Page last updated: 2024-08-21

pyrazines and Pregnancy

pyrazines has been researched along with Pregnancy in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19906 (15.79)18.7374
1990's9 (23.68)18.2507
2000's8 (21.05)29.6817
2010's10 (26.32)24.3611
2020's5 (13.16)2.80

Authors

AuthorsStudies
Tırmıkçıoğlu, Z1
Bugaj, JE; Dorshow, RB1
Atay, E; Bilir, A; Firat, F; Kundakci, YE1
Du, J; Jiao, Y; Zhang, J; Zhang, S1
Cai, Y; Lian, F; Wang, X; Yuan, Y; Zhao, L1
Farhadi, T; Hashemian, SM; Velayati, AA1
Caluwaerts, S1
Gu, S; Hua, X; Mou, Z; Ni, J; Shen, H; Zheng, T; Zhou, Y1
Cavenagh, J; Ingram, W; Quinn, J; Smith, D; Stevens, J; Yong, K1
Issaragrisil, S; Kheolamai, P; Klincumhom, N; Manochantr, S; Sanvoranart, T; Supokawej, A; U-Pratya, Y; Wattanapanitch, M1
Chen, ZJ; Hu, CX; Jin, S; Li, SW; Lin, YF; Ling, Y; Wang, MH; Yao, MZ1
Aprea, E; Bergamaschi, M; Betta, E; Biasioli, F; Bittante, G; Cecchinato, A; Cipolat-Gotet, C; Gasperi, F1
Guo, L; Liu, H; Liu, J; Ma, S; Nan, C; Song, G; Yan, D; Zhao, Z1
Ahn, JW; Cheon, J; Jo, YS; Lee, G; Park, KM1
Elisaf, MS; Florentin, M; Liberopoulos, EN; Mikhailidis, DP1
Li, XL; Liu, D; Zheng, QL1
Wang, XF; Zhao, MQ1
Fujihara, H; Ohta, A; Sano, M; Yamada, K1
Fang, MR; Li, JC1
Bemis, JC; Gasiewicz, TA; Henry, EC; Henry, O; Kende, AS1
Cutfield, WS; Gluckman, PD; Hofman, PL; Lobie, PE; Vickers, MH1
Burdock, GA; Carabin, IG1
Miyamoto, G; Sasabe, H1
Liu, SY; Xu, YY; Zhu, JY1
Matoba, Y; Matsui, S; Matsumori, A; Sasayama, S; Uchida, A1
Jemiolo, B; Novotny, M2
Fujihara, H; Kobayashi, Y; Ohta, A; Yamada, K1
Ohmori, K; Ohta, A; Sugawara, S; Yamada, K1
Ma, T; Wen, L; Xu, J1
Fan, S; Jiang, X; Zeng, S1
Lorke, D; Machemer, L1
Ohta, A; Takahashi, H; Yamada, K1
Huang, YL; Qian, XH; Wu, SP1
Carollo, F; Dardanoni, L; Spanó, C1
Ambrogi, V; Goldaniga, GC; Maraone, C; Pianezzola, E; Valzelli, G1
Khera, KS; Whitta, LL1
Bret, AJ; Durieux, R1

Reviews

2 review(s) available for pyrazines and Pregnancy

ArticleYear
A review on favipiravir: the properties, function, and usefulness to treat COVID-19.
    Expert review of anti-infective therapy, 2021, Volume: 19, Issue:8

    Topics: Adult; Amides; Antiviral Agents; COVID-19 Drug Treatment; Female; Humans; Pregnancy; Pyrazines

2021
Sitagliptin in clinical practice: a new approach in the treatment of type 2 diabetes.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:10

    Topics: Adult; Aged; Blood Pressure; Child; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Lipids; Male; Pregnancy; Pyrazines; Sitagliptin Phosphate; Triazoles

2008

Trials

2 trial(s) available for pyrazines and Pregnancy

ArticleYear
[Study on treatment of early onset of severe pre-eclampsia by salviae injection and ligustrazine injection in combining with Western medicine].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2010, Volume: 30, Issue:3

    Topics: Adult; Drugs, Chinese Herbal; Female; Humans; Integrative Medicine; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Prospective Studies; Pyrazines; Salvia miltiorrhiza; Young Adult

2010
[Treatment of hypertension syndrome of pregnancy with ligustrazine].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1991, Volume: 11, Issue:9

    Topics: Adult; Drug Evaluation; Female; Humans; Magnesium Sulfate; Platelet Aggregation Inhibitors; Pre-Eclampsia; Pregnancy; Pyrazines; Vasodilator Agents

1991

Other Studies

34 other study(ies) available for pyrazines and Pregnancy

ArticleYear
Favipiravir exposure and pregnancy outcome of COVID-19 patients.
    European journal of obstetrics, gynecology, and reproductive biology, 2022, Volume: 268

    Topics: Amides; COVID-19; Female; Humans; Pregnancy; Pregnancy Outcome; Pyrazines; SARS-CoV-2

2022
Absence of developmental or reproductive toxicity in rats for MB-102, a fluorescent tracer agent for point-of-care measurement of glomerular filtration rate.
    Regulatory toxicology and pharmacology : RTP, 2022, Volume: 131

    Topics: Animals; Body Weight; Cesarean Section; Coloring Agents; Dogs; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Point-of-Care Systems; Pregnancy; Pyrazines; Rabbits; Rats; Reproduction

2022
Investigation of developmental toxicity of favipiravir on fetal bone and embryonic development.
    Birth defects research, 2022, 10-15, Volume: 114, Issue:17

    Topics: Amides; Animals; Antiviral Agents; COVID-19; Embryonic Development; Female; Fetus; Pregnancy; Pyrazines; Rats; Rats, Wistar

2022
Tetramethylpyrazine attenuates placental oxidative stress, inflammatory responses and endoplasmic reticulum stress in a mouse model of gestational diabetes mellitus.
    Archives of pharmacal research, 2019, Volume: 42, Issue:12

    Topics: Administration, Oral; Animals; Diabetes, Gestational; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Female; Inflammation; Mice; Mice, Inbred C57BL; Oxidative Stress; Placenta; Pregnancy; Pyrazines

2019
Ligustrazine-induced microRNA-16-5p inhibition alleviates preeclampsia through IGF-2.
    Reproduction (Cambridge, England), 2020, Volume: 160, Issue:6

    Topics: Animals; Apoptosis; Autophagy; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation; Humans; Insulin-Like Growth Factor II; Lipopolysaccharides; MicroRNAs; Placenta; Pre-Eclampsia; Pregnancy; Pyrazines; Rats; Rats, Sprague-Dawley; Trophoblasts; Vasodilator Agents

2020
Nubia's mother: being pregnant in the time of experimental vaccines and therapeutics for Ebola.
    Reproductive health, 2017, Dec-14, Volume: 14, Issue:Suppl 3

    Topics: Africa, Western; Amides; Antibodies, Monoclonal; Antiviral Agents; Ebola Vaccines; Female; Guinea; Health Services Accessibility; Hemorrhagic Fever, Ebola; Humans; Pregnancy; Pregnancy Complications, Infectious; Pyrazines; Randomized Controlled Trials as Topic

2017
Tetramethylpyrazine reduces the consequences of nitric oxide inhibition in pregnant rats.
    Journal of cellular physiology, 2019, Volume: 234, Issue:11

    Topics: Animals; Blood Pressure; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Female; Gene Expression Regulation; Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Placenta; Pre-Eclampsia; Pregnancy; Pyrazines; Rats; Transcription Factor CHOP; Vascular Endothelial Growth Factor Receptor-1

2019
Myeloma presenting during pregnancy.
    Hematological oncology, 2014, Volume: 32, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cesarean Section; Chemoradiotherapy; Cisplatin; Combined Modality Therapy; Contraindications; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Fatal Outcome; Female; Hematopoietic Stem Cell Transplantation; Humans; Hypercalcemia; Idarubicin; Infant, Newborn; Lenalidomide; Male; Melphalan; Methylprednisolone; Multiple Myeloma; Myeloma Proteins; Osteolysis; Plasmacytoma; Postpartum Period; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Pyrazines; Remission Induction; Spinal Cord Compression; Thalidomide; Thoracic Vertebrae; Transplantation, Autologous

2014
Bortezomib enhances the osteogenic differentiation capacity of human mesenchymal stromal cells derived from bone marrow and placental tissues.
    Biochemical and biophysical research communications, 2014, May-16, Volume: 447, Issue:4

    Topics: Adipogenesis; Alkaline Phosphatase; Bone Diseases, Metabolic; Boronic Acids; Bortezomib; Cell Differentiation; Core Binding Factor Alpha 1 Subunit; Female; Humans; Integrin-Binding Sialoprotein; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Osteoporosis; Placenta; Pregnancy; Pyrazines; Sp7 Transcription Factor; Transcription Factors; Up-Regulation

2014
Expression of soluble vascular endothelial growth factor receptor-1 and placental growth factor in fetal growth restriction cases and intervention effect of tetramethylpyrazine.
    Asian Pacific journal of tropical medicine, 2014, Volume: 7, Issue:8

    Topics: Animals; Female; Fetal Development; Fetal Growth Retardation; Humans; Placenta; Placenta Growth Factor; Pregnancy; Pregnancy Proteins; Pyrazines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vascular Endothelial Growth Factor Receptor-1; Vasodilator Agents

2014
Effects of dairy system, herd within dairy system, and individual cow characteristics on the volatile organic compound profile of ripened model cheeses.
    Journal of dairy science, 2015, Volume: 98, Issue:4

    Topics: Alcohols; Aldehydes; Animals; Breeding; Cattle; Cheese; Dairying; Esters; Fatty Acids, Nonesterified; Female; Gas Chromatography-Mass Spectrometry; Ketones; Lactation; Lactones; Linear Models; Milk; Parity; Pregnancy; Pyrazines; Silage; Solid Phase Microextraction; Terpenes; Volatile Organic Compounds

2015
Tetramethylpyrazine induces differentiation of human umbilical cord-derived mesenchymal stem cells into neuron-like cells in vitro.
    International journal of oncology, 2016, Volume: 48, Issue:6

    Topics: Blotting, Western; Cell Differentiation; Female; Humans; Immunohistochemistry; Mesenchymal Stem Cells; Neurons; Phenotype; Pregnancy; Pyrazines; Umbilical Cord

2016
Teratogenic Effect of Radotinib: Case Report.
    Anticancer research, 2016, Volume: 36, Issue:12

    Topics: Adult; Benzamides; Female; Humans; Pregnancy; Pyrazines; Teratogens; Young Adult

2016
[Ligustrazine and Salvia miltiorrhiza injection solution in complementary therapy of pregnancy-induced hypertension: clinical analysis of 60 cases].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:9

    Topics: Adult; Female; Humans; Hypertension; Injections; Phytotherapy; Pregnancy; Pregnancy Complications, Cardiovascular; Pyrazines; Salvia miltiorrhiza; Solutions

2003
Effect of 2,5-dimethylpyrazine on uterine contraction in late stage of pregnant female rats.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:11

    Topics: Animals; Dose-Response Relationship, Drug; Female; Pregnancy; Pyrazines; Rats; Rats, Wistar; Uterine Contraction; Uterus

2003
[Evaluation of the efficacy of ligustrazine collaborated with magnesium sulfate in the treatment of pregnancy-induced hypertension in rats].
    Shi yan sheng wu xue bao, 2005, Volume: 38, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Female; Hypertension, Pregnancy-Induced; Kidney; Magnesium Sulfate; Male; Microscopy, Electron, Transmission; Pregnancy; Pyrazines; Rats; Rats, Sprague-Dawley

2005
A potential endogenous ligand for the aryl hydrocarbon receptor has potent agonist activity in vitro and in vivo.
    Archives of biochemistry and biophysics, 2006, Jun-01, Volume: 450, Issue:1

    Topics: Active Transport, Cell Nucleus; Animals; Atrophy; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Cell Nucleus; Cell-Free System; Cytochrome P-450 CYP1A1; Dioxins; Female; Fetus; Gene Expression Regulation, Developmental; Ligands; Mice; Mice, Transgenic; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Pregnancy; Propionates; Protein Binding; Pyrazines; Receptors, Aryl Hydrocarbon; Thymus Gland; Xenobiotics

2006
Combination therapy with acipimox enhances the effect of growth hormone treatment on linear body growth in the normal and small-for-gestational-age rat.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 291, Issue:6

    Topics: Animals; Birth Weight; Blood Pressure; Bone Development; Fatty Acids, Nonesterified; Female; Fenofibrate; Growth; Growth Hormone; Hematocrit; Hypolipidemic Agents; Insulin; Insulin-Like Growth Factor I; Liver; Male; Organ Size; Pregnancy; Pyrazines; Rats; Rats, Wistar; Tibia; Weight Gain

2006
Safety assessment of 2-ethyl-3,(5 or 6) dimethylpyrazine as a food ingredient.
    Regulatory toxicology and pharmacology : RTP, 2008, Volume: 50, Issue:3

    Topics: Animals; Carcinogenicity Tests; Eating; Female; Flavoring Agents; Food Industry; History, 20th Century; Humans; Legislation, Food; Mutagenicity Tests; Pheromones; Pregnancy; Pyrazines; Teratogens

2008
Pharmacokinetics of a new positive inotropic agent, 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu inolinone (OPC-8212), in the rat, rabbit, beagle dog and rhesus monkey.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:3A

    Topics: Animals; Autoradiography; Bile; Carbon Radioisotopes; Cardiotonic Agents; Dogs; Feces; Female; Kinetics; Liver; Macaca mulatta; Male; Pregnancy; Protein Binding; Pyrazines; Quinolines; Rabbits; Rats; Species Specificity

1984
[The effects of Salvia miltiorrhizae Bge and Ligustrazine on thromboxane A2 and prostacyclin in pregnancy induced hypertension].
    Zhonghua fu chan ke za zhi, 1994, Volume: 29, Issue:11

    Topics: Adult; Drugs, Chinese Herbal; Epoprostenol; Female; Humans; Plant Extracts; Pre-Eclampsia; Pregnancy; Pyrazines; Salvia miltiorrhiza; Thromboxane A2

1994
Treatment of virus-induced myocardial injury with a novel immunomodulating agent, vesnarinone. Suppression of natural killer cell activity and tumor necrosis factor-alpha production.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:3

    Topics: Amrinone; Animals; Cardiomyopathies; Cardiovirus Infections; Encephalomyocarditis virus; Female; Immunosuppressive Agents; Killer Cells, Natural; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Myocardium; Pregnancy; Pyrazines; Quinolines; Time Factors; Tumor Necrosis Factor-alpha

1994
Inhibition of sexual maturation in juvenile female and male mice by a chemosignal of female origin.
    Physiology & behavior, 1994, Volume: 55, Issue:3

    Topics: Animals; Body Weight; Female; Male; Mice; Mice, Inbred ICR; Organ Size; Pregnancy; Pyrazines; Seminal Vesicles; Sex Attractants; Sexual Maturation; Smell; Social Environment; Testis

1994
Long-term effect of a urinary chemosignal on reproductive fitness in female mice.
    Biology of reproduction, 1993, Volume: 48, Issue:4

    Topics: Animals; Crowding; Female; Lactation; Litter Size; Mice; Mice, Inbred ICR; Pregnancy; Pyrazines; Reproduction; Sexual Maturation

1993
Inhibitory effect of 2,5-dimethylpyrazine on oxytocic agent-induced uterine hypercontraction of normal or pregnant female rats.
    Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:5

    Topics: Animals; Dinoprost; Electromyography; Female; Injections, Intraperitoneal; Oxytocics; Oxytocin; Pregnancy; Pregnancy, Animal; Pyrazines; Rats; Rats, Wistar; Uterine Contraction

1998
Effect of 3,6-dimethylpyrazine-2-thiol on androstenedione-induced increase of uterine weight in female rats.
    Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:12

    Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Drug Interactions; Enzyme Inhibitors; Female; Organ Size; Pregnancy; Pyrazines; Rats; Rats, Wistar; Testosterone; Uterus

1999
[Study on relativity between oxygen free radical and thromboxane B2, 6-keto-PGF1 alpha during ligustrazine treatment of intrauterine growth retardation].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1998, Volume: 18, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Female; Fetal Growth Retardation; Free Radical Scavengers; Humans; Pregnancy; Pyrazines; Superoxide Dismutase; Thromboxane B2

1998
[Inhibitory effects of ligustrazine on the expression of intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1 in human umbilical vein endothelial cells induced by preeclamptic plasma].
    Zhonghua fu chan ke za zhi, 2000, Volume: 35, Issue:5

    Topics: Adult; Cells, Cultured; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Humans; Intercellular Adhesion Molecule-1; Pre-Eclampsia; Pregnancy; Pyrazines; Umbilical Veins; Vascular Cell Adhesion Molecule-1

2000
Mutagenicity studies with praziquantel, a new anthelmintic drug, in mammalian systems.
    Archives of toxicology, 1978, Jan-25, Volume: 39, Issue:3

    Topics: Animals; Cell Nucleus; Cricetinae; Cricetulus; Cyclophosphamide; Female; Genes, Dominant; Genes, Lethal; Isoquinolines; Male; Mice; Mutagens; Pregnancy; Pyrazines; Schistosomicides; Spermatogonia

1978
Effects of 2,5-dimethylpyrazine on reproductive and accessory reproductive organs in female rats.
    Research communications in chemical pathology and pharmacology, 1992, Volume: 75, Issue:1

    Topics: Animals; Chlorpromazine; Estradiol; Female; Organ Size; Ovary; Pregnancy; Progesterone; Pyrazines; Rats; Rats, Inbred Strains; Uterus

1992
[Considerations on some cases of repeated abortions probabily due to Toxoplasma gondii (author's transl)].
    Acta Europaea fertilitatis, 1972, Volume: 3, Issue:1

    Topics: Abortion, Habitual; Adult; Antibody Formation; Drug Therapy, Combination; Female; Folic Acid; Humans; Infant, Newborn; Leucomycins; Oxytetracycline; Pregnancy; Pregnancy Complications, Infectious; Pyrazines; Pyrimethamine; Skin Tests; Sulfanilamides; Toxoplasma; Toxoplasmosis; Toxoplasmosis, Congenital; Vitamins

1972
Metabolism of glipizide in the rat and dog and its tissue distribution in the mouse.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:2

    Topics: Animals; Autoradiography; Blood-Brain Barrier; Carbon Isotopes; Cyclohexanes; Female; Half-Life; Hypoglycemic Agents; Intestinal Absorption; Male; Maternal-Fetal Exchange; Mice; Pregnancy; Pyrazines; Rats; Sulfonylurea Compounds

1973
Embryopathic effects of diquat and paraquat in the rat.
    IMS, Industrial medicine and surgery, 1968, Volume: 37, Issue:7

    Topics: Animals; Embryo, Mammalian; Female; Pregnancy; Pyrazines; Pyridines; Quaternary Ammonium Compounds; Rats

1968
[Action of pyocyanine on the development of pregnancy in the guinea pig].
    Revue francaise de gynecologie et d'obstetrique, 1967, Volume: 62, Issue:9

    Topics: Animals; Female; Guinea Pigs; Pregnancy; Pregnancy, Animal; Pyrazines

1967