Compounds > pyrazines
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pyrazines and Precancerous Conditions

pyrazines has been researched along with Precancerous Conditions in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's3 (37.50)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cai, D; Feng, L; Jiao, Y; Liu, X; Mao, W; Wang, X; Wang, Y; Zhang, D; Zhang, J; Zhao, X1
Chauhan, P; Hart, KM; Liu, CG; Liu, R; Liu, X; Mao, X; Wang, L; Wei, S; Yang, WH; Yi, B; Zhang, W1
Begleiter, A; Bird, RP; Lefas, GM; Maksymiuk, AW; Sivananthan, K1
Kensler, TW; MacMillan, DL; Maxuitenko, YY; Roebuck, BD1
Ha, TG; Jang, JJ; Kim, ND; Kim, SG1
Brenner, DE; Krishnan, K; Ruffin, MT1
Curphey, TJ; Eaton, DL; Groopman, JD; Kensler, TW; Roebuck, BD1
Dolan, PM; Egner, PA; Groopman, JD; Kensler, TW; Roebuck, BD1

Reviews

1 review(s) available for pyrazines and Precancerous Conditions

ArticleYear
Chemoprevention for colorectal cancer.
    Critical reviews in oncology/hematology, 2000, Volume: 33, Issue:3

    Topics: Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Apoptosis; Arachidonic Acids; Bile Acids and Salts; Biomarkers; Calcium; Cell Cycle; Cell Transformation, Neoplastic; Clinical Trials as Topic; Colonic Polyps; Colorectal Neoplasms; DNA Methylation; DNA Repair; Eflornithine; Enzyme Inhibitors; Estrogens; Free Radical Scavengers; Genetic Predisposition to Disease; Humans; Mice; Ornithine Decarboxylase Inhibitors; Patient Compliance; Patient Selection; Polyamines; Precancerous Conditions; Pyrazines; Rats; Retinoids; Thiones; Thiophenes; Tumor Cells, Cultured; Vitamins

2000

Other Studies

7 other study(ies) available for pyrazines and Precancerous Conditions

ArticleYear
Pharmacokinetic variations of tetramethylpyrazine phosphate after oral administration in hepatic precancerous mice and its hepatoprotective effects.
    Drug development and industrial pharmacy, 2014, Volume: 40, Issue:1

    Topics: Administration, Oral; Animals; Area Under Curve; Diethylnitrosamine; Liver; Liver Neoplasms, Experimental; Male; Mice; Phosphates; Precancerous Conditions; Pyrazines

2014
FOXP3-miR-146-NF-κB Axis and Therapy for Precancerous Lesions in Prostate.
    Cancer research, 2015, Apr-15, Volume: 75, Issue:8

    Topics: Animals; Boronic Acids; Bortezomib; Cell Transformation, Neoplastic; Cells, Cultured; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Transgenic; MicroRNAs; Precancerous Conditions; Prostate; Prostatic Neoplasms; Pyrazines; Signal Transduction; Xenograft Model Antitumor Assays

2015
Inhibition of colon carcinogenesis by post-initiation induction of NQO1 in Sprague-Dawley rats.
    Oncology reports, 2009, Volume: 21, Issue:6

    Topics: Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Enzyme Induction; Glucuronosyltransferase; Glutathione Transferase; Intestinal Mucosa; Male; NAD(P)H Dehydrogenase (Quinone); Neoplasms, Experimental; Precancerous Conditions; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes; Time Factors

2009
Evaluation of the post-initiation effects of oltipraz on aflatoxin B1-induced preneoplastic foci in a rat model of hepatic tumorigenesis.
    Carcinogenesis, 1993, Volume: 14, Issue:11

    Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Body Weight; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes; Time Factors

1993
2-(Allylthio)pyrazine inhibition of aflatoxin B1-induced hepatocarcinogenesis in rats.
    Chemico-biological interactions, 1999, Jul-01, Volume: 121, Issue:2

    Topics: Aflatoxin B1; Animals; Carcinogenicity Tests; DNA Adducts; DNA, Neoplasm; Enzyme Inhibitors; Glutathione Transferase; Hepatectomy; Immunoenzyme Techniques; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Pyrazines; Rats; Rats, Sprague-Dawley; RNA

1999
Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione.
    Carcinogenesis, 1992, Volume: 13, Issue:1

    Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Enzyme Induction; gamma-Glutamyltransferase; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Thiones; Thiophenes

1992
Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones.
    Cancer research, 1987, Aug-15, Volume: 47, Issue:16

    Topics: Aflatoxin B1; Aflatoxins; Animals; Antineoplastic Agents; Cytochrome P-450 Enzyme System; DNA; Enzyme Induction; gamma-Glutamyltransferase; Glutathione Transferase; Heterocyclic Compounds; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Pyrazines; Rats; Rats, Inbred F344; Structure-Activity Relationship; Thiones; Thiophenes

1987