pyrazines has been researched along with Osteoarthritis in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Bian, Y; He, J; Hu, S; Wang, S | 1 |
| Li, H; Li, P; Li, W; Yin, D; Zhang, Y; Zhuo, H; Zou, L | 1 |
| Chen, A; Guo, F; Hu, W; Li, F; Zhang, W | 1 |
| Blancuzzi, V; Ganu, VS; Goldberg, RL; Ludewig, R; MacPherson, LJ; O'Byrne, EM; Parker, DT; Roberts, ED; Singh, HN; Wilson, D | 1 |
| Pratta, MA | 1 |
| Blancuzzi, V; Doughty, JR; Goldberg, RL; O'Byrne, E; Singh, HN; Spirito, S | 1 |
| Gaillarde, B; Nove-Josserand, G; Ortonne, JP; Philippe, LP; Plauchu, M; Pugiat, M | 1 |
7 other study(ies) available for pyrazines and Osteoarthritis
| Article | Year |
|---|---|
Tetramethylpyrazine alleviates endoplasmic reticulum stress‑activated apoptosis and related inflammation in chondrocytes.
Topics: Animals; Apoptosis; Chondrocytes; Endoplasmic Reticulum Stress; Extracellular Matrix; Gene Expression; Gene Expression Regulation; Heat-Shock Proteins; Inflammation; Interleukin-1beta; Male; Osteoarthritis; Oxidative Stress; Pyrazines; Rats; Rats, Sprague-Dawley; Transcription Factor CHOP | 2022 |
Intra-Articular Injection of a Nanosuspension of Tetramethylpyrazine Dihydroxynaphthalenate for Stronger and Longer-Lasting Effects Against Osteoarthritis.
Topics: Animals; Injections, Intra-Articular; Ligusticum; Osteoarthritis; Pyrazines; Rats | 2021 |
Bortezomib prevents the expression of MMP-13 and the degradation of collagen type 2 in human chondrocytes.
Topics: Boronic Acids; Bortezomib; Chondrocytes; Collagen Type II; Gene Expression Regulation; Humans; Interferon Regulatory Factor-1; Janus Kinase 2; Matrix Metalloproteinase 13; Osteoarthritis; Primary Cell Culture; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Pyrazines; Signal Transduction; STAT1 Transcription Factor; Tumor Necrosis Factor-alpha | 2014 |
Oral administration of a matrix metalloproteinase inhibitor, CGS 27023A, protects the cartilage proteoglycan matrix in a partial meniscectomy model of osteoarthritis in rabbits.
Topics: Animals; Cartilage, Articular; Hindlimb; Hydroxamic Acids; Joints; Male; Metalloendopeptidases; Osteoarthritis; Protease Inhibitors; Proteoglycans; Pyrazines; Rabbits; Sulfonamides | 1995 |
Biological evaluation of matrix metalloproteinase inhibitors, 18 May 1995, New York.
Topics: Animals; Humans; Hydroxamic Acids; Metalloendopeptidases; Osteoarthritis; Protease Inhibitors; Proteoglycans; Pyrazines; Sulfonamides | 1995 |
The effect of CGS 27023A on the level of 3B3 (-) epitope in a rabbit meniscectomy model.
Topics: Animals; Enzyme-Linked Immunosorbent Assay; Epitopes; Glucuronates; Glucuronic Acid; Hydroxamic Acids; Kinetics; Knee Joint; Male; Menisci, Tibial; Metalloendopeptidases; Osteoarthritis; Protease Inhibitors; Pyrazines; Rabbits; Sulfonamides | 1997 |
[Value of pyrazinobutazone in the treatment of various inflammatory conditions].
Topics: Anti-Inflammatory Agents; Arthritis; Drug Tolerance; Neuralgia; Osteoarthritis; Osteoporosis; Phenylbutazone; Phlebitis; Pyrazines; Rheumatic Diseases; Spondylitis | 1972 |