pyrazolanthrone has been researched along with Breast Neoplasms in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (52.63) | 29.6817 |
| 2010's | 8 (42.11) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Y; Wang, C; Wang, E; Zhang, D; Zhao, N; Zheng, Q | 1 |
| Barbour, MJ; Cunningham, MR; Gould, GW; Plevin, RJ; Wood, RA | 1 |
| Phelan, S; Taparra, K; Tehan, L | 1 |
| André, F; Bianchini, G; Bottai, G; de Thè, H; Desmedt, C; Di Leo, A; Győrffy, B; Hortobagyi, GN; Iwamoto, T; Kéri, G; Lehmann-Che, J; Orfi, L; Pusztai, L; Santarpia, L; Sotiriou, C; Turner, NC | 1 |
| Bedalov, CO; Prosperi, JR; Soto, KF; VanKlompenberg, MK | 1 |
| Agboke, FA; Cunliffe, HE; Fan, P; Jordan, VC; Maximov, PY; McDaniel, RE; Ramos, P; Russell, ML; Zou, X | 1 |
| Cui, W; Hu, JL; Jin, Y; Xiao, L | 1 |
| Colburn, NH; Han, X; Matt, Y; Shu, Y; Sun, Y; Wang, S; Yin, Y | 1 |
| Kang, HS; Kim, HS; Kim, JH; Kim, TH; Ro, J; Yoon, S | 1 |
| Camp, JT; Kimple, RJ; Sambade, MJ; Sartor, CI; Shields, JM | 1 |
| Kline, K; Sanders, BG; Tiwary, R; Yu, W | 1 |
| Bae, SY; Cho, DH; Choe, JH; Choi, MY; Han, J; Kim, JH; Kim, JS; Kim, S; Koo, M; Lee, JE; Lee, SK; Nam, SJ; Yang, JH | 1 |
| Deng, Z; Du, WW; Fang, L; Jeyapalan, Z; Seth, A; Shan, SW; Yang, BB; Yang, BL; Yee, AJ; Zhang, Y | 1 |
| Koller, E; Marietta, PM; Mingo-Sion, AM; Van Den Berg, CL; Wolf, DM | 1 |
| Casero, RA; Davidson, NE; Frydman, B; Hacker, A; Hager, E; Huang, Y; Keen, JC; Marton, LJ; Reddy, VK; Smith, R; Valasinas, AL | 1 |
| Faller, DV; Wang, S; Zhang, B | 1 |
| Huang, L; Li, F; Lu, Y; Ma, D; Meng, L; Wang, S; Xing, H; Xu, G; Zhou, J; Zhu, H | 1 |
| Jung, M; Lee, SA | 1 |
| Chen, YC; Lin, CW; Shen, SC; Yang, LY | 1 |
19 other study(ies) available for pyrazolanthrone and Breast Neoplasms
| Article | Year |
|---|---|
BHLHE41 suppresses MCF-7 cell invasion via MAPK/JNK pathway.
Topics: Anthracenes; Basic Helix-Loop-Helix Transcription Factors; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; MAP Kinase Kinase 4; MCF-7 Cells; Mitogen-Activated Protein Kinase Kinases; Neoplasm Invasiveness; Neoplasm Proteins; Signal Transduction; Transcriptional Activation | 2020 |
Conflicting evidence for the role of JNK as a target in breast cancer cell proliferation: Comparisons between pharmacological inhibition and selective shRNA knockdown approaches.
Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Female; Gene Knockdown Techniques; Humans; Isoenzymes; Janus Kinase Inhibitors; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; MCF-7 Cells; Molecular Targeted Therapy; Phosphorylation; RNA, Small Interfering | 2018 |
Peroxiredoxin overexpression in MCF-7 breast cancer cells and regulation by cell proliferation and oxidative stress.
Topics: Acetylcysteine; Anthracenes; Antioxidants; Breast Neoplasms; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; MCF-7 Cells; Oxidative Stress; Peroxiredoxins; Reactive Oxygen Species; RNA, Messenger; Up-Regulation | 2013 |
TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers.
Topics: Anthracenes; Breast; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Female; Genes, p53; Humans; Mutation; Neoplasm Recurrence, Local; Prognosis; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Survival Analysis; Tumor Suppressor Protein p53 | 2014 |
APC selectively mediates response to chemotherapeutic agents in breast cancer.
Topics: Adenomatous Polyposis Coli Protein; Animals; Anthracenes; Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase 4; Mice; Mice, Transgenic; Paclitaxel; Pyrimidines; src-Family Kinases | 2015 |
Integration of Downstream Signals of Insulin-like Growth Factor-1 Receptor by Endoplasmic Reticulum Stress for Estrogen-Induced Growth or Apoptosis in Breast Cancer Cells.
Topics: Anthracenes; Apoptosis; Breast Neoplasms; Cell Growth Processes; Endoplasmic Reticulum Stress; Estrogens; Female; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; MCF-7 Cells; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1 | 2015 |
[Impact of PTEN gene knockout in human breast carcinoma MCF-7 cells on activity of JNK pathway].
Topics: Activating Transcription Factor 2; Anthracenes; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Female; Gene Knockout Techniques; Humans; JNK Mitogen-Activated Protein Kinases; Oligonucleotides, Antisense; Phosphorylation; Proto-Oncogene Proteins c-jun; PTEN Phosphohydrolase; Signal Transduction; Transfection | 2008 |
JNK/AP-1 pathway is involved in tumor necrosis factor-alpha induced expression of vascular endothelial growth factor in MCF7 cells.
Topics: Anthracenes; Breast Neoplasms; Cell Line, Tumor; Chromatin Immunoprecipitation; Female; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Phosphorylation; RNA, Messenger; Signal Transduction; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2009 |
SP600125, an inhibitor of Jnk pathway, reduces viability of relatively resistant cancer cells to doxorubicin.
Topics: Animals; Anthracenes; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 8; Protein Kinase Inhibitors; RNA, Small Interfering; Stomach Neoplasms | 2009 |
Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK.
Topics: Anthracenes; Breast Neoplasms; Cell Line, Tumor; Enzyme Activation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Lapatinib; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinase Kinases; Proto-Oncogene Proteins c-raf; Quinazolines; Radiation Tolerance; Receptor, ErbB-2; Tumor Cells, Cultured | 2009 |
α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways.
Topics: 1-Phosphatidylinositol 4-Kinase; alpha-Tocopherol; Androstadienes; Anthracenes; Antioxidants; Apoptosis; Blotting, Western; Breast Neoplasms; Butadienes; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Immunosuppressive Agents; Insulin Receptor Substrate Proteins; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Nitriles; Phosphorylation; RNA, Small Interfering; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Wortmannin | 2011 |
Smad7 acts as a negative regulator of the epidermal growth factor (EGF) signaling pathway in breast cancer cells.
Topics: Anthracenes; Breast Neoplasms; Butadienes; Cell Line, Tumor; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Matrix Metalloproteinase 9; Nitriles; Phosphorylation; RNA, Messenger; Signal Transduction; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta1 | 2012 |
Versican G3 domain modulates breast cancer cell apoptosis: a mechanism for breast cancer cell response to chemotherapy and EGFR therapy.
Topics: Animals; Anthracenes; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Survival; Docetaxel; Doxorubicin; Epirubicin; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Green Fluorescent Proteins; Humans; Mice; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sphingosine; Taxoids; Tyrphostins; Versicans | 2011 |
Inhibition of JNK reduces G2/M transit independent of p53, leading to endoreduplication, decreased proliferation, and apoptosis in breast cancer cells.
Topics: Anthracenes; Apoptosis; Breast Neoplasms; Cell Division; Cell Line, Tumor; DNA Replication; Doxorubicin; G2 Phase; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Mitosis; Oligonucleotides, Antisense; Paclitaxel; Tumor Suppressor Protein p53; Ultraviolet Rays | 2004 |
Regulation of polyamine analogue cytotoxicity by c-Jun in human MDA-MB-435 cancer cells.
Topics: Anthracenes; Apoptosis; Breast Neoplasms; Cell Division; Gene Expression Regulation, Neoplastic; Humans; Mutation; Peptide Fragments; Phosphorylation; Polyamines; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Transfection; Tumor Cells, Cultured; Up-Regulation | 2004 |
BRG1/BRM and prohibitin are required for growth suppression by estrogen antagonists.
Topics: Anthracenes; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin; Chromatin Immunoprecipitation; DNA Helicases; Enzyme Inhibitors; Estrogen Antagonists; Female; Flow Cytometry; G1 Phase; Gene Expression Regulation; Humans; Immunoblotting; Luciferases; Mitogen-Activated Protein Kinase 8; Nuclear Proteins; Precipitin Tests; Prohibitins; Receptors, Estrogen; Repressor Proteins; RNA, Small Interfering; Tamoxifen; Transcription Factors | 2004 |
Essential role of c-Jun-NH2-terminal kinase on synergy induction of apoptosis by TRAIL plus ADM in ADM resistant MCF-7/ADM cells.
Topics: Anthracenes; Antibiotics, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Caspase 8; Caspase 9; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Female; Flow Cytometry; Humans; JNK Mitogen-Activated Protein Kinases; Membrane Glycoproteins; Mitochondria; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2006 |
The nucleoside analog sangivamycin induces apoptotic cell death in breast carcinoma MCF7/adriamycin-resistant cells via protein kinase Cdelta and JNK activation.
Topics: Anthracenes; Antibiotics, Antineoplastic; Apoptosis; Breast Neoplasms; Caspases; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Humans; JNK Mitogen-Activated Protein Kinases; Lamin Type A; MAP Kinase Kinase 4; Neoplasm Proteins; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Kinase C-delta; Protein Processing, Post-Translational; Pyrimidine Nucleosides | 2007 |
IGF-I plus E2 induces proliferation via activation of ROS-dependent ERKs and JNKs in human breast carcinoma cells.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Anthracenes; Antineoplastic Agents; Antioxidants; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Estradiol; Extracellular Signal-Regulated MAP Kinases; Female; Flavanones; Flavonoids; Glycosides; Humans; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinases; Molecular Structure; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Quercetin; Reactive Oxygen Species; Signal Transduction; Structure-Activity Relationship; Transfection | 2007 |