Compounds > pyrazolanthrone
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pyrazolanthrone and Injury, Ischemia-Reperfusion

pyrazolanthrone has been researched along with Injury, Ischemia-Reperfusion in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (38.10)29.6817
2010's11 (52.38)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Al-Kandari, N; Al-Maghrebi, M; Al-Saleh, F; Fadel, F; Khashab, F1
Cheng, Y; Liu, Y; Pan, Q; Zhang, Y1
Hong, L; Huang, Z; Li, H; Miao, B; Na, N; Zhang, J; Zhao, D1
Anfinogenova, YD; Atochin, DN; Schepetkin, IA; Shvedova, MV1
Chen, J; Ji, X; Jia, J; Leak, RK; Li, P; Ling, F; Liu, X; Luo, Y; Zhang, L; Zhao, H1
Chen, CX; Li, JM; Li, SX; Zhang, P; Zhao, YN1
Dai, Z; Ge, M; Li, L; Li, Y; Ma, K; Si, J; Wang, S; Yao, S; Yin, J1
Clark, AF; Kim, BJ; Liu, Y; Pang, IH; Silverman, SM; Wordinger, RJ1
Bai, M; Liu, Y; Ma, X; Wang, Y; Yin, D; Zhang, M; Zhao, P1
Bian, HJ; Ji, XP; Li, XX; Liu, XB; Zhang, J; Zhang, Y1
de Borst, MH; Hamming, I; Klok, PA; Kok, RJ; Navis, G; Prakash, J; Sandovici, M; van Goor, H1
Ban, K; Kozar, RA; Santora, R1
Chen, L; Cui, X; Ding, Q; Du, Z; Gao, Y; Wang, X; Xu, D1
Che, JP; Liu, M; Peng, B; Wang, GC; Wu, YC; Xu, YF; Yan, Y; Zhang, HM; Zheng, JH1
Dai, YY; Fang, ZX; Qiu, XX; Song, ZJ; Wang, WT1
Guan, QH; Hao, ZB; Pei, DS; Xu, TL; Zhang, GY; Zhang, QG1
Cao, G; Chen, J; Gao, Y; Graham, SH; Luo, Y; Signore, AP; Sun, F; Yin, W; Yin, XM1
Kim, SE; Lee, KH; Lee, YS1
Guan, QH; Ji, HX; Pei, DS; Wang, Y; Xing, SH1
Arthur, PG; Bogoyevitch, MA1
Farivar, AS; McCourtie, AS; Merry, HE; Mulligan, MS; Wolf, PS1

Reviews

2 review(s) available for pyrazolanthrone and Injury, Ischemia-Reperfusion

ArticleYear
[JUN N-TERMINAL KINASES AND THEIR PHARMACOLOGICAL MODULATION OF ISCHE-MIC AND REPERFUSION INJURY OF THE BRAIN].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2017, Volume: 103, Issue:3

    Topics: Acetonitriles; Animals; Anthracenes; Benzothiazoles; Brain; Brain Ischemia; Gene Expression Regulation; Ginsenosides; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 10; Neuroprotective Agents; Oximes; Plant Extracts; Protein Kinase Inhibitors; Quinoxalines; Reperfusion Injury; Signal Transduction

2017
Inhibitors of c-Jun N-terminal kinases: JuNK no more?
    Biochimica et biophysica acta, 2008, Volume: 1784, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Anthracenes; Apoptosis; Humans; Ischemia; JNK Mitogen-Activated Protein Kinases; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Kinase Inhibitors; Reperfusion Injury; Signal Transduction; Virus Diseases

2008

Other Studies

19 other study(ies) available for pyrazolanthrone and Injury, Ischemia-Reperfusion

ArticleYear
JNK inhibition alleviates oxidative DNA damage, germ cell apoptosis, and mitochondrial dysfunction in testicular ischemia reperfusion injury.
    Acta biochimica et biophysica Sinica, 2020, Aug-05, Volume: 52, Issue:8

    Topics: Animals; Anthracenes; Apoptosis; DNA Damage; Germ Cells; Male; MAP Kinase Kinase 4; Mitochondria; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spermatogenesis; Testicular Diseases; Testis

2020
Effects of SP600125 and hypothermic machine perfusion on livers donated after cardiac death in a pig allograft transplantation model.
    European journal of medical research, 2021, Feb-05, Volume: 26, Issue:1

    Topics: Allografts; Animals; Anthracenes; Cold Temperature; Death; Disease Models, Animal; Liver Transplantation; Organ Preservation; Perfusion; Reperfusion Injury; Swine; Swine, Miniature

2021
Renoprotective effect of erythropoietin via modulation of the STAT6/MAPK/NF-κB pathway in ischemia/reperfusion injury after renal transplantation.
    International journal of molecular medicine, 2018, Volume: 41, Issue:1

    Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; Erythropoietin; Gene Expression Regulation; Humans; Imidazoles; Interferon-gamma; Kidney; Kidney Transplantation; Lentivirus; MAP Kinase Kinase 4; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrimidines; Rats; Reperfusion Injury; RNA, Small Interfering; Signal Transduction; STAT6 Transcription Factor

2018
Peroxiredoxin 2 battles poly(ADP-ribose) polymerase 1- and p53-dependent prodeath pathways after ischemic injury.
    Stroke, 2013, Volume: 44, Issue:4

    Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Cells, Cultured; DNA Damage; Humans; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neurons; Peroxiredoxins; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Tumor Suppressor Protein p53

2013
Hypertension-mediated enhancement of JNK activation in association with endoplasmic reticulum stress in rat model hippocampus with cerebral ischemia-reperfusion.
    Genetics and molecular research : GMR, 2015, Sep-21, Volume: 14, Issue:3

    Topics: Animals; Anthracenes; Brain Ischemia; CA1 Region, Hippocampal; Disease Models, Animal; Endoplasmic Reticulum Stress; Enzyme Activation; Heat-Shock Proteins; Hippocampus; Hypertension; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reperfusion Injury; Transcription Factor CHOP

2015
Transforming growth-beta 1 contributes to isoflurane postconditioning against cerebral ischemia-reperfusion injury by regulating the c-Jun N-terminal kinase signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 78

    Topics: Animals; Anthracenes; Behavior, Animal; Brain Ischemia; CA1 Region, Hippocampal; In Situ Nick-End Labeling; Ischemic Postconditioning; Isoflurane; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Phosphorylation; Pyrazoles; Quinolines; Rats, Sprague-Dawley; Reperfusion Injury; Transforming Growth Factor beta1

2016
In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells.
    Molecular neurodegeneration, 2016, Apr-21, Volume: 11

    Topics: Animals; Anthracenes; Apoptosis; Disease Models, Animal; Female; Intraocular Pressure; JNK Mitogen-Activated Protein Kinases; Neuroprotective Agents; Rats, Sprague-Dawley; Reperfusion Injury; Retina; Retinal Diseases; Retinal Ganglion Cells

2016
Inhibition of c-Jun N-terminal kinase signaling suppresses skin flap apoptosis in a rat ischemia and/or reperfusion model.
    The Journal of surgical research, 2016, Volume: 206, Issue:2

    Topics: Animals; Anthracenes; Apoptosis; Biomarkers; JNK Mitogen-Activated Protein Kinases; Male; Phosphorylation; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Skin; Sodium Chloride; Surgical Flaps

2016
Inhibition of the activity of Rho-kinase reduces cardiomyocyte apoptosis in heart ischemia/reperfusion via suppressing JNK-mediated AIF translocation.
    Clinica chimica acta; international journal of clinical chemistry, 2009, Volume: 401, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anthracenes; Apoptosis; Apoptosis Inducing Factor; Female; MAP Kinase Kinase 4; Myocardial Infarction; Myocytes, Cardiac; Protein Kinase Inhibitors; Rats; Rats, Wistar; Reperfusion Injury; rho-Associated Kinases

2009
c-Jun NH2-terminal kinase is crucially involved in renal tubulo-interstitial inflammation.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:3

    Topics: Adolescent; Adult; Animals; Anthracenes; Blotting, Western; Cell Line; Chemokine CCL2; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Female; Gene Expression; Humans; Immunohistochemistry; Inflammation; JNK Mitogen-Activated Protein Kinases; Kidney Diseases; Kidney Tubules; Macrophages; Male; Middle Aged; Nephritis, Interstitial; Protein Kinase Inhibitors; Rats; Rats, Wistar; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Young Adult

2009
Enteral arginine modulates inhibition of AP-1/c-Jun by SP600125 in the postischemic gut.
    Molecular and cellular biochemistry, 2011, Volume: 347, Issue:1-2

    Topics: Amidines; Animals; Anthracenes; Arginine; Benzylamines; DNA; Enteral Nutrition; Gene Silencing; Inflammation; Intestine, Small; Nitric Oxide Synthase Type II; Protein Binding; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Small Interfering; Transcription Factor AP-1

2011
Effect of donor JNK signal transduction inhibition on transplant outcome in brain dead rat model.
    Inflammation, 2012, Volume: 35, Issue:1

    Topics: Animals; Anthracenes; Brain Death; Graft Rejection; Graft Survival; JNK Mitogen-Activated Protein Kinases; Kidney Transplantation; MAP Kinase Signaling System; Rats; Rats, Inbred Lew; Reperfusion Injury

2012
Protective effects of SP600125 on renal ischemia-reperfusion injury in rats.
    The Journal of surgical research, 2011, Volume: 169, Issue:1

    Topics: Animals; Anthracenes; Apoptosis; Cytokines; Enzyme Inhibitors; Ischemia; Kidney; Male; MAP Kinase Kinase 4; Models, Animal; Phosphorylation; Rats; Rats, Inbred F344; Reactive Oxygen Species; Regional Blood Flow; Reperfusion Injury; Treatment Outcome

2011
[Protective effects and mechanism of SP600125 on lung ischemia/reperfusion injury in rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2012, Volume: 28, Issue:3

    Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Lung; MAP Kinase Signaling System; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reperfusion Injury

2012
The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways.
    Brain research, 2005, Feb-21, Volume: 1035, Issue:1

    Topics: Analysis of Variance; Animals; Anthracenes; Blotting, Western; Cell Count; Cell Death; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Immunoprecipitation; Ischemic Attack, Transient; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Neurons; Neuroprotective Agents; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Staining and Labeling; Time Factors

2005
Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2005, Volume: 25, Issue:6

    Topics: 14-3-3 Proteins; Animals; Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Brain Ischemia; Carrier Proteins; Cerebral Infarction; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Mice; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reperfusion Injury; Signal Transduction

2005
SP600125, a selective JNK inhibitor, aggravates hepatic ischemia-reperfusion injury.
    Experimental & molecular medicine, 2006, Aug-31, Volume: 38, Issue:4

    Topics: Animals; Anthracenes; Chemokines; Liver; Male; MAP Kinase Kinase 4; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Oxidative Stress; Reperfusion Injury

2006
SP600125, a selective JNK inhibitor, protects ischemic renal injury via suppressing the extrinsic pathways of apoptosis.
    Life sciences, 2007, May-08, Volume: 80, Issue:22

    Topics: Animals; Anthracenes; Apoptosis; Disease Models, Animal; JNK Mitogen-Activated Protein Kinases; Kidney; Kidney Diseases; Necrosis; Protective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction

2007
Stress-activated protein kinase inhibition to ameliorate lung ischemia reperfusion injury.
    The Journal of thoracic and cardiovascular surgery, 2008, Volume: 135, Issue:3

    Topics: Animals; Anthracenes; Blotting, Western; Bronchoalveolar Lavage Fluid; Butadienes; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Immunohistochemistry; Inflammation Mediators; Lung Diseases; Male; Mitogen-Activated Protein Kinases; Nitriles; Oxidative Stress; Peroxidase; Phosphorylation; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion Injury; Sensitivity and Specificity

2008