pyrazines has been researched along with Osteosarcoma in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 4 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, F; Geng, Z; Hu, L; Huang, Q; Li, X; Liu, S; Liu, X; Song, Q; Wang, H; Yin, Q; Zhu, Y | 1 |
| Amthor, B; Blattmann, C; Heidler, CL; Huber, PE; Kovac, M; Kulozik, AE; Neu-Yilik, G; Perez, RL; Roth, EK; Thiemann, M | 1 |
| Gondhowiardjo, S; Gu, W; Kakoti, S; Kato, R; Ohno, T; Oike, T; Permata, TBM; Sato, H; Sato, I; Shibata, A; Suzuki, K; Tsushima, Y; Uchihara, Y; Yamauchi, M; Yasuhara, T; Yoshimatsu, Y | 1 |
| Demir, B; Demir, E; Sütcüoğlu, O; Ünsal, O; Yazıcı, O | 1 |
| Davaadelger, B; Duan, L; Gitelis, S; Maki, CG; Perez, RE; Zhou, Y | 1 |
| Briaire-de Bruijn, IH; Cleton-Jansen, AM; Hassan, AB; Hogendoorn, PC; Kuijjer, ML; Meza-Zepeda, LA; Myklebost, O; Peterse, EF; Serra, M; van den Akker, BE | 1 |
| Fu, Q; Wang, Y; Zhao, W | 1 |
| Benes, CH; Bersani, F; Boussin, FD; Bryll, AR; Cox, KE; Flynn, RL; Ganem, NJ; Haber, DA; Jeitany, M; Pineda, JR; Suvà, ML; Wakimoto, H; Zou, L | 1 |
| Massey, AJ | 1 |
| Benavidez, D; Eliseev, RA; Shapovalov, Y; Zuch, D | 1 |
10 other study(ies) available for pyrazines and Osteosarcoma
| Article | Year |
|---|---|
VE-822, a novel DNA Holliday junction stabilizer, inhibits homologous recombination repair and triggers DNA damage response in osteogenic sarcomas.
Topics: Antineoplastic Agents; Cell Line, Tumor; DNA; DNA Damage; DNA Repair; Doxorubicin; Humans; Isoxazoles; Osteosarcoma; Pyrazines; Recombination, Genetic | 2021 |
Prexasertib (LY2606368) reduces clonogenic survival by inducing apoptosis in primary patient-derived osteosarcoma cells and synergizes with cisplatin and talazoparib.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cisplatin; Clone Cells; Drug Synergism; Humans; Mice; Osteosarcoma; Phthalazines; Protein Kinase Inhibitors; Pyrazines; Pyrazoles; Xenograft Model Antitumor Assays | 2020 |
High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly than X-rays in human osteosarcoma U2OS cells.
Topics: Ataxia Telangiectasia Mutated Proteins; B7-H1 Antigen; Bone Neoplasms; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Heavy Ion Radiotherapy; Humans; Imaging, Three-Dimensional; Interferon Regulatory Factor-1; Linear Energy Transfer; Morpholines; Neoplasm Proteins; Osteosarcoma; Phosphorylation; Protein Processing, Post-Translational; Pyrazines; Pyrones; RNA, Messenger; RNA, Neoplasm; STAT1 Transcription Factor; Sulfones; Up-Regulation; X-Rays | 2021 |
A possible interaction between favipiravir and methotrexate: Drug-induced hepatotoxicity in a patient with osteosarcoma.
Topics: Amides; Antiviral Agents; Bone Neoplasms; Chemical and Drug Induced Liver Injury; COVID-19; Humans; Methotrexate; Osteosarcoma; Pharmaceutical Preparations; Pyrazines; RNA, Viral; SARS-CoV-2 | 2022 |
The IGF-1R/AKT pathway has opposing effects on Nutlin-3a-induced apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Drug Synergism; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Osteosarcoma; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazines; Receptor, IGF Type 1; Receptors, Somatomedin | 2017 |
IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma.
Topics: Blotting, Western; Bone Neoplasms; Cell Proliferation; Humans; Imidazoles; Mesenchymal Stem Cells; Neoplasm Grading; Oligonucleotide Array Sequence Analysis; Osteoblasts; Osteosarcoma; Pyrazines; Receptor, IGF Type 1; Receptor, Insulin; Signal Transduction | 2013 |
Tetramethylpyrazine inhibits osteosarcoma cell proliferation via downregulation of NF-κB in vitro and in vivo.
Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclin D1; Down-Regulation; Female; G1 Phase Cell Cycle Checkpoints; Gene Expression; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Osteosarcoma; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Transcription Factor RelA; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors.
Topics: Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Line, Tumor; DNA Helicases; Gene Knockdown Techniques; Glioma; HeLa Cells; Homologous Recombination; Humans; Nuclear Proteins; Osteosarcoma; Promyelocytic Leukemia Protein; Pyrazines; Replication Protein A; RNA, Untranslated; Sulfones; Telomerase; Telomere; Telomere Homeostasis; Telomeric Repeat Binding Protein 2; Transcription Factors; Tumor Suppressor Proteins; X-linked Nuclear Protein | 2015 |
Inhibition of ATR-dependent feedback activation of Chk1 sensitises cancer cells to Chk1 inhibitor monotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Bone Neoplasms; Cell Proliferation; Checkpoint Kinase 1; Colorectal Neoplasms; DNA Damage; DNA-Activated Protein Kinase; Dose-Response Relationship, Drug; Histones; HT29 Cells; Humans; Indoles; Isoxazoles; Molecular Targeted Therapy; Nuclear Proteins; Osteosarcoma; Protein Kinase Inhibitors; Pyrazines; Pyridones; Signal Transduction; Time Factors | 2016 |
Proteasome inhibition with bortezomib suppresses growth and induces apoptosis in osteosarcoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Boronic Acids; Bortezomib; Cell Line, Tumor; DNA Primers; Humans; Immunohistochemistry; Mice; Mice, Nude; Osteosarcoma; Proteasome Inhibitors; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous | 2010 |