Vivo, C1
Miyamoto-Yamasaki, Y; Tachibana, H; Yamada, K; Yamasaki, M1

Other Studies

18 other study(ies) available for pyrazolanthrone and Lung Neoplasms

ArticleYear
Virtual screening and further development of novel ALK inhibitors.
    Bioorganic & medicinal chemistry, 2011, May-15, Volume: 19, Issue:10

    Topics: Anaplastic Lymphoma Kinase; Carcinoma, Non-Small-Cell Lung; Drug Design; Humans; Lung Neoplasms; Models, Molecular; Protein Kinase Inhibitors; Receptor Protein-Tyrosine Kinases

2011
ROCK1 knockdown inhibits non-small-cell lung cancer progression by activating the LATS2-JNK signaling pathway.
    Aging, 2020, 06-17, Volume: 12, Issue:12

    Topics: A549 Cells; Anthracenes; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Disease Progression; Gene Knockdown Techniques; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; MAP Kinase Signaling System; Mitochondria; Mitochondrial Dynamics; Protein Serine-Threonine Kinases; rho-Associated Kinases; RNA, Small Interfering; Tumor Suppressor Proteins

2020
37LRP induces invasion in hypoxic lung adenocarcinoma cancer cells A549 through the JNK/ERK/c-Jun signaling cascade.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:6

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Anthracenes; Butadienes; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; MAP Kinase Kinase 4; MAP Kinase Signaling System; Nitriles; Phosphorylation; Receptors, Laminin

2017
TGFβ-Induced Lung Cancer Cell Migration Is NR4A1-Dependent.
    Molecular cancer research : MCR, 2018, Volume: 16, Issue:12

    Topics: A549 Cells; Active Transport, Cell Nucleus; Anthracenes; Cell Line, Tumor; Cell Movement; Fatty Acids, Unsaturated; Humans; Lung Neoplasms; MAP Kinase Signaling System; Nuclear Receptor Subfamily 4, Group A, Member 1; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta

2018
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells.
    Molecular pharmaceutics, 2018, 11-05, Volume: 15, Issue:11

    Topics: A549 Cells; Anthracenes; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Drug Synergism; Feedback, Physiological; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Oleanolic Acid; Phosphorylation; Saponins; Tumor Suppressor Protein p53

2018
ZCCHC9 promotes proliferation and invasion of lung cancer through regulating the JNK pathway.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:6

    Topics: A549 Cells; Anthracenes; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cytoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Lymphatic Metastasis; Male; MAP Kinase Signaling System; Middle Aged; Nuclear Proteins; RNA-Binding Proteins

2019
TRPM2 Silencing Causes G2/M Arrest and Apoptosis in Lung Cancer Cells via Increasing Intracellular ROS and RNS Levels and Activating the JNK Pathway.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2019, Volume: 52, Issue:4

    Topics: Animals; Anthracenes; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Damage; G2 Phase Cell Cycle Checkpoints; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; M Phase Cell Cycle Checkpoints; MAP Kinase Signaling System; Mice; Mice, SCID; Reactive Nitrogen Species; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; TRPM Cation Channels

2019
Specific role of JNK in the maintenance of the tumor-initiating capacity of A549 human non-small cell lung cancer cells.
    Oncology reports, 2013, Volume: 30, Issue:4

    Topics: Animals; Anthracenes; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Heterografts; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Neoplasm Transplantation; RNA Interference; RNA, Small Interfering

2013
FOXO1-dependent DNA damage repair is regulated by JNK in lung cancer cells.
    International journal of oncology, 2014, Volume: 44, Issue:4

    Topics: Anthracenes; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase Inhibitor p27; DNA Damage; DNA Repair; Forkhead Box Protein O1; Forkhead Transcription Factors; G2 Phase Cell Cycle Checkpoints; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Membrane Proteins; Methylnitronitrosoguanidine; Nuclear Proteins; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Transcription, Genetic; Transcriptional Activation

2014
JNK signaling mediates EPHA2-dependent tumor cell proliferation, motility, and cancer stem cell-like properties in non-small cell lung cancer.
    Cancer research, 2014, May-01, Volume: 74, Issue:9

    Topics: Aldehyde Dehydrogenase; Animals; Anthracenes; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Knockdown Techniques; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; MAP Kinase Signaling System; Mice; Mice, Nude; Neoplasm Transplantation; Neoplastic Stem Cells; Phosphorylation; Protein Processing, Post-Translational; Receptor, EphA2; Tumor Burden

2014
Taiwanin A targets non-steroidal anti-inflammatory drug-activated gene-1 in human lung carcinoma.
    Fitoterapia, 2014, Volume: 99

    Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Furans; Growth Differentiation Factor 15; Humans; JNK Mitogen-Activated Protein Kinases; Lignans; Lung Neoplasms; MAP Kinase Signaling System; Mice, Inbred BALB C; Mice, Nude; Protein Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2014
Cordycepin induces apoptosis by caveolin-1-mediated JNK regulation of Foxo3a in human lung adenocarcinoma.
    Oncotarget, 2017, Feb-14, Volume: 8, Issue:7

    Topics: A549 Cells; Adenocarcinoma; Animals; Anthracenes; Apoptosis; Blotting, Western; Caveolin 1; Cell Line, Tumor; Deoxyadenosines; Forkhead Box Protein O3; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Ontology; Gene Regulatory Networks; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Phosphorylation; RNA Interference; Signal Transduction; Xenograft Model Antitumor Assays

2017
Oxidized {alpha}1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 297, Issue:2

    Topics: alpha 1-Antitrypsin; Animals; Anthracenes; Bronchi; Bronchoalveolar Lavage Fluid; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chemokine CCL2; Emphysema; Female; Humans; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Mice; Mice, Inbred C57BL; NF-kappa B p50 Subunit; Oxidants; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Protein Conformation; Respiratory Mucosa

2009
Coordinated regulation of ATF2 by miR-26b in γ-irradiated lung cancer cells.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Activating Transcription Factor 2; Anthracenes; Cell Line, Tumor; Gamma Rays; Humans; Lung Neoplasms; MicroRNAs; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-jun; Signal Transduction

2011
PTEN/MAPK pathways play a key role in platelet-activating factor-induced experimental pulmonary tumor metastasis.
    FEBS letters, 2012, Dec-14, Volume: 586, Issue:24

    Topics: Androstadienes; Animals; Anthracenes; Butadienes; Cell Line; Humans; Imidazoles; Lung Neoplasms; MAP Kinase Signaling System; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyridines; Wortmannin

2012
Transglutaminase-2 induces N-cadherin expression in TGF-β1-induced epithelial mesenchymal transition via c-Jun-N-terminal kinase activation by protein phosphatase 2A down-regulation.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:7

    Topics: Animals; Anthracenes; Blotting, Western; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cells, Cultured; Cystamine; Enzyme Activation; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; GTP-Binding Proteins; HEK293 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Mice; Mice, SCID; Protein Glutamine gamma Glutamyltransferase 2; Protein Phosphatase 2; RNA Interference; Transforming Growth Factor beta1; Transglutaminases; Transplantation, Heterologous

2013
c-Jun N-terminal kinase contributes to apoptotic synergy induced by tumor necrosis factor-related apoptosis-inducing ligand plus DNA damage in chemoresistant, p53 inactive mesothelioma cells.
    The Journal of biological chemistry, 2003, Jul-11, Volume: 278, Issue:28

    Topics: Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase 9; Caspases; Cell Survival; DNA Damage; Dose-Response Relationship, Radiation; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Etoposide; Genes, Dominant; Genes, p53; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Membrane Glycoproteins; Mesothelioma; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Recombinant Proteins; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Ultraviolet Rays

2003
Induction of endoreduplication by a JNK inhibitor SP600125 in human lung carcinoma A 549 cells.
    Cell biology international, 2007, Volume: 31, Issue:12

    Topics: Anthracenes; Carcinoma; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; DNA; DNA Replication; G2 Phase; Gene Expression Regulation; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Polyploidy; Protein Binding; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Tumor Suppressor Protein p53

2007