Page last updated: 2024-08-18

pyrazolanthrone and Inflammation

pyrazolanthrone has been researched along with Inflammation in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	10 (22.22)	29.6817
2010's	31 (68.89)	24.3611
2020's	4 (8.89)	2.80

Authors

Authors	Studies
Reddy, PA; Siddiqui, MA	1
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J	1
Gehringer, M; Koch, P; Laufer, SA	1
Chai, J; Jiang, S; Liu, Z; Zheng, R; Zhong, Z	1
Jiang, S; Tu, WJ; Wu, XL; Zhang, M; Zhang, Q; Zou, XY	1
Bai, B; Guo, L; Liang, G; Shan, X; Xiao, Z; Xu, F; Zhang, B; Zhang, Y; Zhao, Y; Zhu, X	1
Li, Y; Lin, W; Tang, M; Wang, X; Zhang, J; Zhang, K; Zhao, Y	1
Chang, L; Dai, M; Liu, A; Xu, G; Yang, J; Zheng, X	1
Cai, X; Han, X; Shen, H; Wang, Y; Wu, N; Zhang, H; Zhao, M; Zheng, Q	1
Jia, Y; Li, Y; Liu, X; Song, Y; Wang, J; Wu, H; Zhang, H; Zhou, S	1
Chen, Y; Geng, S; Jiang, Y; Li, X; Li, Y; Meng, Y; Wang, S; Wang, X; Wu, J; Xie, C; Yang, X; Zhong, C; Zhu, J; Zhu, W	1
Wang, J; Zhang, YL; Zhuang, N	1
Geng, C; Wei, J; Wu, C	1
Chosa, N; Ishisaki, A; Naruishi, K; Sawada, S; Takizawa, N	1
Anand, SS; Babu, PP; Maruthi, M	1
Anand, N; Hull, M; LaLone, V; Lee, E; Lee, T; Parameswaran, N	1
Liu, S; Liu, Z; Song, Y; Sun, G; Wang, C; Wang, F; Xi, S; Yan, L; Yan, N	1
Qian, W; Qian, Y; Sun, L; Wang, J; Xiao, H; Zhang, X; Zhao, J	1
Bennett, PR; Hagberg, H; Herbert, BR; Johnson, MR; Lee, YS; MacIntyre, DA; Migale, R; Peebles, D; Waddington, SN	1
Gong, S; Guo, Z; Shang, Y; Wang, Q; Wu, Q; Zhang, L	1
Cui, J; Hu, Y; Khachigian, LM; Li, D; Sun, L; Wang, M; Wong, J; Xie, J; Xue, J; Zhang, G; Zhang, S	1
Gao, R; Jiang, L; Liu, J; Liu, Y; Qian, W; Wang, J; Xiao, H; Zhou, J; Zhu, J	1
Chen, YC; Cheng, KT; Chien, CC; Shen, SC; Subbaraju, GV; Yang, LY	1
Chen, YC; Ji, H; Shao, JP; Wei, XN; Weng, GB; Ye, XL; Zhao, YR	1
Fang, L; Liu, RY; Shen, QY; Wu, HM	1
Bulut, G; Dönmez, YB; Erten, R; Kurdoglu, M; Kurdoglu, Z	1
Chen, G; Hu, Q; Jiang, S; Li, T; Mao, J; Nie, X; Wang, C; Wang, X; Xu, L; Yang, J; Zhang, Y	1
Chen, J; Gampa, A; Machado, RF; Sethuraman, S; Singla, S; Sysol, JR; Zhao, S	1
de Borst, MH; Hamming, I; Klok, PA; Kok, RJ; Navis, G; Prakash, J; Sandovici, M; van Goor, H	1
Bhargava, A; Cureton, EL; Curran, B; Ereso, AQ; Harken, AH; Liao, M; Poole, DP; Victorino, GP	1
Bala, M; Buechler, C; Kopp, A; Neumeier, M; Schäffler, A; Schölmerich, J	1
Ban, K; Kozar, RA; Santora, R	1
Fernaeus, SZ; Kaldmäe, M; Künnis-Beres, K; Land, T; Part, K; Svensson, C	1
Barateiro, A; Brites, D; Brito, MA; Falcão, AS; Fernandes, A; Silva, SL; Vaz, AR	1
Kennedy, A; Martinez, K; McIntosh, MK	1
He, SZ; Jian, CX; Li, CJ; Liu, XC; Liu, XF	1
Bhatt, KH; Chakraborty, R; Sodhi, A	1
Adcock, IM; Bennett, BL; Chung, KF; Eynott, PR; Leung, SY; Nath, P	1
Chen, JW; Chen, YH; Chen, YL; Hung, YY; Ku, HH; Lin, SJ; Shyue, SK; Tam, KB	1
Barger, SW; Wu, S	1
Calvert, JW; Yamaguchi, M; Yatsushige, H; Zhang, JH; Zhou, C	1
Bertelsen, M; Sanfridson, A	1
Doya, H; Fujitani, M; Hata, K; Ino, H; Moriya, H; Ohtori, S; Saito, T; Takahashi, K; Yamashita, T	1
Coimbra, TM; Costa, RS; Francescato, HD; Júnior, FB	1
Adcock, IM; Bennett, BL; Chung, KF; Ferguson, GD; Issa, R; Leung, SY; Nath, P; Williams, AS	1

Reviews

1 review(s) available for pyrazolanthrone and Inflammation

Article	Year
Inhibitors of c-Jun N-terminal kinases: an update. Journal of medicinal chemistry, 2015, Jan-08, Volume: 58, Issue:1 Topics: Central Nervous System Diseases; Humans; Inflammation; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Models, Molecular; Molecular Structure; Neoplasms; Protein Binding; Protein Kinase Inhibitors	2015

Other Studies

44 other study(ies) available for pyrazolanthrone and Inflammation

Article	Year
Small molecule JNK (c-Jun N-terminal kinase) inhibitors. Journal of medicinal chemistry, 2010, Apr-22, Volume: 53, Issue:8 Topics: Allosteric Regulation; Animals; Cardiovascular Diseases; Crystallography, X-Ray; Humans; Inflammation; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Metabolic Diseases; Neurodegenerative Diseases; Protein Conformation; Protein Kinase Inhibitors; Signal Transduction	2010
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. Current protocols in cytometry, 2010, Volume: Chapter 13 Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature	2010
miR-132-3p Modulates DUSP9-Dependent p38/JNK Signaling Pathways to Enhance Inflammation in the Amnion Leading to Labor. International journal of molecular sciences, 2022, Feb-07, Volume: 23, Issue:3 Topics: Amnion; Animals; Anthracenes; Cyclooxygenase 2; Dual-Specificity Phosphatases; Epithelial Cells; Female; Imidazoles; Inflammation; Labor, Obstetric; Male; MAP Kinase Signaling System; Mice; MicroRNAs; Pregnancy; Pyridines	2022
Osteocalcin reduces fat accumulation and inflammatory reaction by inhibiting ROS-JNK signal pathway in chicken embryonic hepatocytes. Poultry science, 2022, Volume: 101, Issue:11 Topics: Adenosine Triphosphate; Animals; Apoptosis; Chick Embryo; Chickens; Emulsions; Hepatocytes; Inflammation; Interleukin-1; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Osteocalcin; Reactive Oxygen Species; Signal Transduction; Tumor Necrosis Factor-alpha	2022
Inhibition Of JNK Phosphorylation By Curcumin Analog C66 Protects LPS-Induced Acute Lung Injury. Drug design, development and therapy, 2019, Volume: 13 Topics: Acute Lung Injury; Animals; Anthracenes; Cells, Cultured; Curcumin; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Injections, Intravenous; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Phosphorylation; Structure-Activity Relationship	2019
Inhibition of JNK ameliorates depressive-like behaviors and reduces the activation of pro-inflammatory cytokines and the phosphorylation of glucocorticoid receptors at serine 246 induced by neuroinflammation. Psychoneuroendocrinology, 2020, Volume: 113 Topics: Amygdala; Animals; Anthracenes; Brain; Cytokines; Depression; Hippocampus; Hypothalamo-Hypophyseal System; Inflammation; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Male; Phosphorylation; Pituitary-Adrenal System; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Serine	2020
Inhibition of inflammation by SP600125 in cholestatic liver injury is dependent on the administration‑based exposure profile. International journal of molecular medicine, 2020, Volume: 46, Issue:6 Topics: 1-Naphthylisothiocyanate; Animals; Anthracenes; Bile Acids and Salts; Biological Transport; Biomarkers; Cholestasis; Gene Expression Regulation; Inflammation; Liver; MAP Kinase Signaling System; Mice; RNA, Messenger	2020
JNK Inhibitor SP600125 Attenuates Paraquat-Induced Acute Lung Injury: an In Vivo and In Vitro Study. Inflammation, 2017, Volume: 40, Issue:4 Topics: A549 Cells; Acute Lung Injury; Animals; Anthracenes; Apoptosis; Enzyme Inhibitors; Humans; Inflammation; JNK Mitogen-Activated Protein Kinases; Oxidative Stress; Paraquat; Rats; Transcription Factor AP-1	2017
SP600125 suppresses Journal of molecular endocrinology, 2018, Volume: 60, Issue:2 Topics: Albuminuria; Animals; Anthracenes; Cell Nucleus; Diabetic Nephropathies; Fibrosis; Gene Deletion; Glucose; Inflammation; JNK Mitogen-Activated Protein Kinases; Kelch-Like ECH-Associated Protein 1; Kidney; Male; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Protein Transport; RNA, Small Interfering	2018
Curcumin suppresses JNK pathway to attenuate BPA-induced insulin resistance in LO2 cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97 Topics: Anthracenes; Benzhydryl Compounds; Cell Line; Curcumin; Enzyme Activation; Humans; Imidazoles; Inflammation; Insulin Resistance; MAP Kinase Signaling System; NF-kappa B; Oxidative Stress; Phenols; Pyridines; Pyrrolidines; Thiocarbamates	2018
[Salidroside inhibits inflammatory factor release in BV-2 cells through p38 and JNK pathways]. Sheng li xue bao : [Acta physiologica Sinica], 2018, Jun-25, Volume: 70, Issue:3 Topics: Animals; Anthracenes; Apoptosis; Cell Survival; Cells, Cultured; Glucosides; Imidazoles; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Microglia; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Pyridines; Tumor Necrosis Factor-alpha	2018
Mammalian STE20-like Kinase 1 Knockdown Attenuates TNFα-Mediated Neurodegenerative Disease by Repressing the JNK Pathway and Mitochondrial Stress. Neurochemical research, 2019, Volume: 44, Issue:7 Topics: Animals; Anthracenes; Apoptosis; Cell Line, Tumor; Cytochromes c; Dose-Response Relationship, Drug; Gene Knockdown Techniques; Inflammation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitochondria; Neurodegenerative Diseases; Oxidative Stress; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Tumor Necrosis Factor-alpha	2019
Secreted caveolin-1 enhances periodontal inflammation by targeting gingival fibroblasts. Biomedical research (Tokyo, Japan), 2013, Volume: 34, Issue:1 Topics: Anthracenes; Blotting, Western; Caveolin 1; Cell Survival; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gingiva; Humans; Inflammation; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 1; Matrix Metalloproteinase 10; Matrix Metalloproteinase 14; Periodontal Ligament; Periodontitis; Phosphorylation; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A	2013
The specific, reversible JNK inhibitor SP600125 improves survivability and attenuates neuronal cell death in experimental cerebral malaria (ECM). Parasitology research, 2013, Volume: 112, Issue:5 Topics: Animals; Anthracenes; Cell Death; Enzyme Inhibitors; Female; Humans; Inflammation; Malaria, Cerebral; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Neurons; Plasmodium berghei; Survival Analysis; Treatment Outcome	2013
Lithium chloride induces TNFα in mouse macrophages via MEK-ERK-dependent pathway. Journal of cellular biochemistry, 2014, Volume: 115, Issue:1 Topics: Animals; Anthracenes; Cell Line; Inflammation; Lithium Chloride; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; NF-kappa B; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 3; Tumor Necrosis Factor-alpha	2014
JNK and NADPH oxidase involved in fluoride-induced oxidative stress in BV-2 microglia cells. Mediators of inflammation, 2013, Volume: 2013 Topics: Acetophenones; Animals; Anthracenes; Antioxidants; Cell Line; Cell Survival; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fluorides; Gene Expression Regulation, Enzymologic; Inflammation; MAP Kinase Kinase 4; Melatonin; Mice; Microglia; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Oxygen; Phosphorylation; Reactive Oxygen Species	2013
Dexmedetomidine inhibits tumor necrosis factor-alpha and interleukin 6 in lipopolysaccharide-stimulated astrocytes by suppression of c-Jun N-terminal kinases. Inflammation, 2014, Volume: 37, Issue:3 Topics: Animals; Anthracenes; Anti-Inflammatory Agents; Astrocytes; Cell Survival; Cells, Cultured; Dexmedetomidine; Gene Expression; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha	2014
Activator protein 1 is a key terminal mediator of inflammation-induced preterm labor in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2014, Volume: 28, Issue:5 Topics: Animals; Anthracenes; Cytokines; Female; Inflammation; Labor, Obstetric; Lipopolysaccharides; Mice; Myometrium; NF-kappa B; NF-kappa B p50 Subunit; Obstetric Labor, Premature; Pregnancy; Pregnancy, Animal; Progesterone; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Progesterone; Time Factors; Toll-Like Receptor 4; Transcription Factor AP-1; Uterus	2014
Nuclear factor-κB as a link between endoplasmic reticulum stress and inflammation during cardiomyocyte hypoxia/reoxygenation. Cell biology international, 2014, Volume: 38, Issue:7 Topics: Animals; Anthracenes; Cell Hypoxia; Cells, Cultured; Cinnamates; eIF-2 Kinase; Endoplasmic Reticulum Stress; Endoribonucleases; Heart Rate; Heat-Shock Proteins; Inflammation; Multienzyme Complexes; Myocytes, Cardiac; NF-kappa B; Peptides; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Thiourea; Tumor Necrosis Factor-alpha; Tunicamycin	2014
Regulatory roles of c-jun in H5N1 influenza virus replication and host inflammation. Biochimica et biophysica acta, 2014, Volume: 1842, Issue:12 Pt A Topics: Animals; Anthracenes; Blotting, Western; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Cytokines; Dogs; Female; Gene Knockdown Techniques; Host-Pathogen Interactions; Humans; Inflammation; Influenza A Virus, H5N1 Subtype; Madin Darby Canine Kidney Cells; Mice, Inbred BALB C; Orthomyxoviridae Infections; Phosphorylation; Proto-Oncogene Proteins c-jun; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Virus Replication	2014
MAPK and NF-κB pathways are involved in bisphenol A-induced TNF-α and IL-6 production in BV2 microglial cells. Inflammation, 2015, Volume: 38, Issue:2 Topics: Animals; Anthracenes; Anti-Inflammatory Agents; Benzhydryl Compounds; Cell Line; Endocrine Disruptors; Enzyme Activation; Estradiol; Estrogen Receptor Antagonists; Estrogen Receptor Modulators; Estrogens; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fulvestrant; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Microglia; Neurodegenerative Diseases; NF-kappa B; Phenols; Tumor Necrosis Factor-alpha	2015
Hispolon inhibition of inflammatory apoptosis through reduction of iNOS/NO production via HO-1 induction in macrophages. Journal of ethnopharmacology, 2014, Oct-28, Volume: 156 Topics: Anthracenes; Apoptosis; Catechols; Dose-Response Relationship, Drug; Heme Oxygenase-1; Inflammation; Lipopolysaccharides; Macrophages; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nitriles; Reactive Oxygen Species; RNA, Small Interfering; Structure-Activity Relationship; Sulfones; Teichoic Acids; Transcription Factor AP-1	2014
IL-33-induced JNK pathway activation confers gastric cancer chemotherapy resistance. Oncology reports, 2015, Volume: 33, Issue:6 Topics: Anthracenes; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Inflammation; Interleukin-33; MAP Kinase Signaling System; Neoplasm Invasiveness; Stomach Neoplasms	2015
SP600125 promotes resolution of allergic airway inflammation via TLR9 in an OVA-induced murine acute asthma model. Molecular immunology, 2015, Volume: 67, Issue:2 Pt B Topics: Acute Disease; Animals; Anthracenes; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Cytokines; Disease Models, Animal; Female; Hypersensitivity; Immunoglobulin E; Inflammation; JNK Mitogen-Activated Protein Kinases; Lung; Mice, Inbred C57BL; Mucus; Ovalbumin; Phosphorylation; Toll-Like Receptor 9	2015
Effects of jnk inhibitor on inflammation and fibrosis in the ovary tissue of a rat model of polycystic ovary syndrome. International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:8 Topics: Animals; Anthracenes; Disease Models, Animal; Female; Fibrosis; Immunohistochemistry; Inflammation; MAP Kinase Kinase 4; Polycystic Ovary Syndrome; Protein Kinase Inhibitors; Rats; Rats, Wistar	2015
Arsenic trioxide mediates HAPI microglia inflammatory response and subsequent neuron apoptosis through p38/JNK MAPK/STAT3 pathway. Toxicology and applied pharmacology, 2016, 07-15, Volume: 303 Topics: Animals; Anthracenes; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line; Cell Line, Tumor; Humans; Imidazoles; Inflammation; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Microglia; Neurons; Oxides; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Rats; Signal Transduction; STAT3 Transcription Factor	2016
Loss of lung WWOX expression causes neutrophilic inflammation. American journal of physiology. Lung cellular and molecular physiology, 2017, 06-01, Volume: 312, Issue:6 Topics: A549 Cells; Animals; Anthracenes; Cell Nucleus; Chemotaxis; Cytokines; Gene Knockdown Techniques; Gene Silencing; Inflammation; Inflammation Mediators; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Lung; Male; Mice, Inbred C57BL; Neutrophils; NF-kappa B; Oxidoreductases; Protein Binding; Protein Transport; Pulmonary Alveoli; Transcription Factor AP-1; Tumor Suppressor Proteins; WW Domain-Containing Oxidoreductase	2017
c-Jun NH2-terminal kinase is crucially involved in renal tubulo-interstitial inflammation. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:3 Topics: Adolescent; Adult; Animals; Anthracenes; Blotting, Western; Cell Line; Chemokine CCL2; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Female; Gene Expression; Humans; Immunohistochemistry; Inflammation; JNK Mitogen-Activated Protein Kinases; Kidney Diseases; Kidney Tubules; Macrophages; Male; Middle Aged; Nephritis, Interstitial; Protein Kinase Inhibitors; Rats; Rats, Wistar; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Young Adult	2009
Local secretion of urocortin 1 promotes microvascular permeability during lipopolysaccharide-induced inflammation. Endocrinology, 2009, Volume: 150, Issue:12 Topics: Aniline Compounds; Animals; Anthracenes; Capillary Permeability; Drug Synergism; Female; Fluorescent Antibody Technique; Gene Expression; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Mesentery; Platelet Endothelial Cell Adhesion Molecule-1; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Tumor Necrosis Factor-alpha; Urocortins	2009
Toll-like receptor ligands cause proinflammatory and prodiabetic activation of adipocytes via phosphorylation of extracellular signal-regulated kinase and c-Jun N-terminal kinase but not interferon regulatory factor-3. Endocrinology, 2010, Volume: 151, Issue:3 Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Adult; Animals; Anthracenes; Butadienes; Chemokine CCL2; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Inflammation; Insulin; Interferon Regulatory Factor-3; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mice; Myeloid Differentiation Factor 88; Nitriles; Phosphorylation; RNA, Messenger; Toll-Like Receptors	2010
Enteral arginine modulates inhibition of AP-1/c-Jun by SP600125 in the postischemic gut. Molecular and cellular biochemistry, 2011, Volume: 347, Issue:1-2 Topics: Amidines; Animals; Anthracenes; Arginine; Benzylamines; DNA; Enteral Nutrition; Gene Silencing; Inflammation; Intestine, Small; Nitric Oxide Synthase Type II; Protein Binding; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Small Interfering; Transcription Factor AP-1	2011
Pro-survival effects of JNK and p38 MAPK pathways in LPS-induced activation of BV-2 cells. Biochemical and biophysical research communications, 2011, Mar-18, Volume: 406, Issue:3 Topics: Animals; Anthracenes; Apoptosis; Cell Line; Cell Survival; Inflammation; Lipopolysaccharides; MAP Kinase Kinase 4; Mice; Microglia; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors	2011
Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin. Experimental neurology, 2011, Volume: 229, Issue:2 Topics: Analysis of Variance; Animals; Anthracenes; Bilirubin; Blotting, Western; Caspases; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Inflammation; Interleukin-1beta; MAP Kinase Kinase 4; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha	2011
JNK inhibition by SP600125 attenuates trans-10, cis-12 conjugated linoleic acid-mediated regulation of inflammatory and lipogenic gene expression. Lipids, 2011, Volume: 46, Issue:10 Topics: Activating Transcription Factor 3; Adipocytes; Adult; Anthracenes; Cells, Cultured; Female; Gene Expression Regulation; Humans; Inflammation; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Linoleic Acids, Conjugated; Lipogenesis; Middle Aged; Signal Transduction; Young Adult	2011
IL-33 is induced by amyloid-β stimulation and regulates inflammatory cytokine production in retinal pigment epithelium cells. Inflammation, 2012, Volume: 35, Issue:2 Topics: Amyloid beta-Peptides; Anthracenes; Butadienes; Cell Line; Humans; Imidazoles; Inflammation; Interleukin-1 Receptor-Like 1 Protein; Interleukin-1beta; Interleukin-33; Interleukin-6; Interleukin-8; Interleukins; JNK Mitogen-Activated Protein Kinases; Macular Degeneration; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Nitriles; Peptide Fragments; Pyridines; Receptors, Cell Surface; Retinal Pigment Epithelium; Sulfones; Tumor Necrosis Factor-alpha	2012
Peptidoglycan induced expression of peroxisome proliferator-activated receptor γ in mouse peritoneal macrophages: role of ERK and JNK MAP kinases. Cytokine, 2012, Volume: 60, Issue:3 Topics: Animals; Anthracenes; Cells, Cultured; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation; Inflammation; Interleukin-12 Subunit p40; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Macrophages, Peritoneal; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; NF-kappa B; Peptidoglycan; PPAR gamma; RNA Interference; RNA, Small Interfering; Toll-Like Receptor 2; Transcription Factor RelA; Tumor Necrosis Factor-alpha	2012
Allergen-induced inflammation and airway epithelial and smooth muscle cell proliferation: role of Jun N-terminal kinase. British journal of pharmacology, 2003, Volume: 140, Issue:8 Topics: Actins; Animals; Anthracenes; Bronchi; Bronchoalveolar Lavage Fluid; Cell Count; Cell Division; Chronic Disease; Eosinophils; Hypersensitivity; Immunohistochemistry; Inflammation; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Myocytes, Smooth Muscle; Ovalbumin; Rats; Rats, Inbred BN; Respiratory Mucosa	2003
Superoxide dismutase inhibits the expression of vascular cell adhesion molecule-1 and intracellular cell adhesion molecule-1 induced by tumor necrosis factor-alpha in human endothelial cells through the JNK/p38 pathways. Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:2 Topics: Anthracenes; Aorta; Arteriosclerosis; Cell Adhesion; Depression, Chemical; Endothelial Cells; Endothelium, Vascular; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Inflammation; Intercellular Adhesion Molecule-1; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; NADPH Oxidases; Neutrophils; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Recombinant Fusion Proteins; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Transcription Factor AP-1; Transcription, Genetic; Transduction, Genetic; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	2005
Induction of serine racemase by inflammatory stimuli is dependent on AP-1. Annals of the New York Academy of Sciences, 2004, Volume: 1035 Topics: Amino Acid Isomerases; Animals; Anthracenes; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Cloning, Molecular; Dexamethasone; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Gene Expression Regulation; Humans; Inflammation; Lipopolysaccharides; Luciferases; Mice; Microglia; Mutagenesis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Transcription Factor AP-1; Transfection	2004
Role of c-Jun N-terminal kinase in cerebral vasospasm after experimental subarachnoid hemorrhage. Stroke, 2005, Volume: 36, Issue:7 Topics: Angiography; Animals; Anthracenes; Blotting, Western; Cytokines; Dimethyl Sulfoxide; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemorrhage; Immunohistochemistry; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Leukocytes; Phosphorylation; Signal Transduction; Subarachnoid Hemorrhage; Time Factors; Tumor Necrosis Factor-alpha; Vasospasm, Intracranial	2005
Inflammatory pathway analysis using a high content screening platform. Assay and drug development technologies, 2005, Volume: 3, Issue:3 Topics: Anthracenes; Cell Line, Tumor; Cell Nucleus; Cytosol; Enzyme Inhibitors; Fluorescence; Fluorescent Antibody Technique; HeLa Cells; Humans; Imidazoles; Immunoblotting; Inflammation; Interleukin-1; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reproducibility of Results; RNA, Small Interfering; Signal Transduction; Technology, Pharmaceutical; Transcription Factor RelA; Transfection	2005
c-Jun N-terminal kinase activation in dorsal root ganglion contributes to pain hypersensitivity. Biochemical and biophysical research communications, 2005, Sep-16, Volume: 335, Issue:1 Topics: Animals; Anthracenes; Enzyme Activation; Ganglia, Spinal; Hyperalgesia; Inflammation; JNK Mitogen-Activated Protein Kinases; Male; Nerve Growth Factor; Neurons; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Temperature	2005
Effect of JNK inhibition on cisplatin-induced renal damage. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:8 Topics: Animals; Anthracenes; Apoptosis; Cisplatin; Glomerular Filtration Rate; Inflammation; Kidney; Kidney Diseases; Lipid Peroxidation; Male; MAP Kinase Kinase 4; Necrosis; Protein Kinase Inhibitors; Rats; Rats, Wistar	2007
Attenuation of ozone-induced airway inflammation and hyper-responsiveness by c-Jun NH2 terminal kinase inhibitor SP600125. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:1 Topics: Animals; Anthracenes; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Gene Expression Regulation; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lung; Male; Mice; Mice, Inbred BALB C; Oligonucleotide Array Sequence Analysis; Ozone; Phosphorylation; Polymerase Chain Reaction; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun	2007