Page last updated: 2024-08-21

pyrazines and Pancreatitis

pyrazines has been researched along with Pancreatitis in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.71)18.2507
2000's2 (5.71)29.6817
2010's30 (85.71)24.3611
2020's1 (2.86)2.80

Authors

AuthorsStudies
Liddle, RA; Liedtke, W; Pandol, SJ; Romac, JM; Shahid, RA; Swain, SM; Vigna, SR1
Li, J; Li, ZF; Zhang, J; Zhang, S; Zhou, R1
Chen, L; Chen, Y; Jianli, Z; Yun, H1
Chang, HY; Clark, JM; Richards, TM; Segal, JB; Singh, S; Weiner, JP1
Gale, EA1
Cohen, D2
Drake, AJ; Iyer, SN; Mendez, CE; Tanenberg, RJ; West, RL1
Aston-Mourney, K; Goldstein, LC; Hull, RL; Meier, DT; Samarasekera, T; Subramanian, SL; Zraika, S1
Li, J; Liu, SS; Tsui, J; Wang, HH; Wang, XY1
Harja, E; Lord, J; Skyler, JS1
Akar, M; Aktan Kosker, T; Buyukasik, S; Ersoy, O; Solakoglu, T1
Rouse, R; Stewart, S; Xu, L; Zhang, J1
Ashikaga, T; Keino, D; Kinoshita, A; Kondoh, K; Morimoto, M; Ohyama, R; Yamashita, A1
Duke, J; Li, X; Zhang, Z1
Nandith, A; Ramachandran, A; Shetty, AS; Snehalath, C1
Cao, W; Chen, J; Cui, M; Shi, Q; Wang, C; Wang, X; Zhang, B; Zhang, G; Zhao, Y1
Arnold Chan, K; Dore, DD; Seeger, JD1
Biczó, G; Halm, G; Rakonczay, Z; Szabolcs, A; Takács, T; Tiszlavicz, L; Wittmann, T1
Dong, X; Gao, SL; Jiang, RY; Peng, JP; Wang, J; Wu, YL; Xie, QP; Zhan, YC1
Clay, RJ; Engel, SS; Goldstein, BJ; Golm, GT; Kaufman, KD; Machotka, SV; Williams-Herman, DE1
Ben Salem, C; Biour, M; Bouraoui, K; Elouni, B; Sakhri, J; Zamy, M1
Garg, R; Hussey, C; Ibrahim, S1
Chen, W; Garg, R; Pendergrass, M1
Khosroshahi, A; Stone, JH1
Ma, ML; Ou, JM; Wang, C; Wu, DJ; Zhang, XP1
Butler, PC; Elashoff, M; Elashoff, R; Gier, B; Matveyenko, AV1
Hawkes, N1
Gundert-Remy, U; Spranger, J; Stammschulte, T1
Niessen, M; Spinas, GA; Xu, L1
Masmiquel Comas, L; Nicolau Ramis, J1
Inaba, H; Kishimoto, W; Nakano, M; Nakao, A; Takagi, H; Takahashi, A1
Wang, XP; Xu, JY; Yuan, YZ1

Reviews

4 review(s) available for pyrazines and Pancreatitis

ArticleYear
Perspectives of traditional Chinese medicine in pancreas protection for acute pancreatitis.
    World journal of gastroenterology, 2017, May-28, Volume: 23, Issue:20

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Apigenin; Artemisinins; Drugs, Chinese Herbal; Emodin; Flavanones; Glucuronates; Humans; Medicine, Chinese Traditional; Pancreas; Pancreatitis; Patient Safety; Phytotherapy; Plant Extracts; Pyrazines; Resveratrol; Rheum; Salvia miltiorrhiza; Stilbenes; Sulfates

2017
[Efficacy of chemotherapy combined with bortezomib for two cases of relapsed/refractory acute lymphoblastic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Boronic Acids; Bortezomib; Cyclophosphamide; Dexamethasone; Doxorubicin; Fatal Outcome; Female; Humans; Lung Diseases, Interstitial; Octreotide; Pancreatitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proteasome Inhibitors; Pyrazines; Recurrence; Salvage Therapy; Treatment Outcome; Vincristine

2014
Sitagliptin: review of preclinical and clinical data regarding incidence of pancreatitis.
    International journal of clinical practice, 2010, Volume: 64, Issue:7

    Topics: Acute Disease; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypoglycemic Agents; Pancreatitis; Pyrazines; Randomized Controlled Trials as Topic; Risk Factors; Sitagliptin Phosphate; Triazoles

2010
Treatment approaches to IgG4-related systemic disease.
    Current opinion in rheumatology, 2011, Volume: 23, Issue:1

    Topics: Antibodies, Monoclonal, Murine-Derived; Autoimmune Diseases; Boronic Acids; Bortezomib; Glucocorticoids; Humans; Immunoglobulin G; Immunosuppressive Agents; Pancreatitis; Prognosis; Pyrazines; Recurrence; Rituximab

2011

Other Studies

31 other study(ies) available for pyrazines and Pancreatitis

ArticleYear
TRPV4 channel opening mediates pressure-induced pancreatitis initiated by Piezo1 activation.
    The Journal of clinical investigation, 2020, 05-01, Volume: 130, Issue:5

    Topics: Acinar Cells; Animals; Calcium; Calcium Signaling; Cell Death; Disease Models, Animal; Female; Ion Channels; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Pancreas; Pancreatitis; Pressure; Pyrazines; Thiadiazoles; TRPV Cation Channels

2020
Tetramethylpyrazine (TMP) protects rats against acute pancreatitis through NF-κB pathway.
    Bioengineered, 2019, Volume: 10, Issue:1

    Topics: Acute Disease; Animals; Apoptosis; Cytokines; Interleukin-6; Male; Mice; NF-kappa B; Pancreatitis; Pyrazines; Rats; Signal Transduction; Tumor Necrosis Factor-alpha

2019
Glucagonlike peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: a population-based matched case-control study.
    JAMA internal medicine, 2013, Apr-08, Volume: 173, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Case-Control Studies; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Exenatide; Female; Glucagon-Like Peptide 1; Hospitalization; Humans; Logistic Models; Male; Middle Aged; Pancreatitis; Peptides; Pyrazines; Risk Factors; Sitagliptin Phosphate; Triazoles; Venoms

2013
GLP-1 based agents and acute pancreatitis : drug safety falls victim to the three monkey paradigm.
    BMJ (Clinical research ed.), 2013, Feb-27, Volume: 346

    Topics: Acute Disease; Dipeptidyl-Peptidase IV Inhibitors; Exenatide; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Incretins; Metaphor; Pancreatitis; Peptides; Pyrazines; Sitagliptin Phosphate; Treatment Outcome; Triazoles; Venoms

2013
Two drugs for type 2 diabetes seem to raise risk of acute pancreatitis, study shows.
    BMJ (Clinical research ed.), 2013, Feb-27, Volume: 346

    Topics: Acute Disease; Animals; Diabetes Mellitus, Type 2; Evidence-Based Medicine; Exenatide; Humans; Hypoglycemic Agents; Pancreatitis; Peptides; Pyrazines; Risk Assessment; Risk Factors; Sitagliptin Phosphate; Triazoles; Venoms

2013
Pancreatitis associated with incretin-based therapies.
    Diabetes care, 2013, Volume: 36, Issue:4

    Topics: Diabetes Mellitus, Type 2; Exenatide; Humans; Hypoglycemic Agents; Incretins; Pancreatitis; Peptides; Pyrazines; Sitagliptin Phosphate; Triazoles; Venoms

2013
Reports of pancreatitis are 20-30 times more likely with GLP-1 drugs, analysis finds.
    BMJ (Clinical research ed.), 2013, Apr-23, Volume: 346

    Topics: Adamantane; Diabetes Mellitus; Dipeptides; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Linagliptin; Pancreatitis; Purines; Pyrazines; Quinazolines; Sitagliptin Phosphate; Triazoles; United States

2013
One year of sitagliptin treatment protects against islet amyloid-associated β-cell loss and does not induce pancreatitis or pancreatic neoplasia in mice.
    American journal of physiology. Endocrinology and metabolism, 2013, Aug-15, Volume: 305, Issue:4

    Topics: Animals; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Hemizygote; Humans; Hypoglycemic Agents; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Male; Metformin; Mice; Mice, Transgenic; Pancreas; Pancreatic Neoplasms; Pancreatitis; Plaque, Amyloid; Pyrazines; Random Allocation; Recombinant Proteins; Sitagliptin Phosphate; Time Factors; Triazoles

2013
Bortezomib-induced acute pancreatitis in a patient with multiple myeloma.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:6

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Female; Humans; Middle Aged; Multiple Myeloma; Pancreatitis; Pyrazines; Tomography, X-Ray Computed

2014
An analysis of characteristics of subjects examined for incretin effects on pancreatic pathology.
    Diabetes technology & therapeutics, 2013, Volume: 15, Issue:8

    Topics: Adolescent; Adult; Aged; Databases, Factual; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Exenatide; Female; Glucagon-Like Peptide-1 Receptor; Humans; Hyperplasia; Hypoglycemic Agents; Incretins; Male; Middle Aged; Models, Statistical; Pancreas; Pancreatitis; Peptides; Pyrazines; Receptors, Glucagon; Sitagliptin Phosphate; Tissue Banks; Triazoles; Venoms; Young Adult

2013
Is bortezomib a rare cause of acute pancreatitis?
    JOP : Journal of the pancreas, 2013, Nov-10, Volume: 14, Issue:6

    Topics: Abdominal Pain; Acute Disease; Antineoplastic Agents; Boronic Acids; Bortezomib; Humans; Male; Middle Aged; Multiple Myeloma; Pancreatitis; Pyrazines

2013
High fat diet and GLP-1 drugs induce pancreatic injury in mice.
    Toxicology and applied pharmacology, 2014, Apr-15, Volume: 276, Issue:2

    Topics: Acute Disease; Animals; Apoptosis; Atrophy; Diet, High-Fat; Exenatide; Glucagon-Like Peptide-1 Receptor; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Necrosis; Pancreas; Pancreatitis; Peptides; Pyrazines; Receptors, Glucagon; Sitagliptin Phosphate; Triazoles; Venoms

2014
Glucagon-like peptide 1-based therapies and risk of pancreatitis: a self-controlled case series analysis.
    Pharmacoepidemiology and drug safety, 2014, Volume: 23, Issue:3

    Topics: Adult; Aged; Cohort Studies; Databases, Factual; Exenatide; Female; Glucagon-Like Peptide 1; Humans; Male; Middle Aged; Pancreatitis; Peptides; Pyrazines; Risk Factors; Sitagliptin Phosphate; Triazoles; Venoms; Young Adult

2014
Treatment with DPP-4 inhibitors does not increase the chance of pancreatitis in patients with type 2 diabetes.
    The Journal of the Association of Physicians of India, 2013, Volume: 61, Issue:8

    Topics: Adult; Aged; Amylases; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipase; Male; Middle Aged; Pancreatitis; Pyrazines; Retrospective Studies; Risk Assessment; Sitagliptin Phosphate; Triazoles

2013
Ligustrazine alleviates acute pancreatitis by accelerating acinar cell apoptosis at early phase via the suppression of p38 and Erk MAPK pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 82

    Topics: Acinar Cells; Acute Disease; Amylases; Animals; Apoptosis; Cell Line; Cytokines; Disease Models, Animal; Down-Regulation; Inflammation Mediators; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Pancreatitis; Peroxidase; Phosphorylation; Pyrazines; Rats, Sprague-Dawley

2016
Use of a claims-based active drug safety surveillance system to assess the risk of acute pancreatitis with exenatide or sitagliptin compared to metformin or glyburide.
    Current medical research and opinion, 2009, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Databases, Factual; Exenatide; Female; Glyburide; Humans; Hypoglycemic Agents; Insurance, Health; Male; Metformin; Middle Aged; Pancreatitis; Peptides; Pyrazines; Risk Assessment; Safety; Sitagliptin Phosphate; Triazoles; United States; Venoms; Young Adult

2009
Simultaneous proteosome inhibition and heat shock protein induction by bortezomib is beneficial in experimental pancreatitis.
    European journal of pharmacology, 2009, Aug-15, Volume: 616, Issue:1-3

    Topics: Animals; Boronic Acids; Bortezomib; Heat-Shock Proteins; Male; Multienzyme Complexes; Pancreas; Pancreatitis; Protease Inhibitors; Pyrazines; Rats; Rats, Wistar

2009
The potential effect of proteasome inhibitor PS-341 on severe acute pancreatitis detected by positron emission tomography in ICR mice.
    The Journal of surgical research, 2010, Volume: 162, Issue:2

    Topics: Amylases; Animals; Apoptosis; Boronic Acids; Bortezomib; C-Reactive Protein; Ceruletide; Female; Inflammation; Interleukin-1beta; L-Lactate Dehydrogenase; Mice; Mice, Inbred ICR; Pancreatitis; Positron-Emission Tomography; Protease Inhibitors; Pyrazines; Radiography

2010
Bortezomib-induced acute pancreatitis.
    JOP : Journal of the pancreas, 2010, May-05, Volume: 11, Issue:3

    Topics: Acute Disease; Antineoplastic Agents; Boronic Acids; Bortezomib; Female; Humans; Middle Aged; Multiple Myeloma; Pancreatitis; Pyrazines

2010
Pancreatitis associated with the use of sitagliptin and orlistat combination: a case report.
    Diabetic medicine : a journal of the British Diabetic Association, 2010, Volume: 27, Issue:4

    Topics: Anti-Obesity Agents; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Lactones; Middle Aged; Orlistat; Pancreatitis; Pyrazines; Sitagliptin Phosphate; Treatment Outcome; Triazoles

2010
Sitagliptin: too many cases of pancreatitis.
    Prescrire international, 2010, Volume: 19, Issue:106

    Topics: Acute Disease; Humans; Hypoglycemic Agents; Pancreatitis; Pyrazines; Sitagliptin Phosphate; Triazoles

2010
Acute pancreatitis in type 2 diabetes treated with exenatide or sitagliptin: a retrospective observational pharmacy claims analysis.
    Diabetes care, 2010, Volume: 33, Issue:11

    Topics: Diabetes Mellitus, Type 2; Exenatide; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Pancreatitis; Peptides; Proportional Hazards Models; Pyrazines; Retrospective Studies; Sitagliptin Phosphate; Triazoles; Venoms

2010
Protective effects of ligustrazine, kakonein and Panax notoginsenosides on multiple organs in rats with severe acute pancreatitis.
    Methods and findings in experimental and clinical pharmacology, 2010, Volume: 32, Issue:9

    Topics: Acute Disease; Animals; Apoptosis; Disease Models, Animal; Drugs, Chinese Herbal; Ginsenosides; Isoflavones; Kidney; Liver; Male; Panax; Pancreas; Pancreatitis; Pyrazines; Rats; Rats, Sprague-Dawley; Saponins; Severity of Illness Index

2010
Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies.
    Gastroenterology, 2011, Volume: 141, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Exenatide; Glucagon-Like Peptide-1 Receptor; Humans; Hypoglycemic Agents; Odds Ratio; Pancreatic Neoplasms; Pancreatitis; Peptides; Pyrazines; Receptors, Glucagon; Risk Assessment; Risk Factors; Sitagliptin Phosphate; Thyroid Neoplasms; Triazoles; United States; United States Food and Drug Administration; Venoms

2011
Journal withdraws article after complaints from drug manufacturers.
    BMJ (Clinical research ed.), 2011, Apr-11, Volume: 342

    Topics: Diabetes Mellitus, Type 2; Drug Industry; Editorial Policies; Exenatide; Humans; Hypoglycemic Agents; Incretins; Pancreatitis; Peptides; Periodicals as Topic; Pyrazines; Sitagliptin Phosphate; Triazoles; Venoms

2011
GLP-1-based therapies: the dilemma of uncertainty.
    Gastroenterology, 2011, Volume: 141, Issue:1

    Topics: Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Exenatide; Glucagon-Like Peptide-1 Receptor; Humans; Hypoglycemic Agents; Pancreatic Neoplasms; Pancreatitis; Peptides; Pyrazines; Receptors, Glucagon; Risk Assessment; Risk Factors; Sitagliptin Phosphate; Thyroid Neoplasms; Triazoles; Uncertainty; Venoms

2011
Pro- or anti-inflammatory properties of the adipokine dipeptidyl peptidase-4?
    Gastroenterology, 2011, Volume: 141, Issue:6

    Topics: Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypoglycemic Agents; Pancreatic Neoplasms; Pancreatitis; Peptides; Pyrazines; Receptors, Glucagon; Thyroid Neoplasms; Triazoles; Venoms

2011
Exenatide and sitagliptin: pancreatitis and pancreatic cancer. Harms on the rise.
    Prescrire international, 2011, Volume: 20, Issue:121

    Topics: Exenatide; Humans; Hypoglycemic Agents; Pancreatic Neoplasms; Pancreatitis; Peptides; Pyrazines; Sitagliptin Phosphate; Triazoles; Venoms

2011
[The new antidiabetic agents in the firing line.... safety reasons or witch hunt?].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2012, Volume: 59, Issue:1

    Topics: Animals; Breast Neoplasms; Calcitonin; Carcinoma, Medullary; Clinical Trials as Topic; Comorbidity; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Disease Susceptibility; Female; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Infections; Liraglutide; Pancreatitis; Pharmacovigilance; Pioglitazone; Pyrazines; Risk Assessment; Safety-Based Drug Withdrawals; Sitagliptin Phosphate; Species Specificity; Thiazolidinediones; Thyroid Neoplasms; Triazoles; Urinary Bladder Neoplasms

2012
Detection of superoxide free radicals in rats with acute pancreatitis.
    Pancreas, 1995, Volume: 11, Issue:2

    Topics: Acute Disease; Animals; Ceruletide; Free Radicals; Imidazoles; Kinetics; Luminescent Measurements; Male; Pancreas; Pancreatitis; Pyrazines; Rats; Rats, Wistar; Superoxide Dismutase; Superoxides

1995
[Therapeutic effects and mechanisms of tetramethylpyrazine on lung injury in acute haemorrhagic necrotizing pancreatitis in rats].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1993, Volume: 13, Issue:10

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Free Radical Scavengers; Lipid Peroxides; Lung; Necrosis; Pancreatitis; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Thromboxane B2

1993