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pyrazolanthrone and Degenerative Diseases, Central Nervous System

pyrazolanthrone has been researched along with Degenerative Diseases, Central Nervous System in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Reddy, PA; Siddiqui, MA1
Ahmad, R; Ahmad, S; Ikram, M; Khan, A; Khan, MS; Kim, MO; Rehman, IUR1
Cao, H; Chen, Z; Chi, S; Guo, S; Hu, Q; Sun, T; Tao, H; Yang, J; Zhang, L; Zhu, H1
Geng, C; Wei, J; Wu, C1
Fan, Z; Li, P; Mei, C; Wang, X; Zhang, M; Zhao, C1
Gao, R; Jiang, L; Liu, J; Liu, Y; Qian, W; Wang, J; Xiao, H; Zhou, J; Zhu, J1
Davies, C; Tournier, C1

Reviews

1 review(s) available for pyrazolanthrone and Degenerative Diseases, Central Nervous System

ArticleYear
Exploring the function of the JNK (c-Jun N-terminal kinase) signalling pathway in physiological and pathological processes to design novel therapeutic strategies.
    Biochemical Society transactions, 2012, Volume: 40, Issue:1

    Topics: Animals; Anthracenes; Apoptosis; Brain; Enzyme Activation; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Neoplasms; Neurodegenerative Diseases

2012

Other Studies

6 other study(ies) available for pyrazolanthrone and Degenerative Diseases, Central Nervous System

ArticleYear
Small molecule JNK (c-Jun N-terminal kinase) inhibitors.
    Journal of medicinal chemistry, 2010, Apr-22, Volume: 53, Issue:8

    Topics: Allosteric Regulation; Animals; Cardiovascular Diseases; Crystallography, X-Ray; Humans; Inflammation; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Metabolic Diseases; Neurodegenerative Diseases; Protein Conformation; Protein Kinase Inhibitors; Signal Transduction

2010
Inhibition of JNK Alleviates Chronic Hypoperfusion-Related Ischemia Induces Oxidative Stress and Brain Degeneration via Nrf2/HO-1 and NF-
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Aging; Animals; Anthracenes; Apoptosis; Brain Ischemia; Heme Oxygenase-1; Hippocampus; JNK Mitogen-Activated Protein Kinases; Male; Memory Disorders; Mice, Inbred C57BL; Models, Biological; Neurodegenerative Diseases; Neurons; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Perfusion; Phosphorylation; Signal Transduction; Synapses; Up-Regulation

2020
Small molecular compounds efficiently convert human fibroblasts directly into neurons.
    Molecular medicine reports, 2020, Volume: 22, Issue:6

    Topics: Amides; Anthracenes; Cell Differentiation; Cells, Cultured; Cellular Reprogramming; Cellular Reprogramming Techniques; Colforsin; Culture Media, Conditioned; Fibroblasts; Foreskin; Humans; Indoles; Male; Maleimides; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Pyrazoles; Pyridines; Pyrimidines; Transcription Factors

2020
Mammalian STE20-like Kinase 1 Knockdown Attenuates TNFα-Mediated Neurodegenerative Disease by Repressing the JNK Pathway and Mitochondrial Stress.
    Neurochemical research, 2019, Volume: 44, Issue:7

    Topics: Animals; Anthracenes; Apoptosis; Cell Line, Tumor; Cytochromes c; Dose-Response Relationship, Drug; Gene Knockdown Techniques; Inflammation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitochondria; Neurodegenerative Diseases; Oxidative Stress; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Tumor Necrosis Factor-alpha

2019
MAPK Pathway Inhibitors Attenuated Hydrogen Peroxide Induced Damage in Neural Cells.
    BioMed research international, 2019, Volume: 2019

    Topics: Animals; Anthracenes; Butadienes; Cell Survival; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Imidazoles; Mice; Mitogen-Activated Protein Kinase Kinases; Neurodegenerative Diseases; Neurons; Nitriles; Oxidative Stress; PC12 Cells; Primary Cell Culture; Pyridines; Rats; Reactive Oxygen Species

2019
MAPK and NF-κB pathways are involved in bisphenol A-induced TNF-α and IL-6 production in BV2 microglial cells.
    Inflammation, 2015, Volume: 38, Issue:2

    Topics: Animals; Anthracenes; Anti-Inflammatory Agents; Benzhydryl Compounds; Cell Line; Endocrine Disruptors; Enzyme Activation; Estradiol; Estrogen Receptor Antagonists; Estrogen Receptor Modulators; Estrogens; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fulvestrant; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Microglia; Neurodegenerative Diseases; NF-kappa B; Phenols; Tumor Necrosis Factor-alpha

2015