pyrazinoic acid has been researched along with Tuberculosis, Drug-Resistant in 5 studies
pyrazinoic acid: active metabolite of pyrazinamide; structure
pyrazine-2-carboxylic acid : The parent compound of the class of pyrazinecarboxylic acids, that is pyrazine bearing a single carboxy substituent. The active metabolite of the antitubercular drug pyrazinamide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Nonlinear mixed-effects modelling using Monolix 2018R1 software was employed to estimate population pharmacokinetic parameters." | 1.51 | Population Pharmacokinetic Modelling of Pyrazinamide and Pyrazinoic Acid in Patients with Multi-Drug Resistant Tuberculosis. ( Mugabo, P; Mulubwa, M, 2019) |
| "Pyrazinamide (PZA) is a critical component of current first-line TB therapy." | 1.48 | Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis. ( Braunstein, M; Durham, PG; Hayden, JD; Hickey, AJ; Lin, FC; Miller, BK; Montgomery, SA; Rank, L; Welch, JT; Young, EF; Zulauf, KE, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, Y | 1 |
| Xu, Y | 1 |
| Guo, C | 1 |
| Xue, X | 1 |
| Lin, D | 1 |
| Lin, K | 1 |
| Montgomery, SA | 1 |
| Young, EF | 2 |
| Durham, PG | 2 |
| Zulauf, KE | 1 |
| Rank, L | 1 |
| Miller, BK | 1 |
| Hayden, JD | 2 |
| Lin, FC | 1 |
| Welch, JT | 2 |
| Hickey, AJ | 2 |
| Braunstein, M | 1 |
| Mugabo, P | 1 |
| Mulubwa, M | 1 |
| Perkowski, E | 1 |
| Malik, S | 1 |
| Zhong, L | 1 |
| Braunstein, MS | 1 |
| Kim, HJ | 1 |
| Kwak, HK | 1 |
| Lee, J | 1 |
| Yun, YJ | 1 |
| Lee, JS | 1 |
| Lee, MS | 1 |
| Min, SY | 1 |
| Park, SK | 1 |
| Kang, HS | 1 |
| Maeng, YH | 1 |
| Kim, SY | 2 |
| Kook, YH | 1 |
| Kim, YR | 1 |
| Lee, KH | 1 |
5 other studies available for pyrazinoic acid and Tuberculosis, Drug-Resistant
| Article | Year |
|---|---|
Discovery and evaluation of new compounds targeting ribosomal protein S1 in antibiotic-resistant Mycobacterium Tuberculosis.
Topics: Acetamides; Anti-Bacterial Agents; Drug Discovery; Hypoxanthine; Microbial Sensitivity Tests; Molecu | 2020 |
Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis.
Topics: Aerosols; Animals; Antitubercular Agents; Bacterial Load; Disease Models, Animal; Drug Therapy, Comb | 2018 |
Population Pharmacokinetic Modelling of Pyrazinamide and Pyrazinoic Acid in Patients with Multi-Drug Resistant Tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Chromatography, Liquid; Female; Humans; Male; Middle Aged; | 2019 |
Inhaled Pyrazinoic Acid Esters for the Treatment of Tuberculosis.
Topics: Administration, Inhalation; Aerosols; Animals; Antitubercular Agents; Esters; Guinea Pigs; Male; Mic | 2016 |
Patterns of pncA mutations in drug-resistant Mycobacterium tuberculosis isolated from patients in South Korea.
Topics: Adult; Amidohydrolases; Antitubercular Agents; Bacterial Proteins; Base Sequence; DNA Mutational Ana | 2012 |