pyrazines has been researched along with Pulmonary Fibrosis in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Huan, X; Wang, K; Wang, L; Wang, X; Zhang, Y; Zu, C | 1 |
| Hao, L; Huang, YQ; Liu, MW; Su, MX; Tang, DY; Xun, XH | 1 |
| Cai, X; Chen, P; Chen, Z; Ge, J; Hu, H; Li, K; Pan, X; Xia, L; Yang, Y; Yu, K; Zhang, J; Zhuang, J | 1 |
| Abe, S; Hino, T; Hosokawa, T; Inage, M; Kato, S; Nakamura, H; Ogura, M; Saito, H; Sata, M; Takabatake, N; Terashita, K; Tomoike, H | 1 |
| Budinger, GR; Jain, M; Mutlu, GM; Weiss, CH | 1 |
| Budinger, GR; Chandel, NS; Chiarella, SE; Ghosh, AK; Go, LH; Jain, M; Kamp, DW; Lam, AP; Mutlu, GM; Pardo, A; Rivera, S; Selman, M; Sznajder, JI; Urich, D; Varga, J; Wu, M; Zirk, A | 1 |
| Cagnon, L; Duboux, G; Fioraso-Cartier, L; Gaggini, F; Gradia, A; Heitz, F; Houngninou-Molango, S; Laleu, B; Merlot, C; Orchard, M; Page, P; Szyndralewiez, C | 1 |
| Li, MY; Matsumoto, K; Mizuno, S; Nakamura, T | 1 |
| Du, HK; Gao, XX; Li, HW; Wang, YF | 1 |
| Berrebi, A; Duek, A; Feldberg, E; Haran, M | 1 |
| Fujita, M; Harada, E; Ikegame, S; Inoshima, I; Kuwano, K; Nakanishi, Y; Ouchi, H; Ye, Q | 1 |
| Argiroffo, CB; Bongiovanni, M; Chizzolini, C; Dayer, JM; Djaafar, S; Donati, Y; Ferrari-Lacraz, S; Fineschi, S; Goffin, L; Naso, F; Pache, JC | 1 |
| Cai, H; Dai, L; Hou, J | 1 |
| Cai, H; Dai, L; Hou, J; Huang, M | 1 |
| Chen, XY | 1 |
| Bogarelli, D; Ferliga, G; Paroli, M | 1 |
1 review(s) available for pyrazines and Pulmonary Fibrosis
| Article | Year |
|---|---|
Proteasomal regulation of pulmonary fibrosis.
Topics: Animals; Boronic Acids; Bortezomib; Clinical Trials as Topic; Humans; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pulmonary Fibrosis; Pyrazines; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1; Ubiquitin | 2010 |
15 other study(ies) available for pyrazines and Pulmonary Fibrosis
| Article | Year |
|---|---|
Blocking TG2 attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting EMT.
Topics: Acetates; Actins; Animals; Antibiotics, Antineoplastic; Benzopyrans; Bleomycin; Cadherins; Cell Line; Epithelial Cells; Epithelial-Mesenchymal Transition; Gene Knockdown Techniques; GTP-Binding Proteins; In Vitro Techniques; Mice; Protein Glutamine gamma Glutamyltransferase 2; Pulmonary Fibrosis; Pyrazines; Respiratory Mucosa; Transglutaminases; Vimentin | 2020 |
Ligustrazin increases lung cell autophagy and ameliorates paraquat-induced pulmonary fibrosis by inhibiting PI3K/Akt/mTOR and hedgehog signalling via increasing miR-193a expression.
Topics: A549 Cells; Animals; Autophagy; Collagen Type I; Female; Humans; Mice; MicroRNAs; Oxidative Stress; Paraquat; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pulmonary Fibrosis; Pyrazines; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases; Transforming Growth Factor beta1 | 2019 |
Inhibition of angiogenesis, fibrosis and thrombosis by tetramethylpyrazine: mechanisms contributing to the SDF-1/CXCR4 axis.
Topics: Angiogenesis Inhibitors; Animals; Cell Line; Cell Movement; Chemokine CXCL12; Cornea; Humans; Lung; Male; Neovascularization, Pathologic; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Fibrosis; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, CXCR4; Signal Transduction; Thrombosis | 2014 |
Vesnarinone represses the fibrotic changes in murine lung injury induced by bleomycin.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cytokines; Diet; Hyaluronic Acid; Hydroxyproline; Lung; Male; Mice; Mice, Inbred ICR; Pulmonary Fibrosis; Pyrazines; Quinolines; Receptors, Tumor Necrosis Factor; Severity of Illness Index | 2009 |
Proteasomal inhibition after injury prevents fibrosis by modulating TGF-β(1) signalling.
Topics: Animals; Autocrine Communication; Bleomycin; Boronic Acids; Bortezomib; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; PPAR gamma; Proteasome Inhibitors; Pulmonary Fibrosis; Pyrazines; Scleroderma, Systemic; Signal Transduction; Skin; Transforming Growth Factor beta1 | 2012 |
Design, synthesis and biological activity of original pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives as novel dual Nox4/Nox1 inhibitors.
Topics: Administration, Oral; Animals; Azepines; Bleomycin; Disease Models, Animal; Enzyme Inhibitors; Humans; Male; Mice; Mice, Inbred C57BL; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Oxazines; Pulmonary Fibrosis; Pyrazines; Pyridones; Structure-Activity Relationship | 2011 |
HGF reduces advancing lung fibrosis in mice: a potential role for MMP-dependent myofibroblast apoptosis.
Topics: Actins; Animals; Apoptosis; Bleomycin; Cell Line; Enzyme Inhibitors; Fibroblasts; Fibronectins; Hepatocyte Growth Factor; Humans; Hydroxamic Acids; Lung; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Muscle Cells; Proto-Oncogene Proteins c-met; Pulmonary Fibrosis; Pyrazines; Recombinant Proteins; Signal Transduction; Sulfonamides; Tissue Distribution | 2005 |
[Effect of Ligustrazine on type I, III collagen synthesis in lung tissue of silica-treated rat].
Topics: Animals; Collagen Type I; Collagen Type III; Female; Lung; Male; Pulmonary Fibrosis; Pyrazines; Random Allocation; Rats; Rats, Wistar; Silicon Dioxide | 2006 |
Pulmonary fibrosis in a myeloma patient on bortezomib treatment. A new severe adverse effect of a new drug.
Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Fatal Outcome; Female; Humans; Middle Aged; Multiple Myeloma; Pulmonary Fibrosis; Pyrazines; Recurrence; Respiratory Insufficiency; Steroids; Treatment Failure | 2007 |
The role of collagenases in experimental pulmonary fibrosis.
Topics: Administration, Oral; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagenases; Gelatin; Hydroxamic Acids; Hydroxyproline; Immunoblotting; Male; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred ICR; Protease Inhibitors; Pulmonary Fibrosis; Pyrazines; Sulfonamides | 2008 |
In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis.
Topics: Animals; Bleomycin; Boronic Acids; Bortezomib; Cells, Cultured; Collagen Type I; Fibrosis; Hydroxyproline; Leupeptins; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proteasome Inhibitors; Protein Serine-Threonine Kinases; Pulmonary Fibrosis; Pyrazines; Scleroderma, Systemic; Signal Transduction; Skin; Transforming Growth Factor beta | 2008 |
[Using ligustrazini and angelica sinensis treat the bleomycin-induced pulmonary fibrosis in rats].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Drugs, Chinese Herbal; Female; Image Processing, Computer-Assisted; Male; Pulmonary Fibrosis; Pyrazines; Rats; Rats, Sprague-Dawley | 1996 |
[The therapeutic effect of ligustrazin and salvia miltiorrhiza on the gene expression of alpha1 (I) and alpha1 (III) procollagen in rat pulmonary fibrosis].
Topics: Animals; Collagen Type I; Collagen Type III; Male; Phytotherapy; Procollagen; Pulmonary Fibrosis; Pyrazines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Salvia miltiorrhiza | 1999 |
[Effects of Salviae miltiorrhizae. Ligustrazini and hydrocortisone on the bleomycin-induced lung fibrosis in mice].
Topics: Animals; Bleomycin; Drug Combinations; Drugs, Chinese Herbal; Hydrocortisone; Male; Mice; Phenanthrolines; Plant Extracts; Pulmonary Fibrosis; Pyrazines; Salvia miltiorrhiza | 1987 |
[Prevention of the reacutization of chronic bronchitis with sulfamethopyrazine].
Topics: Aged; Asthma; Bronchiectasis; Bronchitis; Chronic Disease; Humans; Male; Middle Aged; Pulmonary Emphysema; Pulmonary Fibrosis; Pyrazines | 1969 |